Abstract Background Tuberculosis remains a major health problem in the less developed nations and is now a major health problem in developed countries, owing to the emergence of human immunodeficiency virus (HIV) infection and (AIDS). However, despite the availability of effective chemotherapy, patient noncompliance with regimens is the most common reason for therapeutic failures. The aim of this study is to describe the cytological features of drug defaulters on lymph node fine‐needle aspiration...
Thu Mar 05, 2020 15:48
Abstract Perivascular epithelioid cell tumors (PEComas) are rare mesenchymal tumors with immunohistochemical co‐expression of melanocytic and myoid markers. Vaginal PEComas have been described in only nine cases so far. We describe the case of a 65‐year‐old female with a large growth in the left lateral vaginal wall. Biopsy imprint smears showed dispersed tumor cells with anisonucleosis, multinucleation, and bizarre forms, suggestive of a malignant tumor. Histopathology, however, showed perivascular...
Thu Mar 05, 2020 15:48
Publication date: Available online 4 March 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): S. Mumtaz, V. Sharma
Thu Mar 05, 2020 15:48
Publication date: Available online 4 March 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): F. Biglioli, D. Rabbiosi, F. Bolognesi, M. Cucurullo, M. Dessy, C. Ciardiello, V.M.A. Battista, F. Tarabbia, G. Dell’Aversana Orabona, C. Marchetti, F. Allevi
Thu Mar 05, 2020 15:48
Publication date: Available online 4 March 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): J. Wu, Q. Fang, F. Liu, X. Zhang
Thu Mar 05, 2020 15:48
Opinion statement Opioids are the gold standard for the treatment of cancer-related pain. Preclinical studies have associated opioids with cancer progression and overall survival. In mice models, opioids have been shown to possess pro-tumor activity secondary to immunosuppression, migration of tumor cells, increased activity of vascular endothelial growth factor receptors, and angiogenesis leading to tumor progression. In contrast, opioids have also been associated with having...
Thu Feb 20, 2020 02:00
Opinion statement The last few years have seen unprecedented advances in treatment options for patients diagnosed with acute lymphoblastic leukaemia (ALL) in adulthood. New targeted drug therapies have been shown in randomised trials to offer significant survival improvements above standard-of-care (SoC) for relapsed disease, whilst being relatively well tolerated. Chimeric antigen receptor T cell therapy (CAR-T) has offered spectacular promise amongst the young adult population,...
Thu Feb 20, 2020 02:00
Abstract Objective Perfusion and oxygenation are critical parameters of muscle metabolism in health and disease. They have been both the target of many studies, in particular using Near‐Infrared Spectroscopy (NIRS). However, difficulties with quantifying NIRS signals have limited a wide dissemination of the method to the clinics. Our aim was to investigate whether clinical Multispectral Optoacoustic Tomography (MSOT), could enable the label‐free imaging of muscle perfusion and oxygenation...
Thu Mar 05, 2020 15:47
Superficial photothermal laser ablation (SPLA) may be useful as a therapeutic approach producing a depth of injury that is sufficient to eliminate mucosal lesion but not deep enough to induce thermal effects in deeper tissue layers. The purpose of this preliminary study is twofold: (1) to describe design steps of a fiber probe capable of delivering a tightly focused laser beam, including Monte‐Carlo based simulations, and (2) to complete the initial testing of the probe in a sheep esophagus model,...
Thu Mar 05, 2020 15:47
Publication date: April 2020Source: European Journal of Cancer, Volume 129Author(s): Parvin Zamani, Manouchehr Teymouri, Amin Reza Nikpoor, Jamshid Gholizadeh Navashenaq, Zahra Gholizadeh, Shahrzad Amiri Darban, Mahmoud Reza Jaafari
Thu Mar 05, 2020 15:46
Publication date: April 2020Source: European Journal of Cancer, Volume 129Author(s): Akihito Kawazoe, Kensei Yamaguchi, Hisateru Yasui, Yuji Negoro, Mizutomo Azuma, Kenji Amagai, Hiroki Hara, Hideo Baba, Masahiro Tsuda, Hisashi Hosaka, Hisato Kawakami, Takashi Oshima, Yasushi Omuro, Nozomu Machida, Taito Esaki, Kazuhiro Yoshida, Tomohiro Nishina, Yoshito Komatsu, Shi R. Han, Shinichi Shiratori
Thu Mar 05, 2020 15:46
Abstract We present the historical review and current state of the histopathological classifications and terminology of laryngeal precursor lesions. Attention to recent genetic findings is also presented; although in need of additional confirmation, these raise possibility for early detection of patients at risk of dysplasia progression. Although a number of identified genetic alterations with a promising diagnostic and prognostic value are emerging, none of the known genetic alterations...
Thu Mar 05, 2020 02:00
Publication date: Available online 5 March 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Hanwen Chu, Feifei Xu, Xin Xu
Thu Mar 05, 2020 15:43
Related ArticlesPostoperative Non-Pathological Fever Following Posterior Cervical Fusion Surgery : Is Laminoplasty a Better Preventive Method than Laminectomy? J Korean Neurosurg Soc. 2020 Mar 05;: Authors: Lee S, Jung SK, Kim HB, Roh SW, Jeon SR, Park JH Abstract Objective: To analyze the incidence and characteristics of delayed postoperative fever in posterior cervical fusion using cervical pedicle screws (CPS). Methods: This study analyzed...
Thu Mar 05, 2020 15:41
Related ArticlesCan Computed Tomographic Angiography Be Used to Predict Who Will Not Benefit from Endovascular Treatment in Patients with Acute Ischemic Stroke? The CTA-ABC Score. J Korean Neurosurg Soc. 2020 Mar 05;: Authors: Kwak HS, Park JS Abstract Objective: The objective of this study was to develop a score to predict patients with acute ischemic stroke (AIS) who will not benefit from endovascular treatment (EVT) using computed tomographic angiography...
Thu Mar 05, 2020 15:41
Related ArticlesEndovascular Treatment of Traumatic Arteriovenous Fistula in Young Adults with Pulsatile Tinnitus. J Korean Neurosurg Soc. 2020 Mar 05;: Authors: Kim HS, Song JH, Oh JK, Ahn JH, Kim JH, Chang IB Abstract Traumatic arteriovenous fistulas (AVFs) involving the external carotid artery are exceedingly rare in young adults. Since an AVF is the most common life-threatening cause for pulsatile tinnitus (PT), meticulous evaluation and treatment...
Thu Mar 05, 2020 15:41
39 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 15:39
39 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 13:34
Foreword. In this Journal feature, information about a real patient is presented in stages (boldface type) to an expert clinician, who responds to the information by sharing relevant background and reasoning with the reader (regular type). The authors’ commentary follows. Stage. A 64-year-old man…
Thu Mar 05, 2020 02:00
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 15:32
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 13:35
Publication date: May 2020Source: International Immunopharmacology, Volume 82Author(s): Haoming Zhou, Jie Sun, Weizhe Zhong, Xiongxiong Pan, Cunming Liu, Feng Cheng, Ping Wang, Zhuqing Rao
Thu Mar 05, 2020 15:31
Publication date: May 2020Source: International Immunopharmacology, Volume 82Author(s): Yu Jin, Xing Qin
Thu Mar 05, 2020 15:31
Publication date: May 2020Source: International Immunopharmacology, Volume 82Author(s): Shanshan Yu, Guoqing Zhao, Fanglei Han, Wenzhao Liang, Yuan Jiao, Zinan Li, Longyun Li
Thu Mar 05, 2020 15:31
לקריאת המאמר במלאת חמישים שנה ללכתם של הסופר ש"י עגנון וחוקר הלשון חנוך ילון ושלושים שנה למותו של דב סדן אנחנו מפרסמים שוב את מאמרה של ברכה דלמצקי־פישלר על הקשרים בין השלושה. The post "לַמְּדֵנִי דבר בדברי לשון" appeared first on האקדמיה ללשון העברית.
Thu Mar 05, 2020 14:35
Publication date: Available online 5 March 2020Source: Journal of VoiceAuthor(s): Craig H. Zalvan, Erick Yuen, Anila M. Thomas, Brian E. Benson
Thu Mar 05, 2020 15:28
Summary Purpose Galunisertib, a TGF-β inhibitor, has demonstrated antitumor effects in preclinical and radiographic responses in some patients with malignant glioma. This Phase 1b/2a trial investigated the clinical benefit of combining galunisertib with temozolomide-based radiochemotherapy (TMZ/RTX) in patients with newly diagnosed malignant glioma (NCT01220271). Methods This is an open-label, 2-arm Phase 1b/2a study (N = 56) of galunisertib (intermittent dosing: 14 days on/14...
Thu Mar 05, 2020 02:00
108 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 15:18
108 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 13:22
Publication date: Available online 4 March 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Caroline IE. Renner, Christiane Brendel, Horst Hummelsheim
Thu Mar 05, 2020 15:14
Publication date: Available online 4 March 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Tor Ivar Gjellesvik, Frank Becker, Arnt Erik Tjønna, Bent Indredavik, Halvard Nilsen, Berit Brurok, Tom Tørhaug, Maja Busuladzic, Stian Lydersen, Torunn Askim
Thu Mar 05, 2020 15:14
Publication date: Available online 4 March 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Daniel Wadsworth, Sally Lark
Thu Mar 05, 2020 15:14
Publication date: Available online 4 March 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): David N. Borg, Michele M. Foster, Melissa Legg, Rachel Jones, Elizabeth Kendall, Jennifer Fleming, Timothy Geraghty
Thu Mar 05, 2020 15:14
Journal of Cutaneous Medicine and Surgery, Ahead of Print. Crisaborole, a topical phosphodiesterase-4 inhibitor, was recently approved in 2016 for the treatment of mild to moderate atopic dermatitis in adults and children greater than 2 years of age. Since that time, several case reports and a small randomized controlled trial have been published regarding the off-label use of crisaborole for the treatment of other inflammatory dermatologic disorders. This paper reviews the current, albeit limited,...
Thu Mar 05, 2020 14:41
Abstract Androgenetic alopecia (AGA) and telogen effluvium (TE) are common causes of hair loss, with limited options for treatment. To determine the efficacy and safety of a new formulation kit (Pielus Anti‐hair loss® lotion and shampoo) containing anti‐inflammatory and antioxidant agents in patients with ET and/or AGA. This was a prospective, single‐arm, open‐label study with 35 women and 10 men, median age of 44 years, with clinical diagnosis of ET and/or AGA. They used the combination of shampoo...
Thu Mar 05, 2020 15:11
Publication date: Available online 4 March 2020Source: Journal of Surgical EducationAuthor(s): Carey Burton Wood, Kristen H. Yancey, Samuel N. Okerosi, Jaime Wiggleton, Nolan B. Seim, Kyle Mannion, James L. Netterville
Thu Mar 05, 2020 15:04
Publication date: Available online 4 March 2020Source: Journal of Surgical EducationAuthor(s): Terence Jackson, Edward E. Cho, Kei Nagatomo, Houssam G. Osman, Dhiresh Rohan Jeyarajah
Thu Mar 05, 2020 15:04
Abstract A hallmark of ductal carcinoma in situ (DCIS) progression is a loss of the surrounding ductal myoepithelium. However, whether compromise in myoepithelial differentiation, rather than overt cellular loss, can be used to predict the risk of DCIS progression is unknown. Here we address this question utilizing pure and mixed DCIS cases (N = 30) as surrogates for DCIS at low and high risk for progression, respectively. We used multiplex immunohistochemical staining to evaluate the relationship...
Thu Mar 05, 2020 15:00
Abstract Glioblastoma (GBM) is the most common and malignant brain tumor in adults. Recently, programmed death‐1/programmed death‐ligand 1 (PD‐1/PD‐L1) checkpoint blockades have been applied for GBM treatment. However, the mechanism of PD‐L1 upregulation in GBM is still unclear. COP9 signalosome 6 (CSN6) is crucial for maintaining the protein stabilization in cancer cells. In this study, we applied human GBM specimens and cell lines to investigate whether the EGFR‐ERK pathway regulates CSN6 for...
Thu Mar 05, 2020 15:00
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