Abstract Lung adenocarcinoma (LUAD), as a form of non‐small cell lung cancer (NSCLC), is the most frequently diagnosed lung cancer worldwide. To date, a few biomarkers have been reported to provide valuable information in guiding LUAD treatment. The aim of our study was to explore the functional role of pyrroline‐5‐carboxylate reductase 1 (PYCR1) in LUAD. Based on Oncomine database, we found that PYCR1 was highly expressed in LUAD tissues. We also confirmed an abnormal increase of PYCR1 expression...
Thu Mar 05, 2020 08:58
108 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 15:00
108 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 13:02
Publication date: Available online 4 March 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Hubert Szweda, Kinga Graczyk, Dawid Radomiak, Krzysztof Matuszewski, Bartosz Pawalowski
Thu Mar 05, 2020 14:57
Publication date: Available online 4 March 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Ramesh Arya, Harsh Goyal, Ayush Naik, Om Prakash Gurjar
Thu Mar 05, 2020 14:57
Publication date: Available online 4 March 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Carsten Nieder, Mandy Hintz, Ilinca Popp, Angelika Bilger, Anca L. Grosu
Thu Mar 05, 2020 14:57
Publication date: Available online 4 March 2020Source: Reports of Practical Oncology & RadiotherapyAuthor(s): Ganeshkumar Patel, Abhijit Mandal, Sunil Choudhary, Ritusha Mishra, Ravindra Shende
Thu Mar 05, 2020 14:57
Related Articles[Language competence of four-year-old children with immigration background in Hesse: quo vadis?] Laryngorhinootologie. 2020 Mar 04;: Authors: Zaretsky E, Lange BP, Hey C Abstract A sustainable integration of persons with immigration background is more topical than ever before. The importance of language as one of the key aspects of integration is beyond discussion. In 2018, ca. 1 091 000 persons with the non-German citizenship were registered...
Thu Mar 05, 2020 14:56
Related Articles[Evaluation of Universal Newborn Hearing Screening and follow-up]. Laryngorhinootologie. 2020 Mar 04;: Authors: Hall V, Brosch S, Hoffmann TK Abstract BACKGROUND: Universal newborn hearing screening (UNHS) was established in Germany in 2009. Even compliance was tested in early studies, there is little knowledge regarding the follow-up examination of children with suspected hearing disorder. METHODS: A retrospective evaluation...
Thu Mar 05, 2020 14:56
Related ArticlesSystematic metadata analysis of brown rot fungi gene expression data reveals the genes involved in Fenton's reaction and wood decay process. Mycology. 2020;11(1):22-37 Authors: Sista Kameshwar AK, Qin W Abstract Brown-rot fungi are rapid holocellulose degraders and are the most predominant degraders of coniferous wood products in North America. Brown-rot fungi degrades wood by both enzymatic (plant biomass degrading carbohydrate active...
Thu Mar 05, 2020 14:50
Related ArticlesNeutral ceramidase: Advances in mechanisms, cell regulation, and roles in cancer. Adv Biol Regul. 2019 01;71:141-146 Authors: Coant N, Hannun YA Abstract Extensive research conducted in the last three decades has identified the roles for the main bioactive sphingolipids, namely ceramide, sphingosine, and sphingosine 1-phosphate (S1P) as key regulators of cellular homeostasis, growth and death. One of the major groups of enzymes in the...
Thu Mar 05, 2020 14:50
2612 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/03/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Mar 05, 2020 14:49
Related ArticlesSubacute Thyroiditis: An Unusual Presentation of Fever of Unknown Origin Following Upper Respiratory Tract Infection. Am J Case Rep. 2020 Mar 04;21:e920515 Authors: Al-Tikrity MA, Magdi M, Abou Samra AB, Elzouki AY Abstract BACKGROUND Fever of unknown origin (FUO) is a diagnosis that requires a demanding workup from physicians before confirming a diagnosis. Thyroid diseases are a rare cause of FUO. Subacute thyroiditis is an inflammatory...
Thu Mar 05, 2020 14:47
Related ArticlesAngiogenesis and lead (Pb): is there a connection? Drug Chem Toxicol. 2020 Mar 04;:1-5 Authors: Machoń-Grecka A, Dobrakowski M, Kasperczyk A, Birkner E, Kasperczyk S Abstract Lead (Pb) is a toxic heavy metal ubiquitously distributed around the world, especially in industrial areas. Occupational and environmental exposures to Pb have detrimental effects on human health. Pb affects functioning of many systems of the human body, including...
Thu Mar 05, 2020 14:41
Related Articles[CME: Obstructive Sleep Apnea: A Common Disease]. Praxis (Bern 1994). 2020;109(3):207-213 Authors: Gaisl T, Thiel S, Kohler M Abstract CME: Obstructive Sleep Apnea: A Common Disease Abstract. Obstructive sleep apnea is a common sleep related breathing disorder with a collapse of the upper respiratory tract, leading to repetitive oxygen desaturations and 'micro arousals'. If the physiological sleep architecture is impaired, patients are...
Thu Mar 05, 2020 14:38
Related ArticlesSuccessful Management of Anti-TNF-Induced Psoriasis Despite Continuation of Therapy in a Pyoderma Gangrenosum Patient J Drugs Dermatol. 2020 Feb 01;19(2):199-201 Authors: Toussi A, Le ST, Barton VR, Ma C, Cheng MY, Sukhov A, Wilken R, Patel F, Wang E, Maverakis E Abstract Pyoderma gangrenosum is an inflammatory, neutrophil-mediated disorder that is difficult to treat. Tumor necrosis factor and other inflammatory mediators are among the...
Thu Mar 05, 2020 14:34
Related ArticlesUniversal Protocol in Mohs Micrographic Surgery: Incorporating a “Time Out” Procedure in Histopathologic Interpretation J Drugs Dermatol. 2020 Feb 01;19(2):198 Authors: Tang JC, Hanke CW Abstract In 1999, the Institute of Medicine’s (IOM) first report, “To Err Is Human”, brought forth the issue of medical error in patient care.1 In this publication, the IOM recognized that mistakes or failures to prevent mistakes were mostly caused by...
Thu Mar 05, 2020 14:34
Related ArticlesA Survey of Dermatologists’ Preparedness for Natural and Manmade Disasters J Drugs Dermatol. 2020 Feb 01;19(2):195-197 Authors: Murphy EC, Alptunaer T, Noll S, Phillips J, Friedman AJ Abstract Natural and manmade disasters cause a range of dermatologic manifestations, including secondary infections after a flood,1 irritation from blistering agents used in chemical warfare,2 or acute and chronic effects of cutaneous radiation syndrome.3...
Thu Mar 05, 2020 14:34
Related ArticlesManagement of Residual Psoriasis in Patients on Biologic Treatment J Drugs Dermatol. 2020 Feb 02;19(2):188-194 Authors: Haidari W, Pona A, Feldman SR Abstract While biologics are highly effective, most psoriasis patients do not achieve complete skin clearance with their biologic monotherapy. How to achieve complete skin clearance in psoriasis patients who fail their biologic is not well characterized. To describe treatment approaches...
Thu Mar 05, 2020 14:34
Related ArticlesMelasma’s Impact on Quality of Life J Drugs Dermatol. 2020 Feb 01;19(2):184-187 Authors: Kagha K, Fabi S, Goldman MP Abstract Melasma is a commonly acquired condition that mostly affects women with Fitzpatrick skin types III-VI with prominent brown pigmentation with or without an underlying erythema. Despite multiple treatment options, melasma can be challenging given its chronic and relapsing nature. The objective of this article is...
Thu Mar 05, 2020 14:34
Related ArticlesRandomized, Investigator-Blinded Study to Compare the Efficacy and Tolerance of a 650-microsecond, 1064-nm YAG Laser to a 308-nm Excimer Laser for the Treatment of Mild to Moderate Psoriasis Vulgaris J Drugs Dermatol. 2020 Feb 01;19(2):176-183 Authors: Nestor MS, Fischer D, Arnold D Abstract Background: Phototherapy is a safe and effective modality for the treatment of mild to moderate psoriasis. Objectives: To compare the efficacy and...
Thu Mar 05, 2020 14:34
Related ArticlesPneumatic Delivery of Hyaluronan for Skin Remodeling: A Comparative Review J Drugs Dermatol. 2020 Feb 01;19(2):170-175 Authors: Vinshtok Y, Cassuto D, Belenky I Abstract Jet Volumetric Remodeling (JVR) utilizes the principle of superficial soft tissue delivery of fluids, such as hyaluronic acid (HA) and other therapeutic materials. Dermal delivery of HA activates fibroblasts increasing collagen and elastin synthesis with a long-lasting...
Thu Mar 05, 2020 14:34
Related ArticlesLong-Term Efficacy and Safety of Superficial Radiation Therapy in Subjects With Nonmelanoma Skin Cancer: A Retrospective Registry Study J Drugs Dermatol. 2020 Feb 01;19(2):163-168 Authors: Roth W, Beer RE, Iyengar V, Bender T, Raymond I Abstract Background: Low-dose superficial radiation therapy (SRT) effectively treats nonmelanoma skin cancer (NMSC) without requiring invasive excision. SRT is especially safe and effective among the elderly...
Thu Mar 05, 2020 14:34
Related ArticlesIngenol Mebutate: Expanded Utility J Drugs Dermatol. 2020 Feb 1 j;19(2):156-161 Authors: Khalfe Y, Rosen T Abstract Ingenol mebutate (IM) is a novel drug that was developed for the treatment of actinic keratosis (AK). The drug works by a dual mechanism of action -- a rapid induction of cell death by necrosis along with a delayed neutrophil-mediated cellular cytotoxicity response.¹ Currently, IM is available as a 0.015% or 0.05% topical...
Thu Mar 05, 2020 14:34
Related ArticlesMultidisciplinary Real-World Experience With Bilastine, a Second Generation Antihistamine J Drugs Dermatol. 2020 Feb 01;19(2):145-154 Authors: Lynde CW, Sussman G, Dion PL, Guenther L, Hébert J, Rao J, Leek TV, Waserman S Abstract Introduction: Allergic conditions frequently require treatment with antihistamines. First-generation antihistamines can potentially interfere with restful sleep, cause “morning after” effects, impair learning...
Thu Mar 05, 2020 14:34
Related ArticlesClinical and Molecular Effects of Interleukin-17 Pathway Blockade in Psoriasis J Drugs Dermatol. 2020 Feb 01;19(2):138-143 Authors: Green L, Weinberg JM, Menter A, Soung J, Lain E, Jacobson A Abstract The interleukin-17 (IL-17) pathway plays a crucial role in the development of psoriasis. Briefly, naive T cells differentiate into helper T (Th17) cells through interaction with activated dendritic cells in the presence of IL-23, Th17 cells...
Thu Mar 05, 2020 14:34
Related ArticlesReal-World Clinical Experience With the IL-17 Receptor A Antagonist Brodalumab J Drugs Dermatol. 2020 Feb 01;19(2):132-136 Authors: Bettencourt MS Abstract Psoriasis is a chronic, inflammatory, remitting/relapsing autoimmune dermatologic condition that manifests with scaly, erythematous plaques. It has a significantly negative effect on patient quality of life, as well as increasing their risk of numerous comorbid diseases. Patients are...
Thu Mar 05, 2020 14:34
Related ArticlesIntralesional Triamcinolone Acetonide in the Treatment of Traction Alopecia J Drugs Dermatol. 2020 Feb 01;19(2):128-130 Authors: Uwakwe LN, De Souza B, Tovar-Garza A, McMichael AJ Abstract Traction alopecia (TA) is a form of hair loss caused by continuous and prolonged tension to the hair, most commonly seen in Black/African American women and children who wear hairstyles that pull excessively at the frontotemporal hairline. Dermatologists...
Thu Mar 05, 2020 14:34
Related ArticlesEffect of Calcipotriene/Betamethasone Dipropionate 0.005%/0.064% Foam on Target Lesions in Plaque Psoriasis: A Post-Hoc Analysis J Drugs Dermatol. 2020 Feb 01;19(2):121-126 Authors: Veverka KA, Patel DS, Anger T, Hansen B, Del Rosso J, Kircik LH Abstract Objective: Investigate the effect of fixed-combination calcipotriene 0.005% plus betamethasone dipropionate 0.064% (Cal/BD) foam on target lesion severity in plaque psoriasis. Design:...
Thu Mar 05, 2020 14:34
Related ArticlesMiddle ear Pathologies in Adults Living with Human Immunodeficiency Virus: A Systematic Review. Ann Otol Rhinol Laryngol. 2020 Mar 03;:3489420909847 Authors: Sebothoma B, Khoza-Shangase K Abstract INTRODUCTION: Middle ear pathologies have been linked with HIV. The onset and development of these pathologies in individuals with HIV have not been categorized; and clarity has not been gained regarding whether their presentation is any...
Thu Mar 05, 2020 14:31
Related ArticlesDecreased Tongue Volume Post Radiation. Ann Otol Rhinol Laryngol. 2020 Mar 04;:3489420911668 Authors: Garber D, Rotsides J, Abu-Ghanem S, Bandler I, Smith A, Oyfe I, Swahn DM, Hagiwara M, Amin M, Johnson AM Abstract OBJECTIVES: To evaluate volume changes within the tongue post chemoradiation therapy (CRT). STUDY DESIGN: Retrospective review. SETTING: Academic Medical Center. SUBJECTS AND METHODS: Subjects...
Thu Mar 05, 2020 14:31
Related ArticlesDecision Quality Among Parents Who Are Offered Ventilation Tube Insertion for Their Children. Ann Otol Rhinol Laryngol. 2020 Mar 04;:3489420909850 Authors: Newby MD, Zalzal HG, Ramadan J, Kellermeyer BM, Carr MM Abstract OBJECTIVE: To develop a Decision Quality (DQ) tool to measure parents' DQ concerning ventilation tube (VT) insertion in their children. METHOD: Parental survey during 2017 to 2018 in a tertiary care pediatric...
Thu Mar 05, 2020 14:31
Publication date: Available online 4 March 2020Source: Medical HypothesesAuthor(s): Sukru Demir, Sefa Key, Turker Tuncer, Sengul Dogan
Thu Mar 05, 2020 14:30
Publication date: Available online 4 March 2020Source: Medical HypothesesAuthor(s): Valentina Colonnello, Alessandro Agostini
Thu Mar 05, 2020 14:30
Publication date: Available online 4 March 2020Source: Medical HypothesesAuthor(s): Marina Ziliotto, Raul Marques Rodrigues, José Artur Bogo Chies
Thu Mar 05, 2020 14:30
Publication date: Available online 5 March 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Hanwen Chu, Feifei Xu, Xin Xu
Thu Mar 05, 2020 14:28
Related ArticlesA new office-based procedure for treatment of snoring: The S.I.Le.N.C.E. study. Laryngoscope Investig Otolaryngol. 2020 Feb;5(1):24-30 Authors: Friedman M, Gillespie MB, Shabdiz FA, Hiltzik DH, Meyer TA, Ahn J, Catalano PJ, Joseph NJ Abstract Objective: Demonstrate the safety and effectiveness of palatal foreshortening and stiffening in reducing snoring severity in nonobstructive sleep apnea (non-OSA) patients complaining of chronic disruptive...
Thu Mar 05, 2020 14:27
Related ArticlesDetermination of high-risk HPV status of head and neck squamous cell carcinoma using the Roche cobas HPV test on cytologic specimens and acellular supernatant fluid. Cancer Cytopathol. 2020 Mar 04;: Authors: Wright MF, Weiss VL, Lewis JS, Schmitz JE, Ely KA Abstract BACKGROUND: High-risk human papillomavirus-positive (hrHPV+) oropharyngeal squamous cell carcinomas comprise a subset of head and neck squamous cell carcinomas (HNSCCs) with...
Thu Mar 05, 2020 16:20
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