Abstract Backgorund It is known that omalizumab(OMA) is an effective and safe treatment option in the treatment of chronic spontaneous urticaria (CSU). In the literature, there are vary studies about effect of OMA treatment in CSU such as different response rates to treatment, different dose / time regime and different relapse rates after treatment. Objectives To investigate the evaluate the effect of at least 1 year continuous omalizumab treatment on relapse in CSU patients. Results...
Abstract Bone is the fourth most common site of melanoma metastasis after lung, liver and brain. Melanoma bone metastases typically occur in patients who already have widespread metastases in other organs. Current available approaches for bone metastases from melanoma include chemotherapy, radiotherapy, biological therapy, combination therapy and surgery. In this narrative review we describe the management of patients affected by melanoma bone metastases, discussing the diagnostic and treatment...
Abstract Low‐level laser therapy (LLLT) is used to treat androgenetic alopecia (AGA). The therapeutic effect of LLLT on AGA has been evaluated; however, there is a paucity of studies that investigated device‐ and usage‐related factors that may influence the effect of LLLT on hair regrowth. The literature was systematically searched to identify eligible studies; PubMed, Scopus, EMBASE and clinicaltrials.gov databases were searched on April 30th, 2020. Eligible studies were randomized trials that...
Abstract Ibrutinib is a Burton tyrosine kinase inhibitor (BTKi) approved for the treatment of several hematologic malignancies. Analyze skin adverse events (SAE). All the patients treated with Ibrutinib featuring cutaneous adverse events were selected. Twenty five patients were retrieved with a median interval between Ibrutinib start and SAE time of onset of 120 days. Most common SAE observed involved hairs and nails. Eczematous reaction and leucocytoclastic vasculitis were also detected. One patient...
Abstract Intralesional 5‐ fluorouracil (IL5‐FU) has been used off‐label for warts treatment; however its use was limited by intense pain. Combination treatment can offer a robust therapeutic effect. Was to assess the therapeutic efficacy, safety and tolerability of microneedling vs its combination with 5‐FU solution vs IL5‐FU in the treatment of plantar warts. Patients and Methods Ninety Patients with plantar warts were divided randomly into three groups each containing 30 patients. Group...
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