Determinants of choice in offering drug holidays during first-line therapy for metastatic colorectal cancer. Future Oncol. 2020 Aug 10;: Authors: Garattini SK, Bonotto M, Porcu L, Ongaro E, Gerratana L, Basile D, Parnofiello A, Pelizzari G, Cortiula F, Corvaja C, Casagrande M, Cardellino GG, Buonadonna A, Aprile G, Puglisi F, Fasola G, Pella N Abstract Background: "Drug holidays" (DH) for metastatic colorectal cancer (mCRC) were introduced...
Tue Aug 11, 2020 13:31
Recapitulating intracavitary brachytherapy in cervical cancer patients during the COVID-19 pandemic: a viewpoint. Future Oncol. 2020 Aug 10;: Authors: Kumar D, Dey T PMID: 32776790 [PubMed - as supplied by publisher]
Tue Aug 11, 2020 13:31
A systems biology approach to discovering pathway signaling dysregulation in metastasis. Cancer Metastasis Rev. 2020 Aug 10;: Authors: Clarke R, Kraikivski P, Jones BC, Sevigny CM, Sengupta S, Wang Y Abstract Total metastatic burden is the primary cause of death for many cancer patients. While the process of metastasis has been studied widely, much remains to be understood. Moreover, few agents have been developed that specifically target the...
Tue Aug 11, 2020 13:31
Continuing Medical Student Education During the Coronavirus Disease 2019 (COVID-19) Pandemic: Development of a Virtual Radiation Oncology Clerkship. Adv Radiat Oncol. 2020 Jul-Aug;5(4):732-736 Authors: Pollom EL, Sandhu N, Frank J, Miller JA, Obeid JP, Kastelowitz N, Panjwani N, Soltys SG, Bagshaw HP, Donaldson SS, Horst K, Beadle BM, Chang DT, Gibbs I Abstract Purpose: Our institution cancelled all in-person clerkships owing to the coronavirus...
Tue Aug 11, 2020 13:31
Cancer control in Ghana: A narrative review in global context. Heliyon. 2020 Aug;6(8):e04564 Authors: Mensah KB, Mensah ABB Abstract Globally, cancer is likely to be ranked as the leading cause of death among non-communicable diseases in the 21st century. In Ghana, estimates suggest that the disease is expected to increase continuously. The best way to address the increasing burden is through a comprehensive cancer control program. This paper...
Tue Aug 11, 2020 13:31
Propelling Health Care into the Twenties. Biomed Hub. 2020 May-Aug;5(2):15-67 Authors: Horgan D, Borisch B, Richer E, Bernini C, Kalra D, Lawler M, Ciliberto G, Van Poppel H, Paradiso A, Riegman P, Triberti S, Metspalu A, Chiti A, Macintyre E, Boccia S, Calvo F, Schatz D, Koeva-Balabanova J, Jonsson B Abstract The scope and potential of personalised health care are underappreciated and underrealised, often because of resistance to change. The...
Tue Aug 11, 2020 13:31
Risk assessment criteria in liver transplantation for hepatocellular carcinoma: proposal to improve transplant oncology. Hepat Oncol. 2020 Jul 24;7(3):HEP26 Authors: McVey JC, Sasaki K, Firl DJ Abstract Liver transplantation for hepatocellular carcinoma has proved to be a highly effective cure if the right patient can be selected. Milan criteria has traditionally guided physicians toward appropriate liver allocation but changes in clinical...
Tue Aug 11, 2020 13:31
Cynanchum paniculatum and Its Major Active Constituents for Inflammatory-Related Diseases: A Review of Traditional Use, Multiple Pathway Modulations, and Clinical Applications. Evid Based Complement Alternat Med. 2020;2020:7259686 Authors: Chen JX, Cheng CS, Chen J, Lv LL, Chen ZJ, Chen C, Zheng L Abstract Cynanchum paniculatum Radix, known as Xuchangqing in Chinese, is commonly prescribed in Chinese Medicine (CM) for the treatment of various...
Tue Aug 11, 2020 13:31
The Mechanism of Ferroptosis and Applications in Tumor Treatment. Front Pharmacol. 2020;11:1061 Authors: Lin X, Ping J, Wen Y, Wu Y Abstract Iron-dependent ferroptosis is a new form of cell death in recent years, which is driven by lipid peroxidation. The lethal lipid accumulation caused by glutathione depletion or inactivation of glutathione peroxidase 4 (GPX4) is characteristic of the ferroptosis process. In recent years, with the in-depth...
Tue Aug 11, 2020 13:31
Current Status on Population Genome Catalogues in different Countries. Bioinformation. 2020;16(4):297-300 Authors: Kumar R, Dhanda SK Abstract Genomics has become indispensable for research in the last two decades. Completed and ongoing genome projects such as the UK Biobank, ICGC, TCGA and GenomeAsia100K have helped to understand several life-threatening diseases like cancer. Such initiatives from different countries have offered genomics-based...
Tue Aug 11, 2020 13:31
[Present and Future of Efficacy Biomarkers in Immune Checkpoint Inhibitors
of Small-cell Lung Cancer]. Zhongguo Fei Ai Za Zhi. 2020 Aug 10;: Authors: Yang Y, Wang Y Abstract Inhibitions of immune checkpoints, including programmed death 1-programmed death-ligand 1 (PD-1-PD-L1) axis, CTLA-4, are at the forefront of immunotherapy for small-cell lung cancer. However, the survival benefits emerged after three to six months since therapy initiation....
Tue Aug 11, 2020 13:31
Clinical Characteristics Associated With Stuttering Persistence: A Meta-Analysis. J Speech Lang Hear Res. 2020 Aug 10;:1-24 Authors: Singer CM, Hessling A, Kelly EM, Singer L, Jones RM Abstract Purpose The purpose of this meta-analytic study was to identify clinical characteristics, defined as child factors that can be assessed by a speech-language pathologist as part of a routine speech-language evaluation that may differentiate children who...
Tue Aug 11, 2020 13:31
Developing a growing cancer profile database based on quantitative analysis of protein biomarkers in formalin-fixed paraffin-embedded specimens. Future Oncol. 2020 Aug 08;: Authors: Zhang J, Yang M Abstract Over a century of clinical practice has led to the accumulation of millions of archived formalin fixed paraffin embedded (FFPE) cancer specimens with detailed medical records worldwide. Absolute quantitation of clinical protein biomarkers...
Tue Aug 11, 2020 13:31
Adjuvant systemic treatment in hepatocellular carcinoma: tempted to do something, rather than nothing. Future Oncol. 2020 Aug 08;: Authors: Rizzo A, Ricci AD, Brandi G PMID: 32772560 [PubMed - as supplied by publisher]
Tue Aug 11, 2020 13:31
Plain Language Summary of Publication articles: helping disseminate published scientific articles to patients. Future Oncol. 2020 Aug 10;: Authors: Dormer L, Walker J PMID: 32772553 [PubMed - as supplied by publisher]
Tue Aug 11, 2020 13:31
Related Articles Current status of intensity-modulated radiation therapy for prostate cancer: History, clinical results and future directions. Int J Urol. 2019 08;26(8):775-784 Authors: Hatano K, Tohyama N, Kodama T, Okabe N, Sakai M, Konoeda K Abstract External beam radiotherapy has changed dramatically over several decades with the improvement of computer hardware and software, and machinery developments. Intensity-modulated radiation therapy...
Tue Aug 11, 2020 13:31
Related Articles Advanced Intrahepatic Cholangiocarcinoma: Post Hoc Analysis of the ABC-01, -02, and -03 Clinical Trials. J Natl Cancer Inst. 2020 02 01;112(2):200-210 Authors: Lamarca A, Ross P, Wasan HS, Hubner RA, McNamara MG, Lopes A, Manoharan P, Palmer D, Bridgewater J, Valle JW Abstract BACKGROUND: The incidence of intrahepatic cholangiocarcinoma (iCCA) is increasing. The aim of the study was to provide reference survival data for patients...
Tue Aug 11, 2020 13:31
Related Articles Imaging and diagnostic advances for intracranial meningiomas. Neuro Oncol. 2019 01 14;21(Suppl 1):i44-i61 Authors: Huang RY, Bi WL, Griffith B, Kaufmann TJ, la Fougère C, Schmidt NO, Tonn JC, Vogelbaum MA, Wen PY, Aldape K, Nassiri F, Zadeh G, Dunn IF, International Consortium on Meningiomas Abstract The archetypal imaging characteristics of meningiomas are among the most stereotypic of all central nervous system (CNS) tumors....
Tue Aug 11, 2020 13:31
33 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Oncol Lett"[jour] These pubmed results were generated on 2020/08/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Aug 11, 2020 15:01
33 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Oncol Lett"[jour] These pubmed results were generated on 2020/08/11PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Aug 11, 2020 13:04
Correction: SNiPER: a novel hypermethylation biomarker panel for liquid biopsy based early breast cancer detection. Oncotarget. 2020 Jul 28;11(30):2958 Authors: Mijnes J, Tiedemann J, Eschenbruch J, Gasthaus J, Bringezu S, Bauerschlag D, Maass N, Arnold N, Weimer J, Anzeneder T, Fasching PA, Rübner M, Bruno B, Heindrichs U, Freres J, Schulz H, Hilgers RD, Ortiz-Brüchle N, von Serenyi S, Knüchel R, Kloten V, Dahl E Abstract [This corrects...
Tue Aug 11, 2020 13:08
Correction: Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: Involvement of p53/FoxO3A axis. Oncotarget. 2020 Jul 28;11(30):2956-2957 Authors: Nepal S, Kim MJ, Hong JT, Kim SH, Sohn DH, Lee SH, Song K, Choi DY, Lee ES, Park PH Abstract [This corrects the article DOI: 10.18632/oncotarget.3347.]. PMID: 32774774 [PubMed - as supplied by publisher]
Tue Aug 11, 2020 13:08
cGAS-STING pathway in oncogenesis and cancer therapeutics. Oncotarget. 2020 Jul 28;11(30):2930-2955 Authors: Hoong BYD, Gan YH, Liu H, Chen ES Abstract The host innate immunity offers the first line of defense against infection. However, recent evidence shows that the host innate immunity is also critical in sensing the presence of cytoplasmic DNA derived from genomic instability events, such as DNA damage and defective cell cycle progression....
Tue Aug 11, 2020 13:08
Induction of phenotypic changes in HER2-postive breast cancer cells in vivo and in vitro. Oncotarget. 2020 Jul 28;11(30):2919-2929 Authors: Frank-Kamenetskii A, Mook J, Reeves M, Boulanger CA, Meyer TJ, Ragle L, Jordan HC, Smith GH, Booth BW Abstract The influence of breast cancer cells on normal cells of the microenvironment, such as fibroblasts and macrophages, has been heavily studied but the influence of normal epithelial cells on...
Tue Aug 11, 2020 13:08
Biomarker analysis to predict the pathological response to neoadjuvant chemotherapy in locally advanced gastric cancer: An exploratory biomarker study of COMPASS, a randomized phase II trial. Oncotarget. 2020 Jul 28;11(30):2906-2918 Authors: Oshima T, Yoshikawa T, Miyagi Y, Morita S, Yamamoto M, Tanabe K, Nishikawa K, Ito Y, Matsui T, Kimura Y, Yokose T, Hiroshima Y, Aoyama T, Hayashi T, Ogata T, Cho H, Rino Y, Masuda M, Tsuburaya A, Sakamoto J ...
Tue Aug 11, 2020 13:08
Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer. Oncotarget. 2020 Jul 28;11(30):2889-2905 Authors: Narvaez CJ, LaPorta E, Robilotto S, Liang J, Welsh J Abstract 1,25-Dihydroxyvitamin D3 (1,25D3) induces growth arrest and apoptosis in breast cancer cells in vivo and in vitro, however the exact mechanisms are unclear. Although the vitamin D receptor (VDR), a ligand dependent transcription factor,...
Tue Aug 11, 2020 13:08
Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo. Oncotarget. 2020 Jul 28;11(30):2873-2888 Authors: Showalter L, Czerniecki BJ, Koski GK Abstract Targeted drug approaches have been a major focus for developing new anticancer therapies. Although many such agents approved in the last 20 years have improved outcomes, almost all have underperformed...
Tue Aug 11, 2020 13:08
CYP2 C9 polymorphism among patients with oral squamous cell carcinoma and its role in altering the metabolism of benzo[a]pyrene. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 04;: Authors: R H, Ramani P, Ramanathan A, R JM, S G, Ramasubramanian A, K M Abstract OBJECTIVES: The aim of this study was to evaluate the prevalence of CYP2 C9 polymorphism among healthy controls and patients with oral squamous cell carcinoma (OSCC) and to...
Tue Aug 11, 2020 15:38
Evaluation of mercury release from dental amalgam after cone beam computed tomography and magnetic resonance imaging with 3.0-T and 1.5-T magnetic field strengths. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 21;: Authors: Ozdede M, Yilmaz S Abstract OBJECTIVES: This in vitro study aimed to investigate leakage of mercury from amalgam restorations after cone beam computed tomography (CBCT) and magnetic resonance imaging (MRI) examinations....
Tue Aug 11, 2020 15:38
Application of pamidronate disodium for the treatment of diffuse sclerosing osteomyelitis of the mandible: a clinical study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 08;: Authors: Li X, Jia K, An J, Zhang Y Abstract OBJECTIVE: This study aimed to assess the clinical effectiveness of using pamidronate disodium to treat patients with diffuse sclerosing osteomyelitis of the mandible (DSOM ). STUDY DESIGN: Patients with...
Tue Aug 11, 2020 15:38
Malignant transformation in oral lichen planus and lichenoid lesions: a 14-year longitudinal retrospective cohort study of 829 patients in New Zealand. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 08;: Authors: Guan G, Mei L, Polonowita A, Hussaini H, Seo B, Rich AM Abstract OBJECTIVE: The aim of this study was to identify the rate of malignant transformation in a longitudinal cohort of patients with oral lichen planus and oral...
Tue Aug 11, 2020 15:38
A large mandibular soft tissue lesion in an 8-year-old boy. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 03;: Authors: Bawazir M, Banasser A, Islam NM, Bhattacharyya I, Cohen DM PMID: 32771413 [PubMed - as supplied by publisher]
Tue Aug 11, 2020 15:38
Hyaline fibromatosis syndrome: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 04;: Authors: Pereira TDSF, Sales JF, Travassos DV, Lanza CR, Castro WH, Gomes CC, Fonseca FP, Silva TA, Gomez RS Abstract Hyaline fibromatosis syndrome (HFS) is a rare monogenic disease inherited in an autosomal recessive pattern and characterized by hyaline deposits on the skin, mucosa, and multiple organs; osteoporosis; and joint contractures....
Tue Aug 11, 2020 15:38
Letter to the Editor concerning "Tracheal injury complicating Sistrunk's thyroglossal cyst surgery".
Letter to the Editor concerning "Tracheal injury complicating Sistrunk's thyroglossal cyst surgery". Eur Ann Otorhinolaryngol Head Neck Dis. 2020 Aug 06;: Authors: Garcia D PMID: 32773334 [PubMed - as supplied by publisher]
01:59
Idiopathic Subglottic Stenosis during Pregnancy: A Support Group Survey. Ann Otol Rhinol Laryngol. 2020 Aug 08;:3489420947780 Authors: McCrary H, Torrecillas V, Conley M, Anderson C, Smith M Abstract OBJECTIVES: (1) To determine how pregnancy affects idiopathic subglottic stenosis (iSGS) symptoms. (2) To determine treatments utilized (including operating room (OR) and in-office procedures) for iSGS before, during, and after pregnancy....
Tue Aug 11, 2020 14:35
Transmastoid and Transtemporal Drainage of Petrous Apicitis with Otitis Media. Ann Otol Rhinol Laryngol. 2020 Aug 08;:3489420949591 Authors: Isaac H, Liu A, Shibata SB, Hansen MR Abstract BACKGROUND: Petrous apicitis (PA) is a serious infection involving the apical portion of the petrous temporal bone. The classic triad of purulent otorrhea, ipsilateral abducens nerve palsy and retroorbital pain is rarely seen due to early detection and...
Tue Aug 11, 2020 14:35
The Postcricoid Cushion: An Unusual and Surgically Treatable Cause of Infant Aspiration. Ann Otol Rhinol Laryngol. 2020 Aug 08;:3489420948545 Authors: Jones JW, Fiorillo CE, Clark C, Bauman N Abstract OBJECTIVES: To highlight the importance of recognizing the postcricoid cushion as a surgically treatable cause of newborn aspiration in select cases unresponsive to conservative measures. METHODS: A retrospective review was performed...
Tue Aug 11, 2020 14:35
Administration of 1% topical voriconazole drops was effective and safe in the treatment of refractory otomycosis without tympanic membrane perforation. Ann Otol Rhinol Laryngol. 2020 Aug 08;:3489420946783 Authors: Zhang S, Jin M, Hu S, Zhang Y, Zhou G Abstract BACKGROUND: Refractory otomycosis is a common condition that is difficult to treat. OBJECTIVES: This study aimed to evaluate the effectiveness of 1% topical voriconazole...
Tue Aug 11, 2020 14:35
Neonatal Lateral Epiglottic Defects. Ann Otol Rhinol Laryngol. 2020 Aug 08;:3489420948546 Authors: Peterson JD, Goyal V, Puricelli MD, Thatcher A, Smith RJ Abstract INTRODUCTION: Multiple congenital abnormalities of the epiglottis have been reported and iatrogenic injuries to the larynx and subglottis are well known. We present a new pattern of defect not previously reported in the literature. METHODS: Epiglottic abnormalities...
Tue Aug 11, 2020 14:35
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