Pharmaceuticals, Vol. 13, Pages 190: Reversal of Increase in Intestinal Permeability by Mangifera indica Seed Kernel Extract in High-Fat Diet-Induced Obese Mice Pharmaceuticals doi: 10.3390/ph13080190 Authors: Pavan Kumar Mujawdiya Pravesh Sharma Shashwat Sharad Suman Kapur Obesity and hyper-intestinal permeability are interconnected. This study is designed to evaluate the ability of Mangifera indica seed kernel extract (MESK) in restoring the intestinal barrier and preventing...
Tue Aug 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 760: Progestogens Are Metabolized by the Gut Microbiota: Implications for Colonic Drug Delivery Pharmaceutics doi: 10.3390/pharmaceutics12080760 Authors: Zoe Coombes Vipul Yadav Laura E. McCoubrey Cristina Freire Abdul W. Basit R. Steven Conlan Deyarina Gonzalez Following oral administration, the bioavailability of progestogens is very low and highly variable, in part due to metabolism by cytochrome P450 enzymes found in the mucosa of the...
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Pharmaceutics, Vol. 12, Pages 759: Synthetic Virus-Derived Nanosystems (SVNs) for Delivery and Precision Docking of Large Multifunctional DNA Circuitry in Mammalian Cells Pharmaceutics doi: 10.3390/pharmaceutics12080759 Authors: Francesco Aulicino Julien Capin Imre Berger DNA delivery is at the forefront of current research efforts in gene therapy and synthetic biology. Viral vectors have traditionally dominated the field; however, nonviral delivery systems are increasingly gaining...
Tue Aug 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 756: Mitochondrion-Directed Nanoparticles Loaded with a Natural Compound and a microRNA for Promoting Cancer Cell Death via the Modulation of Tumor Metabolism and Mitochondrial Dynamics Pharmaceutics doi: 10.3390/pharmaceutics12080756 Authors: Yu-Li Lo Chen-Shen Wang Yen-Chun Chen Tse-Yuan Wang Yih-Hsin Chang Chun-Jung Chen Ching-Ping Yang Mitochondrial dysfunction may cause cancer and metabolic syndrome. Ellagic acid (abbreviated as E),...
Tue Aug 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 754: Development of Mannose-Modified Carboxylated Curdlan-Coated Liposomes for Antigen Presenting Cell Targeted Antigen Delivery Pharmaceutics doi: 10.3390/pharmaceutics12080754 Authors: Eiji Yuba Yoshiki Fukaya Shin Yanagihara Nozomi Kasho Atsushi Harada Specific delivery to antigen presenting cells (APC) and precise control of the intracellular fate of antigens are crucial to induce cellular immunity that directly and specifically attacks cancer...
Tue Aug 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 757: Preparation of Hot-Melt Extruded Dosage Form for Enhancing Drugs Absorption Based on Computational Simulation Pharmaceutics doi: 10.3390/pharmaceutics12080757 Authors: Sung-Min Choi Sung-Hoon Lee Chin-Yang Kang Jun-Bom Park The aim of this study was to control the dissolution rate and permeability of cilostazol. To enhance the dissolution rate of the active pharmaceutical ingredient (API), hot-melt extrusion (HME) technology was applied to...
Tue Aug 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 755: Prediction of Drug-Induced Hyperbilirubinemia by In Vitro Testing
Pharmaceutics, Vol. 12, Pages 755: Prediction of Drug-Induced Hyperbilirubinemia by In Vitro Testing Pharmaceutics doi: 10.3390/pharmaceutics12080755 Authors: Péter Tátrai Péter Krajcsi Bilirubin, the end product of heme catabolism, is produced continuously in the body and may reach toxic levels if accumulates in the serum and tissues; therefore, a highly efficient mechanism evolved for its disposition. Normally, unconjugated bilirubin enters hepatocytes through the uptake transporters...
Tue Aug 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 758: Like a Rolling Stone: Sting-Cgas Pathway and Cell-Free DNA as Biomarkers for Combinatorial Immunotherapy Pharmaceutics doi: 10.3390/pharmaceutics12080758 Authors: Sicard Fina Fanciullino Barlesi Ciccolini Combining immune checkpoint inhibitors with other treatments likely to harness tumor immunity is a rising strategy in oncology. The exact modalities of such a combinatorial regimen are yet to be defined, and most attempts have relied...
Tue Aug 11, 2020 03:00
Pharmaceutics, Vol. 12, Pages 753: Controlled Catheter Movement Affects Dye Dispersal Volume in Agarose Gel Brain Phantoms Pharmaceutics doi: 10.3390/pharmaceutics12080753 Authors: Jason N. Mehta Gabrielle R. McRoberts Christopher G. Rylander The standard of care for treatment of glioblastoma results in a mean survival of only 12 to 15 months. Convection-enhanced delivery (CED) is an investigational therapy to treat glioblastoma that utilizes locoregional drug delivery via a small-caliber...
Tue Aug 11, 2020 03:00
Pharmacy, Vol. 8, Pages 142: Developing Physical Assessment Skills in Pharmacy Students through Participation in a Creative Movement Workshop: An Interdisciplinary Study between Pharmacy and Dance Pharmacy doi: 10.3390/pharmacy8030142 Authors: Amber Wesner Ting-Yu Chen The role a pharmacist plays in the care of patients is continually changing and expanding. Most recently, there is movement towards including pharmacists in the physical assessment of patients. We developed a creative...
Tue Aug 11, 2020 03:00
Plants, Vol. 9, Pages 1015: Predicting the Suitable Geographical Distribution of Sinadoxa Corydalifolia under Different Climate Change Scenarios in the Three-River Region Using the MaxEnt Model Plants doi: 10.3390/plants9081015 Authors: Xiaotao Huang Li Ma Chunbo Chen Huakun Zhou Buqing Yao Zhen Ma Sinadoxa corydalifolia is a perennial grass with considerable academic value as a rare species owing to habitat destruction and a narrow distribution. However, its distribution...
Tue Aug 11, 2020 03:00
Plants, Vol. 9, Pages 1014: Genome-Wide Analysis Reveals Transcription Factors Regulated by Spider-Mite Feeding in Cucumber (Cucumis sativus) Plants doi: 10.3390/plants9081014 Authors: Jun He Harro J. Bouwmeester Marcel Dicke Iris F. Kappers To gain insight into the regulatory networks that underlie the induced defense in cucumber against spider mites, genes encoding transcription factors (TFs) were identified in the cucumber (Cucumissativus) genome and their regulation by two-spotted...
Tue Aug 11, 2020 03:00
Plants, Vol. 9, Pages 1013: A New Active Substance Derived from Lyzed Willaertia magna C2c Maky Cells to Fight Grapevine Downy Mildew Plants doi: 10.3390/plants9081013 Authors: Sandrine Demanèche Laurène Mirabel Olivier Abbe Jean-Baptiste Eberst Jean-Luc Souche Downy mildew of grapevine is one of the most destructive grapevine diseases worldwide. Nowadays, downy mildew control relies almost exclusively on the use of chemical pesticides, including copper products, which are...
Tue Aug 11, 2020 03:00
Plants, Vol. 9, Pages 1011: Exploiting Biological Nitrogen Fixation: A Route Towards a Sustainable Agriculture Plants doi: 10.3390/plants9081011 Authors: Abdoulaye Soumare Abdala G. Diedhiou Moses Thuita Mohamed Hafidi Yedir Ouhdouch Subramaniam Gopalakrishnan Lamfeddal Kouisni For all living organisms, nitrogen is an essential element, while being the most limiting in ecosystems and for crop production. Despite the significant contribution of synthetic fertilizers,...
Tue Aug 11, 2020 03:00
Plants, Vol. 9, Pages 1012: Exploring the Use of Bryophyllum as Natural Source of Bioactive Compounds with Antioxidant Activity to Prevent Lipid Oxidation of Fish Oil-In-Water Emulsions Plants doi: 10.3390/plants9081012 Authors: Pascual García-Pérez Sonia Losada-Barreiro Carlos Bravo-Díaz Pedro P. Gallego The current industrial requirements for food naturalness are forcing the development of new strategies to achieve the production of healthier foods by replacing the use of...
Tue Aug 11, 2020 03:00
Sci, Vol. 2, Pages 63: Coronavirus Disease (COVID-19): Handling Challenges in Kuwait Sci doi: 10.3390/sci2030063 Authors: Janvier Gasana Maryam Shehab The world is currently facing a serious pandemic of coronavirus disease 2019 (COVID-19) which started in Wuhan, China, and was then transmitted rapidly to other countries. Countries applied different methods and procedures in an attempt to prevent or reduce and/or control the incidence of cases and manage existing ones. This paper discusses...
Tue Aug 11, 2020 03:00
Social Sciences, Vol. 9, Pages 141: Giving Guys Get the Girls: Men Appear More Desirable to the Opposite Sex When Displaying Costly Donations to the Homeless Social Sciences doi: 10.3390/socsci9080141 Authors: Wendy Iredale Keli Jenner Mark Van Vugt Tammy Dempster One of the evolutionary adaptive benefits of altruism may be that it acts as an honest (reliable) signal of men’s mate quality. In this study, 285 female participants were shown one of three video scenarios...
Tue Aug 11, 2020 03:00
Societies, Vol. 10, Pages 60: Preservation without Representation: Making CLG Programs Vehicles for Inclusive Leadership, Historic Preservation, and Engagement Societies doi: 10.3390/soc10030060 Authors: Andrea R. Roberts This article examines public historic preservation agencies’ ability to support social inclusion aims within the context of the Certified Local Government (CLG) program. Though administered by the Texas Historical Commission, Texas’ State CLG program...
Tue Aug 11, 2020 03:00
Sports, Vol. 8, Pages 113: Post-Exercise Sweat Loss Estimation Accuracy of Athletes and Physically Active Adults: A Review Sports doi: 10.3390/sports8080113 Authors: Eric O’Neal Tara Boy Brett Davis Kelly Pritchett Robert Pritchett Svetlana Nepocatych Katherine Black The main purposes of this review were to provide a qualitative description of nine investigations in which sweat losses were estimated by participants following exercise and to perform a quantitative analysis...
Tue Aug 11, 2020 03:00
Sports, Vol. 8, Pages 112: The Relationship between CrossFit® Performance and Laboratory-Based Measurements of Fitness Sports doi: 10.3390/sports8080112 Authors: Elisabeth K. Zeitz Lena F. Cook Joshua D. Dexheimer Srdjan Lemez Whitney D. Leyva Immanuel Y. Terbio Justin R. Tran Edward Jo To date, research has examined the physiological determinants of performance in standardized CrossFit® (CF) workouts but not without the influence of CF familiarity. Therefore,...
Tue Aug 11, 2020 03:00
Technologies, Vol. 8, Pages 44: Waiter Robots Conveying Drinks Technologies doi: 10.3390/technologies8030044 Authors: Ash Yaw Sang Wan Yi De Soong Edwin Foo Wai Leong Eugene Wong Wai Shing Michael Lau Robots have been reportedly seen serving food in several restaurants in many parts of the world. New ventures have been deploying mechanical partners which promote the growth in service robotics. However, robots are considerably incompetent when it comes to beverage and soup...
Tue Aug 11, 2020 03:00
Toxics, Vol. 8, Pages 55: Effects of MP Polyethylene Microparticles on Microbiome and Inflammatory Response of Larval Zebrafish Toxics doi: 10.3390/toxics8030055 Authors: Nicholas Kurchaba Bryan J. Cassone Caleb Northam Bernadette F. Ardelli Christophe M. R. LeMoine Plastic polymers have quickly become one of the most abundant materials on Earth due to their low production cost and high versatility. Unfortunately, some of the discarded plastic can make its way into the environment...
Tue Aug 11, 2020 03:00
Toxins, Vol. 12, Pages 515: The Influence of NaCl and Glucose Content on Growth and Ochratoxin A Production by Aspergillus ochraceus, Aspergillus carbonarius and Penicillium nordicum Toxins doi: 10.3390/toxins12080515 Authors: Yan Wang Hao Yan Jing Neng Jian Gao Bolei Yang Yang Liu Ochratoxin A (OTA) is a nephrotoxic mycotoxin, which deserves particular attention for its widespread contamination of a variety of food and feed. Aspergillus ochraceus, Aspergillus carbonarius,...
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Toxins, Vol. 12, Pages 514: The Tripartite Interaction of Host Immunity–Bacillus thuringiensis Infection–Gut Microbiota Toxins doi: 10.3390/toxins12080514 Authors: Shuzhong Li Surajit De Mandal Xiaoxia Xu Fengliang Jin Bacillus thuringiensis (Bt) is an important cosmopolitan bacterial entomopathogen, which produces various protein toxins that have been expressed in transgenic crops. The evolved molecular interaction between the insect immune system and gut microbiota is changed...
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Toxins, Vol. 12, Pages 513: Occupational Exposure to Mycotoxins—Different Sampling Strategies Telling a Common Story Regarding Occupational Studies Performed in Portugal (2012–2020) Toxins doi: 10.3390/toxins12080513 Authors: Susana Viegas Carla Viegas Carla Martins Ricardo Assunção In occupational settings where exposure to organic dust occurs (e.g., intensive animal production, waste management, farming and many others) workers can also be exposed to mycotoxins. However, recognizing...
Tue Aug 11, 2020 03:00
TropicalMed, Vol. 5, Pages 130: Controlling Human Rabies: The Development of an Effective, Inexpensive and Locally Made Passive Cooling Device for Storing Thermotolerant Animal Rabies Vaccines Tropical Medicine and Infectious Disease doi: 10.3390/tropicalmed5030130 Authors: Ahmed Lugelo Katie Hampson Machunde Bigambo Rudovick Kazwala Felix Lankester Thermotolerant vaccines greatly improved the reach and impact of large-scale vaccination programs to eliminate diseases such...
Tue Aug 11, 2020 03:00
Vaccines, Vol. 8, Pages 450: Assessing the Immune Response of Atlantic Salmon (Salmo salar) after the Oral Intake of Alginate-Encapsulated Piscirickettsia salmonis Antigens Vaccines doi: 10.3390/vaccines8030450 Authors: Daniela Sotomayor-Gerding José Miguel Troncoso Alejandro Pino Felipe Almendras Mónica Rubilar Diaz Salmon rickettsial septicaemia (SRS) is the infectious disease that produces the highest losses in the Chilean salmon industry. As a new strategy for the control...
Tue Aug 11, 2020 03:00
Viruses, Vol. 12, Pages 879: Tomato Brown Rugose Fruit Virus Contributes to Enhanced Pepino Mosaic Virus Titers in Tomato Plants Viruses doi: 10.3390/v12080879 Authors: Chen Klap Neta Luria Elisheva Smith Lior Hadad Elena Bakelman Noa Sela Eduard Belausov Oded Lachman Diana Leibman Aviv Dombrovsky The tobamovirus tomato brown rugose fruit virus (ToBRFV), a major threat to tomato production worldwide, has recently been documented in mixed infections with the...
Tue Aug 11, 2020 03:00
Viruses, Vol. 12, Pages 877: Genetic and Antigenic Characterization and Retrospective Surveillance of Bovine Influenza D Viruses Identified in Hokkaido, Japan from 2018 to 2020 Viruses doi: 10.3390/v12080877 Authors: Jun Hayakawa Tomomi Masuko Tae Takehana Tohru Suzuki Influenza D virus (IDV), which is a new member of the Orthomyxoviridae family, is potentially involved in bovine respiratory diseases (BRDs). Bovine IDVs (BIDVs) from Japan have been distributed nationwide since...
Tue Aug 11, 2020 03:00
Viruses, Vol. 12, Pages 878: Structural Insights into Lactococcal Siphophage p2 Baseplate Activation Mechanism Viruses doi: 10.3390/v12080878 Authors: Silvia Spinelli Denise Tremblay Sylvain Moineau Christian Cambillau Adeline Goulet Virulent phages infecting L. lactis, an industry-relevant bacterium, pose a significant risk to the quality of the fermented milk products. Phages of the Skunavirus genus are by far the most isolated lactococcal phages in the cheese environments...
Tue Aug 11, 2020 03:00
Viruses, Vol. 12, Pages 876: Gammaherpesvirus in Cervid Species from Norway: Characterization of a New Virus in Wild and Semi-Domesticated Eurasian Tundra Reindeer (Rangifer tarandus tarandus) Viruses doi: 10.3390/v12080876 Authors: Carlos G. das Neves Carlos Sacristán Knut Madslien Morten Tryland Gammaherpesvirus infections have been described in cervids worldwide, mainly the genera Macavirus or Rhadinovirus. However, little is known about the gammaherpesviruses species infecting...
Tue Aug 11, 2020 03:00
Water, Vol. 12, Pages 2260: Problems and Countermeasures of River Management in the Process of Rapid Urbanization in China Water doi: 10.3390/w12082260 Authors: Ziyang Zhao Hongrui Wang Yuanyuan Zhang Caiyun Deng Qiong Xie Cheng Wang The rapid process of urbanization has led to water pollution, reduction of space areas and channel deposition. However, current river protection and management levels are not suitable for city development level and human demand. Therefore,...
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Water, Vol. 12, Pages 2259: Integrating Reservoir Operations and Flood Modeling with HEC-RAS 2D Water doi: 10.3390/w12082259 Authors: Matthew Garcia Andrew Juan Philip Bedient Current free to use models developed by the United States Army Corps of Engineers (USACE) perform unique functions (e.g., hydrology, hydraulics, reservoir operations, and flood impact analysis) that are widely used in numerous studies and applications. These models are commonly set up in a framework that...
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Water, Vol. 12, Pages 2258: Global River Monitoring Using Semantic Fusion Networks Water doi: 10.3390/w12082258 Authors: Zhihao Wei Kebin Jia Xiaowei Jia Ankush Khandelwal Vipin Kumar Global river monitoring is an important mission within the remote sensing society. One of the main challenges faced by this mission is generating an accurate water mask from remote sensing images (RSI) of rivers (RSIR), especially on a global scale with various river features. Aiming at better...
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Water, Vol. 12, Pages 2257: Electricity Generation, Salt and Nitrogen Removal and Microbial Community in Aircathode Microbial Desalination Cell for Saline-Alkaline Soil-Washing Water Treatment Water doi: 10.3390/w12082257 Authors: Chenglong Xu Jialei Lu Zhimiao Zhao Yinjiang Zhang Jiawei Zhang An aircathode microbial desalination cell (AMDC) was successfully started by inoculating anaerobic sludge into the anode of a microbial desalination cell and then used to study the...
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Water, Vol. 12, Pages 2256: The Role of Snowmelt on the Spatio-Temporal Variability of Spring Recharge in a Dolomitic Mountain Group, Italian Alps Water doi: 10.3390/w12082256 Authors: Lucianetti Giorgia Daniele Penna Lucia Mastrorillo Roberto Mazza Springs play a key role in the hydrology of mountain catchments and their water supply has a considerable impact on regional livelihood, biodiversity, tourism, and power generation. However, there is still limited knowledge of how...
Tue Aug 11, 2020 03:00
Water, Vol. 12, Pages 2255: Impact of Geology on Seasonal Hydrological Predictability in Alpine Regions by a Sensitivity Analysis Framework Water doi: 10.3390/w12082255 Authors: Maria Stergiadi Nicola Di Marco Diego Avesani Maurizio Righetti Marco Borga Catchment geology has a major influence on the relative impact of the main seasonal hydrological predictability sources (initial conditions (IC), climate forcing (CF)) on the forecast skill as it defines the system’s...
Tue Aug 11, 2020 03:00
Water, Vol. 12, Pages 2254: Physical Modelling of Arctic Coastlines—Progress and Limitations Water doi: 10.3390/w12082254 Authors: Sophia Korte Rebekka Gieschen Jacob Stolle Nils Goseberg Permafrost coastlines represent a large portion of the world’s coastal area and these areas have become increasingly vulnerable in the face of climate change. The predominant mechanism of coastal erosion in these areas has been identified through several observational studies as thermomechanical...
Tue Aug 11, 2020 03:00
Water, Vol. 12, Pages 2253: Determination of Actual Evapotranspiration and Crop Coefficients of California Date Palms Using the Residual of Energy Balance Approach Water doi: 10.3390/w12082253 Authors: Aliasghar Montazar Robert Krueger Dennis Corwin Alireza Pourreza Cayle Little Sonia Rios Richard L. Snyder As water scarcity becomes of greater concern in arid and semi-arid regions due to altered weather patterns, greater and more accurate knowledge regarding evapotranspiration...
Tue Aug 11, 2020 03:00
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