Related Articles Strategic use of obturator prostheses for the rehabilitation of oral cancer patients during the COVID-19 pandemic. Support Care Cancer. 2020 Aug 28;: Authors: Brandão TB, Migliorati CA, Vechiato-Filho AJ, Silva WG, Prado Ribeiro AC, Parise-Junior O, Kowalski LP, Santos-Silva AR Abstract During the current pandemic scenario, maxillofacial rehabilitation specialists involved with supportive care in cancer must transform its practice...
Sat Aug 29, 2020 14:15
Related Articles Dysphagia is associated with poor physical function in patients with acute heart failure: a prospective cohort study. Aging Clin Exp Res. 2020 Jun;32(6):1093-1099 Authors: Matsuo H, Yoshimura Y, Fujita S, Maeno Y Abstract BACKGROUND: Dysphagia is an important clinical problem in older adults with heart failure. Moreover, evidence is scarce regarding the prevalence and impact of dysphagia on physical function in these patients....
Sat Aug 29, 2020 14:15
Related Articles 3D printing promotes the development of drugs. Biomed Pharmacother. 2020 Aug 24;131:110644 Authors: Zhu X, Li H, Huang L, Zhang M, Fan W, Cui L Abstract 3D printing is an emerging field that can be found in medicine, electronics, aviation and other fields. 3D printing, with its personalized and highly customized characteristics, has great potential in the pharmaceutical industry. We were interested in how 3D printing can be...
Fri Aug 28, 2020 14:29
Related Articles Shorter Interval between Onset and Admission to Convalescent Rehabilitation Wards Is Associated with Improved Outcomes in Ischemic Stroke Patients. Tohoku J Exp Med. 2020;252(1):15-22 Authors: Yoshimura Y, Wakabayashi H, Momosaki R, Nagano F, Shimazu S, Shiraishi A Abstract As Japan's population ages, there is a growing interest in regional health care coordination. Our study aimed to evaluate whether the interval between onset...
Fri Aug 28, 2020 14:29
Related Articles The impact of dysphagia on quality of life in stroke patients. Medicine (Baltimore). 2020 Aug 21;99(34):e21795 Authors: Kim DY, Park HS, Park SW, Kim JH Abstract The objective of this study was to investigate the quality of life in stroke patients using a swallowing quality of life (SWAL-QOL) questionnaire. The correlation between SWAL-QOL questionnaire outcome and videofluoroscopic dysphagia scale (VDS) scores in stroke patients...
Fri Aug 28, 2020 14:29
Related Articles Efficacy of nasal high flow therapy on the coordination between breathing and swallowing of saliva during daytime nap in chronic obstructive pulmonary disease patients: A single center, randomized crossover controlled study. Medicine (Baltimore). 2020 Aug 21;99(34):e21778 Authors: Ayuse T, Hisamatsu N, Yamaguchi T, Takahashi Y, Tamada Y, Kurata S, Mishima G, Pinkham M, Tatkov S, Takahata H, Ayuse T Abstract BACKGROUND: There...
Fri Aug 28, 2020 14:29
Abstract A batch culture technique was used to evaluate dry matter (DM) digestibility of corn stover (Zea mays L.) and kudzu, Pueraria montana (Lour.) Merr. after solid-state fermentation (SSF) with a white-rot fungus, Pleurotus ostreatus (Jacq. ex Fr.) P. Kumm. Five dietary treatments consisting of mixtures of corn stover (C) and kudzu (K) in varying ratios, (1) 100C:0K, (2) 75C:25K, (3) 50C:50K, (4) 25C:75K, and (5) 0C:100K, were inoculated with P. ostreatus (MBFBL 400) and...
Sun Aug 30, 2020 03:00
Abstract Due to the inappropriate use of florfenicol in agricultural practice, florfenicol resistance has become increasingly serious. In this work, we studied the novel florfenicol resistance mechanism of an animal-derived Leclercia adecarboxylata strain R25 with high-level florfenicol resistance. A random genomic DNA library was constructed to screen the novel florfenicol resistance gene. Gene cloning, gene knockout, and complementation combined with the minimum inhibitory concentration...
Fri Aug 28, 2020 03:00
New England Journal of Medicine, Ahead of Print.
Sat Aug 29, 2020 12:06
New England Journal of Medicine, Ahead of Print.
Sat Aug 29, 2020 06:00
New England Journal of Medicine, Ahead of Print.
Sat Aug 29, 2020 06:00
New England Journal of Medicine, Ahead of Print.
Fri Aug 28, 2020 12:35
New England Journal of Medicine, Ahead of Print.
Fri Aug 28, 2020 12:34
New England Journal of Medicine, Ahead of Print.
Fri Aug 28, 2020 07:00
Acute high-altitude pulmonary edema (HAPE) is a pathology involving multifactorial triggers that are associated with ascents to altitudes over 2,500 meters above sea level (m). Here, we report two pediatric cases of reentry HAPE, from the city of Huaraz, Peru, located at 3,052 m. The characteristics of both cases were similar, wherein acclimatization to sea level and a subsequent return to the city of origin occurred, and we speculate that it was caused by activation of predisposing factors to HAPE....
Sun Aug 30, 2020 11:20
Background. While evaluating a child with multicystic liver pathology, both the congenital and acquired etiologies need to be considered. While typicality of findings on abdominal imaging makes the diagnosis of cystic echinococcosis relatively easy, choosing the appropriate line of management is equally crucial. Case Presentation. An 8-year-old previously healthy lad presented to the office with progressive upper abdominal fullness and pain for a year. Blood workup was normal. CT imaging made a diagnosis...
Sat Aug 29, 2020 18:20
Aplasia cutis congenita associated with fetus papyraceus, though rare, is well known. On the other hand, aplasia cutis congenita associated with fetus papyraceus presenting with symmetrical circumferential scarring encircling the trunk has not been previously reported. Herein, we report a 2-month-old girl with symmetrical circumferential scarring encircling the trunk associated with fetus papyraceus.
Fri Aug 28, 2020 17:35
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. Juvenile idiopathic arthritis–associated uveitis is rare in the Japanese population. In this article, we report a child whose macular edema was controlled for years after cataract surgery with adalimumab, and reviewed 26 Japanese patients in the literature. In this case report, a 4-year-old boy developed band keratopathy, posterior iris synechiae, and complicated cataract in both eyes. Oral prednisolone...
Sat Aug 29, 2020 13:47
Journal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020.
Sat Aug 29, 2020 13:47
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveWe aimed to examine the relationship between the prevalence of functional dyspepsia (FD) and lifestyle habits, to identify social factors that may contribute to psychosocial disorders.MethodsWe enrolled 759 university freshmen in this study, who were categorized into the FD group and healthy group. All participants completed the validated Self-Rating Depression Scale and Self-Rating Anxiety Scale questionnaires,...
Sat Aug 29, 2020 14:37
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo explore whether protective ileostomy is beneficial in preventing anastomotic leakage after anterior resection of rectal cancer.MethodsA total of 347 patients underwent anterior resection of rectal cancer in our hospital. Ninety-five patients were treated with protective ileostomy (treatment group), and 252 patients were not (control group). The incidences of anastomotic leakage and permanent stoma were compared...
Sat Aug 29, 2020 13:47
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Bartter syndrome is a rare inherited disease caused by CLCNKB mutation, which results in inactivation of the chloride channel Kb protein. Bartter syndrome is characterized by extreme hypokalemia, hypochloremia, metabolic alkalosis, hyperrenin-induced angiotensinemia, hyperaldosteronemia, and normal blood pressure. We herein report a case of Bartter syndrome that manifested as vomiting, hypokalemia, metabolic alkalosis, normal...
Fri Aug 28, 2020 13:45
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Posterior lumbar interbody fusion is an open surgical technique that has been widely used for the treatment of degenerative lumbar disease. However, traditional lumbar spinal fusion, especially long-segment fusion surgery, is associated with several complications. The IntraSPINE (Cousin Biotech, Wervicq-Sud, France) is a new device for non-fusion lumbar spine surgery that is used as an alternative for the treatment of degenerative...
Fri Aug 28, 2020 13:23
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo analyze the significance of intracranial pressure (ICP)-related parameters on outcome in patients with severe traumatic brain injury. The ICP-related parameters included ICP, ICP dose (DICP), regression of the correlation coefficient between amplitude and pressure (RAP), pressure reactivity index (PRx), and cerebral perfusion pressure (CPP).MethodsA retrospective analysis was performed using clinical information...
Fri Aug 28, 2020 06:16
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Autoimmune epilepsy (AE) refers to epilepsy mediated by autoantibodies or immune cells, and a large proportion of drug-resistant epilepsy cases are classified as AE. AE lacks standardized management guidelines. At present, little research has been conducted on the effectiveness of surgical treatment of AE. This paper reports a patient whose surgical treatment was ineffective before AE was diagnosed and who improved after...
Thu Aug 27, 2020 14:51
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectivesThis study aimed to investigate the epidemiology of intravenous midazolam-induced postoperative expressive aphasia (EA).MethodsThe incidence rate, risk ratio, and contributing factors to intravenous midazolam-induced postoperative EA were analyzed retrospectively in 6756 orthopedic patients. A telephone interview was conducted with patients with EA after surgery.ResultsPatients were allocated to either the midazolam...
Thu Aug 27, 2020 14:48
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Immune reconstitution inflammatory syndrome (IRIS) after starting antiretroviral treatment for human immunodeficiency virus (HIV) infection has a wide variety of causes. Delayed diagnosis and treatment of IRIS is fatal. We report a case of a 21-year-old man with HIV infection and Pneumocystis jirovecii pneumonia. The patient presented with fever and dyspnea with deterioration of pulmonary infiltrations 5 days after starting...
Thu Aug 27, 2020 14:44
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Extrapulmonary small cell carcinoma (EPSCC) affecting the external auditory canal (EAC) is uncommon. We herein report a case involving a 56-year-old man with EPSCC of the EAC who had a 48-year history of recurrent purulent discharge in both ears and a 20-day history of right ear pain and hemorrhage followed by incomplete right eyelid closure and an askew mouth. He underwent surgical removal of middle ear granulation tissue,...
Thu Aug 27, 2020 14:43
Journal of International Medical Research, Volume 48, Issue 8, August 2020. The Sprouty-related Ena/vasodilator-stimulated phosphoprotein homology-1 (EVH-1) domain (SPRED) family of proteins was discovered in 2001. These Sprouty-related tyrosine kinase-binding proteins negatively regulate a variety of growth factor-induced Ras/ERK signaling pathways. In recent years, SPRED proteins have been found to regulate vital activities such as cell development, movement, and proliferation, and to participate...
Thu Aug 27, 2020 14:36
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo compare the effectiveness of traditional and hybrid teaching strategies in pathophysiology and to conduct a survey of students’ opinions about the hybrid teaching strategy.MethodsA hybrid pathophysiology course was developed by combining traditional lectures, case- or problem-based learning, group discussion and several quizzes. A total of 167 students were assigned to the hybrid teaching group and 118 students...
Thu Aug 27, 2020 11:04
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo investigate Changweishu’s clinical effect on gastrointestinal dysfunction in patients with sepsis.MethodsFifty patients with gastrointestinal dysfunction and sepsis were randomly divided into treatment and control groups. The control group patients received routine Western medicine treatments (meropenem, noradrenaline, glutamine glue, Bifidobacterium lactis triple-strain tablet), and the treatment group patients...
Thu Aug 27, 2020 10:53
Journal of International Medical Research, Volume 48, Issue 8, August 2020. A normal disc–condyle relationship is crucial to the health and function of the temporomandibular joint. We herein introduce a novel technique that can precisely and rapidly restore the disc–condyle relationship. An initial bite rim was made, and the patient was instructed to wear this bite rim during magnetic resonance imaging (MRI) scanning. A quick MRI scan was performed, and the disc–condyle relationship and direction...
Thu Aug 27, 2020 10:48
Journal of International Medical Research, Volume 48, Issue 8, August 2020. The presence of a rhinolith is a rare condition, which can cause long-standing symptoms, such as rhinorrhea, foul-smelling discharge, nasal obstruction, and headache. A rhinolith is usually easily diagnosed by a clinical examination and a paranasal computed tomographic scan. Rhinoliths are usually found in nasal cavities, but rare locations are also possible. We report a patient who was evaluated in our clinic for nasal obstruction,...
Thu Aug 27, 2020 10:44
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectivesUtilization of self-pay vaccines worldwide is very low, especially in China; the reasons for this are unclear. We aimed to identify factors that impact the decision among Chinese mothers to utilize self-pay vaccines for their children.MethodsMothers who were hospitalized at two hospitals in Zhanjiang City and who agreed to participate by completing the required questionnaire were eligible for this study.ResultsIn...
Thu Aug 27, 2020 10:10
Abstract Purpose The dynamic response of pressure monitoring circuits must be evaluated to obtain true invasive blood pressure values. Since Gardner’s recommendations in 1981, the natural frequency and the damping coefficient have become standard parameters for anesthesiologists. In 2006, we published a new dynamic response evaluation method (step response analysis) that can plot frequency spectrum curves instantly in clinical situations....
Sat Aug 29, 2020 03:00
XXXX Abstract Background and purpose The EndoFLIP® system is a method of delineating impedance and was first designed to investigate the characteristics of the esophago‐gastric junction. In the last decade, its use was widened to investigate other sphincteric and non‐sphincteric systems of the gastrointestinal tract. The objective of the present systematic review was to summarize the available data in literature on the use of the EndoFLIP® system in the gastrointestinal tract, including...
Fri Aug 28, 2020 13:50
Fri Aug 28, 2020 13:50
As of August 24, 2020, nearly 5.7 million cases of Covid-19 had been reported in the United States, with more than 176,000 deaths. Although there is debate about the accuracy of these specific numbers — many people with mild symptoms are never tested for Covid, for example, and especially early in…
Wed Aug 26, 2020 03:00
Abstract Although various methods for improving the natural aging of skin have been examined, an effective method is currently unavailable. Therefore, in this study, we investigated the effects of Momordica charantia on the natural aging of skin of mice and how sex differences influenced these effects. To this end, we bred female and male hairless mice without ultraviolet ray irradiation and physical stress for 2 years. During the study period, mice were orally administered 50 mg/kg/day Momordica...
Sat Aug 29, 2020 13:33
Abstract Background There are an increasing number of biologic drugs in the pipeline for treating hidradenitis suppurativa (HS). Clinical trials for these drugs usually share the same clinical selection criteria. Objectives 1)To describe the clinical profile of HS patients receiving first‐line biologic treatment in an HS clinic setting, 2)to assess how this population would meet clinical criteria to participate in a clinical trial and 3)to assess treatment effectiveness at week 16 in eligible...
Sat Aug 29, 2020 13:14
Abstract Background Oral and topical zinc have been used for the treatment of acne, but there is a lack of definitive evidence for their efficacy. Objectives To (1) determine if mean serum zinc levels differ between acne patients and controls and (2) to determine the efficacy of zinc preparations in the treatment of acne. Methods A systematic review and meta‐analysis was performed according to recommended PRISMA [Preferred Reporting Items for Systematic Reviews and Meta‐Analyses]...
Sat Aug 29, 2020 13:13
ABSTRACT Background While dietary triggers have been investigated in acne and other inflammatory follicular dermatoses, there is a paucity of data on diet and HS. We sought to identify exacerbating and alleviating foods in HS patients. Methods An anonymous survey was distributed via HS Facebook support groups and in person at HS specialty clinics. Participants were asked to select all that apply from a list to indicate foods that worsen and make HS better including sweet foods, breads and...
Sat Aug 29, 2020 13:02
Abstract Objective Patients are increasingly seeking effective hair loss treatments. The internet and social media are popular sources of health information, but the quality and reliability of the content available to patients is highly variable. More than two thirds of American adults reported using YouTube in 2019. We investigated public interest in hair loss treatment information on YouTube and evaluated the quality of health information in videos with high viewer engagement. Methods...
Sat Aug 29, 2020 12:59
Abstract The condition of most patients with hyperhidrosis (HH) is known to worsen with increased temperature. However, most prior studies of oral glycopyrrolate (OGly) for the treatment of HH have assumed a stable treatment protocol, without taking into account seasonal variations in temperature. The main aim of this study is to evaluate the outcomes derived from performing a seasonal adjustment of the dose of OGly for patients with HH. A prospective study of patients who began OGly for HH, and...
Sat Aug 29, 2020 11:56
Sat Aug 29, 2020 11:46
Abstract This is the first study to evaluate the topical application of Lobelia alsinoides Lam (LT) ethanolic extract on burns in rats. A deep third‐degree burn wound was inflicted in adult male Wistar rats and the burns were dressed daily with a topical ointment formulation (Patent filed) comprising of Lobelia alsinoides Lam (5% and 10% w/w). The wound had noteworthy wound contraction and quicker eschar removal in 10% w/w LT treated groups followed by 5% w/w treated groups on comparing with the...
Fri Aug 28, 2020 21:04
Abstract Various tranexamic acid (TA) formulations have been evaluated for treating melasma, yet the effectiveness of this therapy has not been efficiently comparatively analysed. To assess and compare the therapeutic efficacy and safety of TA 5% vs hydroquinone (HQ) 4% creams in treating melasma. One hundred melasma female patients were treated with daily application of TA 5% cream on right‐sided facial lesions and HQ 4% cream on left‐sided lesions for 12 weeks. Photographic documentation using...
Fri Aug 28, 2020 13:17
Abstract The merging of psychiatry and dermatology has resulted in a relatively newer emerging field known as psychodermatology (PD). The aim of this cross sectional study was to assess knowledge, attitudes and practice patterns of Egyptian dermatologists towards psychodermatology. A cross sectional study was designed and data were collected using structured self‐administered online questionnaires. A total of 212 dermatologists completed the full questionnaire. Those with incomplete or partially...
Fri Aug 28, 2020 13:12
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