Publication date: October 2020Source: Acta Histochemica, Volume 122, Issue 7Author(s): Haodong Zhou, Guy Trudel, Konstantin Alexeev, Odette Laneuville
Tue Aug 11, 2020 19:04
Zusammenfassung Hintergrund Monogen erbliche Tumorsyndrome bzw. Tumordispositionssyndrome (TDS) beruhen auf Keimbahn-/konstitutionellen Mutationen in Schlüsselgenen der Karzinogenese. Ein frühes Erkrankungsalter und eine Häufung von Tumoren eines typischen Spektrums in der Eigen- und/oder Familienanamnese sind Hinweise für das Vorliegen einer hereditären Form. Insbesondere seltene spezifische Tumoren treten relativ häufig im Rahmen...
Tue Aug 11, 2020 03:00
B7‐H3 is a member of the B7 superfamily of immune checkpoint molecules. B7‐H3 up regulation has been linked to cancer development and progression in many tumors including prostate cancer. To clarify the potential utility of B7‐H3 as a prognostic biomarker, B7‐H3 expression was analyzed by immunohistochemistry in more than 17 000 prostate cancers. Normal prostatic glands were largely B7‐H3 negative, while membranous B7‐H3 immunostaining was seen in 47.0% of analyzed cancers. B7‐H3 immunostaining was...
Mon Aug 10, 2020 18:58
Publication date: Available online 10 August 2020Source: Pathology - Research and PracticeAuthor(s): Jing Zhao, Uma Krishnamurti, Chao Zhang, Jane Meisel, Zhimin Wei, Aili Suo, Ritu Aneja, Zaibo Li, Xiaoxian Li
Tue Aug 11, 2020 16:49
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