Antibiotics, Vol. 9, Pages 515: A Trypsin Inhibitor from Moringa oleifera Flowers Modulates the Immune Response In Vitro of Trypanosoma cruzi-Infected Human Cells Antibiotics doi: 10.3390/antibiotics9080515 Authors: Isabella Coimbra Vila Nova Leyllane Rafael Moreira Diego José Lira Torres Kamila Kássia dos Santos Oliveira Leydianne Leite de Siqueira Patriota Luana Cassandra Breitenbach Barroso Coelho Patrícia Maria Guedes Paiva Thiago Henrique Napoleão Virgínia Maria...
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Antibiotics, Vol. 9, Pages 509: The Bristol Sponge Microbiome Collection: A Unique Repository of Deep-Sea Microorganisms and Associated Natural Products Antibiotics doi: 10.3390/antibiotics9080509 Authors: Sam E. Williams Henry L. Stennett Catherine R. Back Kavita Tiwari Jorge Ojeda Gomez Martin R. Challand Katharine R. Hendry James Spencer Angela E. Essex-Lopresti Christine L. Willis Paul Curnow Paul R. Race The deep ocean is the largest habitat for...
Thu Aug 13, 2020 03:00
Antibiotics, Vol. 9, Pages 514: Clinical and Economic Burden of Carbapenem-Resistant Infection or Colonization Caused by Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter baumannii: A Multicenter Study in China Antibiotics doi: 10.3390/antibiotics9080514 Authors: Xuemei Zhen Cecilia Stålsby Lundborg Xueshan Sun Shuyan Gu Hengjin Dong Background: Carbapenem resistant Klebsiella pneumoniae (CRKP), Pseudomonas aeruginosa (CRPA), and Acinetobacter baumannii (CRAB)...
Thu Aug 13, 2020 03:00
Antibiotics, Vol. 9, Pages 512: Content and Mechanism of Action of National Antimicrobial Stewardship Interventions on Management of Respiratory Tract Infections in Primary and Community Care Antibiotics doi: 10.3390/antibiotics9080512 Authors: Lou Atkins Tim Chadborn Paulina Bondaronek Diane Ashiru-Oredope Elizabeth Beech Natalie Herd Victoria de La Morinière Marta González-Iraizoz Susan Hopkins Cliodna McNulty Anna Sallis A major modifiable factor contributing...
Thu Aug 13, 2020 03:00
Antibiotics, Vol. 9, Pages 511: Effective Treatment for Uncomplicated Urinary Tract Infections with Oral Fosfomycin, Single Center Four Year Retrospective Study Antibiotics doi: 10.3390/antibiotics9080511 Authors: Miroslav Fajfr Michal Balik Eva Cermakova Pavel Bostik Fosfomycin represents a relatively old antibiotic, but it is experiencing a comeback in recent years. According to some studies, the increasing therapeutic use of this drug led to a rapid increase in the levels...
Thu Aug 13, 2020 03:00
Antibiotics, Vol. 9, Pages 510: The Ascidian-Derived Metabolites with Antimicrobial Properties Antibiotics doi: 10.3390/antibiotics9080510 Authors: Marcello Casertano Marialuisa Menna Concetta Imperatore Among the sub-phylum of Tunicate, ascidians represent the most abundant class of marine invertebrates, with 3000 species by heterogeneous habitat, that is, from shallow water to deep sea, already reported. The chemistry of these sessile filter-feeding organisms is an attractive...
Thu Aug 13, 2020 03:00
Antibiotics, Vol. 9, Pages 513: Evaluation of Antioxidant, Antimicrobial and Tyrosinase Inhibitory Activities of Extracts from Tricholosporum goniospermum, an Edible Wild Mushroom Antibiotics doi: 10.3390/antibiotics9080513 Authors: Paola Angelini Roberto Venanzoni Giancarlo Angeles Flores Bruno Tirillini Giustino Orlando Lucia Recinella Annalisa Chiavaroli Luigi Brunetti Sheila Leone Simonetta Cristina Di Simone Maria Chiara Ciferri Gokhan Zengin Gunes...
Thu Aug 13, 2020 03:00
Antioxidants, Vol. 9, Pages 747: Oxidative Stress—Part of the Solution or Part of the Problem in the Hypoxic Environment of a Brain Tumor Antioxidants doi: 10.3390/antiox9080747 Authors: Kamil Krawczynski Jakub Godlewski Agnieszka Bronisz Rapid growth of brain tumors such as glioblastoma often results in oxygen deprivation and the emergence of hypoxic zones. In consequence, the enrichment of reactive oxygen species occurs, harming nonmalignant cells and leading them toward apoptotic...
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Antioxidants, Vol. 9, Pages 746: Germination Improves the Polyphenolic Profile and Functional Value of Mung Bean (Vigna radiata L.) Antioxidants doi: 10.3390/antiox9080746 Authors: Garyfallia Kapravelou Rosario Martínez Gloria Perazzoli Cristina Sánchez González Juan Llopis Samuel Cantarero Marie Goua Giovanna Bermano Jose Prados Consolación Melguizo Pilar Aranda María López-Jurado Jesus M. Porres The use of legumes as functional foods has gained increasing...
Thu Aug 13, 2020 03:00
Antioxidants, Vol. 9, Pages 744: Gd-Complex of a Rosmarinic Acid Conjugate as an Anti-Inflammatory Theranostic Agent via Reactive Oxygen Species Scavenging Antioxidants doi: 10.3390/antiox9080744 Authors: Hee-Kyung Kim Seonghwan Hwang Bokyung Sung Yeoun-Hee Kim Yongmin Chang Rosmarinic acid (RosA), an important polyphenol, is known for its antioxidant and anti-inflammatory activities. However, its application in theranostics has been rarely reported. Therefore, a new single-molecule...
Thu Aug 13, 2020 03:00
Antioxidants, Vol. 9, Pages 745: Protective Effect of Low Molecular Weight Peptides from Solenocera crassicornis Head against Cyclophosphamide-Induced Nephrotoxicity in Mice via the Keap1/Nrf2 Pathway Antioxidants doi: 10.3390/antiox9080745 Authors: Jiang Zhang Huang Yang Yu Tang Ding The major component of the Solenocera crassicornis head protein hydrolysates-fraction 1 (SCHPs-F1) are low molecular weight peptides (MW < 1 kDa). In this study, we investigated...
Thu Aug 13, 2020 03:00
Antioxidants, Vol. 9, Pages 743: ROS Generation in Microglia: Understanding Oxidative Stress and Inflammation in Neurodegenerative Disease Antioxidants doi: 10.3390/antiox9080743 Authors: Dominic S. A. Simpson Peter L. Oliver Neurodegenerative disorders, such as Alzheimer’s disease, are a global public health burden with poorly understood aetiology. Neuroinflammation and oxidative stress (OS) are undoubtedly hallmarks of neurodegeneration, contributing to disease progression....
Thu Aug 13, 2020 03:00
Atmosphere, Vol. 11, Pages 859: Validation of Satellite and Merged Rainfall Data over Ghana, West Africa Atmosphere doi: 10.3390/atmos11080859 Authors: Winifred Ayinpogbilla Atiah Leonard Kofitse Amekudzi Jeffrey Nii Armah Aryee Kwasi Preko Sylvester Kojo Danuor In regions of sparse gauge networks, satellite rainfall products are mostly used as surrogate measurements for various rainfall impact studies. Their potential to complement rain gauge measurements is influenced by...
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Atmosphere, Vol. 11, Pages 858: Spatial-Temporal Pattern Changes of UTCI in the China–Pakistan Economic Corridor in Recent 40 Years Atmosphere doi: 10.3390/atmos11080858 Authors: Zeng Wu Mu Deng Wei Sun This paper investigated the spatial and temporal variations of the Universal Thermal Climate Index (UTCI) of the China-Pakistan Economic Corridor (CPEC) from 1979 to 2018. The European Centre for Medium-Range Weather Forecasts Re-Analysis-Interim (ERA-Interim) reanalysis...
Thu Aug 13, 2020 03:00
Atmosphere, Vol. 11, Pages 856: Accurate, Low Cost PM2.5 Measurements Demonstrate the Large Spatial Variation in Wood Smoke Pollution in Regional Australia and Improve Modeling and Estimates of Health Costs Atmosphere doi: 10.3390/atmos11080856 Authors: Dorothy L. Robinson The accuracy and utility of low-cost PM2.5 sensors was evaluated for measuring spatial variation and modeling population exposure to PM2.5 pollution from domestic wood-heating (DWH) in Armidale, a regional town in...
Thu Aug 13, 2020 03:00
Atmosphere, Vol. 11, Pages 857: Cloudiness Information Services for Solar Energy Management in West Africa Atmosphere doi: 10.3390/atmos11080857 Authors: Danso Anquetin Diedhiou Adamou In West Africa (WA), interest in solar energy development has risen in recent years with many planned and ongoing projects currently in the region. However, a major drawback to this development in the region is the intense cloud cover that reduces the incoming solar radiation when present...
Thu Aug 13, 2020 03:00
Atmosphere, Vol. 11, Pages 855: Refinements to Data Acquired by 2-Dimensional Video Disdrometers Atmosphere doi: 10.3390/atmos11080855 Authors: Michael L. Larsen Christopher K. Blouin The 2-Dimensional Video Disdrometer (2DVD) is a commonly used tool for exploring rain microphysics and for validating remotely sensed rain retrievals. Recent work has revealed a persistent anomaly in 2DVD data. Early investigations of this anomaly concluded that the resulting errors in rain measurement...
Thu Aug 13, 2020 03:00
Atmosphere, Vol. 11, Pages 854: Multi-Scale Transects of Three North American Drylines Atmosphere doi: 10.3390/atmos11080854 Authors: Loren D. White Duanjun Lu North American drylines are distinct air mass boundaries that have often been examined for their relation to the initiation of severe convective storms. Three cases of drylines occurring in synoptically quiescent environments are analyzed using data obtained from a single mobile platform in concert with data from operational...
Thu Aug 13, 2020 03:00
Bioengineering, Vol. 7, Pages 94: Recent Advances of Polyaniline-Based Biomaterials for Phototherapeutic Treatments of Tumors and Bacterial Infections Bioengineering doi: 10.3390/bioengineering7030094 Authors: Chiranjeevi Korupalli Poliraju Kalluru Karthik Nuthalapati Naresh Kuthala Suresh Thangudu Raviraj Vankayala Conventional treatments fail to completely eradicate tumor or bacterial infections due to their inherent shortcomings. In recent years, photothermal therapy...
Thu Aug 13, 2020 03:00
Biology, Vol. 9, Pages 223: Botanical Products in the Treatment and Control of Schistosomiasis: Recent Studies and Distribution of Active Plant Resources According to Affected Regions Biology doi: 10.3390/biology9080223 Authors: Ricardo Diego Duarte Galhardo de Albuquerque Mohamad Fawzi Mahomoodally Devina Lobine Shanno Suroowan Kannan RR Rengasamy Schistosomiasis, a parasitic disease caused by trematodes of the genus Schistosoma, is the second most prevalent parasitic disease...
Thu Aug 13, 2020 03:00
Biology, Vol. 9, Pages 222: Artificial Neural Networks Model for Predicting Type 2 Diabetes Mellitus Based on VDR Gene FokI Polymorphism, Lipid Profile and Demographic Data Biology doi: 10.3390/biology9080222 Authors: Ma’mon M. Hatmal Salim M. Abderrahman Wajeha Nimer Zaynab Al-Eisawi Hamzeh J. Al-Ameer Mohammad A. I. Al-Hatamleh Rohimah Mohamud Walhan Alshaer Type 2 diabetes mellitus (T2DM) is a multifactorial disease associated with many genetic polymorphisms;...
Thu Aug 13, 2020 03:00
Biology, Vol. 9, Pages 221: The Teleost Thymus in Health and Disease: New Insights from Transcriptomic and Histopathological Analyses of Turbot, Scophthalmus maximus Biology doi: 10.3390/biology9080221 Authors: Paolo Ronza Diego Robledo Ana Paula Losada Roberto Bermúdez Belén G. Pardo Paulino Martínez María Isabel Quiroga The thymus is a primary lymphoid organ that plays a pivotal role in the adaptive immune system. The immunobiology of the thymus in fish is considered...
Thu Aug 13, 2020 03:00
Biomedicines, Vol. 8, Pages 286: Dietary Flavonoids in p53—Mediated Immune Dysfunctions Linking to Cancer Prevention Biomedicines doi: 10.3390/biomedicines8080286 Authors: Shoib Sarwar Siddiqui Sofia Rahman H.P. Vasantha Rupasinghe Cijo George Vazhappilly The p53 protein plays a central role in mediating immune functioning and determines the fate of the cells. Its role as a tumor suppressor, and in transcriptional regulation and cytokine activity under stress conditions, is...
Thu Aug 13, 2020 03:00
Biomedicines, Vol. 8, Pages 285: Non-Pharmacological Treatment of Refractory Angina and Microvascular Angina Biomedicines doi: 10.3390/biomedicines8080285 Authors: Kudrat Rakhimov Tommaso Gori Refractory angina (RA) is defined as debilitating anginal symptoms despite the optimal guideline-directed combination of medical, percutaneous, and surgical therapies. Often referred to as “no option”, these patients represent a significant unmet clinical need for healthcare...
Thu Aug 13, 2020 03:00
Biomolecules, Vol. 10, Pages 1179: Dietary Supplementation with Sugar Beet Fructooligosaccharides and Garlic Residues Promotes Growth of Beneficial Bacteria and Increases Weight Gain in Neonatal Lambs Biomolecules doi: 10.3390/biom10081179 Authors: Narciso M. Quijada Raúl Bodas Jose M. Lorenzo Stephan Schmitz-Esser David Rodríguez-Lázaro Marta Hernández The proper development of the early gastrointestinal tract (GIT) microbiota is critical for newborn ruminants. This microbiota...
Thu Aug 13, 2020 03:00
Biomolecules, Vol. 10, Pages 1178: Alanyl-Glutamine Restores Tight Junction Organization after Disruption by a Conventional Peritoneal Dialysis Fluid Biomolecules doi: 10.3390/biom10081178 Authors: Maria Bartosova Rebecca Herzog David Ridinger Eszter Levai Hanna Jenei Conghui Zhang Guadalupe T. González Mateo Iva Marinovic Thilo Hackert Felix Bestvater Michael Hausmann Manuel López Cabrera Klaus Kratochwill Sotirios G. Zarogiannis Claus Peter Schmitt...
Thu Aug 13, 2020 03:00
Brain Sciences, Vol. 10, Pages 553: The Involvement of Exosomes in Glioblastoma Development, Diagnosis, Prognosis, and Treatment Brain Sciences doi: 10.3390/brainsci10080553 Authors: Adrian Bălașa Georgiana Șerban Rareş Chinezu Corina Hurghiș Flaviu Tămaș Doina Manu Brain tumours are a serious concern among both physicians and patients. The most feared brain tumour is glioblastoma (GBM) due to its heterogeneous histology, substantial invasive capacity, and rapid postsurgical...
Thu Aug 13, 2020 03:00
Brain Sciences, Vol. 10, Pages 552: Allocentric Spatial Memory Performance in a Virtual Reality-Based Task is Conditioned by Visuospatial Working Memory Capacity Brain Sciences doi: 10.3390/brainsci10080552 Authors: Joaquín Castillo Escamilla José Javier Fernández Castro Shishir Baliyan Juan José Ortells-Pareja Juan José Ortells Rodríguez José Manuel Cimadevilla Traditionally, the medial temporal lobe has been considered a key brain region for spatial memory. Nevertheless,...
Thu Aug 13, 2020 03:00
Brain Sciences, Vol. 10, Pages 550: Language Experience Is Associated with Infants’ Visual Attention to Speakers Brain Sciences doi: 10.3390/brainsci10080550 Authors: Natsuki Atagi Scott P. Johnson Early social-linguistic experience influences infants’ attention to faces but little is known about how infants attend to the faces of speakers engaging in conversation. Here, we examine how monolingual and bilingual infants attended to speakers during a conversation, and we tested...
Thu Aug 13, 2020 03:00
Brain Sciences, Vol. 10, Pages 551: A Novel Mutual Information Based Feature Set for Drivers’ Mental Workload Evaluation Using Machine Learning Brain Sciences doi: 10.3390/brainsci10080551 Authors: Mir Riyanul Islam Shaibal Barua Mobyen Uddin Ahmed Shahina Begum Pietro Aricò Gianluca Borghini Gianluca Di Flumeri Analysis of physiological signals, electroencephalography more specifically, is considered a very promising technique to obtain objective measures for mental...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2274: Mechanisms of T-Cell Exhaustion in Pancreatic Cancer Cancers doi: 10.3390/cancers12082274 Authors: Didem Saka Muazzez Gökalp Betül Piyade Nedim Can Cevik Elif Arik Sever Derya Unutmaz Güralp O. Ceyhan Ihsan Ekin Demir Hande Asimgil T-cell exhaustion is a phenomenon that represents the dysfunctional state of T cells in chronic infections and cancer and is closely associated with poor prognosis in many cancers. The endogenous T-cell...
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Cancers, Vol. 12, Pages 2272: Targeting Gut Microbial Biofilms—A Key to Hinder Colon Carcinogenesis?
Cancers, Vol. 12, Pages 2272: Targeting Gut Microbial Biofilms—A Key to Hinder Colon Carcinogenesis? Cancers doi: 10.3390/cancers12082272 Authors: Siang-Siang Chew Loh Teng-Hern Tan Jodi Woan-Fei Law Priyia Pusparajah Bey-Hing Goh Nurul Syakima Ab Mutalib Learn-Han Lee Colorectal cancer (CRC) is a global public health issue which poses a substantial humanistic and economic burden on patients, healthcare systems and society. In recent years, intestinal dysbiosis has...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2270: A Phase II Study of Glembatumumab Vedotin for Metastatic Uveal Melanoma Cancers doi: 10.3390/cancers12082270 Authors: Merve Hasanov Matthew J. Rioth Kari Kendra Leonel Hernandez-Aya Richard W. Joseph Stephen Williamson Sunandana Chandra Keisuke Shirai Christopher D. Turner Karl Lewis Elizabeth Crowley Jeffrey Moscow Brett Carter Sapna Patel Glembatumumab vedotin (CDX-011, GV) is a fully human Immunoglobulin G2 monoclonal...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2271: Oncological Outcomes of Metastasis-Directed Therapy in Oligorecurrent Prostate Cancer Patients Following Radical Prostatectomy Cancers doi: 10.3390/cancers12082271 Authors: Gaëtan Devos Charlien Berghen Henri Van Eecke Arthur Vander Stichele Hendrik Van Poppel Karolien Goffin Cindy Mai Liesbeth De Wever Maarten Albersen Wouter Everaerts Gert De Meerleer Steven Joniau Several retrospective and a few prospective studies have...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2273: Verification of Saliva Matrix Metalloproteinase-1 as a Strong Diagnostic Marker of Oral Cavity Cancer Cancers doi: 10.3390/cancers12082273 Authors: Ya-Ting Chang Lichieh Julie Chu Yen-Chun Liu Chih-Jou Chen Shu-Fang Wu Chien-Hua Chen Ian Yi-Feng Chang Jun-Sheng Wang Tzong-Yuan Wu Srinivas Dash Wei-Fan Chiang Sheng-Fu Chiu Shin-Bin Gou Chih-Yen Chien Kai-Ping Chang Jau-Song Yu Oral squamous cell carcinoma (OSCC)...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2269: CD83, a Novel MAPK Signaling Pathway Interactor, Determines Ovarian Cancer Cell Fate Cancers doi: 10.3390/cancers12082269 Authors: Aalia Batool Hao Liu Yi-Xun Liu Su-Ren Chen Ovarian cancer is a leading cause of death from gynecologic malignancies worldwide. Although CD83 is widely described as a solid marker for mature dendritic cells, emerging pieces of evidence indicate the expression of membrane protein CD83 by various tumor cells, including...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2267: Prognostic Significance of Incidental Deep Vein Thrombosis in Patients with Cancer Presenting with Incidental Pulmonary Embolism Cancers doi: 10.3390/cancers12082267 Authors: Maria Barca-Hernando Rocio Ortega-Rivera Sergio Lopez-Ruz Teresa Elias-Hernandez Maria Isabel Asensio-Cruz Samira Marin-Romero Javier Toral Emilio Montero Veronica Sanchez Elena Arellano Jose Maria Sanchez-Diaz Macarena Real-Dominguez Remedios Otero-Candelera...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2268: Cyclin E2 Promotes Whole Genome Doubling in Breast Cancer Cancers doi: 10.3390/cancers12082268 Authors: Christine Lee Kristine J. Fernandez Sarah Alexandrou C. Marcelo Sergio Niantao Deng Samuel Rogers Andrew Burgess C. Elizabeth Caldon Genome doubling is an underlying cause of cancer cell aneuploidy and genomic instability, but few drivers have been identified for this process. Due to their physiological roles in the genome reduplication...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2264: Expression Patterns of Coagulation Factor XIII Subunit A on Leukemic Lymphoblasts Correlate with Clinical Outcome and Genetic Subtypes in Childhood B-cell Progenitor Acute Lymphoblastic Leukemia Cancers doi: 10.3390/cancers12082264 Authors: Bettina Kárai Katalin Gyurina Anikó Ujfalusi Łukasz Sędek Gábor Barna Pál Jáksó Peter Svec Eszter Szánthó Attila Csaba Nagy Judit Müller Réka Simon Ágnes Vojczek István Szegedi Lilla Györgyi...
Thu Aug 13, 2020 03:00
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