Journal of International Medical Research, Volume 48, Issue 8, August 2020. A 70-year-old woman with symptomatic bradycardia caused by persistent atrial fibrillation and atrioventricular block was referred to our institution for pacemaker implantation. After we failed to obtain adequate His bundle capture thresholds (>2.5 V at 1.0 ms) at three pacing sites, left bundle branch pacing was attempted as an alternative technique. The tip of the 3830 lead was screwed towards the left side of the interventricular...
Wed Aug 19, 2020 14:06
Journal of International Medical Research, Volume 48, Issue 8, August 2020. BackgroundExpression levels of the cell adhesion molecule syndecan-1 (SDC1) have been shown to be inversely proportional to tumor differentiation and prognosis. However, its role in the development of gallbladder cancer (GBC) remains unclear.MethodsWe knocked down SDC1 in GBC cells by RNA interference and determined its roles in cell proliferation, apoptosis, invasion, and migration by Cell Counting Kit-8, colony-formation,...
Wed Aug 19, 2020 14:06
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Cardiac tamponade is a rare complication that occurs during hemihepatectomy. This particular complication has a high degree of mortality and morbidity. A 51-year-old woman was admitted to our hospital for surgical treatment of a malignant liver tumor. During surgery, she developed sudden hemodynamic instability and signs suggesting cardiac tamponade, which was confirmed via transthoracic echocardiogram. Cardiac compression...
Wed Aug 19, 2020 12:21
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveBupivacaine is an amide local anesthetic with possible side effects that include an irregular heart rate. However, the mechanism of bupivacaine-induced cardiotoxicity has not been fully elucidated, thus we aimed to examine this mechanism.MethodsWe performed electrocardiogram recordings to detect action potential waveforms in Sprague Dawley rats after application of bupivacaine, while calcium (Ca2+) currents in neonatal...
Wed Aug 19, 2020 12:21
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveCirculating miR-146a is aberrantly expressed in patients with type 2 diabetes (T2D), probably resulting from gene polymorphisms. However, the role of polymorphism rs2910164 in T2D pathogenesis remains controversial. Thus, we designed a meta-analysis to investigate the association between rs2910164 and T2D.MethodsPubMed and Embase were searched for eligible papers in English published through September 2, 2019. Random...
Wed Aug 19, 2020 11:51
Journal of International Medical Research, Volume 48, Issue 8, August 2020. A 27-year-old man presented with intermittent right knee pain for 1 year with no previous trauma. Physical examination revealed only tenderness over the patella. Typical fluid–fluid levels were visible on magnetic resonance imaging (MRI), which highly suggested aneurysmal bone cyst (ABC) of the patella. After removal of a large window of thin cortical bone, curettage and bone grafting followed by cerclage wiring was performed....
Wed Aug 19, 2020 11:31
Journal of International Medical Research, Volume 48, Issue 8, August 2020. BackgroundSeveral lines of evidence have pointed to a protective role of natural antibodies in chronic diseases like atherosclerosis and cancer. Vascular endothelial growth factor receptor 1 (VEGFR1) and VEGFR2 are important regulators of angiogenesis and may be involved in the development of atherosclerosis. In this retrospective study, we developed an in-house enzyme-linked immunosorbent assay to assess whether natural...
Wed Aug 19, 2020 10:51
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study was performed to obtain normative data of the distal femoral cartilage thickness in healthy adults by ultrasound.MethodsThis cross-sectional study included 72 healthy adults. The demographic characteristics of the participants were recorded, and the thickness of the femoral articular cartilage was measured using a 5- to 18-MHz linear probe.ResultsSignificant statistical difference towards the male side...
Wed Aug 19, 2020 10:22
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Sclerosing encapsulating peritonitis (SEP) is a disease that is rarely encountered clinically. Preoperative diagnosis of SEP can be difficult. However, with imaging technology, such as computed tomography (CT), this condition can be diagnosed without surgery and pathological analysis. SEP is characterized by small intestine being partially or completely encased by a layer of a thick grayish-white fibrocollagenous membrane...
Wed Aug 19, 2020 09:49
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Autologous fat grafting has become increasingly popular in the field of aesthetic surgery because of its biocompatibility and low donor site morbidity. However, some fatal complications may occur following the surgery. We herein describe a woman who developed severe fat embolism after autologous fat grafting for vaginal tightening and breast augmentation surgery. The patient developed symptoms of dyspnea and hypoxemia. Computed...
Wed Aug 19, 2020 09:37
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveBody mass index (BMI) is a risk factor associated with breast cancer in postmenopausal women. This study aimed to identify the associations of BMI with clinical characteristics and management of breast cancer in female Chinese patients.MethodsClinicopathological information on 1296 women who were diagnosed with breast cancer was collected at our hospital. We recorded the clinicopathological characteristics, molecular...
Wed Aug 19, 2020 07:33
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