Disruption of the ERLIN-TM6SF2-APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease. PLoS Genet. 2020 Aug 10;16(8):e1008955 Authors: Li BT, Sun M, Li YF, Wang JQ, Zhou ZM, Song BL, Luo J Abstract Non-alcoholic fatty liver disease (NAFLD) is a metabolic disorder characterized by excess lipid accumulation in the liver without significant consumption of alcohol. The transmembrane 6 superfamily member 2 (TM6SF2) E167K...
Tue Aug 11, 2020 15:55
Cannabinoids, Endocannabinoids and Sleep. Front Mol Neurosci. 2020;13:125 Authors: Kesner AJ, Lovinger DM Abstract Sleep is a vital function of the nervous system that contributes to brain and bodily homeostasis, energy levels, cognitive ability, and other key functions of a variety of organisms. Dysfunctional sleep induces neural problems and is a key part of almost all human psychiatric disorders including substance abuse disorders. The hypnotic...
Tue Aug 11, 2020 15:55
Related Articles IKIP Negatively Regulates NF-κB Activation and Inflammation through Inhibition of IKKα/β Phosphorylation. J Immunol. 2020 01 15;204(2):418-427 Authors: Wu H, Liu H, Zhao X, Zheng Y, Liu B, Zhang L, Gao C Abstract Stringent regulation of the transcription factor NF-κB signaling is essential for the activation of host immune responses and maintaining homeostasis, yet the molecular mechanisms involved in its tight regulation are...
Tue Aug 11, 2020 15:55
Related Articles Endothelin-1 inhibits size dependent lymphatic clearance of PEG-based conjugates after intra-articular injection into the rat knee. Acta Biomater. 2019 07 15;93:270-281 Authors: Doan TN, Bernard FC, McKinney JM, Dixon JB, Willett NJ Abstract Clearance of particles from the knee is an essential mechanism to maintain healthy joint homeostasis and critical to the delivery of drugs and therapeutics. One of the limitations in developing...
Tue Aug 11, 2020 15:55
Abstract Alzheimer’s disease (AD) is a complex, multicausal disorder involving several spatiotemporal scales and scientific domains. While many studies focus on specific parts of this system, the complexity of AD is rarely studied as a whole. In this work, we apply systems thinking to map out known causal mechanisms and risk factors ranging from intracellular to psychosocial scales in sporadic AD. We report on the first systemic causal loop diagram (CLD) for AD, which is the result...
Tue Aug 11, 2020 03:00
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Aug 11, 2020 16:29
150 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Aug 11, 2020 16:59
4160 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Aug 11, 2020 17:36
4160 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Aug 11, 2020 13:40
Researchers identified multiple bottlenose dolphins with high levels of mercury in their livers. Marine scientists are only beginning to understand the relationship between ocean pollutants and sea animals' health. (NOAA/Amy Van Cise /)Marine biologists have been sounding the alarm about ocean pollution since the 1950s. Up until then, many scientists believed that the ocean was large enough to dilute any human waste and protect its animal inhabitants. Over the past few decades, researchers have shown...
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Your phone can do a lot more than check email. (Photo by Ashkan Forouzani on Unsplash/)Our smartphones are fantastic at conveying information, from the serious to the silly. But it’s easy to forget that they’re also powerful information-collecting devices. The GPS chip can grab a satellite signal to learn your location, companies like Apple can glean data about larger movement trends during COVID, and the onboard accelerometer senses motion. But that accelerometer, a standard piece of hardware,...
Tue Aug 11, 2020 23:16
For detail work. (Louis Hansel via Unsplash/)Though it doesn’t get as much attention as larger chef’s knives, a great paring knife can be life-changing. Their size allows them to be nimble workhorses for peeling and dicing smaller fruits, vegetables, and herbs, and mincing garlic. They’re also essential for more intricate kitchen work, like de-seeding fruit, de-vining shrimp, or segmenting citrus fruits.We’ve picked some of our favorites.A timeless choice for any kitchen. (Amazon/)Made in Germany,...
Tue Aug 11, 2020 19:19
These slicers offer consistency and ease. (Wilhelm Gunkel via Unsplash/)Sometimes a knife just won’t cut it when it comes to getting thinly sliced produce. A mandoline can give you a slim, uniform sliver that will cook evenly every time. Many mandolines have extra features to customize your cuts, making them a great tool for creating appetizing meals that will look and taste great. Here are some fantastic options for your slicing needs; get ready to get cookin'.Master making potato chips. (Amazon/)This...
Tue Aug 11, 2020 19:16
Researchers found that simple multi-layered cloth masks and surgical masks work well enough to prevent the spread of the coronavirus. (Pixabay/)Until 2020, if your job or health didn’t require it, it’s likely that you never thought about wearing a protective face covering. Now, as the airborne coronavirus remains a threat in most of the world, how to wear a mask and which one is best are at the top of many people’s minds. According to a study out last week in Science Advances, there could be an easy...
Tue Aug 11, 2020 19:09
A second home for Fido. (Tomasz Filipek via Unsplash/)We know it’s never fun to put your pooch in their crate or cage, but it’s unavoidable at times. It’s super important to find a cage that is comfortable for your pup no matter their size, shape, or breed. Below are a few of the sturdiest cages we could find, so next time you can throw in a few of your good boy’s favorite toys or treats and rest assured that they are happy and out of harm’s way.Remarkably reliable. (Amazon/)This double-door crate...
Tue Aug 11, 2020 18:54
Fun flying in the sky. (Anna Kolosyuk via Unsplash/)Has there ever been a kite flying at the beach that wasn’t, to some degree, entertaining? You can take a kite along to a camping site or a picnic at the park, or on your winter holiday to a warmer destination. With the right design, material, and sturdiness to withstand high winds, quality kites will last for countless uses — and bring you the pleasure of amusing yourself with the sky. Below are some of the best kites that will leave you happily...
Tue Aug 11, 2020 15:41
Think about how many people you'll bump into, and how long you'll be in transit, before booking those tickets. (Pexels/)Summer is in full swing, and nobody would blame you if a trip to the beach or your favorite city is tempting you. But even if you are itching for a vacation outside of your living room, there’s a few things to consider—namely where you’re going and how exactly you’re going to get there.Travel advisories are changing constantly, not to mention how several countries have also issued...
Tue Aug 11, 2020 15:00
A survey on the attitudes of Chinese medical students towards current pathology education. BMC Med Educ. 2020 Aug 08;20(1):259 Authors: Xu C, Li Y, Chen P, Pan M, Bu X Abstract BACKGROUND: Pathology education provides information on pathology and guides students to become pathologists. Recently, the Ministry of Education of the People's Republic of China required the establishment of the system of 'High-quality Online and Offline Courses',...
Tue Aug 11, 2020 14:12
Learning to prescribe and instruct exercise in physiotherapy education through authentic continuous assessment and rubrics. BMC Med Educ. 2020 Aug 08;20(1):258 Authors: Chong DYK, Tam B, Yau SY, Wong AYL Abstract BACKGROUND: Authentic assessment and effective feedback are among various strategies that promote learning in the assessment process. These strategies are commonly used during clinical placements. However, they are rarely implemented...
Tue Aug 11, 2020 14:12
Suicidal behaviours among adolescents from 90 countries: a pooled analysis of the global school-based student health survey. BMC Public Health. 2020 Aug 10;20(1):1102 Authors: Campisi SC, Carducci B, Akseer N, Zasowski C, Szatmari P, Bhutta ZA Abstract BACKGROUND: Understanding the burden and determinants of suicide during adolescence is key to achieving global health goals. We examined the prevalence and determinants of self-reported suicidal...
Tue Aug 11, 2020 13:55
Introduction of multi-dose PCV 13 vaccine in Benin: from the decision to vaccinators experience. BMC Public Health. 2020 Aug 08;20(1):1216 Authors: Abdoulaye Alfa D, Houngnihin RA, Ilboudo GP, Dick N, Kaucley L, Essoh TA Abstract BACKGROUND: In 2011, Benin introduced the 13-valent pneumococcal conjugated vaccine (PCV13), in a single-dose vial, into its Expanded Programme for Immunisation (EPI) with support from Gavi. In April 2018, with the...
Tue Aug 11, 2020 13:55
Exposure to environmental tobacco smoke and prevalence of asthma among adolescents in a middle eastern country. BMC Public Health. 2020 Aug 08;20(1):1210 Authors: Booalayan H, Abdualrasool M, Al-Shanfari S, Boujarwa A, Al-Mukaimi A, Alkandery O, Akhtar S Abstract BACKGROUND: There is increasing evidence linking environmental tobacco smoke (ETS) exposure at homes to the development of asthma among adolescents. Few studies have addressed this...
Tue Aug 11, 2020 13:55
Work-related moderators of the relationship between organizational change and sickness absence: a longitudinal multilevel study. BMC Public Health. 2020 Aug 08;20(1):1218 Authors: Grønstad A, Kjekshus LE, Tjerbo T, Bernstrøm VH Abstract BACKGROUND: A sizeable body of research has demonstrated a relationship between organizational change and increased sickness absence. However, fewer studies have investigated what factors might mitigate this...
Tue Aug 11, 2020 13:55
Factors associated with diagnostic delay in recurrent TB. BMC Public Health. 2020 Aug 08;20(1):1207 Authors: Xie Z, Wang T, Chen H, Wang D, Gao X, Hui Y Abstract BACKGROUND: Recurrent tuberculosis (TB) contributes to the burden of TB. The study was designed to explore the time of diagnostic delay and risk of delay in patients with recurrent TB in China. METHODS: A total of 13,334 patients with new and recurrent TB registered in Yulin...
Tue Aug 11, 2020 13:55
Social inequalities, sexual tourism and HIV in Cartagena, Colombia: an ethnographic study. BMC Public Health. 2020 Aug 08;20(1):1208 Authors: Quevedo-Gómez MC, Krumeich A, Abadía-Barrero CE, van den Borne HW Abstract BACKGROUND: Cartagena, Colombia's main port on the Caribbean Coast, reported an HIV incidence of 7.5 per 100,000 inhabitants in 2007 with 90.0% transmission by heterosexual contact and 70 identified as women with a stable partner....
Tue Aug 11, 2020 13:55
Factors influencing the length of hospital stay during the intensive phase of multidrug-resistant tuberculosis treatment at Amhara regional state hospitals, Ethiopia: a retrospective follow up study. BMC Public Health. 2020 Aug 08;20(1):1217 Authors: Tamirat KS, Andargie G, Babel YA Abstract BACKGROUND: The length of hospital stay is the duration of hospitalization, which reflects disease severity and resource utilization indirectly. Generally,...
Tue Aug 11, 2020 13:55
What factors are associated with maternal undernutrition in eastern zone of Tigray, Ethiopia? Evidence for nutritional well-being of lactating mothers. BMC Public Health. 2020 Aug 08;20(1):1214 Authors: Abera SF, Kantelhardt EJ, Bezabih AM, Tsadik M, Lauvai J, Ejeta G, Wienke A, Frank J, Scherbaum V Abstract BACKGROUND: Maternal undernutrition is a pervasive health problem among Ethiopian mothers. This study aims at identifying the level of...
Tue Aug 11, 2020 13:55
Understanding the acceptability, barriers and facilitators for chlamydia and gonorrhoea screening in technical colleges: qualitative process evaluation of the "Test n Treat" trial. BMC Public Health. 2020 Aug 08;20(1):1212 Authors: Fleming C, Drennan VM, Kerry-Barnard S, Reid F, Adams EJ, Sadiq ST, Phillips R, Majewska W, Harding-Esch EM, Cousins EC, Yoward F, Oakeshott P Abstract BACKGROUND: Low uptake of sexually transmitted infection testing...
Tue Aug 11, 2020 13:55
E-cigarette environmental and fire/life safety risks in schools reported by secondary school teachers. BMC Public Health. 2020 Aug 08;20(1):1215 Authors: Fakeh Campbell ML, Sansone A, Gonzalez LN, Schroth KRJ, Shendell DG Abstract BACKGROUND: To identify if e-cigarette usage is an on-campus problem for secondary schools and evaluate initial school survey responses. More specifically, this survey can aid in identifying where students are seen...
Tue Aug 11, 2020 13:55
"Oh-oh, the others are standing up... I better do the same". Mixed-method evaluation of the implementation process of 'Take a Stand!' - a cluster randomized controlled trial of a multicomponent intervention to reduce sitting time among office workers. BMC Public Health. 2020 Aug 08;20(1):1209 Authors: Danquah IH, Kloster S, Tolstrup JS Abstract BACKGROUND: Multicomponent workplace-based interventions aimed at reducing sitting time among office...
Tue Aug 11, 2020 13:55
Demographic, behavioral, and cardiovascular disease risk factors in the Saudi population: results from the Prospective Urban Rural Epidemiology study (PURE-Saudi). BMC Public Health. 2020 Aug 08;20(1):1213 Authors: Alhabib KF, Batais MA, Almigbal TH, Alshamiri MQ, Altaradi H, Rangarajan S, Yusuf S Abstract BACKGROUND: Cardiovascular disease (CVD) is the major cause of death in Saudi Arabia. We aimed to assess associated demographic, behavioral,...
Tue Aug 11, 2020 13:55
Asthma control factors in the Gulf Cooperation Council (GCC) countries and the effectiveness of ICS/LABA fixed dose combinations: a dual rapid literature review. BMC Public Health. 2020 Aug 08;20(1):1211 Authors: Noibi S, Mohy A, Gouhar R, Shaker F, Lukic T, Al-Jahdali H Abstract BACKGROUND: Asthma control is influenced by multiple factors. These factors must be considered when appraising asthma interventions and their effectiveness in the...
Tue Aug 11, 2020 13:55
Rates and causes of mortality among children and young people with and without intellectual disabilities in Scotland: a record linkage cohort study of 796 190 school children. BMJ Open. 2020 Aug 09;10(8):e034077 Authors: Smith GS, Fleming M, Kinnear D, Henderson A, Pell JP, Melville C, Cooper SA Abstract OBJECTIVES: To investigate mortality rates and causes in children and young people with intellectual disabilities. DESIGN: Retrospective...
Tue Aug 11, 2020 15:34
Risk factors for pain and functional impairment in people with knee and hip osteoarthritis: a systematic review and meta-analysis. BMJ Open. 2020 Aug 07;10(8):e038720 Authors: Sandhar S, Smith TO, Toor K, Howe F, Sofat N Abstract OBJECTIVE: To identify risk factors for pain and functional deterioration in people with knee and hip osteoarthritis (OA) to form the basis of a future 'stratification tool' for OA development or progression. ...
Tue Aug 11, 2020 15:34
Associations between antenatal and perinatal risk factors and cerebral palsy: a Swedish cohort study. BMJ Open. 2020 Aug 07;10(8):e038453 Authors: Jöud A, Sehlstedt A, Källén K, Westbom L, Rylander L Abstract OBJECTIVES: To investigate known and suggested risk factors associated with cerebral palsy in a Swedish birth cohort, stratified by gestational age. SETTING: Information on all births between 1995 and 2014 in Skåne, the southernmost...
Tue Aug 11, 2020 15:34
Role of probiotics in patients with colorectal cancer: a systematic review protocol of randomised controlled trial studies. BMJ Open. 2020 Aug 07;10(8):e038128 Authors: Dikeocha IJ, Al-Kabsi AM, Hussin S, Alshawsh MA Abstract INTRODUCTION: Colorectal cancer is one of the leading causes of cancer-related morbidity worldwide and it has been reported to be associated with poor lifestyle habits which include excess tobacco and alcohol intake as...
Tue Aug 11, 2020 15:34
Potentially addictive drugs dispensing to patients receiving opioid agonist therapy: a register-based prospective cohort study in Norway and Sweden from 2015 to 2017. BMJ Open. 2020 Aug 07;10(8):e036860 Authors: Vold JH, Aas C, Skurtveit S, Odsbu I, Chalabianloo F, Reutfors J, Halmøy A, Johansson KA, Fadnes LT Abstract OBJECTIVES: To compare the use of benzodiazepines, z-hypnotics, gabapentinoids, opioids and centrally acting stimulants (CAS)...
Tue Aug 11, 2020 15:34
Generating national projections of dementia cases for Ireland using a calibrated macro-simulation model. BMJ Open. 2020 Aug 07;10(8):e035463 Authors: Pierse T, Keogh F, O'Neill S Abstract INTRODUCTION: Epidemiological data on dementia is not available in many European countries and regions due to the high cost and complexity of conducting large scale dementia screening studies. The available epidemiological studies identify potentially substantial...
Tue Aug 11, 2020 15:34
The cost of recreation: how hiking could be making birds sick. Conserv Physiol. 2020;8(1):coaa058 Authors: Allan BJM PMID: 32774858 [PubMed - as supplied by publisher]
Tue Aug 11, 2020 19:01
Comparing Methods from the National Cancer Institute vs Multiple Source Method for Estimating Usual Intake of Nutrients in the Hispanic Community Health Study/Study of Latino Youth. J Acad Nutr Diet. 2020 Aug 06;: Authors: Pereira JL, de Castro MA, Crispim SP, Fisberg RM, Isasi CR, Mossavar-Rahmani Y, Van Horn L, Carnethon MR, Daviglus ML, Perreira KM, Gallo LC, Sotres-Alvarez D, Mattei J Abstract BACKGROUND: The Multiple Source Method (MSM)...
Tue Aug 11, 2020 14:47
Molecular characteristics and physiological roles of Na+ -K+ -Cl- cotransporter 2. J Cell Physiol. 2020 Aug 10;: Authors: Marcoux AA, Tremblay LE, Slimani S, Fiola MJ, Mac-Way F, Garneau AP, Isenring P Abstract Na+ -K+ -Cl- cotransporter 2 (NKCC2; SLC12A1) is an integral membrane protein that comes as three splice variants and mediates the cotranslocation of Na+ , K+ , and Cl- ions through the apical membrane of the thick ascending loop of...
Tue Aug 11, 2020 16:00
MALAT1 recruited the E3 ubiquitin ligase FBXW7 to induce CRY2 ubiquitin-mediated degradation and participated in trophoblast migration and invasion. J Cell Physiol. 2020 Aug 10;: Authors: Wu L, Liu Q, Yin T, Fan C, Yi X, Cheng B Abstract This study aimed to investigate the mechanism by which MALAT1 regulates CRY2 expression and participates in trophoblast migration and invasion. Three patients with unexplained recurrent spontaneous abortion,...
Tue Aug 11, 2020 16:00
Cartilage regeneration with dual-drug-releasing injectable hydrogel/microparticle system: In vitro and in vivo study. J Cell Physiol. 2020 Aug 10;: Authors: Naghizadeh Z, Karkhaneh A, Nokhbatolfoghahaei H, Farzad-Mohajeri S, Rezai-Rad M, Dehghan MM, Aminishakib P, Khojasteh A Abstract In this study, we developed an injectable in situ forming hydrogel/microparticle system consisting of two drugs, melatonin and methylprednisolone, to investigate...
Tue Aug 11, 2020 16:00
IRE1α/NOX4 signaling pathway mediates ROS-dependent activation of hepatic stellate cells in NaAsO2 -induced liver fibrosis. J Cell Physiol. 2020 Aug 10;: Authors: Tao Y, Qiu T, Yao X, Jiang L, Wang N, Jiang J, Jia X, Wei S, Zhang J, Zhu Y, Tian W, Yang G, Liu X, Liu S, Ding Y, Sun X Abstract Liver fibrosis is a severe health problem worldwide, and it is characterized by the activation of hepatic stellate cells (HSCs) and excessive deposition...
Tue Aug 11, 2020 16:00
Structure-activity relationships for osmium(II) arene phenylazopyridine anticancer complexes functionalised with alkoxy and glycolic substituents. J Inorg Biochem. 2020 Jun 24;210:111154 Authors: Needham RJ, Bridgewater HE, Romero-Canelón I, Habtemariam A, Clarkson GJ, Sadler PJ Abstract Twenty-four novel organometallic osmium(II) phenylazopyridine (AZPY) complexes have been synthesised and characterised; [Os(η6-arene)(5-RO-AZPY)X]Y, where...
Tue Aug 11, 2020 13:50
Umbilical vein infusion of Prostaglandin I2 increases ductus venosus shunting of oxygen rich blood but does not increase cerebral oxygen delivery in the fetal sheep. J Physiol. 2020 Aug 10;: Authors: Darby JRT, Schrauben EM, Saini BS, Holman SL, Perumal SR, Seed M, Macgowan CK, Morrison JL Abstract KEY POINTS: The ductus venosus (DV) is a dynamic fetal shunt that allows substrate rich blood from the umbilical vein to bypass the hepatic circulation....
Tue Aug 11, 2020 15:26
High-fat versus high-carbohydrate diets for optimal higher intensity endurance exercise performance: and the winner is…. J Physiol. 2020 Aug 10;: Authors: Melby CL PMID: 32776510 [PubMed - as supplied by publisher]
Tue Aug 11, 2020 15:26
Πολλές φορές η θεραπεία μίας νόσου έχει να κάνει περισσότερο με το μυαλό παρά με το σώμα. Για την ακρίβεια, εκτενείς καταγραφές δείχνουν ότι οι άνθρωποι συχνά αισθάνονται καλύτερα μετά τη λήψη θεραπείας χωρίς ενεργά συστατικά -τα γνωστά εικονικά φάρμακα ή placebo- απλώς επειδή πιστεύουν ότι είναι πραγματική. Ομάδα ερευνητών από το Πανεπιστήμιο του Michigan και το Κολέγιο Darmouth είναι η πρώτη που δείχνει ότι τα εικονικά φάρμακα μειώνουν τους δείκτες στον εγκέφαλο που υποδηλώνουν την συναισθηματική...
Tue Aug 11, 2020 12:25
Τα παιδιά, των οποίων οι έγκυες μητέρες έκαναν χρήσης κάνναβης, αντιμετωπίζουν σημαντικά μεγαλύτερο -κατά 50%- κίνδυνο αυτισμού, σύμφωνα με μία νέα καναδική επιστημονική έρευνα, τη μεγαλύτερη του είδους της μέχρι σήμερα. Οι ερευνητές, με επικεφαλής τον καθηγητή Μαιευτικής-Γυναικολογίας Μαρκ Γουόκερ του πανεπιστημίου και του νοσοκομείου της Οτάβα, οι οποίοι έκαναν τη σχετική δημοσίευση στο Nature Medicine, ανέλυσαν στοιχεία για περίπου μισό εκατομμύριο εγκύους, από τις οποίες περίπου οι 3.000 (ποσοστό...
Tue Aug 11, 2020 10:39
Η βακτηριακή κολπίτιδα είναι μια μόλυνση που επηρεάζει περισσότερο από το 20% των γυναικών παγκοσμίως. Προκαλείται από μεταβολή στη φυσική ισορροπία του μικροβιώματος του κόλπου και οδηγεί σε ανεπιθύμητες παρενέργειες στην εγκυμοσύνη, καθώς και σε μεγαλύτερη ευαισθησία σε σεξουαλικώς μεταδιδόμενα νοσήματα, όπως ο ιός HIV, ο ιός του έρπητα, τα χλαμύδια ή η γονόρροια. Και παρόλο που προηγούμενες μελέτες υποστηρίζουν σθεναρά ότι τα μικροβιώματα των συντρόφων μπορεί να «ανταλλάσσεται» στην βακτηριακή...
Tue Aug 11, 2020 10:10
Σε μία από τις μεγαλύτερης κλίμακας έρευνες που έχουν διεξαχθεί για τη συσχέτιση μεταξύ σωματικού βάρους και εγκεφαλικής δυσλειτουργίας, οι ερευνητές των κορυφαίων κλινικών ψυχικής υγείας Amen Clinics διαπίστωσαν ανησυχητικά αυξημένο κίνδυνο εκδήλωσης Νόσου Αλτσχάιμερ και άλλων γνωστικών και ψυχιατρικών διαταραχών εξαιτίας υπερβολικού βάρους και παχυσαρκίας. Για τις ανάγκες της μελέτης, που δημοσιεύεται στην Journal of Alzheimer’s Disease, οι επιστήμονες ανέλυσαν πάνω από 35.000 λειτουργικές νευροαπεικονιστικές...
Tue Aug 11, 2020 08:55
Ένα πρώιμο τεστ αίματος μπορεί να ανιχνεύσει ποια μωρά που υφίστανται υποξία (ανεπαρκή οξυγόνωση) κατά τη γέννησή τους διατρέχουν κίνδυνο σοβαρών νευροδιαταραχών, όπως εγκεφαλική παράλυση και επιληψία. Το πρωτότυπο τεστ, που δημιουργήθηκε υπό την καθοδήγηση ερευνητών από το Imperial College του Λονδίνου, εντοπίζει συγκεκριμένα γονίδια που έχουν ενεργοποιηθεί και απενεργοποιηθεί και τα οποία συνδέονται με μακροχρόνια νευρολογικά προβλήματα. Η έρευνα, που δημοσιεύθηκε στο Scientific Reports, πραγματοποιήθηκε...
Tue Aug 11, 2020 08:50
Τα ευρήματα μιας τυχαιοποιημένης ελεγχόμενης μελέτης περί τη διατροφή από Πανεπιστήμιο Penn State, έδειξαν πως η προσθήκη έξι γραμμαρίων ενός συγκεκριμένου μείγματος μπαχαρικών σε γεύματα πλούσια σε λιπαρά και υδατάνθρακες, μείωσε τη φλεγμονή των συμμετεχόντων συγκριτικά με τα γεύματα περιορισμένης ή μηδενικής προσθήκης μπαχαρικών. Σύμφωνα με την επικεφαλής της μελέτης, τα ευρήματα έρχονται να προστεθούν σε σειρά επιστημονικών συμπερασμάτων που αναδεικνύουν τη συμβολή πλήθους μπαχαρικών στην καλή...
Tue Aug 11, 2020 08:40
Μια ομάδα ερευνητών από το Ινστιτούτο Biozentrum του Πανεπιστημίου του Basel, ανακάλυψε μια νέα σύνδεση ανάμεσα σε μία γενετική μετάλλαξη και τις κοινωνικές δυσκολίες που σχετίζονται με τον αυτισμό. Πιο συγκεκριμένα, η σχετική μελέτη που δημοσιεύθηκε στο Nature αναφέρει πως η μετάλλαξη στο γονίδιο νευρολιγίνη 3 μειώνει την επίδραση της ορμόνης ωκυτοκίνη, με την ερευνητική ομάδα να παρουσιάζει μια θεραπευτική προσέγγιση που θα μπορούσε να ομαλοποιήσει την κοινωνική συμπεριφορά στον αυτισμό. Οι επιστήμονες...
Tue Aug 11, 2020 08:20
Το Κέντρο Ιατρικής Ακριβείας με έδρα το Πανεπιστήμιο της Νότιας Αυστραλίας ηγήθηκε μίας μελέτης, η οποία δημοσιεύθηκε στο Eclinical Medicine και συνδέει το βαρύ κάπνισμα με 28 διαφορετικές καταστάσεις υγείας, αποκαλύπτοντας 17πλάσια αύξηση στα περιστατικά εμφυσήματος, 8πλάσια αύξηση στην αθηροσκλήρωση και 6,5 φορές περισσότερα περιστατικά καρκίνου του πνεύμονα. Οι επιστήμονες ανέλυσαν νοσοκομειακά δεδομένα και στατιστικά θνησιμότητας από περισσότερους από 152.483 καπνιστές στη βρετανική Βιοτράπεζα...
Tue Aug 11, 2020 08:05
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