Πέμπτη 20 Αυγούστου 2020

 Antioxidants, Vol. 9, Pages 773: WIP Modulates Oxidative Stress through NRF2/KEAP1 in Glioblastoma Cells

Antioxidants, Vol. 9, Pages 773: WIP Modulates Oxidative Stress through NRF2/KEAP1 in Glioblastoma Cells Antioxidants doi: 10.3390/antiox9090773 Authors: Maribel Escoll Diego Lastra Natalia Robledinos-Antón Francisco Wandosell Inés María Antón Antonio Cuadrado Due to their high metabolic rate, tumor cells produce exacerbated levels of reactive oxygen species that need to be under control. Wiskott–Aldrich syndrome protein (WASP)-interacting protein (WIP) is a...
Antioxidants
Thu Aug 20, 2020 03:00
Antioxidants, Vol. 9, Pages 772: The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity
Antioxidants, Vol. 9, Pages 772: The Catalytic Cycle of the Antioxidant and Cancer-Associated Human NQO1 Enzyme: Hydride Transfer, Conformational Dynamics and Functional Cooperativity Antioxidants doi: 10.3390/antiox9090772 Authors: Ernesto Anoz-Carbonell David J. Timson Angel L. Pey Milagros Medina Human NQO1 [NAD(H):quinone oxidoreductase 1] is a multi-functional and stress-inducible dimeric protein involved in the antioxidant defense, the activation of cancer prodrugs and...
Antioxidants
Thu Aug 20, 2020 03:00
Antioxidants, Vol. 9, Pages 771: Chebulic Acid Prevents Methylglyoxal-Induced Mitochondrial Dysfunction in INS-1 Pancreatic β-Cells
Antioxidants, Vol. 9, Pages 771: Chebulic Acid Prevents Methylglyoxal-Induced Mitochondrial Dysfunction in INS-1 Pancreatic β-Cells Antioxidants doi: 10.3390/antiox9090771 Authors: Hyun-jung Yoo Chung-Oui Hong Sang Keun Ha Kwang-Won Lee To investigate the anti-diabetic properties of chebulic acid (CA) associated with the prevention of methyl glyoxal (MG)-induced mitochondrial dysfunction in INS-1 pancreatic β-cells, INS-1 cells were pre-treated with CA (0.5, 1.0, and...
Antioxidants
Thu Aug 20, 2020 03:00
Antioxidants, Vol. 9, Pages 770: Addendum: Eom, T. K. et al. Dendropanax morbifera Leaf Polyphenolic Compounds: Optimal Extraction Using the Response Surface Method and Their Protective Effects against Alcohol-Induced Liver Damage. Antioxidants 2020, 9, 120
Antioxidants, Vol. 9, Pages 770: Addendum: Eom, T. K. et al. Dendropanax morbifera Leaf Polyphenolic Compounds: Optimal Extraction Using the Response Surface Method and Their Protective Effects against Alcohol-Induced Liver Damage. Antioxidants 2020, 9, 120 Antioxidants doi: 10.3390/antiox9090770 Authors: Taekil Eom Kyeoung Cheol Kim Ju-Sung Kim The authors wish to make the following corrections to this paper [...]
Antioxidants
Thu Aug 20, 2020 03:00
Atmosphere, Vol. 11, Pages 885: Measurements of Indoor and Outdoor Fine Particulate Matter during the Heating Period in Jinan, in North China: Chemical Composition, Health Risk, and Source Apportionment
Atmosphere, Vol. 11, Pages 885: Measurements of Indoor and Outdoor Fine Particulate Matter during the Heating Period in Jinan, in North China: Chemical Composition, Health Risk, and Source Apportionment Atmosphere doi: 10.3390/atmos11090885 Authors: Xiaomei Gao Weidong Gao Xiaoyan Sun Wei Jiang Ziyi Wang Wenshuai Li Fine particulate matter (PM2.5) was simultaneously collected from the indoor and outdoor environments in urban area of Jinan in North China from November to...
Atmosphere
Thu Aug 20, 2020 03:00
Beverages, Vol. 6, Pages 53: Traditional and Artisanal Beverages in Nigeria: Microbial Diversity and Safety Issues
Beverages, Vol. 6, Pages 53: Traditional and Artisanal Beverages in Nigeria: Microbial Diversity and Safety Issues Beverages doi: 10.3390/beverages6030053 Authors: Ogueri Nwaiwu Chiugo Claret Aduba Victor Chukwunenye Igbokwe Chizoba Evelyn Sam Michael Ukwuru Ukwuru A review of up to 90 articles on the microorganisms associated with important artisanal or traditional beverages in Nigeria was carried out. This resulted in an overview of the prevalent microorganisms associated...
Beverages
Thu Aug 20, 2020 03:00
Biology, Vol. 9, Pages 240: COVID-19 in Light of Seasonal Respiratory Infections
Biology, Vol. 9, Pages 240: COVID-19 in Light of Seasonal Respiratory Infections Biology doi: 10.3390/biology9090240 Authors: Irina Kiseleva Elena Grigorieva Natalie Larionova Mohammad Al Farroukh Larisa Rudenko A wide diversity of zoonotic viruses that are capable of overcoming host range barriers facilitate the emergence of new potentially pandemic viruses in the human population. When faced with a new virus that is rapidly emerging in the human population, we have a limited...
Biology
Thu Aug 20, 2020 03:00
Biology, Vol. 9, Pages 239: The Protective Role of Prenatal Alpha Lipoic Acid Supplementation against Pancreatic Oxidative Damage in Offspring of Valproic Acid-Treated Rats: Histological and Molecular Study
Biology, Vol. 9, Pages 239: The Protective Role of Prenatal Alpha Lipoic Acid Supplementation against Pancreatic Oxidative Damage in Offspring of Valproic Acid-Treated Rats: Histological and Molecular Study Biology doi: 10.3390/biology9090239 Authors: Fatma M. Ghoneim Hani Alrefai Ayman Z. Elsamanoudy Salwa M. Abo El-khair Hanaa A. Khalaf Background: Sodium valproate (VPA) is an antiepileptic drug (AED) licensed for epilepsy and used during pregnancy in various indications....
Biology
Thu Aug 20, 2020 03:00
Biology, Vol. 9, Pages 238: Formyl Peptide Receptor 1 Signaling in Acute Inflammation and Neural Differentiation Induced by Traumatic Brain Injury
Biology, Vol. 9, Pages 238: Formyl Peptide Receptor 1 Signaling in Acute Inflammation and Neural Differentiation Induced by Traumatic Brain Injury Biology doi: 10.3390/biology9090238 Authors: Roberta Fusco Enrico Gugliandolo Rosalba Siracusa Maria Scuto Marika Cordaro Ramona D’Amico Maurizio Evangelista Angelo Peli Alessio Filippo Peritore Daniela Impellizzeri Rosalia Crupi Salvatore Cuzzocrea Rosanna Di Paola Traumatic brain injury (TBI) is a shocking...
Biology
Thu Aug 20, 2020 03:00
Biology, Vol. 9, Pages 237: The Combined Effects of Varroa destructor Parasitism and Exposure to Neonicotinoids Affects Honey Bee (Apis mellifera L.) Memory and Gene Expression
Biology, Vol. 9, Pages 237: The Combined Effects of Varroa destructor Parasitism and Exposure to Neonicotinoids Affects Honey Bee (Apis mellifera L.) Memory and Gene Expression Biology doi: 10.3390/biology9090237 Authors: Nuria Morfin Paul H. Goodwin Ernesto Guzman-Novoa Honey bees (Apis mellifera L.) are exposed biotic and abiotic stressors but little is known about their combined effect and impact on neural processes such as learning and memory, which could affect behaviours...
Biology
Thu Aug 20, 2020 03:00
Biomedicines, Vol. 8, Pages 296: Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells
Biomedicines, Vol. 8, Pages 296: Ilimaquinone Induces Apoptosis and Autophagy in Human Oral Squamous Cell Carcinoma Cells Biomedicines doi: 10.3390/biomedicines8090296 Authors: Cheng-Wen Lin Li-Yuan Bai Jui-Hsin Su Chang-Fang Chiu Wei-Yu Lin Wei-Ting Huang Ming-Cheng Shih Yu-Ting Huang Jing-Lan Hu Jing-Ru Weng In this study, the anti-tumor activity of ilimaquinone (IQ), a sesquiterpene quinone isolated from marine sponge Halichondria sp., in oral squamous cell...
Biomedicines
Thu Aug 20, 2020 03:00
Biomedicines, Vol. 8, Pages 297: Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins
Biomedicines, Vol. 8, Pages 297: Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins Biomedicines doi: 10.3390/biomedicines8090297 Authors: Chunfang Xie Laura-Oana Albulescu Mátyás A. Bittenbinder Govert W. Somsen Freek J. Vonk Nicholas R. Casewell Jeroen Kool Animal-derived antivenoms are the only specific therapies currently available for the treatment of snake envenoming, but these products have a number...
Biomedicines
Thu Aug 20, 2020 03:00
Biomedicines, Vol. 8, Pages 295: The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases
Biomedicines, Vol. 8, Pages 295: The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases Biomedicines doi: 10.3390/biomedicines8090295 Authors: Antonio J. López-Gambero Carlos Sanjuan Pedro Jesús Serrano-Castro Juan Suárez Fernando Rodríguez de Fonseca Inositols are sugar-like compounds that are widely distributed in nature and are a part of membrane molecules, participating as second messengers in several...
Biomedicines
Thu Aug 20, 2020 03:00
Biomedicines, Vol. 8, Pages 293: Skin Inflammation and Testicular Function: Dermatitis Causes Male Infertility via Skin-Derived Cytokines
Biomedicines, Vol. 8, Pages 293: Skin Inflammation and Testicular Function: Dermatitis Causes Male Infertility via Skin-Derived Cytokines Biomedicines doi: 10.3390/biomedicines8090293 Authors: Ai Umaoka Hiroki Takeuchi Kento Mizutani Naohiro Seo Yoshiaki Matsushima Koji Habe Kohei Hagimori Yukie Yamaguchi Tomoaki Ikeda Keiichi Yamanaka The medical comorbidities including skin diseases are associated with male infertility. The most common cause of male infertility...
Biomedicines
Thu Aug 20, 2020 03:00
Biomedicines, Vol. 8, Pages 294: Isocitrate Dehydrogenase Mutations in Glioma: Genetics, Biochemistry, and Clinical Indications
Biomedicines, Vol. 8, Pages 294: Isocitrate Dehydrogenase Mutations in Glioma: Genetics, Biochemistry, and Clinical Indications Biomedicines doi: 10.3390/biomedicines8090294 Authors: Yang Liu Fengchao Lang Fu-Ju Chou Kareem A. Zaghloul Chunzhang Yang Mutations in isocitrate dehydrogenase (IDH) are commonly observed in lower-grade glioma and secondary glioblastomas. IDH mutants confer a neomorphic enzyme activity that converts α-ketoglutarate to an oncometabolite...
Biomedicines
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1213: Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters
Biomolecules, Vol. 10, Pages 1213: Insight into the Anticancer Activity of Copper(II) 5-Methylenetrimethylammonium-Thiosemicarbazonates and Their Interaction with Organic Cation Transporters Biomolecules doi: 10.3390/biom10091213 Authors: Milunović Palamarciuc Sirbu Shova Dumitrescu Dvoranová Rapta Petrasheuskaya Enyedy Spengler Ilic Sitte Lubec Arion A series of four water-soluble salicylaldehyde thiosemicarbazones with a positively...
Biomolecules
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1212: Low Doses of Cuscuta reflexa Extract Act as Natural Biostimulants to Improve the Germination Vigor, Growth, and Grain Yield of Wheat Grown under Water Stress: Photosynthetic Pigments, Antioxidative Defense Mechanisms, and Nutrient Acquisition
Biomolecules, Vol. 10, Pages 1212: Low Doses of Cuscuta reflexa Extract Act as Natural Biostimulants to Improve the Germination Vigor, Growth, and Grain Yield of Wheat Grown under Water Stress: Photosynthetic Pigments, Antioxidative Defense Mechanisms, and Nutrient Acquisition Biomolecules doi: 10.3390/biom10091212 Authors: Qasim Ali Rashida Perveen Mohamed A. El-Esawi Shafaqat Ali Syed Makhdoom Hussain Maira Amber Naeem Iqbal Muhammad Rizwan Mohammed Nasser Alyemeni...
Biomolecules
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1210: α-Lactalbumin, Amazing Calcium-Binding Protein
Biomolecules, Vol. 10, Pages 1210: α-Lactalbumin, Amazing Calcium-Binding Protein Biomolecules doi: 10.3390/biom10091210 Authors: Eugene A. Permyakov α-Lactalbumin (α-LA) is a small (Mr 14,200), acidic (pI 4–5), Ca2+-binding protein. α-LA is a regulatory component of lactose synthase enzyme system functioning in the lactating mammary gland. The protein possesses a single strong Ca2+-binding site, which can also bind Mg2+, Mn2+, Na+, K+, and some...
Biomolecules
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1211: Melatonin’s Impact on Antioxidative and Anti-Inflammatory Reprogramming in Homeostasis and Disease
Biomolecules, Vol. 10, Pages 1211: Melatonin’s Impact on Antioxidative and Anti-Inflammatory Reprogramming in Homeostasis and Disease Biomolecules doi: 10.3390/biom10091211 Authors: Diana Maria Chitimus Mihaela Roxana Popescu Suzana Elena Voiculescu Anca Maria Panaitescu Bogdan Pavel Leon Zagrean Ana-Maria Zagrean There is a growing consensus that the antioxidant and anti-inflammatory properties of melatonin are of great importance in preserving the body functions and...
Biomolecules
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1209: Improved Production and Biophysical Analysis of Recombinant Silicatein-α
Biomolecules, Vol. 10, Pages 1209: Improved Production and Biophysical Analysis of Recombinant Silicatein-α Biomolecules doi: 10.3390/biom10091209 Authors: Emily I. Sparkes Rachel A. Kettles Chisom S. Egedeuzu Natalie L. Stephenson Stephanie A. Caslin S. Yasin Tabatabaei Dakhili Lu Shin Wong Silicatein-α is a hydrolase found in siliceous sea sponges with a unique ability to condense and hydrolyse silicon–oxygen bonds. The enzyme is thus of interest...
Biomolecules
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1208: Decellularized Human Chorion Membrane as a Novel Biomaterial for Tissue Regeneration
Biomolecules, Vol. 10, Pages 1208: Decellularized Human Chorion Membrane as a Novel Biomaterial for Tissue Regeneration Biomolecules doi: 10.3390/biom10091208 Authors: Laura P. Frazão Joana Vieira de Castro Cristina Nogueira-Silva Nuno M. Neves Although some placenta-derived products are already used for tissue regeneration, the human chorion membrane (HCM) alone has been poorly explored. In fact, just one study uses decellularized HCM (dHCM) with native tissue architecture...
Biomolecules
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1207: Colorectal Cancer Prediction Based on Weighted Gene Co-Expression Network Analysis and Variational Auto-Encoder
Biomolecules, Vol. 10, Pages 1207: Colorectal Cancer Prediction Based on Weighted Gene Co-Expression Network Analysis and Variational Auto-Encoder Biomolecules doi: 10.3390/biom10091207 Authors: Dongmei Ai Yuduo Wang Xiaoxin Li Hongfei Pan An effective feature extraction method is key to improving the accuracy of a prediction model. From the Gene Expression Omnibus (GEO) database, which includes 13,487 genes, we obtained microarray gene expression data for 238 samples from colorectal...
Biomolecules
Thu Aug 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1206: Caveolin-3: A Causative Process of Chicken Muscular Dystrophy
Biomolecules, Vol. 10, Pages 1206: Caveolin-3: A Causative Process of Chicken Muscular Dystrophy Biomolecules doi: 10.3390/biom10091206 Authors: Tateki Kikuchi The etiology of chicken muscular dystrophy is the synthesis of aberrant WW domain containing E3 ubiquitin-protein ligase 1 (WWP1) protein made by a missense mutation of WWP1 gene. The β-dystroglycan that confers stability to sarcolemma was identified as a substrate of WWP protein, which induces the next molecular collapse....
Biomolecules
Thu Aug 20, 2020 03:00
Biosensors, Vol. 10, Pages 102: Rapid Detection of Legionella pneumophila in Drinking Water, Based on Filter Immunoassay and Chronoamperometric Measurement
Biosensors, Vol. 10, Pages 102: Rapid Detection of Legionella pneumophila in Drinking Water, Based on Filter Immunoassay and Chronoamperometric Measurement Biosensors doi: 10.3390/bios10090102 Authors: Josune J. Ezenarro Noemí Párraga-Niño Miquel Sabrià Fancisco Javier Del Campo Francesc-Xavier Muñoz-Pascual Jordi Mas Naroa Uria Legionella is a pathogenic bacterium, ubiquitous in freshwater environments and able to colonise man-made water systems from which it can...
Biosensors
Thu Aug 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 574: Age-Related Differences in Arm and Trunk Responses to First and Repeated Exposure to Laterally Induced Imbalances
Brain Sciences, Vol. 10, Pages 574: Age-Related Differences in Arm and Trunk Responses to First and Repeated Exposure to Laterally Induced Imbalances Brain Sciences doi: 10.3390/brainsci10090574 Authors: Ruth Y. Akinlosotu Nesreen Alissa John D. Sorkin George F. Wittenberg Kelly P. Westlake The objective of this study was to examine age-related differences in arm and trunk responses during first and repeated step induced balance perturbations. Young and older adults received...
Brain Sciences
Thu Aug 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 575: The Association between CAG Repeat Length and Age of Onset of Juvenile-Onset Huntington’s Disease
Brain Sciences, Vol. 10, Pages 575: The Association between CAG Repeat Length and Age of Onset of Juvenile-Onset Huntington’s Disease Brain Sciences doi: 10.3390/brainsci10090575 Authors: Jordan L. Schultz Amelia D. Moser Peg C. Nopoulos There is a known negative association between cytosine–adenine–guanine (CAG) repeat length and the age of motor onset (AMO) in adult-onset Huntington’s Disease (AOHD). This relationship is less clear in patients with...
Brain Sciences
Thu Aug 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 573: Enhancing Cognitive Performance of Healthy Czech Seniors through Non-Native Language Learning—A Mixed-Methods Pilot Study
Brain Sciences, Vol. 10, Pages 573: Enhancing Cognitive Performance of Healthy Czech Seniors through Non-Native Language Learning—A Mixed-Methods Pilot Study Brain Sciences doi: 10.3390/brainsci10090573 Authors: Blanka Klimova Gabriela Slaninova Pavel Prazak Jaroslav Kacetl Martin Valis The aim of this article is to discuss the effect of learning a non-native language on the enhancement of cognitive performance in healthy native Czech elderly. In addition, special emphasis...
Brain Sciences
Thu Aug 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 572: Cannabinoids for People with ASD: A Systematic Review of Published and Ongoing Studies
Brain Sciences, Vol. 10, Pages 572: Cannabinoids for People with ASD: A Systematic Review of Published and Ongoing Studies Brain Sciences doi: 10.3390/brainsci10090572 Authors: Laura Fusar-Poli Vito Cavone Silvia Tinacci Ilaria Concas Antonino Petralia Maria Salvina Signorelli Covadonga M. Díaz-Caneja Eugenio Aguglia The etiopathogenesis of autism spectrum disorder (ASD) remains largely unclear. Among other biological hypotheses, researchers have evidenced an imbalance...
Brain Sciences
Thu Aug 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 576: Treadmill Exercise Buffers Behavioral Alterations Related to Ethanol Binge-Drinking in Adolescent Mice
Brain Sciences, Vol. 10, Pages 576: Treadmill Exercise Buffers Behavioral Alterations Related to Ethanol Binge-Drinking in Adolescent Mice Brain Sciences doi: 10.3390/brainsci10090576 Authors: Patricia Sampedro-Piquero Carmelo Millón Román D. Moreno-Fernández María García-Fernández Zaida Diaz-Cabiale Luis Javier Santin The binge-drinking pattern of EtOH consumption, which is frequently observed in adolescents, is known to induce several neurobehavioral alterations, but...
Brain Sciences
Thu Aug 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 571: Can We Put Aside Microelectrode Recordings in Deep Brain Stimulation Surgery?
Brain Sciences, Vol. 10, Pages 571: Can We Put Aside Microelectrode Recordings in Deep Brain Stimulation Surgery? Brain Sciences doi: 10.3390/brainsci10090571 Authors: Jesús Pastor Lorena Vega-Zelaya Microelectrode recording (MER) in deep brain stimulation (DBS) surgery has long been a recognized and efficient method for defining a target. However, in recent decades, imaging techniques, including DBS surgery, have experienced significant growth. There is convincing evidence that imaging-guided...
Brain Sciences
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2360: Overhauling CAR T Cells to Improve Efficacy, Safety and Cost
Cancers, Vol. 12, Pages 2360: Overhauling CAR T Cells to Improve Efficacy, Safety and Cost Cancers doi: 10.3390/cancers12092360 Authors: Leonardo Chicaybam Martín H. Bonamino Adriana Luckow Invitti Patricia Bortman Rozenchan Igor de Luna Vieira Bryan E. Strauss Gene therapy is now surpassing 30 years of clinical experience and in that time a variety of approaches has been applied for the treatment of a wide range of pathologies. While the promise of gene therapy was over-stated...
Cancers
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Cancers, Vol. 12, Pages 2358: Romo1 Inhibition Induces TRAIL-Mediated Apoptosis in Colorectal Cancer
Cancers, Vol. 12, Pages 2358: Romo1 Inhibition Induces TRAIL-Mediated Apoptosis in Colorectal Cancer Cancers doi: 10.3390/cancers12092358 Authors: Min Jee Jo Bu Gyeom Kim Seong Hye Park Hong Jun Kim Soyeon Jeong Bo Ram Kim Jung Lim Kim Yoo Jin Na Yoon A. Jeong Hye Kyeong Yun Dae Yeong Kim Jeongsu Han Jun Young Heo Young Do Yoo Dae-Hee Lee Sang Cheul Oh Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is known to behave as an...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2359: Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients
Cancers, Vol. 12, Pages 2359: Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients Cancers doi: 10.3390/cancers12092359 Authors: Franz J. Hilke Tobias Sinnberg Axel Gschwind Heike Niessner German Demidov Teresa Amaral Stephan Ossowski Irina Bonzheim Martin Röcken Olaf Riess Claus Garbe Christopher Schroeder Andrea Forschner The detection of somatic driver mutations by next-generation...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2355: Age at Onset and Presenting Symptoms of Neurofibromatosis Type 2 as Prognostic Factors for Clinical Course of Vestibular Schwannomas
Cancers, Vol. 12, Pages 2355: Age at Onset and Presenting Symptoms of Neurofibromatosis Type 2 as Prognostic Factors for Clinical Course of Vestibular Schwannomas Cancers doi: 10.3390/cancers12092355 Authors: Isabel Gugel Florian Grimm Julian Zipfel Christian Teuber Ulrike Ernemann Lan Kluwe Marcos Tatagiba Victor-Felix Mautner Martin Ulrich Schuhmann The presenting symptoms of the tumor suppressor gene syndrome neurofibromatosis type 2 (NF2) are often non-specific...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2357: Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR
Cancers, Vol. 12, Pages 2357: Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR Cancers doi: 10.3390/cancers12092357 Authors: Bing Tan Amélie Jaulin Caroline Bund Hassiba Outilaft Corinne Wendling Marie-Pierrette Chenard Fabien Alpy A. Ercüment Cicek Izzie J. Namer Catherine Tomasetto Nassim Dali-Youcef...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2354: Targeted and Checkpoint Inhibitor Therapy of Metastatic Malignant Melanoma in Germany, 2000–2016
Cancers, Vol. 12, Pages 2354: Targeted and Checkpoint Inhibitor Therapy of Metastatic Malignant Melanoma in Germany, 2000–2016 Cancers doi: 10.3390/cancers12092354 Authors: Peter Hellmund Jochen Schmitt Martin Roessler Friedegund Meier Olaf Schoffer Targeted therapies (TT) and immune checkpoint inhibitors (ICI) have become increasingly important in the treatment of metastatic malignant melanoma in recent years. We examined implementation and effectiveness of these new therapies...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2356: Beta Human Papillomavirus 8E6 Attenuates Non-Homologous End Joining by Hindering DNA-PKcs Activity
Cancers, Vol. 12, Pages 2356: Beta Human Papillomavirus 8E6 Attenuates Non-Homologous End Joining by Hindering DNA-PKcs Activity Cancers doi: 10.3390/cancers12092356 Authors: Changkun Hu Taylor Bugbee Monica Gamez Nicholas A. Wallace Cutaneous viral infections occur in a background of near continual exposure to environmental genotoxins, like UV radiation in sunlight. Failure to repair damaged DNA is an established driver of tumorigenesis and substantial cellular resources are...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2350: Molecular Targets for the Treatment of Metastatic Colorectal Cancer
Cancers, Vol. 12, Pages 2350: Molecular Targets for the Treatment of Metastatic Colorectal Cancer Cancers doi: 10.3390/cancers12092350 Authors: Romain Cohen Thomas Pudlarz Jean-François Delattre Raphaël Colle Thierry André Over the past years, colorectal cancer (CRC) was subtyped according to its molecular and genetic characteristics, allowing the development of therapeutic strategies, based on predictive biomarkers. Biomarkers such as microsatellite instability (MSI), RAS...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2352: Low Incidence of SARS-CoV-2 in Patients with Solid Tumours on Active Treatment: An Observational Study at a Tertiary Cancer Centre in Lombardy, Italy
Cancers, Vol. 12, Pages 2352: Low Incidence of SARS-CoV-2 in Patients with Solid Tumours on Active Treatment: An Observational Study at a Tertiary Cancer Centre in Lombardy, Italy Cancers doi: 10.3390/cancers12092352 Authors: Alexia Francesca Bertuzzi Andrea Marrari Nicolò Gennaro Umberto Cariboni Michele Ciccarelli Laura Giordano Vittorio Lorenzo Quagliuolo Armando Santoro Background: The incidence and prognosis of SARS-CoV-2-positive cancer patients on active oncologic...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2351: Targeting the Calcium Signalling Machinery in Cancer
Cancers, Vol. 12, Pages 2351: Targeting the Calcium Signalling Machinery in Cancer Cancers doi: 10.3390/cancers12092351 Authors: Jason I. E. Bruce Andrew D. James Cancer is caused by excessive cell proliferation and a propensity to avoid cell death, while the spread of cancer is facilitated by enhanced cellular migration, invasion, and vascularization. Cytosolic Ca2+ is central to each of these important processes, yet to date, there are no cancer drugs currently being used clinically,...
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2353: The Diagnostic Accuracy of Mutant KRAS Detection from Pancreatic Secretions for the Diagnosis of Pancreatic Cancer: A Meta-Analysis
Cancers, Vol. 12, Pages 2353: The Diagnostic Accuracy of Mutant KRAS Detection from Pancreatic Secretions for the Diagnosis of Pancreatic Cancer: A Meta-Analysis Cancers doi: 10.3390/cancers12092353 Authors: Nikhil Patel Tatjana Petrinic Michael Silva Zahir Soonawalla Srikanth Reddy Alex Gordon-Weeks This meta-analysis aims to identify the diagnostic accuracy of mutations in the Kirsten Rat Sarcoma (KRAS) oncogene in the diagnosis of pancreatic ductal adenocarcinoma (PDAC)....
Cancers
Thu Aug 20, 2020 03:00
Cancers, Vol. 12, Pages 2349: Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia
Cancers, Vol. 12, Pages 2349: Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia Cancers doi: 10.3390/cancers12092349 Authors: Carlos Sanhueza Jimena Castillo Bennett Manuel Valenzuela-Valderrama Pamela Contreras Lorena Lobos-González América Campos Sergio Wehinger Álvaro Lladser Rolf Kiessling Lisette Leyton Andrew F.G. Quest Caveolin-1 (CAV1) is a well-established nitric oxide synthase...
Cancers
Thu Aug 20, 2020 03:00
Cells, Vol. 9, Pages 1929: Synthetic Notch-Receptor-Mediated Transmission of a Transient Signal into Permanent Information via CRISPR/Cas9-Based Genome Editing
Cells, Vol. 9, Pages 1929: Synthetic Notch-Receptor-Mediated Transmission of a Transient Signal into Permanent Information via CRISPR/Cas9-Based Genome Editing Cells doi: 10.3390/cells9091929 Authors: Malte Sgodda Susanne Alfken Axel Schambach Reto Eggenschwiler Pawel Fidzinski Michael Hummel Tobias Cantz Synthetic receptor biology and genome editing are emerging techniques, both of which are currently beginning to be used in preclinical and clinical applications. We...
Cells
Thu Aug 20, 2020 03:00
Cells, Vol. 9, Pages 1928: TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy
Cells, Vol. 9, Pages 1928: TonEBP Promotes β-Cell Survival under ER Stress by Enhancing Autophagy Cells doi: 10.3390/cells9091928 Authors: Hyun Je Kang Eun Jin Yoo Hwan Hee Lee Seung Min An Hyun Park Whaseon Lee-Kwon Soo Youn Choi Hyug Moo Kwon The endoplasmic reticulum (ER) stress response and autophagy are important cellular responses that determine cell fate and whose dysregulation is implicated in the perturbation of homeostasis and diseases. Tonicity-responsive...
Cells
Thu Aug 20, 2020 03:00
Cells, Vol. 9, Pages 1927: FGF2 Inhibits Early Pancreatic Lineage Specification during Differentiation of Human Embryonic Stem Cells
Cells, Vol. 9, Pages 1927: FGF2 Inhibits Early Pancreatic Lineage Specification during Differentiation of Human Embryonic Stem Cells Cells doi: 10.3390/cells9091927 Authors: Rabea Dettmer Karsten Cirksena Julia Münchhoff Jasmin Kresse Ulf Diekmann Isabell Niwolik Falk F. R. Buettner Ortwin Naujok Growth factors are important regulators during organ development. For many vertebrates (but not humans) it is known how they contribute to the formation and expansion of...
Cells
Thu Aug 20, 2020 03:00
Challenges, Vol. 11, Pages 18: Considerations for Comparing Video Game AI Agents with Humans
Challenges, Vol. 11, Pages 18: Considerations for Comparing Video Game AI Agents with Humans Challenges doi: 10.3390/challe11020018 Authors: Christopher R. Madan Video games are sometimes used as environments to evaluate AI agents’ ability to develop and execute complex action sequences to maximize a defined reward. However, humans cannot match the fine precision of the timed actions of AI agents; in games such as StarCraft, build orders take the place of chess opening gambits....
Challenges
Thu Aug 20, 2020 03:00
Chemosensors, Vol. 8, Pages 72: Enhanced NO2-Sensing Properties of Au-Loaded Porous In2O3 Gas Sensors at Low Operating Temperatures
Chemosensors, Vol. 8, Pages 72: Enhanced NO2-Sensing Properties of Au-Loaded Porous In2O3 Gas Sensors at Low Operating Temperatures Chemosensors doi: 10.3390/chemosensors8030072 Authors: Taro Ueda Inci Boehme Takeo Hyodo Yasuhiro Shimizu Udo Weimar Nicolae Barsan NO2-sensing properties of semiconductor gas sensors using porous In2O3 powders loaded with and without 0.5 wt% Au (Au/In2O3 and In2O3 sensors, respectively) were examined in wet air (70% relative humidity at 25...
Chemosensors
Thu Aug 20, 2020 03:00
Children, Vol. 7, Pages 107: Combined Effect of Race/Ethnicity and Type of Insurance on Reuse of Urgent Hospital-Based Services in Children Discharged with Asthma
Children, Vol. 7, Pages 107: Combined Effect of Race/Ethnicity and Type of Insurance on Reuse of Urgent Hospital-Based Services in Children Discharged with Asthma Children doi: 10.3390/children7090107 Authors: Jamie M. Pinto Sarita Wagle Lauren J. Navallo Anna Petrova Asthma is a leading cause of health disparity in children. This study explores the joint effect of race/ethnicity and insurance type on risk for reuse of urgent services within a year of hospitalization. Data were...
Children
Thu Aug 20, 2020 03:00
Diagnostics, Vol. 10, Pages 617: microRNA Expression Profile in Single Hormone Receptor-Positive Breast Cancers is Mainly Dependent on HER2 Status—A Pilot Study
Diagnostics, Vol. 10, Pages 617: microRNA Expression Profile in Single Hormone Receptor-Positive Breast Cancers is Mainly Dependent on HER2 Status—A Pilot Study Diagnostics doi: 10.3390/diagnostics10090617 Authors: Michał Kunc Marta Popęda Magdalena Niemira Anna Szałkowska Michał Bieńkowski Rafał Pęksa Aleksandra Łacko Barbara S. Radecka Marcin Braun Joanna Pikiel Maria Litwiniuk Katarzyna Pogoda Ewa Iżycka-Świeszewska Adam Krętowski Anna J. Żaczek...
Diagnostics
Thu Aug 20, 2020 03:00
Diagnostics, Vol. 10, Pages 613: A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation
Diagnostics, Vol. 10, Pages 613: A Systematic Review of the Diagnostic Methods of Small Fiber Neuropathies in Rehabilitation Diagnostics doi: 10.3390/diagnostics10090613 Authors: Rita Chiaramonte Marcello Romano Michele Vecchio This systematic review describes the several methods to diagnose and measure the severity of small fiber neuropathies and aims to guide the physician to define all the diagnostic approaches for adopting the best strategies described in the current literature....
Diagnostics
Thu Aug 20, 2020 03:00
Diagnostics, Vol. 10, Pages 615: Effectiveness of Strongyloides Recombinant IgG Immunoreactive Antigen in Detecting IgG and IgG4 Subclass Antibodies for Diagnosis of Human Strongyloidiasis Using Rapid Immunochromatographic Tests
Diagnostics, Vol. 10, Pages 615: Effectiveness of Strongyloides Recombinant IgG Immunoreactive Antigen in Detecting IgG and IgG4 Subclass Antibodies for Diagnosis of Human Strongyloidiasis Using Rapid Immunochromatographic Tests Diagnostics doi: 10.3390/diagnostics10090615 Authors: Patcharaporn Boonroumkaew Lakkhana Sadaow Oranuch Sanpool Rutchanee Rodpai Tongjit Thanchomnang Weeraya Phupiewkham Pewpan M. Intapan Wanchai Maleewong Human strongyloidiasis is an important...
Diagnostics
Thu Aug 20, 2020 03:00
Diagnostics, Vol. 10, Pages 616: The Role of EEG in the Diagnosis, Prognosis and Clinical Correlations of Dementia with Lewy Bodies—A Systematic Review
Diagnostics, Vol. 10, Pages 616: The Role of EEG in the Diagnosis, Prognosis and Clinical Correlations of Dementia with Lewy Bodies—A Systematic Review Diagnostics doi: 10.3390/diagnostics10090616 Authors: Law Todd Mehraram Schumacher Baker LeBeau Yarnall Onofrj Bonanni Thomas Taylor Despite improvements in diagnostic criteria for dementia with Lewy bodies (DLB), the ability to discriminate DLB from Alzheimer′s disease (AD) and other...
Diagnostics
Thu Aug 20, 2020 03:00
Diagnostics, Vol. 10, Pages 612: Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer
Diagnostics, Vol. 10, Pages 612: Comparison of Pteridine Normalization Methods in Urine for Detection of Bladder Cancer Diagnostics doi: 10.3390/diagnostics10090612 Authors: Piotr Kośliński Robert Pluskota Katarzyna Mądra-Gackowska Marcin Gackowski Michał J. Markuszewski Kornelia Kędziora-Kornatowska Marcin Koba Pterin compounds belong to the group of biomarkers for which an increase in interest has been observed in recent years. Available literature data point to this...
Diagnostics
Thu Aug 20, 2020 03:00
Diagnostics, Vol. 10, Pages 614: Design and Development of a Methodology Based on Expert Systems, Applied to the Treatment of Pressure Ulcers
Diagnostics, Vol. 10, Pages 614: Design and Development of a Methodology Based on Expert Systems, Applied to the Treatment of Pressure Ulcers Diagnostics doi: 10.3390/diagnostics10090614 Authors: Manuel Casal-Guisande Alberto Comesaña-Campos Jorge Cerqueiro-Pequeño José-Benito Bouza-Rodríguez The medical treatment of chronic wounds, pressure ulcers in particular, burdens healthcare systems nowadays with high expenses that result mainly from their monitoring and assessment stages....
Diagnostics
Thu Aug 20, 2020 03:00
Diversity, Vol. 12, Pages 317: Exotic Prey Facilitate Coexistence between Pumas and Culpeo Foxes in the Andes of Central Chile
Diversity, Vol. 12, Pages 317: Exotic Prey Facilitate Coexistence between Pumas and Culpeo Foxes in the Andes of Central Chile Diversity doi: 10.3390/d12090317 Authors: Christian Osorio Ana Muñoz Nicolás Guarda Cristian Bonacic Marcella Kelly Coexistence between species with similar ecological niches implies species must segregate along one or more niche axes to survive. Space, time, and trophic resources are regarded as the principal axes upon which species segregate. We...
Diversity
Thu Aug 20, 2020 03:00
Diversity, Vol. 12, Pages 316: Crenal Habitats: Sources of Water Mite (Acari: Hydrachnidia) Diversity
Diversity, Vol. 12, Pages 316: Crenal Habitats: Sources of Water Mite (Acari: Hydrachnidia) Diversity Diversity doi: 10.3390/d12090316 Authors: Ivana Pozojević Vladimir Pešić Tom Goldschmidt Sanja Gottstein Many studies emphasized the role that water mites play within the invertebrate communities of spring ecosystems, regarding species diversity and its significance within the crenal food web, as well as the specific preferences water mites exhibit towards spring typology. In...
Diversity
Thu Aug 20, 2020 03:00
EJIHPE, Vol. 10, Pages 832-847: Scientific Mapping of Gamification in Web of Science
EJIHPE, Vol. 10, Pages 832-847: Scientific Mapping of Gamification in Web of Science European Journal of Investigation in Health, Psychology and Education doi: 10.3390/ejihpe10030060 Authors: Jesús López-Belmonte Mª Elena Parra-González Adrián Segura-Robles Santiago Pozo-Sánchez Education is a constantly changing field. The new teaching processes are developed today and all teachers should be prepared. Gamification is one of the methodologies with the greatest impact on the...
European Journal of Investigation in Health, Psychology and Education
Thu Aug 20, 2020 03:00
EJIHPE, Vol. 10, Pages 816-831: Characteristics of Academic Adaptation and Subjective Well-Being in University Students with Chronic Diseases
EJIHPE, Vol. 10, Pages 816-831: Characteristics of Academic Adaptation and Subjective Well-Being in University Students with Chronic Diseases European Journal of Investigation in Health, Psychology and Education doi: 10.3390/ejihpe10030059 Authors: Rail M. Shamionov Marina V. Grigoryeva Elena S. Grinina Aleksey V. Sozonnik Studying academic adaptation and subjective well-being in students with chronic diseases can help to explain psychological compensatory mechanisms and help...
European Journal of Investigation in Health, Psychology and Education
Thu Aug 20, 2020 03:00
EJIHPE, Vol. 10, Pages 795-815: Awareness, Policy, Privacy, and More: Post-Secondary Students Voice Their Solutions to Cyberbullying
EJIHPE, Vol. 10, Pages 795-815: Awareness, Policy, Privacy, and More: Post-Secondary Students Voice Their Solutions to Cyberbullying European Journal of Investigation in Health, Psychology and Education doi: 10.3390/ejihpe10030058 Authors: Chantal Faucher Wanda Cassidy Margaret Jackson This paper discusses solutions to cyberbullying posed by post-secondary students from four Canadian universities. The qualitative data used in this analysis were drawn from one open-ended question...
European Journal of Investigation in Health, Psychology and Education
Thu Aug 20, 2020 03:00

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