Mucosal Immunology, Published online: 13 August 2020; doi:10.1038/s41385-020-00335-wMicrobial modulation of intestinal T helper cell responses and implications for disease and therapy
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By tinkering with some of life's oldest components, astrobiologists hope to find clues about how life emerged. In a recent article researchers report an unexpected discovery, hinting at an effect that prevents organisms from ever reaching evolutionary 'perfection.'
Researchers have shed fresh light on the evolution and function of the shapes we see in nature - using as a model the heart shaped fruits of the Capsella genus.
Although overhunting led to the demise of some prehistoric megafauna after the last ice age, a new study found that the extinction of the woolly rhinoceros may have been caused by climate change. By sequencing ancient DNA from 14 woolly rhinos, researchers found that their population remained stable and diverse until only a few thousand years before it disappeared from Siberia, when temperatures likely rose too high.
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Summary The use of small interfering RNA (siRNA) in melanoma treatment remains limited owing to its biological properties. Herein, we developed a carrier system containing hyaluronic acid and protamine for siRNA delivery. Considering zeta potential and particle size as standards, the ratio of each component in liposome nanoparticles prepared was screened using the control variable method, and siRNA cationic liposome nanoparticles were prepared based on the optimal results obtained....
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The typical inscription on most Japanese tombstones does not show the names of the deceased. It says instead “Ancestral grave of the X family,” reflecting a lingering political heritage of the Meiji oligarchy (1868–1912). The imperial government established the ie (家), or the patrilineal family to which every citizen must belong, and mandated ancestor worship with the family grave as its locus to ensure the ie continuity (Tsuji 2002, 177-199). Hence, generations of family members in the direct line...
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Publication date: Available online 13 August 2020Source: American Journal of Infection ControlAuthor(s): Ramin Shiraly, Zahra Shayan, Mary-Louise McLaws
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Diet during infancy and early childhood can have implications on child growth, health, and developmental trajectories. Yet, poor dietary habits are common in young children, who often consume diets that are no...
Signals of adverse drug reactions (ADRs) form the basis of some regulatory risk-minimization actions in pharmacovigilance. Reviews of limited scope have highlighted that such signals are mostly supported by re...
A comprehensive overview of treatments of common fractures is missing, although it would be important for shared decision-making in clinical practice. The aim was to determine benefits and harms of surgical co...
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Abstract Introduction The customised birthweight model can be used to improve detection of babies that may be at risk of adverse outcomes associated with abnormal growth, however it is currently used in conjunction with either an intrauterine growth standard or the individualised birthweight ratio (IBR), both of which have significant methodological flaws. Our aim was to investigate the statistical validity of the IBR and attempt to...
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Abstract Purpose The development of a preoperative anesthesia clinic (PAC) can reduce the number of surgical cases canceled on the day of surgery. However, there are only a few studies on the details of cancellations in the operating room. This study aimed to assess the incidence and reasons for surgical cases canceled from admission to the operating room to the start of surgery. ...
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Publication date: Available online 12 August 2020Source: Gait & PostureAuthor(s): Tishya A.L. Wren, Li-Shan Chou, Thomas Dreher
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ObjectivesThis study sought to investigate the association between occupational injury and subsequent risk of suicide in Korea.MethodsWe linked compensation data for 775 537 workers injured at work during 2003–2014 with National Death Registry through 2015. Suicide among injured workers was compared with the economically active population in Korea separately for men and women by calculating SMRs, with 95% CIs.ResultsInjured workers showed higher mortality from suicide for both men (SMR=2.22, 95%...
ObjectivesPeople who have experienced a work-related injury can experience further work injuries over time. This study examines predictors of subsequent work-related injuries over 24 months among a cohort of injured workers.MethodsParticipants were those recruited to the earlier Prospective Outcomes of Injury Study (POIS) who had a work-related injury (the ‘sentinel’ injury). Data from POIS participant interviews were combined with administrative data from the Accident Compensation Corporation (New...
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Publication date: Available online 12 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Stefano Negrini, Sabrina Donzelli, Alberto Negrini, Alessandra Negrini, Michele Romano, Fabio Zaina
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Publication date: Available online 12 August 2020Source: Sleep MedicineAuthor(s): Abdelkrim Janati Idrissi, Abdelaziz Lamkaddem, Abdelilah Benouajjit, Manar El bouaazzaoui, Farah El Houari, mohammed Alami, Sanae Labyad, Abderrahman Chahidi, Meryem Benjelloun, Samira Rabhi, Najib Kissani, Benaissa Zarhbouch, Reda Ouazzani, Fouzia Kadiri, Rachid Alouane, Mohamed Elbiaze, Said Boujraf, Samira El Fakir, Zouhayr Souirti
Publication date: Available online 12 August 2020Source: Sleep MedicineAuthor(s): Hiroshi Kataoka, Keigo Saeki, Norio Kurumatani, Kazuma Sugie, Kenji Obayashi
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