Cancers, Vol. 12, Pages 2265: Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions Cancers doi: 10.3390/cancers12082265 Authors: Katja Steiger Nina Gross Sebastian A. Widholz Roland Rad Wilko Weichert Carolin Mogler Genetically engineered mouse models (GEMM) are an elegant tool to study liver carcinogenesis in vivo. Newly designed mouse models need detailed (histopathological) phenotyping...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2262: HSP70–eIF4G Interaction Promotes Protein Synthesis and Cell Proliferation in Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12082262 Authors: Meng Wang Kai Wei Baifeng Qian Svenja Feiler Anastasia Lemekhova Markus W. Büchler Katrin Hoffmann Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide and features various tumor escape mechanisms from treatment-induced stress. HSP70 plays a critical role...
Thu Aug 13, 2020 03:00
Cancers, Vol. 12, Pages 2266: mTOR Inhibition Leads to Src-Mediated EGFR Internalisation and Degradation in Glioma Cells Cancers doi: 10.3390/cancers12082266 Authors: Barbara Colella Mayra Colardo Gianna Iannone Claudia Contadini Cristina Saiz-Ladera Claudia Fuoco Daniela Barilà Guillermo Velasco Marco Segatto Sabrina Di Bartolomeo Epidermal Growth Factor receptor (EGFR) is a tyrosine kinase receptor widely expressed on the surface of numerous cell types, which...
Thu Aug 13, 2020 03:00
Cells, Vol. 9, Pages 1900: A Scaffold-Free 3-D Co-Culture Mimics the Major Features of the Reverse Warburg Effect In Vitro Cells doi: 10.3390/cells9081900 Authors: Keller Bruch Schneider Meier-Hubberten Hafner Rudolf Most tumors consume large amounts of glucose. Concepts to explain the mechanisms that mediate the achievement of this metabolic need have proposed a switch of the tumor mass to aerobic glycolysis. Depending on whether primarily tumor or stroma cells...
Thu Aug 13, 2020 03:00
Cells, Vol. 9, Pages 1896: Advances in Therapeutic Targeting of Cancer Stem Cells within the Tumor Microenvironment: An Updated Review Cells doi: 10.3390/cells9081896 Authors: Kevin Dzobo Dimakatso Alice Senthebane Chelene Ganz Nicholas Ekow Thomford Ambroise Wonkam Collet Dandara Despite great strides being achieved in improving cancer patients’ outcomes through better therapies and combinatorial treatment, several hurdles still remain due to therapy resistance,...
Thu Aug 13, 2020 03:00
Cells, Vol. 9, Pages 1899: A Novel Approach for Detecting Unique Variations among Infectious Bacterial Species in Endocarditic Cardiac Valve Vegetation Cells doi: 10.3390/cells9081899 Authors: Hannachi Lepidi Fontanini Takakura Bou-Khalil Gouriet Habib Raoult Camoin-Jau Baudoin Infectious endocarditis (IE) remains one of the deadliest heart diseases with a high death rate, generally following thrombo-embolic events. Today, therapy is based on surgery...
Thu Aug 13, 2020 03:00
Cells, Vol. 9, Pages 1898: The N-Terminus Makes the Difference: Impact of Genotype-Specific Disparities in the N-Terminal Part of The Hepatitis B Virus Large Surface Protein on Morphogenesis of Viral and Subviral Particles Cells doi: 10.3390/cells9081898 Authors: Bingfu Jiang Xingjian Wen Qingyan Wu Daniela Bender Gert Carra Michael Basic Alica Kubesch Kai-Henrik Peiffer Klaus Boller Eberhard Hildt The N-terminus of the hepatitis B virus (HBV) large surface...
Thu Aug 13, 2020 03:00
Cells, Vol. 9, Pages 1897: Involvement of JNK1 in Neuronal Polarization During Brain Development Cells doi: 10.3390/cells9081897 Authors: Castro-Torres Busquets Parcerisas Verdaguer Olloquequi Etchetto Beas-Zarate Folch Camins Auladell The c-Jun N-terminal Kinases (JNKs) are a group of regulatory elements responsible for the control of a wide array of functions within the cell. In the central nervous system (CNS), JNKs are involved in neuronal polarization,...
Thu Aug 13, 2020 03:00
Cells, Vol. 9, Pages 1894: Considering Cause and Effect of Immune Cell Aging on Cardiac Repair after Myocardial Infarction Cells doi: 10.3390/cells9081894 Authors: Stephanie W. Tobin Faisal J. Alibhai Richard D. Weisel Ren-Ke Li The importance of the immune system for cardiac repair following myocardial infarction is undeniable; however, the complex nature of immune cell behavior has limited the ability to develop effective therapeutics. This limitation highlights the need for...
Thu Aug 13, 2020 03:00
Cells, Vol. 9, Pages 1895: The Hippo Pathway Effector YAP1 Regulates Intestinal Epithelial Cell Differentiation Cells doi: 10.3390/cells9081895 Authors: Sepideh Fallah Jean-François Beaulieu The human intestine is covered by epithelium, which is continuously replaced by new cells provided by stem cells located at the bottom of the glands. The maintenance of intestinal stem cells is supported by a niche which is composed of several signaling proteins including the Hippo pathway effectors...
Thu Aug 13, 2020 03:00
Chemosensors, Vol. 8, Pages 69: Exposure Science in the 21st Century: Advancing the Science and Technology of Environmental Sensors through Cooperation and Collaboration across U.S. Federal Agencies Chemosensors doi: 10.3390/chemosensors8030069 Authors: Hulla Kilaru Doucette Balshaw Watkins The convergence of technological innovations in areas such as microelectronics, fabrication, the Internet-of-things (IoT), and smartphones, along with their associated “apps”,...
Thu Aug 13, 2020 03:00
Diagnostics, Vol. 10, Pages 590: MRI and Active Surveillance for Prostate Cancer Diagnostics doi: 10.3390/diagnostics10080590 Authors: Angelo Porreca Michele Colicchia Gian Maria Busetto Matteo Ferro Since the introduction of Prostate-Specific Antigen (PSA) screening, prostate cancer mortality has decreased [...]
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Diagnostics, Vol. 10, Pages 588: Quantitative Multiplex Real-Time Reverse Transcriptase–Polymerase Chain Reaction with Fluorescent Probe Detection of Killer Immunoglobulin-Like Receptors, KIR2DL4/3DL3 Diagnostics doi: 10.3390/diagnostics10080588 Authors: Wipaporn Wongfieng Rungtiwa Nutalai Amonrat Jumnainsong Chanvit Leelayuwat (1) Background: KIR2DL4/KIR3DL3 are the framework genes present in all KIR haplotypes, with unique expression patterns being present only in women and...
Thu Aug 13, 2020 03:00
Diagnostics, Vol. 10, Pages 586: Identifying the Salient Genes in Microarray Data: A Novel Game Theoretic Model for the Co-Expression Network Diagnostics doi: 10.3390/diagnostics10080586 Authors: Papori Neog Bora Vishwa Jyoti Baruah Surajit Borkotokey Loyimee Gogoi Priyakshi Mahanta Ankumon Sarmah Rajnish Kumar Stefano Moretti Microarray techniques are used to generate a large amount of information on gene expression. This information can be statistically processed...
Thu Aug 13, 2020 03:00
Diagnostics, Vol. 10, Pages 587: The Role of Fecal Calprotectin in Patients with Systemic Sclerosis and Small Intestinal Bacterial Overgrowth (SIBO) Diagnostics doi: 10.3390/diagnostics10080587 Authors: Beata Polkowska-Pruszyńska Agnieszka Gerkowicz Karol Rawicz-Pruszyński Dorota Krasowska Fecal calprotectin (FC) is a quick, cost-effective, and noninvasive test, which is used to diagnose patients with active inflammatory bowel diseases (IBD). Recent studies suggest the possible...
Thu Aug 13, 2020 03:00
Diagnostics, Vol. 10, Pages 589: Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease Diagnostics doi: 10.3390/diagnostics10080589 Authors: Doreen Schmidl Andreas Schlatter Jacqueline Chua Bingyao Tan Gerhard Garhöfer Leopold Schmetterer Imaging has become indispensable in the diagnosis and management of diseases in the posterior part of the eye. In recent years, imaging techniques for the anterior segment are also gaining importance and are nowadays...
Thu Aug 13, 2020 03:00
Diagnostics, Vol. 10, Pages 585: Trends in Hospitalization of Patients with Potentially Serious Diseases Evaluated at a Quick Diagnosis Clinic Diagnostics doi: 10.3390/diagnostics10080585 Authors: Xavier Bosch Andrea Ladino Pedro Moreno-Lozano Anna Jordán Alfonso López-Soto Although quick diagnosis units (QDU) have become a cost-effective alternative to inpatient admission for diagnosis of potentially serious diseases, the rate of return hospitalizations among evaluated patients...
Thu Aug 13, 2020 03:00
Diversity, Vol. 12, Pages 312: Impact of Climate Change on the Distribution of Four Closely Related Orchis (Orchidaceae) Species Diversity doi: 10.3390/d12080312 Authors: Alexandra Evans Sam Janssens Hans Jacquemyn Long-term monitoring programs and population demographic models have shown that the population dynamics of orchids are to a large extent dependent on prevailing weather conditions, suggesting that the changes in climatic conditions can have far reaching effects on the...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1119: Development and Validation of HPLC-DAD Method for Simultaneous Determination of Seven Food Additives and Caffeine in Powdered Drinks Foods doi: 10.3390/foods9081119 Authors: Imanulkhan Imanulkhan Widiastuti Setyaningsih Abdul Rohman Miguel Palma The usage of food additives must respect the general legislation in force in the country and requires a reliable analytical method for surveillance. This research aimed to develop a high-performance liquid...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1120: Concentration of Potentially Bioactive Compounds in Italian Extra Virgin Olive Oils from Various Sources by Using LC-MS and Multivariate Data Analysis Foods doi: 10.3390/foods9081120 Authors: Anna Różańska Marina Russo Francesco Cacciola Fabio Salafia Żaneta Polkowska Paola Dugo Luigi Mondello High quality extra virgin olive oils represent an optimal source of nutraceuticals. The European Union (EU) is the world’s leading olive oil...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1116: Effects of Ultra-Sonication and Agitation on Bioactive Compounds and Structure of Amaranth Extract Foods doi: 10.3390/foods9081116 Authors: Maruf Ahmed Karna Ramachandraiah Gui-Hun Jiang Jong Bang Eun Amaranth is an excellent source of various bioactive compounds that could be beneficial in the prevention of some human diseases. This study investigated the extraction and characterization of bioactive compounds from amaranth using ultra-sonication and...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1117: Characterization and Antimicrobial Activity of Biodegradable Active Packaging Enriched with Clove and Thyme Essential Oil for Food Packaging Application Foods doi: 10.3390/foods9081117 Authors: Shubham Sharma Sandra Barkauskaite Brendan Duffy Amit K. Jaiswal Swarna Jaiswal Bioactive packaging contains natural antimicrobial agents, which inhibit the growth of microorganisms and increase the food shelf life. Solvent casting method was used to prepare...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1118: Volatile Composition and Sensory Properties as Quality Attributes of Fresh and Dried Hemp Flowers (Cannabis sativa L.) Foods doi: 10.3390/foods9081118 Authors: Andrzej Kwaśnica Natalia Pachura Klaudia Masztalerz Adam Figiel Aleksandra Zimmer Robert Kupczyński Katarzyna Wujcikowska Angel A. Carbonell-Barrachina Antoni Szumny Henryk Różański Flowers of hemp (Cannabis sativa L.) are widely used in cosmetics, food, and in the pharmaceutical...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1114: Factors Underlying Food Choice Motives in a Brazilian Sample: The Association with Socioeconomic Factors and Risk Perceptions about Chronic Diseases Foods doi: 10.3390/foods9081114 Authors: Camila de Mello Marsola Luís Miguel Cunha Joana Pereira de Carvalho-Ferreira Diogo Thimoteo da Cunha This study aimed to evaluate the food choice motives in a sample in Brazil and to identify how socioeconomic characteristics and risk perceptions about chronic diseases...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1115: Catfish Glycoprotein, a Highly Powerful Safe Preservative of Minced Beef Stored at 4 °C for 15 Days Foods doi: 10.3390/foods9081115 Authors: Ali Osman Seham Abdel-Shafi Abdul-Raouf Al-Mohammadi Nehal Kamal Gamal Enan Mahmoud Sitohy Minced beef is a very perishable food product, due to its vulnerability to microbial contamination and its fast quality deterioration. In the current study, the biological efficiency of different concentrations (0,...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1113: Scientific Approaches on Extraction, Purification and Stability for the Commercialization of Fucoxanthin Recovered from Brown Algae Foods doi: 10.3390/foods9081113 Authors: Catarina Lourenço-Lopes Paula Garcia-Oliveira Maria Carpena Maria Fraga-Corral Cecilia Jimenez-Lopez Antia G. Pereira Miguel A. Prieto Jesus Simal-Gandara The scientific community has corroborated the numerous beneficial activities of fucoxanthin, such as its antioxidant,...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1112: Fungi Burger from Stale Bread? A Case Study on Perceptions of a Novel Protein-Rich Food Product Made from an Edible Fungus Foods doi: 10.3390/foods9081112 Authors: Coralie Hellwig Rebecca Gmoser Magnus Lundin Mohammad J. Taherzadeh Kamran Rousta The current study aims to assess how a novel fungi product made from the filamentous fungus Neurospora intermedia, cultivated on bread residuals, is perceived using questionnaires. Participants were asked...
Thu Aug 13, 2020 03:00
Foods, Vol. 9, Pages 1111: Safety, Quality and Analytical Authentication of ḥalāl Meat Products, with Particular Emphasis on Salami: A Review Foods doi: 10.3390/foods9081111 Authors: Maria Martuscelli Annalisa Serio Oriana Capezio Dino Mastrocola Only some animal species could be transformed into ḥalāl salami and the raw meat must be obtained from ritually slaughtered animals. Several scientific studies have been conducted on ritual slaughtering practices and manufacturing of...
Thu Aug 13, 2020 03:00
Healthcare, Vol. 8, Pages 269: Relationship between the Functional Oral Intake Scale (FOIS) and the Self-Efficacy Scale among Cancer Patients: A Cross-Sectional Study Healthcare doi: 10.3390/healthcare8030269 Authors: Yuhei Matsuda Masaaki Karino Takahiro Kanno A few studies have provided detailed reports suggesting that subjective swallowing disorders may be related to dysphagia. Therefore, we verified the relationship between oral health-related self-efficacy and dysphagia severity...
Thu Aug 13, 2020 03:00
Healthcare, Vol. 8, Pages 268: Psychosocial Intervention in European Addictive Behaviour Recovery Programmes: A Qualitative Study Healthcare doi: 10.3390/healthcare8030268 Authors: Antonio Molina Jesús Saiz Francisco Gil María Luisa Cuenca Tamara Goldsby Background: The vulnerability of drug users in treatment increases their risk of social exclusion. Psychosocial interventions aim to solve or minimise this risk, increasing social integration for individuals in treatment....
Thu Aug 13, 2020 03:00
Healthcare, Vol. 8, Pages 267: A Single Case Report of Granular Cell Tumor of the Tongue Successfully Treated through 445 nm Diode Laser Healthcare doi: 10.3390/healthcare8030267 Authors: Maria Vittoria Viani Luigi Corcione Chiara Di Blasio Ronell Bologna-Molina Paolo Vescovi Marco Meleti Oral granular cell tumor (GCT) is a relatively rare, benign lesion that can easily be misdiagnosed. Particularly, the presence of pseudoepitheliomatous hyperplasia might, in some cases,...
Thu Aug 13, 2020 03:00
Heritage, Vol. 3, Pages 891-914: Early Observations on the Steamer Bengala (Formerly Named Mecca and Livorno) Sunk off Capo Rizzuto (Crotone, Italy) in 1889 Heritage doi: 10.3390/heritage3030049 Authors: Salvatore Medaglia Francesco Megna Luca De Rosa In the waters of the Calabrian Ionian Sea, off Isola di Capo Rizzuto (Crotone, Italy) and at a depth of 26–29 m, lies the wreck of Bengala, an iron screw-steamer foundered in 1889. She was built and launched in 1871 in Sunderland...
Thu Aug 13, 2020 03:00
IJERPH, Vol. 17, Pages 5895: Personalized Tracking of Physical Activity in Children Using a Wearable Heart Rate Monitor International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17165895 Authors: Santiago A. Pérez Ana M. Díaz Diego M. López Serious games are video games that are intended to support learning while entertaining. They are considered valuable tools to improve user-specific skills or facilitate educational or therapeutic processes, especially...
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IJERPH, Vol. 17, Pages 5894: Sexual and Life Satisfaction of Pregnant Women International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17165894 Authors: Dorota Branecka-Woźniak Anna Wójcik Joanna Błażejewska-Jaśkowiak Rafał Kurzawa The awareness of one’s own sexuality and its expression depend on the stage of an individual’s life. Pregnancy is a period of many, also psychosexual, changes. The sexual needs of pregnant women are rarely...
Thu Aug 13, 2020 03:00
IJERPH, Vol. 17, Pages 5893: Key Guidelines in Developing a Pre-Emptive COVID-19 Vaccination Uptake Promotion Strategy International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17165893 Authors: French Deshpande Evans Obregon This paper makes the case for immediate planning for a COVID-19 vaccination uptake strategy in advance of vaccine availability for two reasons: first, the need to build a consensus about the order in which groups of the population...
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IJERPH, Vol. 17, Pages 5892: An Exploratory Study on Sleep Procrastination: Bedtime vs. While-in-Bed Procrastination International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17165892 Authors: Paula Magalhães Vânia Cruz Sara Teixeira Sónia Fuentes Pedro Rosário Sleep Procrastination literature has focused on the behaviors individuals engage in before going to bed (Bedtime Procrastination) but not on the behaviors individuals engage in after going...
Thu Aug 13, 2020 03:00
IJERPH, Vol. 17, Pages 5879: Value-Based Healthcare in Ostomies International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17165879 Authors: Ana C. Montesinos Gálvez Francisco Jódar Sánchez Carmen Alcántara Moreno Antonio J. Pérez Fernández Rosario Benítez García Mercedes Coca López María Paz Bienvenido Ramírez Monserrat Cabrera López Luisa Vázquez Burrero Pilar Jurado Berja Raquel Sánchez García Josefa Martín Cebrián María Luz...
Thu Aug 13, 2020 03:00
IJERPH, Vol. 17, Pages 5891: Increasing Health Literacy May Reduce Health Inequalities: Evidence from a National Population Survey in Ireland International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17165891 Authors: Gibney Bruton Ryan Doyle Rowlands Background. Health literacy has been separately associated with socio-economic status and worse health status and outcomes. However, the magnitude of the associations between health literacy and...
Thu Aug 13, 2020 03:00
IJERPH, Vol. 17, Pages 5890: Spatial and Temporal Impacts of Socioeconomic and Environmental Factors on Healthcare Resources: A County-Level Bayesian Local Spatiotemporal Regression Modeling Study of Hospital Beds in Southwest China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17165890 Authors: Song Wang Yang Yang Tang Wang Pan Comprehensive investigation on understanding geographical inequalities of healthcare resources...
Thu Aug 13, 2020 03:00
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