Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Aim:Thyroid cancer is the most common endocrine cancer, the incidence rate has continuously increased worldwide. However, there are still lack of effective molecular biomarkers for the diagnosis and treatment of the disease. The study was conducted to identify driver genes that may serve as potential biomarkers for the disease.Methods:The computational tools oncodriveCLUST, oncodriveFM, icages and drgap were used...
Wed Aug 19, 2020 15:40
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Background and Objective:Liver cancer is a malignancy with a poor prognosis. G protein signaling modulator 2 is mainly related to cell division and cell cycle regulation. In this review, the relationship between G protein signaling modulator 2 and clinical characteristics of patients with liver cancer has been explored, especially with respect to its prognostic value.Methods:G protein signaling modulator 2 messenger...
Wed Aug 19, 2020 14:46
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:To evaluate the diagnostic value of radial endobronchial ultrasound (R-EBUS) combination with rapid on-site evaluation (ROSE) guided transbronchial lung biopsy (TBLB) for peripheral pulmonary lesions.Methods:Peripheral pulmonary lesions identified by computed tomography underwent R-EBUS with or without ROSE randomly from February 2016 to August 2017. The diagnostic yield and the operation time were compared.Results:In...
Wed Aug 19, 2020 14:46
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Introduction:To explore association of excision repair cross-complementing 5 (ERCC5) genetic polymorphisms with cirrhosis and liver cancer.Methods:A total of 365 patients were enrolled, including control group (n = 133), cirrhosis group (n = 122), and liver cancer group (n = 110). The genotyping of ERCC5 rs2016073, rs751402, rs2094258, rs2296147, and rs2296148 was measured by using MassARRAY iPLEX technology.Results:There...
Wed Aug 19, 2020 14:46
Technology in Cancer Research &Treatment, Volume 19, Issue , January-December 2020. Objective:Long noncoding RNAs (lncRNAs) are potential biomarkers for cancers. Nevertheless, the ability of long noncoding RNA lung cancer-associated transcript 1 in patients with multiple myeloma remains unknown. The purpose of this current study was to figure out its function in multiple myeloma.Methods:Firstly, the expression of long noncoding RNA lung cancer-associated transcript 1 in cancer or normal tissues...
Wed Aug 19, 2020 14:46
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