Antibiotics, Vol. 9, Pages 124: Actinomycosis of the Tongue: A Case Report and Review of Literature Antibiotics doi: 10.3390/antibiotics9030124 Authors: Fiorella D’Amore Roberto Franchini Laura Moneghini Niccolò Lombardi Giovanni Lodi Andrea Sardella Elena M. Varoni Background: Actinomycosis of the tongue is an uncommon, suppurative infection of lingual mucosa, caused by actinomyces. The clinical diagnosis may present serious difficulties because of its ability to mimic...
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Antioxidants, Vol. 9, Pages 241: Nitrates/Nitrites in Food—Risk for Nitrosative Stress and Benefits Antioxidants doi: 10.3390/antiox9030241 Authors: Karwowska Kononiuk In the context of impact on human health, nitrite/nitrate and related nitrogen species such as nitric oxide (NO) are a matter of increasing scientific controversy. An increase in the content of reactive nitrogen species may result in nitrosative stress—a deleterious process, which can be an important mediator...
Antioxidants, Vol. 9, Pages 240: Effects of Bisphenol A on Oxidative Stress in the Rat Brain Antioxidants doi: 10.3390/antiox9030240 Authors: Keiko Kobayashi Yanchen Liu Hiroshi Ichikawa Shigekazu Takemura Yukiko Minamiyama We investigated the effect of bisphenol A (BPA) on oxidative stress and tau-related proteins in adult rat brains. BPA (10 mg/L) was administered to rats for eight weeks through their drinking water. The reactive oxygen species (ROS) scavenging capacity...
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Atmosphere, Vol. 11, Pages 292: Simultaneous Measurements of Chemical Compositions of Fine Particles during Winter Haze Period in Urban Sites in China and Korea Atmosphere doi: 10.3390/atmos11030292 Authors: Park Wang Chong Lee Jang Song Kwak Borlaza Maeng Cosep Denna Chen Seo Bae Jang Choi Kim Park Ryu Park Hu Park We performed simultaneous measurements of chemical compositions of fine particles in...
Atmosphere, Vol. 11, Pages 293: North Atlantic Hurricane Winds in Warmer than Normal Seas Atmosphere doi: 10.3390/atmos11030293 Authors: Jill C. Trepanier Tropical cyclones devastate coastlines around the world. The United States and surrounding areas experienced catastrophic extreme events in recent hurricane seasons. Understanding extreme hurricanes and how they change in a warming ocean environment is of the utmost importance. This study makes use of the historical, positive relationship...
Atmosphere, Vol. 11, Pages 294: Measuring on-Road Vehicle Hot Running NOx Emissions with a Combined Remote Sensing–Dynamometer Study Atmosphere doi: 10.3390/atmos11030294 Authors: Robin Smit Daniel Kennedy This study explores the correlation in measured hot running NO/CO2 ratios by a remote sensing device (RSD) and dynamometer testing. Two large diesel cars (E4/E5) are tested on the dynamometer in hot running conditions using a new drive cycle developed for this study and then driven...
Atmosphere, Vol. 11, Pages 291: Climatology and Spatiotemporal Analysis of North Atlantic Rapidly Intensifying Hurricanes (1851–2017) Atmosphere doi: 10.3390/atmos11030291 Authors: Benedetto Trepanier In recent decades, the scientific ability to project tropical cyclone (TC) intensities and tracks has improved. Hurricanes undergoing the process of rapid intensification (RI) have created new barriers in formulating predictions of TC paths and peak velocities. Current research suggests...
Atmosphere, Vol. 11, Pages 290: Selected Metals in Urban Road Dust: Upper and Lower Silesia Case Study Atmosphere doi: 10.3390/atmos11030290 Authors: Rybak Wróbel Stefan Bihałowicz Rogula-Kozłowska In this study, urban road dust (URD) samples were collected in two populated agglomerations of Wrocław and Katowice (Lower and Upper Silesia) in Poland. Both the total concentrations of URD-bound Mn, Ni, Cu, Zn, As, Rb, Ba, Cr, Mg, and Al and concentrations of their water-soluble...
Atmosphere, Vol. 11, Pages 289: Development of Multiple Linear Regression for Particulate Matter (PM10) Forecasting during Episodic Transboundary Haze Event in Malaysia Atmosphere doi: 10.3390/atmos11030289 Authors: Samsuri Abdullah Nur Nazmi Liyana Mohd Napi Ali Najah Ahmed Wan Nurdiyana Wan Mansor Amalina Abu Mansor Marzuki Ismail Ahmad Makmom Abdullah Zamzam Tuah Ahmad Ramly Malaysia has been facing transboundary haze events every year in which the air contains...
Atmosphere, Vol. 11, Pages 288: Influence of Atmospheric Circulation on Aerosol and its Optical Characteristics in the Pearl River Delta Region Atmosphere doi: 10.3390/atmos11030288 Authors: Yilin Liu Jianjun He Xin Lai Chenwei Zhang Lei Zhang Sunling Gong Huizheng Che At present, few studies have focused on the impact of circulation patterns on aerosol pollution in the Pearl River delta region (PRD) region based on the objective circulation classification method. Based...
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Beverages, Vol. 6, Pages 18: Membrane-Based Operations in the Fruit Juice Processing Industry: A Review Beverages doi: 10.3390/beverages6010018 Authors: Carmela Conidi Roberto Castro-Muñoz Alfredo Cassano The fruit juice industry is one of the food sectors that has invested the most in the implementation of new technologies, such as non-thermal technologies. Among them, membrane processes are considered today well-established separation techniques to support the production and...
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Biology, Vol. 9, Pages 55: Metatranscriptomic and Metagenomic Analysis of Biological Diversity in Subglacial Lake Vostok (Antarctica) Biology doi: 10.3390/biology9030055 Authors: Gura Rogers A combined metatranscriptomic and metagenomic study of Vostok (Antarctica) ice core sections from glacial, basal, and lake water accretion ice yielded sequences that indicated a wide variety of species and possible conditions at the base of the glacier and in subglacial Lake Vostok. Few organisms...
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Biomedicines, Vol. 8, Pages 61: Cancer Vaccines and Oncolytic Viruses Exert Profoundly Lower Side Effects in Cancer Patients than Other Systemic Therapies: A Comparative Analysis Biomedicines doi: 10.3390/biomedicines8030061 Authors: Schirrmacher This review compares cytotoxic drugs, targeted therapies, and immunotherapies with regard to mechanisms and side effects. Targeted therapies relate to small molecule inhibitors. Immunotherapies include checkpoint inhibitory antibodies, chimeric...
Biomedicines, Vol. 8, Pages 60: Viral Vector-Based Melanoma Gene Therapy Biomedicines doi: 10.3390/biomedicines8030060 Authors: Altijana Hromic-Jahjefendic Kenneth Lundstrom Gene therapy applications of oncolytic viruses represent an attractive alternative for cancer treatment. A broad range of oncolytic viruses, including adenoviruses, adeno-associated viruses, alphaviruses, herpes simplex viruses, retroviruses, lentiviruses, rhabdoviruses, reoviruses, measles virus, Newcastle disease...
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Biomolecules, Vol. 10, Pages 460: Flagella and Swimming Behavior of Marine Magnetotactic Bacteria Biomolecules doi: 10.3390/biom10030460 Authors: Zhang Wu Marine environments are generally characterized by low bulk concentrations of nutrients that are susceptible to steady or intermittent motion driven by currents and local turbulence. Marine bacteria have therefore developed strategies, such as very fast-swimming and the exploitation of multiple directional sensing–response...
Biomolecules, Vol. 10, Pages 461: BioShell 3.0: Library for Processing Structural Biology Data Biomolecules doi: 10.3390/biom10030461 Authors: Joanna M. Macnar Natalia A. Szulc Justyna D. Kryś Aleksandra E. Badaczewska-Dawid Dominik Gront BioShell is an open-source package for processing biological data, particularly focused on structural applications. The package provides parsers, data structures and algorithms for handling and analyzing macromolecular sequences, structures...
Biomolecules, Vol. 10, Pages 458: Mesenchymal Cell Growth and Differentiation on a New Biocomposite Material: A Promising Model for Regeneration Therapy Biomolecules doi: 10.3390/biom10030458 Authors: Pomeraniec Benayahu Mesenchymal stem cells serve as the body’s reservoir for healing and tissue regeneration. In cases of severe tissue trauma where there is also a need for tissue organization, a scaffold may be of use to support the cells in the damaged tissue. Such a scaffold...
Biomolecules, Vol. 10, Pages 459: MBLinhibitors.com, a Website Resource Offering Information and Expertise for the Continued Development of Metallo--Lactamase Inhibitors Biomolecules doi: 10.3390/biom10030459 Authors: Cheng Thomas Joyner Kimble Sturgill Tran Vulcan Klinsky Orea Platt Cao Li Yang Yurkiewicz Fast Crowder In an effort to facilitate the discovery of new, improved inhibitors of the metallo--lactamases (MBLs), a...
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Biosensors, Vol. 10, Pages 25: Recyclable SERS-Based Immunoassay Guided by Photocatalytic Performance of Fe3O4@TiO2@Au Nanocomposites Biosensors doi: 10.3390/bios10030025 Authors: Yuanyuan Du Hongmei Liu Yiran Tian Chenjie Gu Ziqi Zhao Shuwen Zeng Tao Jiang A novel recyclable surface-enhanced Raman scattering (SERS)-based immunoassay was demonstrated and exhibited extremely high sensitivity toward prostate specific antigen (PSA). The immunoassay, which possessed a sandwich...
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Cancers, Vol. 12, Pages 703: Dual Targeting of the p38 MAPK-HO-1 Axis and cIAP1/XIAP by Demethoxycurcumin Triggers Caspase-Mediated Apoptotic Cell Death in Oral Squamous Cell Carcinoma Cells Cancers doi: 10.3390/cancers12030703 Authors: Chien Yang Yang Ku Lee Tsai Lin Yang Demethoxycurcumin (DMC) is a curcumin analogue with better stability and higher aqueous solubility than curcumin after oral ingestion and has the potential to treat diverse cancers, including...
Cancers, Vol. 12, Pages 701: A Comparative Analysis of Tumors and Plasma Circulating Tumor DNA in 145 Advanced Cancer Patients Annotated by 3 Core Cellular Processes Cancers doi: 10.3390/cancers12030701 Authors: Kristian Larson Radhamani Kannaiyan Ritu Pandey Yuliang Chen Hani M. Babiker Daruka Mahadevan Matched-targeted and immune checkpoint therapies have improved survival in cancer patients, but tumor heterogeneity contributes to drug resistance. Our study categorized...
Cancers, Vol. 12, Pages 702: STAT3 Mutation Is Associated with STAT3 Activation in CD30+ ALK− ALCL Cancers doi: 10.3390/cancers12030702 Authors: Emma I. Andersson Oscar Brück Till Braun Susanna Mannisto Leena Saikko Sonja Lagström Pekka Ellonen Sirpa Leppä Marco Herling Panu E. Kovanen Satu Mustjoki Peripheral T-cell lymphomas (PTCL) are a heterogeneous, and often aggressive group of non-Hodgkin lymphomas. Recent advances in the molecular and genetic characterization...
Cancers, Vol. 12, Pages 700: Identification of Deregulated Pathways, Key Regulators, and Novel miRNA-mRNA Interactions in HPV-Mediated Transformation Cancers doi: 10.3390/cancers12030700 Authors: Iris Babion Viktorian Miok Annelieke Jaspers Angelina Huseinovic Renske D. M. Steenbergen Wessel N. van Wieringen Saskia M. Wilting Next to a persistent infection with high-risk human papillomavirus (HPV), molecular changes are required for the development of cervical cancer....
Cancers, Vol. 12, Pages 699: The Capacity of High-Grade Serous Ovarian Cancer Cells to Form Multicellular Structures Spontaneously along Disease Progression Correlates with Their Orthotopic Tumorigenicity in Immunosuppressed Mice Cancers doi: 10.3390/cancers12030699 Authors: Alicia Goyeneche Michael-Anthony Lisio Lili Fu Rekha Srinivasan Juan Valdez Capuccino Zu-hua Gao Carlos Telleria Many studies have examined the biology, genetics, and chemotherapeutic response of...
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Cells, Vol. 9, Pages 732: Interferon- Stimulation Elicited by the Influenza Virus Is Regulated by the Histone Methylase Dot1L through the RIG-I-TRIM25 Signaling Axis Cells doi: 10.3390/cells9030732 Authors: Marcos-Villar Nistal-Villan Zamarreño Garaigorta Gastaminza Nieto Influenza virus infection increases the methylation of lysine 79 of histone 3 catalyzed by the Dot1L enzyme. The role of Dot1L against infections was highlighted by an increase of influenza A and...
Cells, Vol. 9, Pages 730: Enhanced Adipose Expression of Interferon Regulatory Factor (IRF)-5 Associates with the Signatures of Metabolic Inflammation in Diabetic Obese Patients Cells doi: 10.3390/cells9030730 Authors: Sindhu Kochumon Thomas Bennakhi Al-Mulla Ahmad : Interferon regulatory factors (IRFs) are emerging as the metabolic transcriptional regulators in obesity/type-2 diabetes (T2D). IRF5 is implicated with macrophage polarization toward the inflammatory...
Cells, Vol. 9, Pages 729: Human Peripheral Blood Gamma Delta T Cells: Report on a Series of Healthy Caucasian Portuguese Adults and Comprehensive Review of the Literature Cells doi: 10.3390/cells9030729 Authors: Sónia Fonseca Vanessa Pereira Catarina Lau Maria dos Anjos Teixeira Marika Bini-Antunes Margarida Lima Gamma delta T cells (Tc) are divided according to the type of Vδ and Vγ chains they express, with two major γδ Tc subsets...
Cells, Vol. 9, Pages 731: The Leader Position of Mesenchymal Cells Expressing N-Cadherin in the Collective Migration of Epithelial Cancer Cells doi: 10.3390/cells9030731 Authors: Inés Saénz-de-Santa-María Lucía Celada María-Dolores Chiara Understanding how heterogeneous cancer cell populations migrate collectively is of paramount importance to arrest metastasis. Here, we applied 3D culture-based approaches for in vitro modeling of the collective migration of squamous carcinoma...
Cells, Vol. 9, Pages 728: SIRT1 Alleviates LPS-Induced IL-1β Production by Suppressing NLRP3 Inflammasome Activation and ROS Production in Trophoblasts Cells doi: 10.3390/cells9030728 Authors: Sumi Park Jiha Shin Jeongyun Bae Daewon Han Seok-Rae Park Jongdae Shin Sung Ki Lee Hwan-Woo Park Emerging evidence indicates that aberrant maternal inflammation is associated with several pregnancy-related disorders such as preeclampsia, preterm birth, and intrauterine growth...
Cells, Vol. 9, Pages 727: GSK3β: A Master Player in Depressive Disorder Pathogenesis and Treatment Responsiveness Cells doi: 10.3390/cells9030727 Authors: Przemysław Duda Daria Hajka Olga Wójcicka Dariusz Rakus Agnieszka Gizak Glycogen synthase kinase 3β (GSK3β), originally described as a negative regulator of glycogen synthesis, is a molecular hub linking numerous signaling pathways in a cell. Specific GSK3β inhibitors have anti-depressant effects...
Cells, Vol. 9, Pages 726: Pro-Inflammatory Priming of Umbilical Cord Mesenchymal Stromal Cells Alters the Protein Cargo of Their Extracellular Vesicles Cells doi: 10.3390/cells9030726 Authors: Mairead Hyland Claire Mennan Emma Wilson Aled Clayton Oksana Kehoe Umbilical cord mesenchymal stromal cells (UCMSCs) have shown an ability to modulate the immune system through the secretion of paracrine mediators, such as extracellular vesicles (EVs). However, the culture conditions...
Cells, Vol. 9, Pages 725: Infectious Diseases and the Lymphoid Extracellular Matrix Remodeling: A Focus on Conduit System Cells doi: 10.3390/cells9030725 Authors: Fernanda N. Morgado Aurea Virgínia A. da Silva Renato Porrozzi The conduit system was described in lymphoid organs as a tubular and reticular set of structures compounded by collagen, laminin, perlecan, and heparin sulfate proteoglycan wrapped by reticular fibroblasts. This tubular system is capable of rapidly transport...
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Climate, Vol. 8, Pages 45: The Moist Adiabat, Key of the Climate Response to Anthropogenic Forcing Climate doi: 10.3390/cli8030045 Authors: Pinault A straightforward mechanism based on properties of the moist adiabat is proposed to construe the observed latitudinal and longitudinal distribution of the anthropogenic forcing efficiency. Considering precipitation patterns at the planetary scale, idealized environmental adiabats leading to low-pressure systems are deduced. When the climate...
Climate, Vol. 8, Pages 44: A Sensitivity Study of High-Resolution Climate Simulations for Greece Climate doi: 10.3390/cli8030044 Authors: Politi Sfetsos Vlachogiannis Nastos Karozis In the present study, the ability of the Advanced Weather Research and Forecasting numerical model (WRF-ARW) to perform climate regionalization studies in the topographically complex region of Greece, was examined in order to explore the possibility of a more reliable selection of physical...
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Diagnostics, Vol. 10, Pages 161: Mucopolysaccharidosis Type I Diagnostics doi: 10.3390/diagnostics10030161 Authors: Francyne Kubaski Fabiano de Oliveira Poswar Kristiane Michelin-Tirelli Ursula da Silveira Matte Dafne D. Horovitz Anneliese Lopes Barth Guilherme Baldo Filippo Vairo Roberto Giugliani Mucopolysaccharidosis type I (MPS I) is caused by the deficiency of α-l-iduronidase, leading to the storage of dermatan and heparan sulfate. There is a broad...
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Diversity, Vol. 12, Pages 103: Genetic Diversity and Population Structure in a Vitis spp. Core Collection Investigated by SNP Markers Diversity doi: 10.3390/d12030103 Authors: Bianchi Brancadoro De Lorenzis Single nucleotide polymorphism (SNP) genotyping arrays are powerful tools to measure the level of genetic polymorphism within a population. The coming of next-generation sequencing technologies led to identifying thousands and millions of SNP loci useful in assessing the...
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Foods, Vol. 9, Pages 346: Food Authentication: Techniques, Trends and Emerging Approaches Foods doi: 10.3390/foods9030346 Authors: Raúl González-Domínguez Multiple factors can directly influence the chemical composition of foods and, consequently, their organoleptic, nutritional and bioactive properties, including the geographical origin, the variety or breed, as well as the conditions of cultivation, breeding and/or feeding, among others [...]
Foods, Vol. 9, Pages 345: Toxicity and Synergistic Effect of Elsholtzia Ciliata Essential Oil and Its Main Components Against the Adult and Larval Stages of Tribolium Castaneum Foods doi: 10.3390/foods9030345 Authors: Liang Xu Yang Shao Zhou Wang Investigations have indicated that storage pests pose a great threat to global food security by damaging food crops and other food products derived from plants. Essential oils are proven to have significant effects on a...
Foods, Vol. 9, Pages 344: Mesopelagic Species and Their Potential Contribution to Food and Feed Security—A Case Study from Norway Foods doi: 10.3390/foods9030344 Authors: Anita R. Alvheim Marian Kjellevold Espen Strand Monica Sanden Martin Wiech The projected increase in global population will demand a major increase in global food production. There is a need for more biomass from the ocean as future food and feed, preferentially from lower trophic levels. In this study,...
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