Molecules, Vol. 25, Pages 1164: Beneficial Regulation of Cellular Oxidative Stress Effects, and Expression of Inflammatory, Angiogenic, and the Extracellular Matrix Remodeling Proteins by 1α,25-Dihydroxyvitamin D3 in a Melanoma Cell Line Molecules doi: 10.3390/molecules25051164 Authors: Neena Philips Philips Samuel Thomas Keller Asma Alharbi Samar Alshalan Sara-Ali Shamlan The causes of cancer include the cellular accumulation reactive oxygen species (ROS), which overrides...
Thu Mar 05, 2020 02:00
Molecules, Vol. 25, Pages 1165: Interaction of Coumarin Phytoestrogens with ERα and ERβ: A Molecular Dynamics Simulation Study Molecules doi: 10.3390/molecules25051165 Authors: Ting Wang Yunfei Wang Xuming Zhuang Feng Luan Chunyan Zhao M. Natália D. S. Cordeiro Coumarin phytoestrogens, as one of the important classes of phytoestrogens, have been proved to play an important role in various fields of human life. In this study, molecular simulation method including molecular...
Thu Mar 05, 2020 02:00
Molecules, Vol. 25, Pages 1162: Design, Synthesis, and Biological Evaluation of Aromatic Amide-Substituted Benzimidazole-Derived Chalcones. The Effect of Upregulating TP53 Protein Expression Molecules doi: 10.3390/molecules25051162 Authors: Lintao Wu Yuting Yang Zhijun Wang Xi Wu Feng Su Mengyao Li Xiaobi Jing Chun Han A series of benzimidazole-derived chalcones containing aromatic amide substituent were designed and synthesized. All of the chalcone compounds were...
Thu Mar 05, 2020 02:00
Molecules, Vol. 25, Pages 1163: Characterizations and Assays of α-Glucosidase Inhibition Activity on Gallic Acid Cocrystals: Can the Cocrystals be Defined as a New Chemical Entity During Binding with the α-Glucosidase? Molecules doi: 10.3390/molecules25051163 Authors: Na Xue Yutao Jia Congwei Li Binnan He Caiqin Yang Jing Wang Cocrystallization with co-former (CCF) has proved to be a powerful approach to improve the solubility and even bioavailability of poorly water-soluble...
Thu Mar 05, 2020 02:00
Molecules, Vol. 25, Pages 1161: Recent Advances in Encapsulation, Protection, and Oral Delivery of Bioactive Proteins and Peptides using Colloidal Systems Molecules doi: 10.3390/molecules25051161 Authors: Sarah L. Perry David Julian McClements There are many areas in medicine and industry where it would be advantageous to orally deliver bioactive proteins and peptides (BPPs), including ACE inhibitors, antimicrobials, antioxidants, hormones, enzymes, and vaccines. A major challenge...
Thu Mar 05, 2020 02:00
Molecules, Vol. 25, Pages 1157: Characterization of the Lipid Oxidation Process of Robusta Green Coffee Beans and Shelf Life Prediction during Accelerated Storage Molecules doi: 10.3390/molecules25051157 Authors: Sha Cong Wenjiang Dong Jianping Zhao Rongsuo Hu Yuzhou Long Xiaoxing Chi The lipid oxidation process of Robusta green coffee beans was characterized during accelerated storage for 20 days at 40 °C, 50 °C, and 60 °C. The conventional oxidation...
Thu Mar 05, 2020 02:00
Molecules, Vol. 25, Pages 1159: In Vivo Positive Magnetic Resonance Imaging Applications of Poly(methyl vinyl ether-alt-maleic acid)-coated Ultra-small Paramagnetic Gadolinium Oxide Nanoparticles Molecules doi: 10.3390/molecules25051159 Authors: Mohammad Yaseen Ahmad Md. Wasi Ahmad Huan Yue Son Long Ho Ji Ae Park Ki-Hye Jung Hyunsil Cha Shanti Marasini Adibehalsadat Ghazanfari Shuwen Liu Tirusew Tegafaw Kwon-Seok Chae Yongmin Chang Gang Ho Lee The...
Thu Mar 05, 2020 02:00
Molecules, Vol. 25, Pages 1158: Fully Biobased Epoxy Resins from Fatty Acids and Lignin Molecules doi: 10.3390/molecules25051158 Authors: Pablo Ortiz Richard Vendamme Walter Eevers The use of renewable resources for plastic production is an imperious need for the reduction of the carbon footprint and the transition towards a circular economy. With that goal in mind, fully biobased epoxy resins have been designed and prepared by combining epoxidized linseed oil, lignin, and a biobased...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 473: ZnO Nanostructures with Antibacterial Properties Prepared by a Green Electrochemical-Thermal Approach Nanomaterials doi: 10.3390/nano10030473 Authors: Maria Chiara Sportelli Rosaria Anna Picca Margherita Izzi Gerardo Palazzo Roberto Gristina Massimo Innocenti Luisa Torsi Nicola Cioffi Zinc oxide (ZnO) nanostructures are widely applied materials, and are also capable of antimicrobial action. They can be obtained by several methods,...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 472: Vertically Aligned Single-Crystalline CoFe2O4 Nanobrush Architectures with High Magnetization and Tailored Magnetic Anisotropy Nanomaterials doi: 10.3390/nano10030472 Authors: Fan Gao Farmer Lee Guo Mu Wang Fitzsimmons Chisholm Ward Eres Lee Micrometer-tall vertically aligned single-crystalline CoFe2O4 nanobrush architectures with extraordinarily large aspect ratio have been achieved by the precise control...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 471: AACVD Synthesis and Characterization of Iron and Copper Oxides Modified ZnO Structured Films Nanomaterials doi: 10.3390/nano10030471 Authors: Claros Setka Jimenez Vallejos Non-modified (ZnO) and modified (Fe2O3@ZnO and CuO@ZnO) structured films are deposited via aerosol assisted chemical vapor deposition. The surface modification of ZnO with iron or copper oxides is achieved in a second aerosol assisted chemical vapor deposition step and...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 474: Fly Ash, from Recycling to Potential Raw Material for Mesoporous Silica Synthesis Nanomaterials doi: 10.3390/nano10030474 Authors: Marius Gheorghe Miricioiu Violeta-Carolina Niculescu In order to meet the increasing energy demand and to decrease the dependency on coal, environmentally friendly methods for fly ash utilization are required. In this respect, the priority is to identify the fly ash properties and to consider its potential as raw material...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 469: A Universal Method to Weld Individual One-Dimensional Nanostructures with a Tungsten Needle Based on Synergy of the Electron Beam and Electrical Current Nanomaterials doi: 10.3390/nano10030469 Authors: Peng Zhao Yu Zhang Shuai Tang Runze Zhan Juncong She Jun Chen Shaozhi Deng One-dimensional (1D) nanostructures are extensively used in the design of novel electronic devices, sensors, and energy devices. One of the major challenges faced...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 470: Paper Functionalized with Nanostructured TiO2/AgBr: Photocatalytic Degradation of 2–Propanol under Solar Light Irradiation and Antibacterial Activity Nanomaterials doi: 10.3390/nano10030470 Authors: Mouheb Sboui Soraa Bouattour Michelangelo Gruttadauria Giuseppe Marcì Leonarda Francesca Liotta Sami Boufi A facile method to produce paper–TiO2 decorated with AgBr nanoparticles by a mild hydrothermal process at 140 °C was...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 468: Thin Films Based on Cobalt Phthalocyanine:C60 Fullerene:ZnO Hybrid Nanocomposite Obtained by Laser Evaporation Nanomaterials doi: 10.3390/nano10030468 Authors: Marcela Socol Nicoleta Preda Andreea Costas Bogdana Borca Gianina Popescu-Pelin Andreea Mihailescu Gabriel Socol Anca Stanculescu Matrix-assisted pulsed laser evaporation (MAPLE) was used to deposit hybrid nanocomposite thin films based on cobalt phthalocyanine (CoPc), C60...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 467: Core–Shell Structured Phenolic Polymer@TiO2 Nanosphere with Enhanced Visible-Light Photocatalytic Efficiency Nanomaterials doi: 10.3390/nano10030467 Authors: Xiankui Xu Lei Zhang Shihua Zhang Yanpeng Wang Baoying Liu Yanrong Ren Core–shell structured TiO2 is a promising solution to promote the photocatalytic effectiveness in visible light. Compared to metal or semiconductor materials, polymers are rarely used as the core materials...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 465: Effects of Titanium Dioxide Nanoparticles on the Hprt Gene Mutations in V79 Hamster Cells Nanomaterials doi: 10.3390/nano10030465 Authors: Alena Kazimirova Naouale El Yamani Laura Rubio Alba García-Rodríguez Magdalena Barancokova Ricard Marcos Maria Dusinska The genotoxicity of anatase/rutile TiO2 nanoparticles (TiO2 NPs, NM105 at 3, 15 and 75 µg/cm2) was assessed with the mammalian in-vitro Hypoxanthine guanine phosphoribosyl...
Thu Mar 05, 2020 02:00
Nanomaterials, Vol. 10, Pages 466: Green and Sustainable Manufacture of Ultrapure Engineered Nanomaterials Nanomaterials doi: 10.3390/nano10030466 Authors: David Ortiz de Zárate Carlos García-Meca Elena Pinilla-Cienfuegos José A. Ayúcar Amadeu Griol Laurent Bellières Esther Hontañón Frank E. Kruis Javier Martí Nanomaterials with very specific features (purity, colloidal stability, composition, size, shape, location…) are commonly requested by cutting-edge...
Thu Mar 05, 2020 02:00
Nutrients, Vol. 12, Pages 701: Dietary and Serum Omega-6/Omega-3 Fatty Acids Are Associated with Physical and Metabolic Function in Stroke Survivors Nutrients doi: 10.3390/nu12030701 Authors: Monica C. Serra Alice S. Ryan Charlene E. Hafer-Macko Manuel Yepes Fadi B. Nahab Thomas R. Ziegler The purpose of this study was to quantify habitual dietary and systemic omega-6 and omega-3 fatty acids and their ratios and to determine their relationship with physical and metabolic...
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Nutrients, Vol. 12, Pages 698: Cocoa, Chocolate, and Human Health Nutrients doi: 10.3390/nu12030698 Authors: Zimmermann Ellinger Cocoa has been used as a ceremonial and hedonistic food for thousands of years in the tropical parts of America and for hundreds of years in the western world. […]
Thu Mar 05, 2020 02:00
Nutrients, Vol. 12, Pages 699: Adipokines and Endotoxemia Correlate with Hepatic Steatosis in Non-Alcoholic Fatty Liver Disease (NAFLD) Nutrients doi: 10.3390/nu12030699 Authors: Nier Huber Labenz Michel Bergheim Schattenberg (1) Background: The etiology of non-alcoholic fatty liver disease (NAFLD) is multifactorial. Dietary composition has been implicated as a factor modulating intestinal barrier and could affect disease severity. The aim of this study was to evaluate...
Thu Mar 05, 2020 02:00
Nutrients, Vol. 12, Pages 700: Physalis peruviana L. Pulp Prevents Liver Inflammation and Insulin Resistance in Skeletal Muscles of Diet-Induced Obese Mice Nutrients doi: 10.3390/nu12030700 Authors: Francisco Pino-de la Fuente Diego Nocetti Camila Sacristán Paulina Ruiz Julia Guerrero Gonzalo Jorquera Ernesto Uribe José Luis Bucarey Alejandra Espinosa Luis Puente A chronic high-fat diet (HFD) produces obesity, leading to pathological consequences in the liver...
Thu Mar 05, 2020 02:00
Nutrients, Vol. 12, Pages 697: Self-Reported Omega-3 Supplement Use Moderates the Association between Age and Exercising Cerebral Blood Flow Velocity in Older Adults Nutrients doi: 10.3390/nu12030697 Authors: Carolyn S. Kaufman Eric D. Vidoni Jeffrey M. Burns Mohammed R. Alwatban Sandra A. Billinger Cerebral blood flow (CBF) decreases across the lifespan, and chronic conditions such as dementia and stroke accelerate this decline. Impaired CBF results in reduced delivery of...
Thu Mar 05, 2020 02:00
Nutrients, Vol. 12, Pages 696: Comment on: “A Systematic Review of Organic Versus Conventional Food Consumption: Is There a Measurable Benefit on Human Health? Nutrients 2020, 12, 7” Nutrients doi: 10.3390/nu12030696 Authors: Laura Di Renzo Antonino De Lorenzo Giuseppe Merra Paola Gualtieri Dear Editor [...]
Thu Mar 05, 2020 02:00
Nutrients, Vol. 12, Pages 694: Association between Soft Drink Consumption and Aggressive Behaviour among a Quarter Million Adolescents from 64 Countries Based on the Global School-Based Student Health Survey (GSHS) Nutrients doi: 10.3390/nu12030694 Authors: Zumin Shi Ahmed Malki Abdel-Salam G Abdel-Salam Jianghong Liu Hatem Zayed Soft drink consumption has become a significant public health concern that is associated with various adverse health outcomes. We aim to examine...
Thu Mar 05, 2020 02:00
Particles, Vol. 3, Pages 193-207: D Polarization as an Additional Constraint on New Physics in the b→cτν¯τ Transition* Particles doi: 10.3390/particles3010016 Authors: Mikhail A. Ivanov Jürgen G. Körner Pietro Santorelli Chien-Thang Tran Measurements of the branching fractions of the semileptonic decays B → D ( * ) τ ν ¯ τ and B c → J / ψ τ ν ¯ τ systematically...
Thu Mar 05, 2020 02:00
Pathogens, Vol. 9, Pages 191: Urinary N-acetyltyramine-O,β-glucuronide in Persons with Onchocerciasis-Associated Epilepsy Pathogens doi: 10.3390/pathogens9030191 Authors: Hotterbeekx Dusabimana Mandro Abhafule Deogratias Siewe Fodjo Abrams Colebunders We investigated urinary N-acetyltyramine-O,β-glucuronide (NATOG) levels as a biomarker for active Onchocerca volvulus infection in an onchocerciasis-endemic area in the Democratic Republic of Congo...
Thu Mar 05, 2020 02:00
Pathogens, Vol. 9, Pages 193: Cerebral HSV-1 Vasculitis as a Fatal Complication of Immunosuppression in Non-Hodgkin´s Lymphoma: A Case Report and Review of the Literature Pathogens doi: 10.3390/pathogens9030193 Authors: Nardone Carnicelli Brigo Pikija Hauer Sellner Patients with lymphoma are predisposed to infection because of the immunocompromised state related to the disease itself and as a consequence of chemo-/radiotherapy. Here, we report a case of Herpes-simplex...
Thu Mar 05, 2020 02:00
Pathogens, Vol. 9, Pages 192: Chemical Composition, Antimicrobial activity, in Vitro Cytotoxicity and Leukotoxin Neutralization of Essential Oil from Origanum vulgare against Aggregatibacter actinomycetemcomitans Pathogens doi: 10.3390/pathogens9030192 Authors: Akkaoui Johansson Yagoubi Haubek El hamidi Rida Claesson Ennibi In this study, the essential oil of Origanum vulgare was evaluated for putative antibacterial activity against six clinical strains and...
Thu Mar 05, 2020 02:00
Pathogens, Vol. 9, Pages 194: Evaluation of Quality Control Methods for Foot-And-Mouth Disease Vaccines by High-Performance Liquid Chromatography Pathogens doi: 10.3390/pathogens9030194 Authors: Kim Yun Kim Lee Kim Kim Kang Kim Seo Foot-and-mouth disease (FMD) is considered one of the highly contagious viral infections affecting livestock. In Korea, an FMD vaccination policy has been implemented nationwide since 2010 for the prevention and control of...
Thu Mar 05, 2020 02:00
Pathogens, Vol. 9, Pages 190: Atypical Presentation of Methicillin-Susceptible Staphylococcus aureus Infection in a Dengue-Positive Patient: A Case Report with Virulence Genes Analysis Pathogens doi: 10.3390/pathogens9030190 Authors: Soo Tein Ngoi Yee Wan Lee Wen Kiong Niek Foong Kee Kan Sazaly AbuBakar Sasheela Sri La Sri Ponnampalavanar Nuryana Idris Cindy Shuan Ju Teh Concurrent bacteraemia in patients with dengue fever is rarely reported. We report a case of...
Thu Mar 05, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 41: Opipramol Inhibits Lipolysis in Human Adipocytes without Altering Glucose Uptake and Differently from Antipsychotic and Antidepressant Drugs with Adverse Effects on Body Weight Control Pharmaceuticals doi: 10.3390/ph13030041 Authors: Carpéné Les Mercader Gomez-Zorita Grolleau Boulet Fontaine Iglesias-Osma Garcia-Barrado Treatment with several antipsychotic drugs exhibits a tendency to induce weight gain and diabetic...
Thu Mar 05, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 39: (Radio)Theranostic Patient Management in Oncology Exemplified by Neuroendocrine Neoplasms, Prostate Cancer, and Breast Cancer Pharmaceuticals doi: 10.3390/ph13030039 Authors: Velikyan The role of nuclear medicine in the management of oncological patients has expanded during last two decades. The number of radiopharmaceuticals contributing to the realization of theranostics/radiotheranostics in the context of personalized medicine is increasing. This...
Thu Mar 05, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 40: 2019 FDA TIDES (Peptides and Oligonucleotides) Harvest Pharmaceuticals doi: 10.3390/ph13030040 Authors: Al Shaer Al Musaimi Albericio de la Torre 2019 has been an excellent year in terms of peptides and oligonucleotides (TIDES) approved by the FDA. Despite the drop in the number of total drugs approved by the FDA in 2019 in comparison with 2018 (48 vs. 59), the total number of TIDES authorized increased (seven vs. three). Year after year,...
Thu Mar 05, 2020 02:00
Pharmaceutics, Vol. 12, Pages 235: Design Space Identification and Visualization for Continuous Pharmaceutical Manufacturing Pharmaceutics doi: 10.3390/pharmaceutics12030235 Authors: Samir Diab Dimitrios I. Gerogiorgis Progress in continuous flow chemistry over the past two decades has facilitated significant developments in the flow synthesis of a wide variety of Active Pharmaceutical Ingredients (APIs), the foundation of Continuous Pharmaceutical Manufacturing (CPM), which has gained...
Thu Mar 05, 2020 02:00
Pharmaceutics, Vol. 12, Pages 231: Optimization of Drug Permeation from 8% Ciclopirox Cyclodextrin/Poloxamer-Soluble Polypseudorotaxane-Based Nail Lacquers Pharmaceutics doi: 10.3390/pharmaceutics12030231 Authors: Cutrín-Gómez Conde-Penedo Anguiano-Igea Gómez-Amoza Otero-Espinar Cyclodextrin/poloxamer-soluble polypseudorotaxane-based nail lacquers have demonstrated significant capacity for promoting the permeation of drugs into the nail plate. Furthermore, previous studies...
Thu Mar 05, 2020 02:00
Pharmaceutics, Vol. 12, Pages 233: Gene Therapy in Cancer Treatment: Why Go Nano? Pharmaceutics doi: 10.3390/pharmaceutics12030233 Authors: Roma-Rodrigues Rivas-García Baptista Fernandes The proposal of gene therapy to tackle cancer development has been instrumental for the development of novel approaches and strategies to fight this disease, but the efficacy of the proposed strategies has still fallen short of delivering the full potential of gene therapy in the clinic....
Thu Mar 05, 2020 02:00
Pharmaceutics, Vol. 12, Pages 230: In Silico Optimization of Fiber-Shaped Aerosols in Inhalation Therapy for Augmented Targeting and Deposition across the Respiratory Tract Pharmaceutics doi: 10.3390/pharmaceutics12030230 Authors: Shachar-Berman Bhardwaj Ostrovski Das Koullapis Kassinos Sznitman Motivated by a desire to uncover new opportunities for designing the size and shape of fiber-shaped aerosols towards improved pulmonary drug delivery deposition outcomes,...
Thu Mar 05, 2020 02:00
Pharmaceutics, Vol. 12, Pages 234: Improved Stability of Rifampicin in the Presence of Gastric-Resistant Isoniazid Microspheres in Acidic Media Pharmaceutics doi: 10.3390/pharmaceutics12030234 Authors: Mwila Walker The degradation of rifampicin (RIF) in an acidic medium to form 3-formyl rifamycin SV, a poorly absorbed compound, is accelerated in the presence of isoniazid, contributing to the poor bioavailability of rifampicin. This manuscript presents a novel approach in which isoniazid...
Thu Mar 05, 2020 02:00
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