Objective The number of diagnosed fatal encephalitis in humans caused by the classical Borna disease virus (BoDV‐1) is increasingly recognized, ever since it was proven that BoDV‐1 can cause human infections. However, awareness for this entity is low and a specific imaging pattern has not yet been identified. We therefore provide the first comprehensive description on the morphology of human BoDV‐1 encephalitis with histopathological verification of imaging abnormalities. Methods In an institutional...
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The rebound effect after stopping treatment with denosumab may be associated with rapid loss of the gains in bone mineral density achieved with treatment, high levels of bone remodeling markers, the occurrence...
Hemangioma is a benign tumor made up of blood vessels and typically occurs as a slightly elevated purplish or reddish area of skin. Hemangioma is mostly found superficially; subcutaneous hemangioma in the nasa...
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A 93‐year‐old woman was admitted with a 10‐day history of cough and prostration. Thoracic computed tomography revealed extensive ground‐glass opacities in both the lungs. The polymerase chain reaction test of sputum for severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2) was positive. She was treated with antiviral agents and steroid pulse therapy. However, her oxygen saturation gradually declined, and she died 10 days after hospitalization. The most important autopsy finding was fuzzily...
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Surgical Infections, Ahead of Print.
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Summary Acromioclavicular joint injuries are commonly encountered in the setting of shoulder trauma. Knowledge of the anatomy and biomechanics of the joint, grading of joint injuries, and understanding the capabilities and limitations of different radiological modalities will help in selecting the best management option and outcomes for affected patients.
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Abstract It is still not known whether the oscillation in heart rate (HR) induced by sleep‐disordered breathing (SDB) in patients with heart failure entails significant chronotropic effects. We hypothesised that since cyclical changes in ventilation and arterial blood gases during SDB affect HR through multiple and complexly interacting mechanisms characterised by large inter‐subject variability, chronotropic effects may change from patient to patient. A total of 42 patients with moderate‐to‐severe...
Impact of obstructive sleep apnoea on cognitive function in multiple sclerosis: A longitudinal study
Abstract Cognitive impairment (CI) and fatigue are common in people with multiple sclerosis (MS), with well‐known profound effects on quality of life. Sleep disorders, including obstructive sleep apnoea (OSA), are also common in MS patients. The presence of CI has previously been shown to strongly correlate with OSA diagnosed using polysomnography in MS. Treatment of OSA has not previously been investigated as a potential modality to improve cognition in MS patients. Therefore, we sought to investigate...
Abstract Continuous positive airway pressure (CPAP) and different types of non‐invasive ventilation (NIV) have been studied in obesity hypoventilation syndrome such as bi‐level PAP with back‐up rate (BPAP‐BUR), BPAP without BUR, and the new hybrid devices that target a pre‐set volume by adjustment of pressure support (VT‐PS). Although several studies have compared one PAP intervention with the other, none has compared all four in a head‐to‐head design, which formed the basis of this network meta‐analysis....
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Oncogenesis, Published online: 13 August 2020; doi:10.1038/s41389-020-00257-zTargeting PD-L1 in non-small cell lung cancer using CAR T cells
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Horm Metab Res 2020; 52: 551-552DOI: 10.1055/a-1217-1529About 3000 thousand years ago Marcus Aurelius said: “Time is a sort of river of passing events, and strong is its current; no sooner is a thing brought to sight than it is swept by and another takes its place, and this too will be swept away…” 1.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Abstract | Full text
Horm Metab Res 2020; 52: 607-613DOI: 10.1055/a-1212-8803Lack of routine fresh or frozen tissue is a barrier to widespread transcriptomic analysis of adrenal cortical tumors and an impediment to translational research in endocrinology and endocrine oncology. Our group has previously pioneered the use of targeted amplicon-based next-generation sequencing for archival formalin-fixed paraffin-embedded (FFPE) adrenal tissue...
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Abstract As a follow‐up to the re‐evaluation of starch sodium octenyl succinate (SSOS; E 1450), the Panel on Food Additives and Flavourings (FAF) was requested to assess the safety of SSOS (E 1450) when used in food for infants below 16 weeks of age for food categories 13.1.5.1 and 13.1.1 and to address the data gaps identified during the re‐evaluation of the SSOS (E 1450). The process involved the publication of a call for data. The Panel considered it feasible to amend the specifications based...
Abstract The European Commission requested the EFSA Panel on Plant Health to prepare and deliver risk assessments for commodities listed in Commission Implementing Regulation EU/2018/2019 as ‘High risk plants, plant products and other objects’. This Scientific Opinion covers all plant health risks posed by unrooted cuttings of Jasminum polyanthum produced in a protected environment (greenhouse) that are imported from Israel, taking into account the available scientific information, including the...
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Facial Plast SurgDOI: 10.1055/s-0040-1714666Irregularities of the nasal dorsum or tip are a potential risk after rhinoplasty. Patients with thin skin are considered to be at a higher risk of these irregularities. Different materials and grafts to address areas that may result in a contour irregularity postoperatively include diced or crushed cartilage, temporalis fascia, fascia lata, and AlloDerm. We describe a new graft, the supracrural ligament graft, which can be used to camouflage or add bulk...
Facial Plast SurgDOI: 10.1055/s-0040-1713808The aim of the study is to: (1) evaluate national trends in care of facial paralysis, namely Bell's palsy, patients to identify the types of treatments patients are receiving and treatment gaps and (2) identify if newer, more complex surgical therapies published in the literature are being employed. Data were collected from the MarketScan Commercial Claims and Encounters Database by Truven Health. From the database, all inpatient and outpatient claims with...
Facial Plast SurgDOI: 10.1055/s-0040-1714264This study demonstrates that the trend of how rhytidectomy is valued can be used to determine not only the pricing of this good but also how receptive developing economic markets are to the export of cosmetic facial plastic surgery. This study seeks to analyze and compare the value of rhytidectomy in an established market and an emerging market. A cross-sectional survey was administered through public online forums to 162 casual observers in the United...
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