Related Articles An Endovascular Surgery Experience in Far-Forward Military Healthcare-A Case Series. Mil Med. 2020 Aug 19;: Authors: Coughlin DJ, Boulter JH, Miller CA, Curry BP, Glaser J, Fernandez N, Bell RS, Schuette AJ Abstract SUMMARY: INTRODUCTION: The advancement of interventional neuroradiology has drastically altered the treatment of stroke and trauma patients. These advancements in first-world hospitals, however, have rarely...
Thu Aug 20, 2020 14:30
Related Articles Animal models of Chagas disease and their translational value to drug development. Expert Opin Drug Discov. 2020 Aug 19;:1-22 Authors: Chatelain E, Scandale I Abstract INTRODUCTION: American trypanosomiasis, better known as Chagas disease, is a global public health issue. Current treatments targeting the causative parasite, Trypanosoma cruzi, are limited to two old nitroheterocyclic compounds; new, safer drugs are needed. New...
Thu Aug 20, 2020 13:36
Related Articles Supramolecular Polymer Hydrogels for Drug-Induced Tissue Regeneration. ACS Nano. 2019 05 28;13(5):5493-5501 Authors: Cheng J, Amin D, Latona J, Heber-Katz E, Messersmith PB Abstract Supramolecular polymers self-assemble into nanofibers, micelles, and other nanostructures through weak noncovalent interactions between subunits. Such systems possess attractive properties for use in a variety of practical settings such as energy,...
Thu Aug 20, 2020 18:13
Related Articles Steviol, the active principle of the Stevia sweetener, causes a reduction of the cells of the immunological system even consumed in low concentrations. Immunopharmacol Immunotoxicol. 2020 Aug 18;:1-9 Authors: Pasqualli T, Eduardha Espindola Chaves P, da Veiga Pereira L, Adílio Serpa É, Souza de Oliveira LF, Mansur Machado M Abstract Steviol is a natural diterpenoid glycoside isolated from Stevia rebaudiana Bertoni leaves and...
Thu Aug 20, 2020 18:36
Related Articles Kupffer cell inactivation ameliorates immune liver injury via TNF-α/TNFR1 signal pathway in trichloroethylene sensitized mice. Immunopharmacol Immunotoxicol. 2020 Aug 18;:1-27 Authors: Zhang JX, Xu QY, Yang Y, Li N, Zhang Y, Deng LH, Zhu QX, Shen T Abstract In our previous studies, we found that Kupffer cell activation and tumor necrosis factor (TNF)-α was increased in liver which took an important role in immune liver injury...
Thu Aug 20, 2020 18:36
Related Articles Capsaicin attenuates liver fibrosis by targeting Notch signaling to inhibit TNF-α secretion from M1 macrophages. Immunopharmacol Immunotoxicol. 2020 Aug 18;:1-10 Authors: Sheng J, Zhang B, Chen Y, Yu F Abstract BACKGROUND: Capsaicin is a chili pepper extract with multiple therapeutic properties including anti-liver fibrosis. However, the paucity of its underlying mechanisms limited its widely clinical application. METHODS:...
Thu Aug 20, 2020 18:36
Drug-induced sleep endoscopy findings in surgically-naïve obese vs non-obese children. Int J Pediatr Otorhinolaryngol. 2020 Aug 08;138:110289 Authors: Lookabaugh S, McKenna M, Karelsky S, Davis M, Didas A, Allen P, Faria J Abstract OBJECTIVE: To determine if drug-induced sleep endoscopy (DISE) findings are different in obese versus non-obese pediatric patients with obstructive sleep apnea (OSA) or sleep-disordered breathing (SDB). ...
Thu Aug 20, 2020 15:27
Related Articles Measurement of laryngeal elevation time using a flexible surface stretch sensor. J Oral Rehabil. 2020 Aug 19;: Authors: Hanaie K, Yamamoto A, Umehara K, Bessho Y, Nakamoto H, Nakayama K, Sawada K, Osawa S, Ogasawara T, Tsuneishi S, Wakasugi Y, Ishikawa A Abstract BACKGROUND: Dysphagia is a growing health problem in aging societies. An observational cohort study targeting community-dwelling populations revealed that 16% of elderly...
Thu Aug 20, 2020 15:38
Related Articles Surgical, Oncological, and Functional Outcomes of Transoral Robotic Supraglottic Laryngectomy. Laryngoscope. 2020 Jul 23;: Authors: Hans S, Chekkoury-Idrissi Y, Circiu MP, Distinguin L, Crevier-Buchman L, Lechien JR Abstract OBJECTIVES/HYPOTHESIS: To investigate the surgical, oncological, and functional outcomes of transoral robotic surgery (TORS) for the treatment of supraglottic squamous cell carcinoma. STUDY DESIGN:...
Thu Aug 20, 2020 15:38
Related Articles Manganese(III) tetrakis(1-methyl-4-pyridyl) porphyrin, a superoxide dismutase mimetic, reduces disease severity in in vitro and in vivo models for dry-eye disease. Ocul Surf. 2019 04;17(2):257-264 Authors: Žiniauskaitė A, Ragauskas S, Ghosh AK, Thapa R, Roessler AE, Koulen P, Kalesnykas G, Hakkarainen JJ, Kaja S Abstract PURPOSE: To determine the efficacy of the superoxide dismutase mimetic, manganese(III) tetrakis(1-methyl-4-pyridyl)...
Thu Aug 20, 2020 15:38
Related Articles Marked infiltration of neutrophils at the upper palpebral conjunctiva in patients with chronic graft-versus-host disease. Ocul Surf. 2019 04;17(2):295-302 Authors: Byun YS, Yoo YS, Kang MJ, Whang WJ, Na KS, Mok JW, Joo CK Abstract PURPOSE: Neutrophils may be involved in the local pathophysiology of chronic graft-versus-host disease (cGVHD). We evaluated neutrophil infiltration in cGVHD using conjunctival impression cytology...
Thu Aug 20, 2020 15:38
Related Articles Uncommon cytogenetic abnormalities identifying high-risk acute myeloid leukemia in children. Future Oncol. 2020 Aug 19;: Authors: Masetti R, Bertuccio SN, Guidi V, Cerasi S, Lonetti A, Pession A Abstract Pediatric acute myeloid leukemia (AML) represents an aggressive disease and is the leading cause of childhood leukemic mortality. The genomic landscape of pediatric AML has been recently mapped and redefined thanks to large-scale...
Thu Aug 20, 2020 13:15
Related Articles Early stage breast cancer treatment and outcome of older patients treated in an oncogeriatric care and a standard care setting: an international comparison. Breast Cancer Res Treat. 2020 Aug 19;: Authors: de Boer AZ, van de Water W, Bastiaannet E, de Glas NA, Kiderlen M, Portielje JEA, Extermann M Abstract INTRODUCTION: Since older patients with breast cancer are underrepresented in clinical trials, an oncogeriatric approach...
Thu Aug 20, 2020 13:15
Related Articles Dysregulated microRNAs in laryngeal cancer: a comprehensive meta-analysis using a robust rank aggregation approach. Future Oncol. 2020 Aug 19;: Authors: Cao Z, Guo Y, Ao Y, Zhou S Abstract We need a reasonable method of compiling data from different studies regarding the expression of microRNA (miRNA) in laryngeal squamous cell carcinoma (LSCC). The robust rank aggregation method was used to integrate the rank lists of miRNAs...
Thu Aug 20, 2020 13:15
Related Articles Excellent diagnostic performance of FNA-Tg in detecting lymph nodes metastases from papillary thyroid cancer. Future Oncol. 2020 Aug 19;: Authors: Wang J, Jiang X, Xiao G, Zhou W, Hu Y Abstract Background: Thyroglobulin washout of fine needle aspiration (FNA-Tg) has proved to be useful in detecting lymph node metastases from papillary thyroid cancer; however, the influences of thyroid gland, Hashimoto thyroiditis, serum thyroglobulin...
Thu Aug 20, 2020 13:15
Related Articles Examination of factors contributing to help-seeking behavior in accessing psychosocial support services among Japanese cancer patients: An application of the segmentation approach. Psychooncology. 2020 Aug 18;: Authors: Matsui T, Hirai K, Gondo Y, Sato S Abstract OBJECTIVE: Various psychosocial support services for cancer patients are available in Japan; however, their utilization rate is low. The present study aimed to examine...
Thu Aug 20, 2020 13:15
Related Articles Malignant peripheral nerve sheath tumors in children, adolescents, and young adults: Treatment results of five Cooperative Weichteilsarkom Studiengruppe (CWS) trials and one registry. J Surg Oncol. 2020 Aug 18;: Authors: Meister MT, Scheer M, Hallmen E, Stegmaier S, Vokuhl C, von Kalle T, Fuchs J, Münter M, Niggli F, Ladenstein R, Kazanowska B, Ljungman G, Bielack S, Koscielniak E, Klingebiel T, Cooperative Weichteilsarkom Studiengruppe [CWS]...
Thu Aug 20, 2020 13:15
Related Articles Machine learning in neurosurgery: a global survey. Acta Neurochir (Wien). 2020 Aug 18;: Authors: Staartjes VE, Stumpo V, Kernbach JM, Klukowska AM, Gadjradj PS, Schröder ML, Veeravagu A, Stienen MN, van Niftrik CHB, Serra C, Regli L Abstract BACKGROUND: Recent technological advances have led to the development and implementation of machine learning (ML) in various disciplines, including neurosurgery. Our goal was to conduct...
Thu Aug 20, 2020 13:15
Related Articles A CRISPR knockout negative screen reveals synergy between CDKs inhibitor and metformin in the treatment of human cancer in vitro and in vivo. Signal Transduct Target Ther. 2020 Aug 19;5(1):152 Authors: Ma Y, Zhu Q, Liang J, Li Y, Li M, Zhang Y, Wang X, Zeng Y, Jiao Y Abstract Laboratory research and pharmacoepidemiology provide support for metformin as a potential antitumor agent. However, the lack of a clear understanding of...
Thu Aug 20, 2020 13:15
Related Articles Education and training for image-guided adaptive brachytherapy for cervix cancer-The (GEC)-ESTRO/EMBRACE perspective. Brachytherapy. 2020 Aug 16;: Authors: Tan LT, Tanderup K, Kirisits C, Mahantshetty U, Swamidas J, Jürgenliemk-Schulz I, Lindegaard J, de Leeuw A, Nesvacil N, Assenholt M, Berger D, Diendorfer T, Dimopoulos J, Duke S, Ecker S, Fokdal L, Hellebust T, Jensen N, Kirchheiner K, Nout R, Petric P, Schmid M, Seppenwoolde Y, Sturdza A,...
Thu Aug 20, 2020 13:15
Related Articles Real world experience of poly (ADP-ribose) polymerase inhibitor use in a community oncology practice. Gynecol Oncol. 2020 Aug 15;: Authors: Eakin CM, Ewongwo A, Pendleton L, Monk BJ, Chase DM Abstract OBJECTIVE: This study aims to describe the real-world experience, including the clinical and financial burden, associated with PARP inhibitors in a large community oncology practice. METHODS: Retrospective chart review...
Thu Aug 20, 2020 13:15
Related Articles Improving clinical management of colon cancer through CONNECTION, a nation-wide colon cancer registry and stratification effort (CONNECTION II trial): rationale and protocol of a single arm intervention study. BMC Cancer. 2020 Aug 18;20(1):776 Authors: van den Berg I, van de Weerd S, Roodhart JML, Vink GR, van den Braak RRJC, Jimenez CR, Elias SG, van Vliet D, Koelink M, Hong E, van Grevenstein WMU, van Oijen MGH, Beets-Tan RGH, van Krieken JHJM,...
Thu Aug 20, 2020 13:15
Related Articles [Radiation intestinal injury in the era of precision radiotherapy]. Zhonghua Wei Chang Wai Ke Za Zhi. 2020 Aug 25;23(8):734-736 Authors: Cao XP Abstract Radiation-induced intestinal injury is caused by radiotherapy of pelvic malignant tumors. The main symptoms include persistent blood in stool, tenesmus, perianal pain, and severe intestinal perforation. Compared to conventional radiotherapy, precision radiotherapy (PT) has a...
Thu Aug 20, 2020 13:15
Related Articles Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste. Clin Cancer Res. 2019 08 15;25(16):5094-5106 Authors: Smith SJ, Tyler BM, Gould T, Veal GJ, Gorelick N, Rowlinson J, Serra R, Ritchie A, Berry P, Otto A, Choi J, Skuli N, Estevez-Cebrero M, Shakesheff KM, Brem H, Grundy RG, Rahman R Abstract PURPOSE: High-grade...
Thu Aug 20, 2020 13:15
Related Articles Dental implant surgery and risk of bleeding in patients on antithrombotic medications: a review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 25;: Authors: Bajkin BV, Wahl MJ, Miller CS Abstract OBJECTIVES: This literature review was performed to assess the risk of bleeding in dental implantation procedures in patients taking antiplatelet drugs (APs), oral anticoagulants (OACs) and direct oral...
Thu Aug 20, 2020 15:41
Related Articles Do image enhancement filters in complementary metal oxide semiconductor and photostimulable phosphor imaging systems improve the detection of fractured endodontic instruments in periapical radiography? Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 24;: Authors: Costa ED, Brasil DM, Gaêta-Araujo H, Oliveira-Santos C, Freitas DQ Abstract OBJECTIVE: The aim of this study was to evaluate the influence of image enhancement...
Thu Aug 20, 2020 15:41
Related Articles Comments on "Cardiothoracic Patients with Unilateral Vocal Fold Paralysis: Pneumonia Rates Following Injection Laryngoplasty" by Tsai et al. Ann Otol Rhinol Laryngol. 2020 Aug 19;:3489420949494 Authors: Barnes JH, Orbelo DM, Armstrong MF, Bayan SL, Lohse CM, Ekbom DC PMID: 32812446 [PubMed - as supplied by publisher]
Thu Aug 20, 2020 13:51
Related Articles Dysphagia and Dysphonia, a Pairing of Symptoms Caused by an Unusual Pair of Diseases: Castleman's Disease and Myasthenia Gravis. Ann Otol Rhinol Laryngol. 2020 Aug 19;:3489420949581 Authors: Abdelmeguid A, Rojansky R, Berry GJ, Dewan K Abstract OBJECTIVES: To describe a case of coincident Castleman's disease and myasthenia gravis that initially presented as rapidly progressive dysphagia and dysphonia and to review the unique...
Thu Aug 20, 2020 13:51
Related Articles A 28-Year-Old Man from India with SARS-Cov-2 and Pulmonary Tuberculosis Co-Infection with Central Nervous System Involvement. Am J Case Rep. 2020 Aug 19;21:e926034 Authors: Ata F, Yousaf Q, Veliyankodan Parambil J, Parengal J, Mohamedali MG, Yousaf Z Abstract BACKGROUND Tuberculosis (TB) is a great mimic of central nervous system (CNS) tumors. This mimicry may pose a challenge, as the management of both diseases is quite different....
Thu Aug 20, 2020 15:24
Related Articles Hemophagocytic Lymphohistiocytosis and Relapsing Polychondritis with Acute Myelogenous Leukemia: Case Report and Review of the Literature. Am J Case Rep. 2020 Aug 19;21:e925287 Authors: Alsaid HM, Wahdan AAM, Tahboub IN, Almakadma NM Abstract BACKGROUND This case report describes rare disease entities with possible associations that include relapsing polychondritis, a rare disease with systemic manifestations characterized by...
Thu Aug 20, 2020 15:24
Related Articles Comparison of the Clinical Course of COVID-19 Pneumonia and Acute Respiratory Distress Syndrome in 2 Passengers from the Cruise Ship Diamond Princess in February 2020. Am J Case Rep. 2020 Aug 19;21:e926835 Authors: Matsumura K, Toyoda Y, Matsumoto S, Kawai Y, Mori T, Omasa K, Fukada T, Yamada M, Kazamaki T, Furugori S, Hiroe N, Senoo S, Shimizu M, Funabiki T, Yamazaki M Abstract BACKGROUND Patients with coronavirus disease 2019...
Thu Aug 20, 2020 15:24
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