Abstract Purpose of Review Chronic foot pain constitutes a large portion of the chronic pain burden in the overall population. Plantar fasciitis is one of the most common and most easily identifiable causes of chronic foot pain. The syndrome has been estimated to cause 11 to 15% of foot pain visits, requiring professional care. Moreover, studies have suggested that 1 in 10 people will develop plantar fasciitis at some point in...
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The original version of this article unfortunately contained mistakes in Methods and Acknowledgements sections.
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Abstract Purpose of Review Cytolytic vaginosis is a controversial condition that some clinicians have traditionally included as a potential cause of vulvovaginal symptoms despite the lack of scientific evidence. Recent Findings Recent articles have focused on the evaluation of patients once they carry the diagnosis of cytolytic vaginosis,...
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Most of the genomic studies in plants and animals have used additive models for studying genetic parameters and prediction accuracies. In this study, we used genomic models with additive and nonadditive effects to analyse the genetic architecture of growth and wood traits in an open-pollinated (OP) population of Eucalyptus pellita. We used two progeny trials consisting of 5742 trees from 244 OP families to estimate genetic parameters and to test genomic prediction accuracies of three growth traits...
Tue Aug 11, 2020 23:28
Distant hybridization between the sea urchin Heliocidaris crassispina (♀) and the sea urchin Strongylocentrotus intermedius (♂) was successfully performed under laboratory conditions. A new variety of hybrid sea ...
Tue Aug 11, 2020 03:00
Under the threat of climate change populations can disperse, acclimatise or evolve in order to avoid fitness loss. In light of this, it is important to understand neutral gene flow patterns as a measure of dis...
Mon Aug 10, 2020 03:00
When survival over generations is the end game, researchers say it makes sense to undervalue long shots that could be profitable and overestimate the likelihood of rare bad outcomes.
Tue Aug 11, 2020 23:33
Scientists have discovered that the larynx, or voice box, of primates is significantly larger relative to body size, has greater variation, and is under faster rates of evolution than in other mammals.
Tue Aug 11, 2020 21:29
Most close relatives of birds neared the potential for powered flight but few crossed its thresholds
New research has resulted in an updated evolutionary tree of early birds and their closest relatives to reconstruct powered flight potential, showing it evolved at least three times. Many ancestors of the closest bird relatives neared the thresholds of powered flight potential, suggesting broad experimentation with wing-assisted locomotion before flight evolved.
Tue Aug 11, 2020 19:02
Summary Although immune checkpoint inhibitors have improved the survival of small cell lung cancer (SCLC) patients, their efficacy in SCLC patients who relapsed after systemic chemotherapy is unclear. This retrospective study aimed to investigate the utility of treatment with atezolizumab plus carboplatin and etoposide in SCLC patients previously treated with platinum-based chemotherapy. We retrospectively screened consecutive eight SCLC patients who received atezolizumab plus...
Tue Aug 11, 2020 03:00
Publication date: Available online 10 August 2020Source: Journal of VoiceAuthor(s): Marina Englert, Livia Lima, Ben Barsties v. Latoszek, Mara Behlau
Tue Aug 11, 2020 22:20
Background. Fulminant necrotising amoebic colitis (FulNAC) is an uncommon and grave complication of a very common infectious disease widely prevalent in tropical countries. In most of the cases reported, only a segment of large bowel was gangrenous. The involvement of the whole of the large bowel, as in our case, is very rare and has very high mortality ranging from 55% to 100%. Case Summary. A 50-year-old gentleman presented with an acute abdomen with a history of crampy abdominal pain and passage...
Tue Aug 11, 2020 17:35
Chryseobacterium gleum is a lactose nonfermenting Gram-negative bacillus (NFGNB) found in soil, plants, and some water sources but rarely implicated as a human pathogen. Its scarcity in the medical literature and resistance to numerous broad-spectrum antibiotics such as carbapenems, cephalosporins, and beta-lactam/lactamase inhibitors pose a diagnostic and therapeutic challenge. We present the first reported case, to the best of our knowledge, of sepsis from central line-associated blood stream infection...
Tue Aug 11, 2020 12:20
Gasping during cardiac arrest is associated with favourable neurological outcomes for out-of-hospital cardiac arrest. Moreover, while extracorporeal cardiopulmonary resuscitation (ECPR) performed for refractor...
Mon Aug 10, 2020 03:00
ObjectivesThe natural history of coal workers’ pneumoconiosis (CWP) after cessation of exposure remains poorly understood.MethodsWe characterised the development of and progression to radiographic progressive massive fibrosis (PMF) among former US coal miners who applied for US federal benefits at least two times between 1 January 2000 and 31 December 2013. International Labour Office classifications of chest radiographs (CXRs) were used to determine initial and subsequent disease severity. Multivariable...
Tue Aug 11, 2020 19:08
Publication date: Available online 11 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Alison M. Cogan, Bridget Smith, Theresa L. Bender Pape, Trudy Mallinson, Blessen C. Eapen, Joel Scholten
Tue Aug 11, 2020 19:00
Publication date: Available online 10 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Jooyeon Jamie Im, Jungyoon Kim, Hyeonseok Jeong, Jin Kyoung Oh, Suji Lee, In Kyoon Lyoo, Yong-An Chung, Sujung Yoon
Tue Aug 11, 2020 19:00
Publication date: Available online 10 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Stefania Fatone, Sara Jerousek, Billie C.S. Slater, Anne Deutsch, Sherri L. LaVela, Michelle Peterson, Nicole T. Soltys, Vari McPherson, Allen W. Heinemann
Tue Aug 11, 2020 19:00
COVID-19 pandemic is an obstacle for all health systems, especially in African countries. This paper shows how plastic surgery teams can adapt human resources and an efficient approach to provide the best care to our patients in this troubled time.
Tue Aug 11, 2020 03:00
Multi and extensively drug-resistant (MDR and XDR), Pseudomonas aeruginosa (P. aeruginosa) and Acinetobacter baumannii (A. baumannii) are two main causative agents of nosocomial infections leading to increased mo...
Mon Aug 10, 2020 03:00
The sulfur amino acid (SAA) cysteine is positively related, whereas polyunsaturated fatty acids (PUFAs) are inversely related to activity of the lipogenic enzyme stearoyl-CoA desaturase (SCD). High SCD activit...
Mon Aug 10, 2020 03:00
The potential use of symbiotic bacteria for the control of mosquito-borne diseases has attracted the attention of scientists over the past few years. Culiseta longiareolata is among the medically important mosqui...
Mon Aug 10, 2020 03:00
Abstract In recent decades, nanomaterials have been extensively investigated for many applications. Composites doped with different metal nanoparticles have been suggested as effective shielding materials to replace conventional lead-based materials. The use of concretes as structural and radiation protective material has been influenced by the addition of nanomaterials. Several elements with high atomic number and density, such as lead, bismuth, and tungsten, have the potential...
Tue Aug 11, 2020 03:00
Publication date: Available online 11 August 2020Source: CortexAuthor(s): Patrycja Kałamała, Michał Ociepka, Adam Chuderski
Tue Aug 11, 2020 18:07
Publication date: Available online 11 August 2020Source: CortexAuthor(s): Florian Bublatzky, Pedro Guerra, Georg W. Alpers
Tue Aug 11, 2020 18:07
Publication date: Available online 10 August 2020Source: CortexAuthor(s): Christian N.L. Olivers, Pieter R. Roelfsema
Tue Aug 11, 2020 18:07
Publication date: Available online 10 August 2020Source: CortexAuthor(s): Raffaella Migliaccio, Delphine Tanguy, Arabella Bouzigues, Idil Sezer, Bruno Dubois, Isabelle Le Ber, Bénédicte Batrancourt, Valérie Godefroy, Richard Levy
Tue Aug 11, 2020 18:07
Publication date: Available online 10 August 2020Source: CortexAuthor(s): Mira Didic, Virginia Aglieri, Eve Tramoni-Nègre, Lucas Ronat, Isabelle Le Ber, Mathieu Ceccaldi, Pascal Belin, Olivier Felician
Tue Aug 11, 2020 18:07
Abstract The second messenger cyclic adenosine monophosphate (cAMP) regulates numerous functions in both benign melanocytes and melanoma cells. cAMP is generated from two distinct sources, transmembrane and soluble adenylyl cyclases (tmAC and sAC, respectively) and is degraded by a family of proteins called phosphodiesterases (PDEs). cAMP signaling can be regulated in many different ways and can lead to varied effects in melanocytes. It was recently revealed that distinct cAMP signaling pathways...
Mon Aug 10, 2020 21:49
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