Related ArticlesClinicopathological significance of EGFR pathway gene mutations and CRTC1/3-MAML2 fusions in salivary gland mucoepidermoid carcinoma. Histopathology. 2020 Mar 04;: Authors: Morita M, Murase T, Okumura Y, Ueda K, Sakamoto Y, Masaki A, Kawakita D, Tada Y, Nibu KI, Shibuya Y, Inagaki H Abstract BACKGROUND: Mucoepidermoid carcinoma (MEC) is one of the most common salivary gland carcinomas. Epidermal growth factor receptor (EGFR) signaling...
Related ArticlesPrevalence of hearing loss and tinnitus in a group of adults with Human Immunodeficiency Virus. S Afr J Commun Disord. 2020 Feb 04;67(1):e1-e7 Authors: Millar A, Joubert K, Naude A Abstract BACKGROUND: The Human Immunodeficiency Virus (HIV) has become a global pandemic. With the improvement of antiretroviral (ARV) treatment regimens, life-expectancy of HIV-positive individuals has increased. HIV literature suggests that head and neck...
Related ArticlesSydney Facial Nerve Clinic: experience of a multidisciplinary team. ANZ J Surg. 2020 Mar 04;: Authors: Hayler R, Clark J, Croxson G, Coulson S, Hussain G, Ngo Q, Ch'ng S, Low TH Abstract BACKGROUND: The Sydney Facial Nerve Clinic (SFNC) is a multidisciplinary clinic established in 2015, consisting of surgeons (otolaryngologists, head and neck and plastics/reconstructive), physiotherapists and speech pathologists. METHODS:...
Related ArticlesOutcomes and toxicities following stereotactic ablative radiotherapy for pulmonary metastases in patients with primary head and neck cancer. Head Neck. 2020 Mar 04;: Authors: Pasalic D, Betancourt-Cuellar SL, Taku N, Ludmir EB, Lu Y, Allen PK, Tang C, Antonoff MB, Fuller CD, Rosenthal DI, Morrison WH, Phan J, Garden AS, Welsh JW, Chang JY, Liao Z, Erasmus JJ, Nguyen QN Abstract BACKGROUND: Metastatic head and neck cancers (HNCs) predominantly...
Related ArticlesInfluence of preoperative radiotherapy on head and neck free-flap reconstruction: Systematic review and meta-analysis. Head Neck. 2020 Mar 04;: Authors: Mijiti A, Kuerbantayi N, Zhang ZQ, Su MY, Zhang XH, Huojia M Abstract The effect of preoperative external radiotherapy (XRT) on head and neck free-flap reconstruction is still controversial. In this study, we aimed to determine the impact of preoperative XRT on the outcomes of head...
Related ArticlesThe Role of postoperative external beam radiotherapy for differentiated thyroid carcinoma: A Systematic review and meta-analysis. Head Neck. 2020 Mar 04;: Authors: Jacomina LE, Jacinto JKM, Co LBA, Yu KKL, Agas RAF, Co JL, Mejia MBA Abstract The indications for external beam radiotherapy (RT) in differentiated thyroid carcinomas (DTC) are still undefined. The objective of this study was to synthesize current evidence defining the...
Related ArticlesMiddle ear adenoma with neuroendocrine differentiation: Report of a rare case. Indian J Cancer. 2020 Jan-Mar;57(1):98-101 Authors: Yadav SK, Naeem R, Sharma A, Singh S, Sarin N, Pruthi SK Abstract Middle ear adenoma with neuroendocrine differentiation (MEA-ND) is also called as neuroendocrine adenoma. Neuroendocrine tumors are rarely seen in the head and neck region and are even more rare in the middle ear. Clinical and radiological...
Related ArticlesEfficacy and tolerability of nimotuzumab in combination with chemotherapy in recurrent and metastatic squamous cell carcinoma of head and neck at a cancer center in Northern India. Indian J Cancer. 2020 Jan-Mar;57(1):76-83 Authors: Yadav A, Goyal P, Agrawal CR, Bothra SJ, Jain P, Choudhury KD, Gupta SK, Sharma M, Bajaj R, Upadhyay A, Dash P, Doval DC Abstract Introduction: Squamous cell carcinoma of head and neck (SCCHN) account for...
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Related ArticlesTrends in aeroallergen sensitization in Germany - An analysis of 2919 serological data sets of a university ENT department. Acta Otolaryngol. 2020 Mar 04;:1-7 Authors: Gellrich D, Eder K, Englhard AS, Gröger M Abstract Background: Recently, population-based birth-cohort studies provided an insight into the allergic march during childhood.Aims: Our study aimed to investigate sensitization pattern until advanced age.Patients and methods:...
Related ArticlesMaintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells. EMBO Mol Med. 2020 Mar 04;:e11101 Authors: Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Fischer T, Walz S, Schülein-Völk C, Eilers U, Ade CP, Calzado MA, Orian A, Maric HM, Münch C, Rosenfeldt M, Eilers M, Diefenbacher ME Abstract The transcription factor ∆Np63 is a master regulator of epithelial cell identity and essential for the survival...
Related ArticlesDigital Workflow for Producing Oral Positioning Radiotherapy Stents for Head and Neck Cancer. J Prosthodont. 2020 Mar 03;: Authors: Bruno JS, Miranda-Silva W, Guedes VDS, Parahyba CJ, de Moraes FY, Fregnani ER Abstract Oral positioning radiotherapy stents are devices that protect healthy structures adjacent to the target volume of head and neck radiotherapy treatment, leading to reduced acute and chronic side effects. It is described...
Related ArticlesSuicide attempts in patients with head and neck cancer in Taiwan. Psychooncology. 2020 Mar 03;: Authors: Sun LM, Lin CL, Shen WC, Kao CH Abstract OBJECTIVE: We examined the risk of suicide attempts in patients with head and neck cancer (HNC) in comparison with that in the general population and in patients of other cancers (including all other cancers rather than HNC). METHODS: The definition of suicide attempt here is that...
Related ArticlesHSP105 expression in oral squamous cell carcinoma: correlation with clinicopathological features and outcomes. J Oral Pathol Med. 2020 Mar 03;: Authors: Arvanitidou S, Martinelli-Kläy CP, Samson J, Lobrinus JA, Dulguerov N, Lombardi T Abstract BACKGROUND: Heat shock proteins (HSPs) are released in response to stress situations, such as heat, inflammation, infection. They are also involved in the tumor cell proliferation and prevention...
Related ArticlesIncomplete Excision of Cutaneous Squamous Cell Carcinoma; Systematic Review of the Literature. Acta Derm Venereol. 2020 Mar 04;: Authors: Genders RE, Marsidi N, Michi M, Henny EP, Goeman JJ, van Kester MS Abstract The treatment of choice for cutaneous squamous cell carcinoma is complete surgical excision. Incomplete excision of cutaneous squamous cell carcinoma has an increased risk of local recurrence, deep subclinical progression,...
Related ArticlesChildhood Nasal Foreign Bodies: Analysis of 1724 Cases. Turk Arch Otorhinolaryngol. 2019 Dec;57(4):187-190 Authors: Hira İ, Tofar M, Bayram A, Yaşar M, Mutlu C, Özcan İ Abstract Objective: This study evaluates the characteristics of the foreign bodies removed from the nose, the treatment methods used, and the complications associated with the foreign body, and discusses the reports in the literature. Methods: Age, gender,...
Related ArticlesA Study on the Use of Massive Open Online Courses in Otorhinolaryngology After Graduation. Turk Arch Otorhinolaryngol. 2019 Dec;57(4):171-175 Authors: Eyigör H, Gürpınar E Abstract Objective: The use of massive open online courses (MOOCs) in medical education and postgraduate education is becoming more and more widespread across the world. A survey study was carried out in Turkey to collect information and raise awareness about the...
Related ArticlesAntimicrobial Activity of Garlic Derivatives on Common Causative Microorganisms of the External Ear Canal and Chronic Middle Ear Infections. Turk Arch Otorhinolaryngol. 2019 Dec;57(4):161-165 Authors: Uzun L, Dal T, Kalcıoğlu MT, Yürek M, Açıkgöz ZC, Durmaz R Abstract Objective: Today, antibiotic resistance is increasing and evolving into an important health problem. Therefore, it is important to research on alternative therapies...
Related ArticlesActive surveillance for patients with very low-risk thyroid cancer. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):175-182 Authors: Lohia S, Hanson M, Tuttle RM, Morris LGT Abstract Over the past 30 years in the United States, increasing identification of small thyroid nodules has led to a dramatic rise in the detection of small thyroid cancers, many of which are unlikely to progress to overt clinical disease. Because autopsy studies...
Related ArticlesHorizontal semicircular canal jam: Two new cases and possible mechanisms. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):163-167 Authors: Schubert MC, Helminski J, Zee DS, Cristiano E, Giannone A, Tortoriello G, Marcelli V Abstract Introduction: Benign paroxysmal positional vertigo (BPPV) of the horizontal semicircular canal (hSCC) can present with otoconia blocking its lumen (canalith jam), with signs and symptoms that make it...
Related ArticlesTemporal bone histopathology in MELAS syndrome. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):152-156 Authors: Handzel O, Ungar OJ, Lee DJ, Nadol JB Abstract Objectives: Describe the histopathology of the temporal bones in MELAS (myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) syndrome. The syndrome results from a known point mutation in mitochondrial DNA. Methods: Histopathology analysis of a pair...
Related ArticlesContemporary techniques in human otopathology and promise for the future. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):145-151 Authors: Nadol JB Abstract Contemporary histopathology of the ear is based on an evolution of equipment and histological techniques over the last 500 years, including the invention of the light microscope and protocols for fixation, embedment, sectioning, and staining of tissue samples, and visual documentation...
Related ArticlesPractices and perceptions of cognitive assessment for adults with age-related hearing loss. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):137-144 Authors: Raymond MJ, Lee AC, Schader LM, Moore RH, Raol NR, Vivas EX Abstract Objectives: To investigate the landscape of cognitive impairment (CI) screening for adults with age-related hearing loss (ARHL) among otolaryngologists and audiologists. To identify provider factors and patient...
Related ArticlesAge-related change of auditory functional connectivity in Human Connectome Project data and tinnitus patients. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):132-136 Authors: Minami SB, Oishi N, Watabe T, Wasano K, Ogawa K Abstract Background: We reported that tinnitus patients showed reduced levels of auditory functional connectivity (FC) in comparison with normal hearing control subjects, and that we succeeded in objective diagnosis...
Related ArticlesInner ear delivery: Challenges and opportunities. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):122-131 Authors: Szeto B, Chiang H, Valentini C, Yu M, Kysar JW, Lalwani AK Abstract Objectives: The treatment of inner ear disorders remains challenging due to anatomic barriers intrinsic to the bony labyrinth. The purpose of this review is to highlight recent advances and strategies for overcoming these barriers and to discuss promising...
Related ArticlesTemporal bone histopathology: Superior semicircular canal dehiscence. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):117-121 Authors: Lin BM, Reinshagen K, Nadol J, Quesnel AM Abstract Objectives: To present a histopathological case of a 91-year-old woman who was diagnosed with superior semicircular canal dehiscence postmortem. Methods: The patient was a registered donor with the National Temporal Bone Donor Program at...
Related ArticlesAutomated assessment of psychiatric disorders using speech: A systematic review. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):96-116 Authors: Low DM, Bentley KH, Ghosh SS Abstract Objective: There are many barriers to accessing mental health assessments including cost and stigma. Even when individuals receive professional care, assessments are intermittent and may be limited partly due to the episodic nature of psychiatric symptoms....
Related ArticlesEffects of thyroplasty implant stiffness on glottal shape and voice acoustics. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):82-89 Authors: Cameron BH, Zhang Z, Chhetri DK Abstract Objectives: Vocal fold (VF) stiffness and geometry are determinant variables in voice production. Type 1 medialization thyroplasty (MT), the primary surgical treatment for glottic insufficiency, changes both of these variables. Understanding the cause...
Related ArticlesPrognostic factors in laryngeal squamous cell carcinoma. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):74-81 Authors: Bradford CR, Ferlito A, Devaney KO, Mäkitie AA, Rinaldo A Abstract Background: The current treatment results of laryngeal squamous cell carcinoma still remain modest. Various prognostic factors have been investigated and need to be included in the management decision making. Methods: We reviewed the pertinent...
Related ArticlesSystematic review and meta-analysis of transoral laser microsurgery in hypopharyngeal carcinoma. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):66-73 Authors: Lane C, Rabbani R, Linton J, Taylor SM, Viallet N Abstract Background: Transoral laser microsurgery has been suggested as an alternative treatment modality for hypopharyngeal carcinoma. The purpose of this study is to systematically review the oncologic and functional outcomes...
Related ArticlesOrgan preservation following radiation therapy and concurrent intra-arterial low dose cisplatin infusion for advanced T2 and T3 laryngeal cancer: Long-term clinical results from a pilot study. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):55-65 Authors: Ono T, Tanaka N, Tanoue S, Miyata Y, Muraki K, Tsuji C, Ogo E, Aso T, Chitose SI, Shin B, Kakuma T, Etoh H, Hattori C, Abe T, Umeno H Abstract Background: This pilot study evaluated...
Related ArticlesElectronic tumor board presentations as the basis for the development of a head and neck cancer database. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):46-54 Authors: Rangabashyam M, Wee HE, Wang W, Mueller S, Karim KABA, Skanthakumar T, Hariraman B, Sommat K, Soong YL, Chua MLK, Tay G, Tan NC, Tan HK, Iyer NG Abstract Background: Multidisciplinary team meetings or tumor boards (TBs) form a pivotal component of oncology practice....
Related ArticlesA 3D printed smartphone adaptor for nasolaryngoscopy. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):31-36 Authors: Thompson D, Albarki H, Lodhia C, Fitzpatrick N Abstract Objective: The objective of this project is to create a three-dimensional (3D) printed smartphone adaptor for flexible nasolaryngoscopy (FNL) to provide an affordable alternative to commercial options and a better fit than generic telescope phone adaptors. ...
Related ArticlesA new office-based procedure for treatment of snoring: The S.I.Le.N.C.E. study. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):24-30 Authors: Friedman M, Gillespie MB, Shabdiz FA, Hiltzik DH, Meyer TA, Ahn J, Catalano PJ, Joseph NJ Abstract Objective: Demonstrate the safety and effectiveness of palatal foreshortening and stiffening in reducing snoring severity in nonobstructive sleep apnea (non-OSA) patients complaining of chronic...
Related ArticlesPrevalence and significance of cranial nerve imaging abnormalities in patients with hereditary neuropathies: Clinical implications at the skull base. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):11-18 Authors: Bartholomew RA, Zamani AA, Kim GS, Alyono JC, Steinert H, Fridman V, Sadjadi R, Jackler RK, Corrales CE Abstract Objective: To estimate the prevalence and significance of cranial nerve (CN) imaging abnormalities in patients...
Related ArticlesThe PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism. Mol Ther Oncolytics. 2020 Mar 27;16:238-249 Authors: McLaughlin M, Pedersen M, Roulstone V, Bergerhoff KF, Smith HG, Whittock H, Kyula JN, Dillon MT, Pandha HS, Vile R, Melcher AA, Harrington KJ Abstract Reovirus type 3 Dearing (reovirus) is a tumor-selective oncolytic virus currently under evaluation...
Related ArticlesAt-Risk Tackling Techniques in American Football. Orthop J Sports Med. 2020 Feb;8(2):2325967120902714 Authors: Stockwell DW, Blalock R, Podell K, Marco RAW Abstract Background: In American football, fewer fatalities and severe injuries have been seen annually since 1976, after data from 1971 through 1975 were retrospectively reviewed to better understand the mechanisms involved in catastrophic cervical spine injury and rules were...
Related ArticlesProsthetic rehabilitation of the geriatric oncologic rhinectomy patient utilizing a craniofacial implant-retained nasal prosthesis. Clin Case Rep. 2020 Feb;8(2):278-282 Authors: Rosen EB, Ahmed ZU, Huryn JM, Ganly I Abstract This clinical report describes the expeditious treatment of a geriatric patient with squamous cell carcinoma of the nose treated with total rhinectomy, craniofacial implant placement, and a nasal prosthesis.PMID:...
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