Antibiotics, Vol. 9, Pages 127: Consumption of Antibiotics and Epidemiology of Clostridioides difficile in the European Union in 2016—Opportunity for Practical Application of Aggregate ECDC Data Antibiotics doi: 10.3390/antibiotics9030127 Authors: Estera Jachowicz Anna Różańska Monika Pobiega Mariusz Topolski Jadwiga Wójkowska-Mach Background: The most important pathomechanism of Clostridioides difficile infections (CDI) is post-antibiotic intestinal dysbiosis. CDI affects...
Thu Mar 19, 2020 02:00
Antioxidants, Vol. 9, Pages 251: Human Heme Oxygenase-1 Induced by Interleukin-6 via JAK/STAT3 Pathways Is a Tumor Suppressor Gene in Hepatoma Cells Antioxidants doi: 10.3390/antiox9030251 Authors: Chiang Chang Hsu Sung Feng Chao Juang Heme oxygenase-1 (HO-1) has several important roles in hepatocytes in terms of anti-inflammation, anti-apoptosis, and antioxidant properties. Interleukin-6 (IL-6) is a pleiotropic cytokine associated with liver regeneration and...
Thu Mar 19, 2020 02:00
Antioxidants, Vol. 9, Pages 250: Dietary Postbiotic Lactobacillus plantarum Improves Serum and Ruminal Antioxidant Activity and Upregulates Hepatic Antioxidant Enzymes and Ruminal Barrier Function in Post-Weaning Lambs Antioxidants doi: 10.3390/antiox9030250 Authors: Izuddin Humam Loh Foo Samsudin Postbiotics from Lactobacillus plantarum have been reported to improve growth performance, nutrient utilization, immune status and gut health in livestock. However, there...
Thu Mar 19, 2020 02:00
Antioxidants, Vol. 9, Pages 249: Characterization of Antioxidant Potential of Seaweed Extracts for Enrichment of Convenience Food Antioxidants doi: 10.3390/antiox9030249 Authors: Paola Antonia Corsetto Gigliola Montorfano Stefania Zava Irma Colombo Bergros Ingadottir Rosa Jonsdottir Kolbrun Sveinsdottir Angela Maria Rizzo In recent years, there has been a growing interest in natural antioxidants as replacements of synthetic compounds because of increased safety concerns...
Thu Mar 19, 2020 02:00
Antioxidants, Vol. 9, Pages 247: Germinated Riceberry Rice Enhanced Protocatechuic Acid and Vanillic Acid to Suppress Melanogenesis through Cellular Oxidant-Related Tyrosinase Activity in B16 Cells Antioxidants doi: 10.3390/antiox9030247 Authors: Teerapat Rodboon Seiji Okada Prasit Suwannalert The anti-melanogenic bioactivities of phytophenolic compounds have been well recognized. Riceberry rice contains a rich source of phenolic compounds that act as melanin inhibitors through...
Thu Mar 19, 2020 02:00
Antioxidants, Vol. 9, Pages 248: Effect of Acupuncture on Oxidative Stress Induced by Cerebral Ischemia-Reperfusion Injury Antioxidants doi: 10.3390/antiox9030248 Authors: Chao-Hsien Chen Ching-Liang Hsieh In this article, we review how acupuncture regulates oxidative stress to prevent ischemia–reperfusion injury. We electronically searched databases, including PubMed, Clinical Key and the Cochrane Library, from their inception to November 2019 by using the following medical...
Thu Mar 19, 2020 02:00
Atmosphere, Vol. 11, Pages 299: A Building-Block Urban Meteorological Observation Experiment (BBMEX) Campaign in Central Commercial Area in Seoul Atmosphere doi: 10.3390/atmos11030299 Authors: Moon-Soo Park Jae-Young Byon Baek-Jo Kim Woosuk Choi Kwang-Min Myung Sang-Hyun Lee Tae-Il Cho Jung-Hoon Chae Jae-Sik Min Minsoo Kang Joon-Bum Jee Sang-Heon Kim Chang-Rae Cho High-resolution meteorological information is essential for attaining sustainable and...
Thu Mar 19, 2020 02:00
Atmosphere, Vol. 11, Pages 300: Improving Ensemble Forecasting Using Total Least Squares and Lead-Time Dependent Bias Correction Atmosphere doi: 10.3390/atmos11030300 Authors: Aida Jabbari Deg-Hyo Bae Numerical weather prediction (NWP) models produce a quantitative precipitation forecast (QPF), which is vital for a wide range of applications, especially for accurate flash flood forecasting. The under- and over-estimation of forecast uncertainty pose operational risks and often encourage...
Thu Mar 19, 2020 02:00
Atmosphere, Vol. 11, Pages 298: Warm Rain in Southern West Africa: A Case Study at Savè Atmosphere doi: 10.3390/atmos11030298 Authors: Irene Reinares Martínez Jean-Pierre Chaboureau Jan Handwerker A warm-rain episode over southern West Africa is analyzed using unprecedented X-band radar observations from Savè, Benin and a Large-Eddy Simulation (LES) over a 240 × 240 km 2 domain. While warm rain contributes to 1% of the total rainfall in the LES, its...
Thu Mar 19, 2020 02:00
Biology, Vol. 9, Pages 56: Putative Protein Biomarkers of Escherichia coli Antibiotic Multiresistance Identified by MALDI Mass Spectrometry Biology doi: 10.3390/biology9030056 Authors: Telma de Sousa Didier Viala Laetitia Théron Christophe Chambon Michel Hébraud Patricia Poeta Gilberto Igrejas The commensal bacteria Escherichia coli causes several intestinal and extra-intestinal diseases, since it has virulence factors that interfere in important cellular processes....
Thu Mar 19, 2020 02:00
Biomedicines, Vol. 8, Pages 65: Identification of Aberrantly-Expressed Long Non-Coding RNAs in Osteoblastic Cells from Osteoporotic Patients Biomedicines doi: 10.3390/biomedicines8030065 Authors: Centofanti Santoro Marini Visconti Rinaldi Celi D’Arcangelo Novelli Orlandi Tancredi Tarantino Botta Osteoporosis (OP) is a multifactorial disease influenced by genetic, epigenetic, and environmental factors. One of the main causes of the bone homeostasis...
Thu Mar 19, 2020 02:00
Biomolecules, Vol. 10, Pages 472: The Impact of Mutant p53 in the Non-Coding RNA World Biomolecules doi: 10.3390/biom10030472 Authors: Di Agostino Long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), micro RNAs (miRNAs), and extracellular RNAs (exRNAs) are new groups of RNAs with regulation activities that have low or no protein-coding ability. Emerging evidence suggests that deregulated expression of these non-coding RNAs is associated with the induction and progression of diverse...
Thu Mar 19, 2020 02:00
Biomolecules, Vol. 10, Pages 471: Development of Novel 111-In-Labelled DOTA Urotensin II Analogues for Targeting the UT Receptor Overexpressed in Solid Tumours Biomolecules doi: 10.3390/biom10030471 Authors: Poret Desrues Bonin Pédard Dubois Leduc Modzelewski Decazes Morin Vera Castel Bohn Gandolfo Overexpression of G protein-coupled receptors (GPCRs) in tumours is widely used to develop GPCR-targeting radioligands for solid tumour imaging...
Thu Mar 19, 2020 02:00
Biomolecules, Vol. 10, Pages 470: Why Does Knocking Out NACHO, But Not RIC3, Completely Block Expression of α7 Nicotinic Receptors in Mouse Brain? Biomolecules doi: 10.3390/biom10030470 Authors: Anish Deshpande Remitha M. Vinayakamoorthy Brijesh K. Garg Jaya Prakash Thummapudi Gauri Oza Ketaki Adhikari Aayush Agarwal Parnika Dalvi Swetha Iyer Sarulatha Thulasi Raman Vijay Ramesh Akshitha Rameshbabu Alexandra Rezvaya Sneha Sukumaran Sweta Swaminathan...
Thu Mar 19, 2020 02:00
Biomolecules, Vol. 10, Pages 469: Detection of Pathognomonic Biomarker PrPSc and the Contribution of Cell Free-Amplification Techniques to the Diagnosis of Prion Diseases Biomolecules doi: 10.3390/biom10030469 Authors: Hasier Eraña Jorge M. Charco Ezequiel González-Miranda Sandra García-Martínez Rafael López-Moreno Miguel A. Pérez-Castro Carlos M. Díaz-Domínguez Adrián García-Salvador Joaquín Castilla Transmissible spongiform encephalopathies or prion diseases...
Thu Mar 19, 2020 02:00
Biosensors, Vol. 10, Pages 27: Graphene Oxide Bulk-Modified Screen-Printed Electrodes Provide Beneficial Electroanalytical Sensing Capabilities Biosensors doi: 10.3390/bios10030027 Authors: Samuel J. Rowley-Neale Dale A. C. Brownson Graham Smith Craig E. Banks We demonstrate a facile methodology for the mass production of graphene oxide (GO) bulk-modified screen-printed electrodes (GO-SPEs) that are economical, highly reproducible and provide analytically useful outputs. Through...
Thu Mar 19, 2020 02:00
Brain Sciences, Vol. 10, Pages 180: Systematic Review of Level 1 and Level 2 Screening Tools for Autism Spectrum Disorders in Toddlers Brain Sciences doi: 10.3390/brainsci10030180 Authors: Serena Petrocchi Annalisa Levante Flavia Lecciso The present study provides a systematic review of level 1 and level 2 screening tools for the early detection of autism under 24 months of age and an evaluation of the psychometric and measurement properties of their studies. Methods: Seven databases...
Thu Mar 19, 2020 02:00
Brain Sciences, Vol. 10, Pages 178: Insomnia Might Influence the Thickness of Choroid, Retinal Nerve Fiber and Inner Plexiform Layer Brain Sciences doi: 10.3390/brainsci10030178 Authors: Sahbaz Elbay Ozcelik Ozdemir Sleep may play a fundamental role in retinal regulation and the degree of retinal variables. However, no clinical study has investigated optical coherence tomography (OCT) parameters in patients with primary insomnia. All participants were evaluated with the...
Thu Mar 19, 2020 02:00
Brain Sciences, Vol. 10, Pages 179: Aspirin Resistance Affects Medium-Term Recurrent Vascular Events after Cerebrovascular Incidents: A Three-Year Follow-up Study Brain Sciences doi: 10.3390/brainsci10030179 Authors: Wiśniewski Filipska Sikora Kozera Background: The aim of this prospective, a three-year follow-up study, was to establish the role of high on-treatment platelet reactivity (HTPR) in predicting the recurrence of vascular events in patients after cerebrovascular...
Thu Mar 19, 2020 02:00
Brain Sciences, Vol. 10, Pages 177: Injury of Corticospinal Tract in a Patient with Subarachnoid Hemorrhage as Determined by Diffusion Tensor Tractography: A Case Report Brain Sciences doi: 10.3390/brainsci10030177 Authors: Chan-Hyuk Park Hyeong Ryu Chang-Hwan Kim Kyung-Lim Joa Myeong-Ok Kim Han-Young Jung We report diffusion tensor tractography (DTT) of the corticospinal tract (CST) in a patient with paresis of all four limbs following subarachnoid hemorrhage (SAH) with...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 729: Renal Tumors of Childhood—A Histopathologic Pattern-Based Diagnostic Approach Cancers doi: 10.3390/cancers12030729 Authors: Ooms Vujanić D’Hooghe Collini L’Herminé-Coulomb Vokuhl Graf Heuvel-Eibrink de Krijger Renal tumors comprise approximately 7% of all malignant pediatric tumors. This is a highly heterogeneous group of tumors, each with its own therapeutic management, outcome, and association with germline predispositions....
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 728: Predicting Glioblastoma Recurrence from Preoperative MR Scans Using Fractional-Anisotropy Maps with Free-Water Suppression Cancers doi: 10.3390/cancers12030728 Authors: Metz Molina-Romero Lipkova Gempt Liesche-Starnecker Eichinger Grundl Menze Combs Zimmer Wiestler Diffusion tensor imaging (DTI), and fractional-anisotropy (FA) maps in particular, have shown promise in predicting areas of tumor recurrence in glioblastoma....
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 725: Functional Blockade of E-Selectin in Tumor-Associated Vessels Enhances Anti-Tumor Effect of Doxorubicin in Breast Cancer Cancers doi: 10.3390/cancers12030725 Authors: Yoshihiro Morita Macall Leslie Hiroyasu Kameyama Ganesh L. R. Lokesh Norihisa Ichimura Rachel Davis Natalie Hills Nafis Hasan Roy Zhang Yuji Kondo David G. Gorenstein David E. Volk Inna Chervoneva Hallgeir Rui Takemi Tanaka Chemotherapy is a mainstay...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 726: Sea Hare Hydrolysate-Induced Reduction of Human Non-Small Cell Lung Cancer Cell Growth through Regulation of Macrophage Polarization and Non-Apoptotic Regulated Cell Death Pathways Cancers doi: 10.3390/cancers12030726 Authors: Marie Merci Nyiramana Soo Buem Cho Eun-Jin Kim Min Jun Kim Ji Hyeon Ryu Hyun Jae Nam Nam-Gil Kim Si-Hyang Park Yeung Joon Choi Sang Soo Kang Myunghwan Jung Min-Kyoung Shin Jaehee Han In-Seok Jang Dawon...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 724: Early Postoperative Circulating miR-483-5p Is a Prognosis Marker for Adrenocortical Cancer Cancers doi: 10.3390/cancers12030724 Authors: Maurine Oreglia Silviu Sbiera Martin Fassnacht Laurent Guyon Josiane Denis Justine Cristante Olivier Chabre Nadia Cherradi We have previously identified serum miR-483-5p as a preoperative diagnosis and prognosis biomarker for adrenocortical cancer (ACC). Here, we aimed to determine whether circulating...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 727: The Inhibitory Mechanisms of Tumor PD-L1 Expression by Natural Bioactive Gallic Acid in Non-Small-Cell Lung Cancer (NCLC) Cells Cancers doi: 10.3390/cancers12030727 Authors: Dong Young Kang Nipin Sp Eun Seong Jo Alexis Rugamba Dae Young Hong Hong Ghi Lee Ji-Seung Yoo Qing Liu Kyoung-Jin Jang Young Mok Yang Non-small-cell lung cancer (NSCLC) is the most common lung cancer subtype and accounts for more than 80% of all lung cancer...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 721: Anti-Cancer Potential of Two Plasma-Activated Liquids: Implication of Long-Lived Reactive Oxygen and Nitrogen Species Cancers doi: 10.3390/cancers12030721 Authors: Elena Griseti Nofel Merbahi Muriel Golzio Cold atmospheric plasma-exposed culture medium may efficiently kill cancer cells in vitro. Due to the complexity of the medium obtained after plasma exposure, less complex physiological liquids, such as saline solutions and saline buffers, are gathering...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 722: Integrative Analyses of Multilevel Omics Reveal Preneoplastic Breast to Possess a Molecular Landscape That is Globally Shared with Invasive Basal-Like Breast Cancer (Running Title: Molecular Landscape of Basal-Like Breast Cancer Progression) Cancers doi: 10.3390/cancers12030722 Authors: Zhenlin Ju Anjana Bhardwaj Matthew D. Embury Harpreet Singh Preethi H. Gunaratne Isabelle Bedrosian Jing Wang To characterize molecular changes accompanying...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 723: Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation Cancers doi: 10.3390/cancers12030723 Authors: Rocco Sciarrillo Anna Wojtuszkiewicz Irsan E. Kooi Leticia G. Leon Edwin Sonneveld Roland P. Kuiper Gerrit Jansen Elisa Giovannetti Gertjan J.L. Kaspers Jacqueline Cloos Glucocorticoid (GC) resistance is a crucial determinant of inferior...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 720: Liver Transplantation for Pediatric Liver Cancer Cancers doi: 10.3390/cancers12030720 Authors: Rakesh Sindhi Vinayak Rohan Andrew Bukowinski Sameh Tadros Jean de Ville de Goyet Louis Rapkin Sarangarajan Ranganathan Unresectable hepatocellular carcinoma (HCC) was first removed successfully with total hepatectomy and liver transplantation (LT) in a child over five decades ago. Since then, children with unresectable liver cancer have benefitted...
Thu Mar 19, 2020 02:00
Cancers, Vol. 12, Pages 719: Wee1 Inhibition Enhances the Anti-Tumor Effects of Capecitabine in Preclinical Models of Triple-Negative Breast Cancer Cancers doi: 10.3390/cancers12030719 Authors: Todd M. Pitts Dennis M. Simmons Stacey M. Bagby Sarah J. Hartman Betelehem W. Yacob Brian Gittleman John J. Tentler Diana Cittelly D. Ryan Ormond Wells A. Messersmith S. Gail Eckhardt Jennifer R. Diamond Triple-negative breast cancer (TNBC) is an aggressive subtype...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 757: Effect of Chemically Induced Hypoxia on Osteogenic and Angiogenic Differentiation of Bone Marrow Mesenchymal Stem Cells and Human Umbilical Vein Endothelial Cells in Direct Coculture Cells doi: 10.3390/cells9030757 Authors: Nguyen Canciani Cirillo Anastasia Peretti Mangiavini Bone is an active tissue where bone mineralization and resorption occur simultaneously. In the case of fracture, there are numerous factors required to facilitate bone...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 758: The Actin-Family Protein Arp4 Is a Novel Suppressor for the Formation and Functions of Nuclear F-Actin Cells doi: 10.3390/cells9030758 Authors: Yamazaki Gerhold Yamamoto Ueno Grosse Miyamoto Harata The crosstalk between actin and actin-related proteins (Arps), namely Arp2 and Arp3, plays a central role in facilitating actin polymerization in the cytoplasm and also in the nucleus. Nuclear F-actin is required for transcriptional regulation,...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 756: Murine Mesenchymal Stromal Cells Retain Biased Differentiation Plasticity Towards Their Tissue of Origin Cells doi: 10.3390/cells9030756 Authors: Ng Mak Popp Ng Mesenchymal stromal/stem cells (MSCs) reside in many human tissues and comprise a heterogeneous population of cells with self-renewal and multi-lineage differentiation potential, making them useful in regenerative medicine. It remains inconclusive whether MSCs isolated from different tissue...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 759: Total mRNA Quantification in Single Cells: Sarcoma Cell Heterogeneity Cells doi: 10.3390/cells9030759 Authors: Jonasson Andersson Dolatabadi Ghannoum Åman Ståhlberg Single-cell analysis enables detailed molecular characterization of cells in relation to cell type, genotype, cell state, temporal variations, and microenvironment. These studies often include the analysis of individual genes and networks of genes. The total amount of RNA also...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 755: Cell Stress Induced Stressome Release Including Damaged Membrane Vesicles and Extracellular HSP90 by Prostate Cancer Cells Cells doi: 10.3390/cells9030755 Authors: Takanori Eguchi Chiharu Sogawa Kisho Ono Masaki Matsumoto Manh Tien Tran Yuka Okusha Benjamin J. Lang Kuniaki Okamoto Stuart K. Calderwood Tumor cells exhibit therapeutic stress resistance-associated secretory phenotype involving extracellular vesicles (EVs) such as oncosomes...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 752: A Signaling Crosstalk between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival Cells doi: 10.3390/cells9030752 Authors: Annalisa Addante Cesáreo Roncero Nerea Lazcanoiturburu Rebeca Méndez Laura Almalé María García-Álvaro Peter ten Dijke Isabel Fabregat Blanca Herrera Aránzazu Sánchez During chronic liver disease, hepatic progenitor cells (HPC, oval cells in rodents) become activated, proliferate, and differentiate...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 754: Phenotyping of Rare CFTR Mutations Reveals Distinct Trafficking and Functional Defects Cells doi: 10.3390/cells9030754 Authors: Marjolein Ensinck Liesbeth De Keersmaecker Lise Heylen Anabela S. Ramalho Rik Gijsbers Ricard Farré Kris De Boeck Frauke Christ Zeger Debyser Marianne S. Carlon Background. The most common CFTR mutation, F508del, presents with multiple cellular defects. However, the possible multiple defects caused by many...
Thu Mar 19, 2020 02:00
Cells, Vol. 9, Pages 753: Understanding the Synergy of NKp46 and Co-Activating Signals in Various NK Cell Subpopulations: Paving the Way for More Successful NK-Cell-Based Immunotherapy Cells doi: 10.3390/cells9030753 Authors: Loris Zamai Genny Del Zotto Flavia Buccella Sara Gabrielli Barbara Canonico Marco Artico Claudio Ortolani Stefano Papa The NK cell population is characterized by distinct NK cell subsets that respond differently to the various activating stimuli....
Thu Mar 19, 2020 02:00
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