Πέμπτη 20 Αυγούστου 2020

 


Brazil nut prevents oxidative DNA damage in type 2 diabetes patients.
Related Articles Brazil nut prevents oxidative DNA damage in type 2 diabetes patients. Drug Chem Toxicol. 2020 Aug 18;:1-7 Authors: Macan TP, de Amorim TA, Damiani AP, Beretta ÂCDL, Magenis ML, Vilela TC, Teixeira JP, Andrade VM Abstract The Brazil nut (Bertholletia excelsa, H.B.K.) originating from the Amazon region is one of the richest known sources of selenium (Se), a micronutrient that is essential and required for optimal physiological...
pubmed: "drug chem toxicol"[...
Thu Aug 20, 2020 13:46
Ameliorative effects of hexane extract of Garcinia kola seeds Heckel (Clusiaceae) in cisplatin-induced hepatorenal toxicity in mice.
Related Articles Ameliorative effects of hexane extract of Garcinia kola seeds Heckel (Clusiaceae) in cisplatin-induced hepatorenal toxicity in mice. Drug Chem Toxicol. 2020 Aug 18;:1-11 Authors: Folayan A, Akani E, Adebayo OA, Akanni OO, Owumi SE, Tijani AS, Adaramoye OA Abstract Garcinia kola seed is used to manage liver diseases in ethnomedicine. However, there is limited information on its role in Cisplatin (CIS)-induced toxicity. Here,...
pubmed: "drug chem toxicol"[...
Thu Aug 20, 2020 13:46
Effect of Podophyllotoxin Conjugated Stearic Acid Grafted Chitosan Oligosaccharide Micelle on Human Glioma Cells.
Related Articles Effect of Podophyllotoxin Conjugated Stearic Acid Grafted Chitosan Oligosaccharide Micelle on Human Glioma Cells. J Korean Neurosurg Soc. 2020 Aug 20;: Authors: Wang GH, Shen HP, Huang X, Jiang XH, Jin CS, Chu ZM Abstract Objective: To study the physiochemical characteristics of podophyllotoxin (PPT) conjugated stearic acid grafted chitosan oligosaccharide micelle (PPT-CSO-SA), and evaluate the ability of the potential antineoplastic...
pubmed: "j korean neurosurg ...
Thu Aug 20, 2020 18:31
Gender Differences in Postoperative Pain, Nausea and Vomiting After Elective Laparoscopic Cholecystectomy.
Related Articles Gender Differences in Postoperative Pain, Nausea and Vomiting After Elective Laparoscopic Cholecystectomy. World J Surg. 2020 Aug 18;: Authors: Salazar-Parra M, Guzman-Ramirez BG, Pintor-Belmontes KJ, Barbosa-Camacho FJ, Bernal-Hernández A, Cruz-Neri RU, Fuentes-Orozco C, Aguirre LLR, Rodríguez-Navarro D, Brancaccio-Pérez IV, Esparza-Estrada I, Cervantes-Pérez E, Cervantes-Guevara G, Cervantes-Cardona GA, González-Ojeda A Abstract ...
pubmed: "world j surg"[jour]
Thu Aug 20, 2020 13:04
Simple Wound Irrigation in the Postoperative Treatment for Surgically Drained Spontaneous Soft Tissue Abscesses: A Prospective, Randomized Controlled Trial.
Related Articles Simple Wound Irrigation in the Postoperative Treatment for Surgically Drained Spontaneous Soft Tissue Abscesses: A Prospective, Randomized Controlled Trial. World J Surg. 2020 Aug 18;: Authors: Oehme F, Rühle A, Börnert K, Hempel S, Link BC, Babst R, Metzger J, Beeres FJ Abstract BACKGROUND: Soft tissue abscesses are among the most frequently encountered medical problems treated by different surgeons. Standard therapy remains...
pubmed: "world j surg"[jour]
Thu Aug 20, 2020 13:04
Meta-Analysis and Meta-Regression of Risk Factors for Surgical Site Infections in Hepatic and Pancreatic Resection.
Related Articles Meta-Analysis and Meta-Regression of Risk Factors for Surgical Site Infections in Hepatic and Pancreatic Resection. World J Surg. 2020 Aug 18;: Authors: Mentor K, Ratnayake B, Akter N, Alessandri G, Sen G, French JJ, Manas DM, Hammond JS, Pandanaboyana S Abstract BACKGROUND: The risk factors for surgical site infection (SSI) after HPB surgery are poorly defined. This meta-analysis aimed to quantify the SSI rates and risk factors...
pubmed: "world j surg"[jour]
Thu Aug 20, 2020 13:04
We Asked the Experts: Global Surgery-Seeing Beyond the Silo.
Related Articles We Asked the Experts: Global Surgery-Seeing Beyond the Silo. World J Surg. 2020 Aug 18;: Authors: Umutesi G, Davies J, Hedt-Gauthier BL PMID: 32812135 [PubMed - as supplied by publisher]
pubmed: "world j surg"[jour]
Thu Aug 20, 2020 13:04
Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning.
Related Articles Distinct Connectivity and Functionality of Aldehyde Dehydrogenase 1a1-Positive Nigrostriatal Dopaminergic Neurons in Motor Learning. Cell Rep. 2019 07 30;28(5):1167-1181.e7 Authors: Wu J, Kung J, Dong J, Chang L, Xie C, Habib A, Hawes S, Yang N, Chen V, Liu Z, Evans R, Liang B, Sun L, Ding J, Yu J, Saez-Atienzar S, Tang B, Khaliq Z, Lin DT, Le W, Cai H Abstract Parkinson's disease causes the most profound loss of the aldehyde...
pubmed: basal ganglia stroke...
Thu Aug 20, 2020 14:17
Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma.
Discovery of methyl 3-((2-((1-(dimethylglycyl)-5-methoxyindolin-6-yl)amino)-5-(trifluoro-methyl) pyrimidin-4-yl)amino)thiophene-2-carboxylate as a potent and selective polo-like kinase 1 (PLK1) inhibitor for combating hepatocellular carcinoma. Eur J Med Chem. 2020 Aug 08;206:112697 Authors: Deng Z, Chen G, Liu S, Li Y, Zhong J, Zhang B, Li L, Huang H, Wang Z, Xu Q, Deng X Abstract Hepatocellular carcinoma (HCC) is the second leading cause...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis.
MAP30 protein from Momordica charantia is therapeutic and has synergic activity with cisplatin against ovarian cancer in vivo by altering metabolism and inducing ferroptosis. Pharmacol Res. 2020 Aug 16;:105157 Authors: Chan DW, Yung MM, Chan YS, Xuan Y, Yang H, Xu D, Zhan JB, Chan KK, Ng TB, Ngan HY Abstract Increasing evidence shows that Traditional Chinese Medicine (TCM) has an obvious appeal for cancer treatment, but there is still...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
The PI3Kα Inhibitor DFX24 Suppresses Tumor Growth and Metastasis in Non-small Cell Lung Cancer via ERK inhibition and EPHB6 Reactivation.
The PI3Kα Inhibitor DFX24 Suppresses Tumor Growth and Metastasis in Non-small Cell Lung Cancer via ERK inhibition and EPHB6 Reactivation. Pharmacol Res. 2020 Aug 16;:105147 Authors: Fan YH, Ding HW, Kim D, Liu JY, Hong JY, Xu YN, Wang D, Yang XS, Lee SK Abstract EPHB6 is a metastasis inhibitory gene that is frequently decreased or deficiency in non-small cell lung cancer (NSCLC), which contributed to the subsequent development of distant...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Survivin modulation in the antimelanoma activity of prodiginines.
Survivin modulation in the antimelanoma activity of prodiginines. Eur J Pharmacol. 2020 Aug 16;:173465 Authors: Branco PC, Pontes CA, Rezende-Teixeira P, Amengual-Rigo P, Alves DK, Maria-Engler SS, da Silva AB, Pessoa ODL, Jimenez PC, Mollasalehi N, Chapman E, Guallar V, Machado-Neto JA, Costa-Lotufo LV Abstract Melanoma is a type of skin cancer with an elevated incidence of metastasis and chemoresistance. Such features hamper treatment...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Long Noncoding RNA LUCAT1 Promotes Multiple Myeloma Cell Growth by Regulating the TGF-β Signaling Pathway.
Related Articles Long Noncoding RNA LUCAT1 Promotes Multiple Myeloma Cell Growth by Regulating the TGF-β Signaling Pathway. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820945770 Authors: Liu Z, Gao H, Peng Q, Yang Y Abstract OBJECTIVE: Long noncoding RNAs (lncRNAs) are potential biomarkers for cancers. Nevertheless, the ability of long noncoding RNA lung cancer-associated transcript 1 in patients with multiple myeloma remains unknown....
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Enhanced antitumor activity of bovine lactoferrin through immobilization onto functionalized nano graphene oxide: an in vitro/in vivo study.
Related Articles Enhanced antitumor activity of bovine lactoferrin through immobilization onto functionalized nano graphene oxide: an in vitro/in vivo study. Drug Deliv. 2020 Dec;27(1):1236-1247 Authors: Najmafshar A, Rostami M, Varshosaz J, Norouzian D, Samsam Shariat SZA Abstract This study aims to improve the anticancer activity of bovine lactoferrin through enhancing its stability by immobilization onto graphene oxide. Bovine lactoferrin...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Phosphorylation by Aurora B kinase regulates caspase-2 activity and function.
Related Articles Phosphorylation by Aurora B kinase regulates caspase-2 activity and function. Cell Death Differ. 2020 Aug 18;: Authors: Lim Y, De Bellis D, Sandow JJ, Capalbo L, D'Avino PP, Murphy JM, Webb AI, Dorstyn L, Kumar S Abstract Mitotic catastrophe (MC) is an important oncosuppressive mechanism that serves to eliminate cells that become polyploid or aneuploid due to aberrant mitosis. Previous studies have demonstrated that the...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Unveiling the immunomodulatory properties of Haemonchus contortus adhesion regulating molecule 1 interacting with goat T cells.
Related Articles Unveiling the immunomodulatory properties of Haemonchus contortus adhesion regulating molecule 1 interacting with goat T cells. Parasit Vectors. 2020 Aug 18;13(1):424 Authors: Lu M, Tian X, Zhang Y, Aimulajiang K, Wang W, Ehsan M, Li C, Yan R, Xu L, Song X, Li X Abstract BACKGROUND: Gastrointestinal nematodes could release excretory-secretory (ES) proteins into the host environment to ensure their survival. These ES proteins...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts.
Related Articles PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts. BMC Cancer. 2020 Aug 18;20(1):775 Authors: Weigert V, Jost T, Hecht M, Knippertz I, Heinzerling L, Fietkau R, Distel LV Abstract BACKGROUND: PARP inhibitors niraparib and talazoparib are FDA approved for special cases of breast cancer. PARP is an interesting repair protein which is frequently affected in...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Synergistic Impact of Xanthorrhizol and d-δ-Tocotrienol on the Proliferation of Murine B16 Melanoma Cells and Human DU145 Prostate Carcinoma Cells.
Related Articles Synergistic Impact of Xanthorrhizol and d-δ-Tocotrienol on the Proliferation of Murine B16 Melanoma Cells and Human DU145 Prostate Carcinoma Cells. Nutr Cancer. 2020 Aug 18;:1-12 Authors: Chan D, Meister ML, Madhani CR, Elfakhani M, Yount ST, Ji X, Feresin RG, Wanders D, Mo H Abstract Isoprenoids suppress the mevalonate pathway that provides prenyl groups for the posttranslational modification of growth-regulating proteins....
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt.
Related Articles Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt. Mol Cell Biol. 2020 03 30;40(8): Authors: Liu K, Graves JD, Lee YJ, Lin FT, Lin WC Abstract Cdk2-dependent TopBP1-treslin interaction is critical for DNA replication initiation. However, it remains unclear how this association is terminated after replication initiation is finished. Here, we demonstrate that phosphorylation of TopBP1 by Akt coincides with cyclin...
pubmed: cell cycle arrest
Thu Aug 20, 2020 13:36
Dietary education programs for adults with neurological diseases: a scoping review protocol.
Related Articles Dietary education programs for adults with neurological diseases: a scoping review protocol. JBI Evid Synth. 2020 Jul 06;: Authors: Russell RD, Black LJ, Begley A Abstract OBJECTIVE: The objective of this review is to identify and map the evidence on the types of dietary education programs that have been implemented and evaluated in any setting for adults with neurological diseases. This review will also examine program characteristics,...
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
Valproate prescribing practices for women with intellectual disability across Europe.
Related Articles Valproate prescribing practices for women with intellectual disability across Europe. Acta Neurol Scand. 2020 Aug 19;: Authors: Watkins L, Reuber M, Perera B, Courtenay K, Banks R, Murphy E, Angus-Leppan H, Shankar R Abstract BACKGROUND: Valproate (VPA) is a known teratogen associated with greater risk of major congenital malformations and other neurodevelopmental sequelae than all other licensed antiepileptic medicines. To...
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
Focal to bilateral motor seizures in temporal lobe epilepsy during video-EEG monitoring: effects on surgical outcome.
Related Articles Focal to bilateral motor seizures in temporal lobe epilepsy during video-EEG monitoring: effects on surgical outcome. Acta Neurol Belg. 2020 Aug 19;: Authors: Kovačević M, Sokić D, Ristić AJ, Baščarević V, Đukić T, Pejović A, Vojvodić N Abstract The aim of this study was to determine whether the occurrence of focal to bilateral motor seizures in the course of partial drug withdrawal during video-EEG monitoring (FTBMS-M) had...
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
Cenobamate for the treatment of focal epilepsies.
Related Articles Cenobamate for the treatment of focal epilepsies. Expert Opin Pharmacother. 2020 Aug 19;:1-9 Authors: Strzelczyk A, Mann C, Willems LM, Rosenow F, Bauer S Abstract INTRODUCTION: Antiseizure drugs (ASDs) play a central and crucial role in the treatment of epilepsy patients because the majority require anticonvulsant treatment for an extended period of time. Due to the fact that 30% of patients are refractory to medical treatment,...
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
Determination of Antiepileptic Drugs Withdrawal Through EEG Hjorth Parameter Analysis.
Related Articles Determination of Antiepileptic Drugs Withdrawal Through EEG Hjorth Parameter Analysis. Int J Neural Syst. 2020 Aug 19;:2050036 Authors: Ouyang CS, Yang RC, Wu RC, Chiang CT, Lin LC Abstract The decision to continue or to stop antiepileptic drug (AED) treatment in patients with prolonged seizure remission is a critical issue. Previous studies have used certain risk factors or electroencephalogram (EEG) findings to predict seizure...
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
BRAF V600E mutation mediates FDG-methionine uptake mismatch in polymorphous low-grade neuroepithelial tumor of the young.
Related Articles BRAF V600E mutation mediates FDG-methionine uptake mismatch in polymorphous low-grade neuroepithelial tumor of the young. Acta Neuropathol Commun. 2020 Aug 18;8(1):139 Authors: Tateishi K, Ikegaya N, Udaka N, Sasame J, Hayashi T, Miyake Y, Okabe T, Minamimoto R, Murata H, Utsunomiya D, Yamanaka S, Yamamoto T Abstract We present a case of a 14-year old boy with tumor-associated refractory epilepsy. Positron emission tomography...
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
Precision medicine in sodium channelopathies - Moving beyond seizure control towards disease modification.
Related Articles Precision medicine in sodium channelopathies - Moving beyond seizure control towards disease modification. Eur J Paediatr Neurol. 2020 01;24:7 Authors: Brunklaus A PMID: 31980364 [PubMed - indexed for MEDLINE]
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
How gene discovery has transformed management of people with epilepsy.
Related Articles How gene discovery has transformed management of people with epilepsy. Eur J Paediatr Neurol. 2020 01;24:2 Authors: Scheffer IE PMID: 31952926 [PubMed - indexed for MEDLINE]
pubmed: epilepsy treatment
Thu Aug 20, 2020 13:39
Endoscopic surveillance of colorectal cancer in inflammatory bowel diseases: a review of the literature.
Related Articles Endoscopic surveillance of colorectal cancer in inflammatory bowel diseases: a review of the literature. Expert Rev Anticancer Ther. 2020 Aug 18;: Authors: Vitello A, Shahini E, Macaluso FS, Morreale GC, Sinagra E, Pallio S, Maida M Abstract INTRODUCTION: The risk of colorectal cancer (CRC) in patients with inflammatory bowel diseases (IBD) is higher compared to the general population and it is related to the type, severity,...
pubmed: expert review of ant...
Thu Aug 20, 2020 13:29
Future Oncology; +24 new citations
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
Thu Aug 20, 2020 14:40
Future Oncology; +24 new citations
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/08/20PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
Thu Aug 20, 2020 13:40
Evolving standards of care and new challenges in the management of HER2-positive breast cancer.
Related Articles Evolving standards of care and new challenges in the management of HER2-positive breast cancer. CA Cancer J Clin. 2020 Aug 19;: Authors: Choong GM, Cullen GD, O'Sullivan CC Abstract The management of human epidermal growth factor receptor (HER2)-positive breast cancer (BC) has rapidly evolved over the last 20 years. Major advances have led to US Food and Drug Administration approval of 7 HER2-targeted therapies for the treatment...
pubmed: her2-positive breast...
Thu Aug 20, 2020 16:22
Axillary Downstaging in Occult Primary Breast Cancer After Neoadjuvant Chemotherapy.
Related Articles Axillary Downstaging in Occult Primary Breast Cancer After Neoadjuvant Chemotherapy. Ann Surg Oncol. 2020 Aug 19;: Authors: Botty Van den Bruele A, Lavery J, Plitas G, Pilewskie ML Abstract BACKGROUND: Neoadjuvant chemotherapy (NAC) is increasingly used for clinically node-positive (cN+) tumors with intact primary breast cancer (IPBC) to downstage the axilla, and those who convert to cN0 may be eligible for sentinel lymph node...
pubmed: her2-positive breast...
Thu Aug 20, 2020 16:22
Drug-induced sleep endoscopy findings in surgically-naïve obese vs non-obese children.
Drug-induced sleep endoscopy findings in surgically-naïve obese vs non-obese children. Int J Pediatr Otorhinolaryngol. 2020 Aug 08;138:110289 Authors: Lookabaugh S, McKenna M, Karelsky S, Davis M, Didas A, Allen P, Faria J Abstract OBJECTIVE: To determine if drug-induced sleep endoscopy (DISE) findings are different in obese versus non-obese pediatric patients with obstructive sleep apnea (OSA) or sleep-disordered breathing (SDB). ...
pubmed: sleep apnea
Thu Aug 20, 2020 13:44
Associations of sleep quality, sleep apnea and autonomic function with insulin secretion and sensitivity: HSCAA study.
Related Articles Associations of sleep quality, sleep apnea and autonomic function with insulin secretion and sensitivity: HSCAA study. Metabol Open. 2020 Jun;6:100033 Authors: Kakutani-Hatayama M, Kadoya M, Morimoto A, Miyoshi A, Kosaka-Hamamoto K, Kusunoki Y, Shoji T, Koyama H Abstract Rationale and purpose: Although sleep disorders are shown to be involved in occurrence of diabetes, impacts of several quantitative parameters related to sleep...
pubmed: sleep apnea
Thu Aug 20, 2020 13:44
Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide.
Related Articles Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide. Physiol Rep. 2020 Aug;8(16):e14537 Authors: Bondi D, Bhandari S, Verratti V Abstract The cardiopulmonary system is a physiological cornerstone in the adaptive response to hypobaric hypoxia. Portable devices make it feasible nowadays to precisely assess the response to high altitude (HA) expeditions. In...
pubmed: sleep apnea
Thu Aug 20, 2020 13:44
CIN or not: An approach to the evaluation and management of chronic idiopathic neutrophilia.
Related Articles CIN or not: An approach to the evaluation and management of chronic idiopathic neutrophilia. Blood Rev. 2020 Aug 05;:100739 Authors: Otieno SB, Altahan A, Karri S, Kaweeta F, Lands L, Weir A Abstract Neutrophilia refers to an increase in the number of circulating neutrophils in the peripheral blood. Some common etiologies include infection, inflammatory conditions, myeloproliferative disorders, malignancies, endocrinopathies,...
pubmed: sleep apnea
Thu Aug 20, 2020 13:44
Caesium Retention Characteristics of Knifc-Pan Resin from River Water.
Related Articles Caesium Retention Characteristics of Knifc-Pan Resin from River Water. Radiat Prot Dosimetry. 2020 Aug 19;: Authors: Hegedűs M, Tazoe H, Yang G, Tamakuma Y, Hosoda M, Akata N, Tokonami S Abstract The caesium retention characteristics of a potassium-nickel hexacyanoferrate resin in a polyacrylnitrile (KNiFC-PAN) matrix were tested in fresh water over the range of 2.5-400 mL min-1. The experimental setup used 2 mL resin and...
Radiation protection dosimetry
Thu Aug 20, 2020 13:46

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