Δευτέρα 16 Μαρτίου 2020


JCM, Vol. 9, Pages 801: Radiographic Sagittal Tibio-Talar Offset in Ankle Arthrodesis—Accuracy and Reliability of Measurements
JCM, Vol. 9, Pages 801: Radiographic Sagittal Tibio-Talar Offset in Ankle Arthrodesis—Accuracy and Reliability of Measurements Journal of Clinical Medicine doi: 10.3390/jcm9030801 Authors: Sophie Schieder Elena Nemecek Reinhard Schuh Alexander Kolb Reinhard Windhager Madeleine Willegger Radiographic outcome assessment of ankle arthrodesis (AA) requires accurate measurement techniques. This study aimed to identify the most reliable methods for sagittal tibio-talar alignment...
Journal of Clinical Medicine
Mon Mar 16, 2020 02:00
JoF, Vol. 6, Pages 37: Genome Sequence Analysis of Auricularia heimuer Combined with Genetic Linkage Map
JoF, Vol. 6, Pages 37: Genome Sequence Analysis of Auricularia heimuer Combined with Genetic Linkage Map Journal of Fungi doi: 10.3390/jof6010037 Authors: Ming Fang Xiaoe Wang Ying Chen Peng Wang Lixin Lu Jia Lu Fangjie Yao Youmin Zhang Auricularia heimuer is one of the most popular edible fungi in China. In this study, the whole genome of A. heimuer was sequenced on the Illumina HiSeq X system and compared with other mushrooms genomes. As a wood-rotting fungus,...
Journal of Fungi
Mon Mar 16, 2020 02:00
Medicina, Vol. 56, Pages 131: Yarsagumba is a Promising Therapeutic Option for Treatment of Pulmonary Hypertension due to the Potent Anti-Proliferative and Vasorelaxant Properties
Medicina, Vol. 56, Pages 131: Yarsagumba is a Promising Therapeutic Option for Treatment of Pulmonary Hypertension due to the Potent Anti-Proliferative and Vasorelaxant Properties Medicina doi: 10.3390/medicina56030131 Authors: Himal Luitel Tatyana Novoyatleva Akylbek Sydykov Aleksandar Petrovic Argen Mamazhakypov Bhuminand Devkota Malgorzata Wygrecka Hossein Ardeschir Ghofrani Sergey Avdeev Ralph Theo Schermuly Djuro Kosanovic Background and objectives:...
Medicina
Mon Mar 16, 2020 02:00
Medicina, Vol. 56, Pages 130: Impact of Elderly Masticatory Performance on Nutritional Status: An Observational Study
Medicina, Vol. 56, Pages 130: Impact of Elderly Masticatory Performance on Nutritional Status: An Observational Study Medicina doi: 10.3390/medicina56030130 Authors: Luca Aquilanti Sonila Alia Sofia Pugnaloni Erminia Coccia Marco Mascitti Andrea Santarelli Luisa Limongelli Gianfranco Favia Margherita Mancini Arianna Vignini Giorgio Rappelli Background and Objectives: Masticatory limitations on the dietary habits of edentulous subjects restrict their access...
Medicina
Mon Mar 16, 2020 02:00
Metabolites, Vol. 10, Pages 111: Compound Characterization and Metabolic Profile Elucidation after In Vitro Gastrointestinal and Hepatic Biotransformation of an Herniaria hirsuta Extract Using Unbiased Dynamic Metabolomic Data Analysis
Metabolites, Vol. 10, Pages 111: Compound Characterization and Metabolic Profile Elucidation after In Vitro Gastrointestinal and Hepatic Biotransformation of an Herniaria hirsuta Extract Using Unbiased Dynamic Metabolomic Data Analysis Metabolites doi: 10.3390/metabo10030111 Authors: Laura Peeters Anastasia Van der Auwera Charlie Beirnaert Sebastiaan Bijttebier Kris Laukens Luc Pieters Nina Hermans Kenn Foubert Herniaria hirsuta L. (Caryophyllaceae) is used for treatment...
Metabolites
Mon Mar 16, 2020 02:00
Microorganisms, Vol. 8, Pages 418: Comparison of LAL and rFC Assays—Participation in a Proficiency Test Program between 2014 and 2019
Microorganisms, Vol. 8, Pages 418: Comparison of LAL and rFC Assays—Participation in a Proficiency Test Program between 2014 and 2019 Microorganisms doi: 10.3390/microorganisms8030418 Authors: Piehler Roeder Blessing Reich Endotoxin (lipopolysaccharide) testing of drugs is routinely required in pharmaceutical industries. Suitable compendial assays are defined by national pharmacopoeias. At this time, Limulus Amoebocyte Lysate (LAL) assays are the gold standard. LAL is used...
Microorganisms
Mon Mar 16, 2020 02:00
Microorganisms, Vol. 8, Pages 419: Epstein–Barr Virus Infection of Oral Squamous Cells
Microorganisms, Vol. 8, Pages 419: Epstein–Barr Virus Infection of Oral Squamous Cells Microorganisms doi: 10.3390/microorganisms8030419 Authors: Heawchaiyaphum Iizasa Ekalaksananan Burassakarn Kiyono Kanehiro Yoshiyama Pientong The Epstein–Barr virus (EBV) is a human herpesvirus associated with various cancers. The number of reports that describe infection of EBV in oral squamous carcinoma cells is increasing. However, there is no available in...
Microorganisms
Mon Mar 16, 2020 02:00
Microorganisms, Vol. 8, Pages 417: A Review and Perspective of eDNA Application to Eutrophication and HAB Control in Freshwater and Marine Ecosystems
Microorganisms, Vol. 8, Pages 417: A Review and Perspective of eDNA Application to Eutrophication and HAB Control in Freshwater and Marine Ecosystems Microorganisms doi: 10.3390/microorganisms8030417 Authors: Qi Liu Yun Zhang Han Wu Fengwen Liu Wei Peng Xiaonan Zhang Fengqin Chang Ping Xie Hucai Zhang Changing ecological communities in response to anthropogenic activities and climate change has become a worldwide problem. The eutrophication of waterbodies in freshwater...
Microorganisms
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1354: Electrical and Optical Properties of Silicon Oxide Lignin Polylactide (SiO2-L-PLA)
Molecules, Vol. 25, Pages 1354: Electrical and Optical Properties of Silicon Oxide Lignin Polylactide (SiO2-L-PLA) Molecules doi: 10.3390/molecules25061354 Authors: Fal Bulanda Traciak Sobczak Kuzioła Grąz Budzik Oleksy Żyła This paper presents a study on the electrical properties of new polylactide-basednanocomposites with the addition of silicon-dioxide–lignin nanoparticles and glycerine as a plasticizer.Four samples were prepared with nanoparticle...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1353: From Discrete Complexes to Metal–Organic Layered Materials: Remarkable Hydrogen Bonding Frameworks
Molecules, Vol. 25, Pages 1353: From Discrete Complexes to Metal–Organic Layered Materials: Remarkable Hydrogen Bonding Frameworks Molecules doi: 10.3390/molecules25061353 Authors: Queirós Silva de Castro Cunha-Silva A series of metal–organic coordination complexes based on alkaline-earth metal centers [Mg(II), Ca(II), and Ba(II)] and the ligand 5-aminoisophthalate (aip2−) revealed notable structural diversity, both in the materials’ dimensionality...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1351: Immunomodulatory Effects of Lycium barbarum Polysaccharide Extract and Its Uptake Behaviors at the Cellular Level
Molecules, Vol. 25, Pages 1351: Immunomodulatory Effects of Lycium barbarum Polysaccharide Extract and Its Uptake Behaviors at the Cellular Level Molecules doi: 10.3390/molecules25061351 Authors: Feng Xiao Liu Wang Zhang Bing Liu Zhang Shangguan Lycium barbarum L. is a widely used functional food and medicinal herb in Asian countries. L. barbarium polysaccharides (LBP) are considered as one of the major medicinal components of L. barbarium fruit and exhibits...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1352: Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori
Molecules, Vol. 25, Pages 1352: Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori Molecules doi: 10.3390/molecules25061352 Authors: Fan Guo Zeng Wei You Wang Pang Song Taking palmatine (PMT) as the lead, 20 new PMT derivatives were synthesized and examined for their antibacterial activities against six tested metronidazole (MTZ)-resistant Helicobacter pylori (H. pylori)...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1348: Multiple Applications of a Novel Cationic Gemini Surfactant: Anti-Microbial, Anti-Biofilm, Biocide, Salinity Corrosion Inhibitor, and Biofilm Dispersion (Part II)
Molecules, Vol. 25, Pages 1348: Multiple Applications of a Novel Cationic Gemini Surfactant: Anti-Microbial, Anti-Biofilm, Biocide, Salinity Corrosion Inhibitor, and Biofilm Dispersion (Part II) Molecules doi: 10.3390/molecules25061348 Authors: A. Labena M. A. Hegazy Radwa M. Sami Wael N. Hozzein The Egyptian petroleum industries are incurring severe problems with corrosion, particularly corrosion that is induced by sulfidogenic microbial activities in harsh salinity environments...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1349: On the Use of Iron in Organic Chemistry
Molecules, Vol. 25, Pages 1349: On the Use of Iron in Organic Chemistry Molecules doi: 10.3390/molecules25061349 Authors: Arnar Guðmundsson Jan-E. Bäckvall Transition metal catalysis in modern organic synthesis has largely focused on noble transition metals like palladium, platinum and ruthenium. The toxicity and low abundance of these metals, however, has led to a rising focus on the development of the more sustainable base metals like iron, copper and nickel for use in catalysis....
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1345: The Evolution of Pleconaril: Modified O-Alkyl Linker Analogs Have Biological Activity towards Coxsackievirus B3 Nancy
Molecules, Vol. 25, Pages 1345: The Evolution of Pleconaril: Modified O-Alkyl Linker Analogs Have Biological Activity towards Coxsackievirus B3 Nancy Molecules doi: 10.3390/molecules25061345 Authors: Alexandrina Volobueva Anna Egorova Anastasia Galochkina Sean Ekins Vladimir Zarubaev Vadim Makarov Coxsackieviruses type B are one of the most common causes of mild upper respiratory and gastrointestinal illnesses. At the time of writing, there are no approved drugs for effective...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1350: The Use of Fluorescence Spectrometry to Determine the Botanical Origin of Filtered Honeys
Molecules, Vol. 25, Pages 1350: The Use of Fluorescence Spectrometry to Determine the Botanical Origin of Filtered Honeys Molecules doi: 10.3390/molecules25061350 Authors: Aleksandra Wilczyńska Natalia Żak The aim of this study was to determine whether fluorescence spectrometry can be used to identify the botanical origin of filtered honeys. Sixty-two honey samples with different botanical origins, both filtered and unfiltered, were investigated in order to examine their fluorescence...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1347: Quinolone Complexes with Lanthanide Ions: An Insight into their Analytical Applications and Biological Activity
Molecules, Vol. 25, Pages 1347: Quinolone Complexes with Lanthanide Ions: An Insight into their Analytical Applications and Biological Activity Molecules doi: 10.3390/molecules25061347 Authors: Ana-Mădălina Măciucă Alexandra-Cristina Munteanu Valentina Uivarosi Quinolones comprise a series of synthetic bactericidal agents with a broad spectrum of activity and good bioavailability. An important feature of these molecules is their capacity to bind metal ions in complexes with relevant...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1346: Effects of Exogenous Abscisic Acid on Bioactive Components and Antioxidant Capacity of Postharvest Tomato during Ripening
Molecules, Vol. 25, Pages 1346: Effects of Exogenous Abscisic Acid on Bioactive Components and Antioxidant Capacity of Postharvest Tomato during Ripening Molecules doi: 10.3390/molecules25061346 Authors: Xiaoya Tao Qiong Wu Halah Aalim Li Li Linchun Mao Zisheng Luo Tiejin Ying Abscisic acid (ABA) is a phytohormone which is involved in the regulation of tomato ripening. In this research, the effects of exogenous ABA on the bioactive components and antioxidant capacity...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1344: Paper-Based Oil Barrier Packaging using Lignin-Containing Cellulose Nanofibrils
Molecules, Vol. 25, Pages 1344: Paper-Based Oil Barrier Packaging using Lignin-Containing Cellulose Nanofibrils Molecules doi: 10.3390/molecules25061344 Authors: Ali H. Tayeb Mehdi Tajvidi Douglas Bousfield Environmental and health concerns are driving the need for new materials in food packaging to replace poly- or perfluorinated compounds, aluminum layers, and petroleum-based polymers. Cellulose nanofibrils (CNF) have been shown by a number of groups to form excellent barrier...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1343: Improving Dissolution and Cytotoxicity by Forming Multidrug Crystals
Molecules, Vol. 25, Pages 1343: Improving Dissolution and Cytotoxicity by Forming Multidrug Crystals Molecules doi: 10.3390/molecules25061343 Authors: Xufei Bian Lan Jiang Jing Zhou Xiaoshu Guan Jingyu Wang Peng Xiang Junyi Pan Xiangnan Hu Both rosiglitazone and metformin have effects on blood glucose regulation and the proliferation of liver cancer cells. Combination therapy with these two drugs is common and effective for the treatment of diabetes in the clinic,...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1342: Classification of Red Wines Produced from Zweigelt and Rondo Grape Varieties Based on the Analysis of Phenolic Compounds by UPLC-PDA-MS/MS
Molecules, Vol. 25, Pages 1342: Classification of Red Wines Produced from Zweigelt and Rondo Grape Varieties Based on the Analysis of Phenolic Compounds by UPLC-PDA-MS/MS Molecules doi: 10.3390/molecules25061342 Authors: Anna Stój Ireneusz Kapusta Dorota Domagała The authentication of grape variety from which wine is produced is necessary for protecting a consumer from adulteration and false labelling. The aim of this study was to analyze phenolic compounds in red monovarietal...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1341: Polyphenols from Salix tetrasperma Impair Virulence and Inhibit Quorum Sensing of Pseudomonas aeruginosa
Molecules, Vol. 25, Pages 1341: Polyphenols from Salix tetrasperma Impair Virulence and Inhibit Quorum Sensing of Pseudomonas aeruginosa Molecules doi: 10.3390/molecules25061341 Authors: Islam Mostafa Hisham A. Abbas Mohamed L. Ashour Abdelaziz Yasri Assem M. El-Shazly Michael Wink Mansour Sobeh Bacterial resistance represents one of the emerging obstacles in plants, animals, and humans that impairs treatment with antibacterial agents. Targeting of the bacterial quorum...
Molecules
Mon Mar 16, 2020 02:00
Molecules, Vol. 25, Pages 1340: Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It
Molecules, Vol. 25, Pages 1340: Resistance of Gram-Negative Bacteria to Current Antibacterial Agents and Approaches to Resolve It Molecules doi: 10.3390/molecules25061340 Authors: Zeinab Breijyeh Buthaina Jubeh Rafik Karaman Antimicrobial resistance represents an enormous global health crisis and one of the most serious threats humans face today. Some bacterial strains have acquired resistance to nearly all antibiotics. Therefore, new antibacterial agents are crucially needed to...
Molecules
Mon Mar 16, 2020 02:00
Nanomaterials, Vol. 10, Pages 532: Real-Time In Vivo Imaging of Mouse Left Ventricle Reveals Fluctuating Movements of the Intercalated Discs
Nanomaterials, Vol. 10, Pages 532: Real-Time In Vivo Imaging of Mouse Left Ventricle Reveals Fluctuating Movements of the Intercalated Discs Nanomaterials doi: 10.3390/nano10030532 Authors: Fuyu Kobirumaki-Shimozawa Tomohiro Nakanishi Togo Shimozawa Takako Terui Kotaro Oyama Jia Li William E. Louch Shin’ichi Ishiwata Norio Fukuda Myocardial contraction is initiated by action potential propagation through the conduction system of the heart. It has been thought...
Nanomaterials
Mon Mar 16, 2020 02:00
Nanomaterials, Vol. 10, Pages 531: Carbonized Dehydroascorbic Acid: Aim for Targeted Repair of Graphene Defects and Bridge Connection of Graphene Sheets with Small Size
Nanomaterials, Vol. 10, Pages 531: Carbonized Dehydroascorbic Acid: Aim for Targeted Repair of Graphene Defects and Bridge Connection of Graphene Sheets with Small Size Nanomaterials doi: 10.3390/nano10030531 Authors: Jing Li Jinfeng Lai Jialiang Liu Rubai Lei Yuxun Chen The thermal dissipation issue of electronics devices becomes increasingly prominent as they evolve to smaller sizes and more complicated structures. Therefore, the development of materials with excellent...
Nanomaterials
Mon Mar 16, 2020 02:00
Nutrients, Vol. 12, Pages 786: Is Adolescents’ Food Intake Associated with Exposure to the Food Intake of Their Mothers and Best Friends?
Nutrients, Vol. 12, Pages 786: Is Adolescents’ Food Intake Associated with Exposure to the Food Intake of Their Mothers and Best Friends? Nutrients doi: 10.3390/nu12030786 Authors: Nina van den Broek Junilla. K. Larsen Maaike Verhagen William J. Burk Jacqueline M. Vink Both mothers’ and best friends’ food intake are associated with adolescents’ food intake, but they are rarely investigated simultaneously. In this study, we tested the associations...
Nutrients
02:00
Nutrients, Vol. 12, Pages 785: Intradialytic Nutrition and Hemodialysis Prescriptions: A Personalized Stepwise Approach
Nutrients, Vol. 12, Pages 785: Intradialytic Nutrition and Hemodialysis Prescriptions: A Personalized Stepwise Approach Nutrients doi: 10.3390/nu12030785 Authors: Piccoli Lippi Fois Gendrot Nielsen Vigreux Chatrenet D’Alessandro Cabiddu Cupisti Dialysis and nutrition are two sides of the same coin—dialysis depurates metabolic waste that is typically produced by food intake. Hence, dietetic restrictions are commonly imposed in order to limit...
Nutrients
Mon Mar 16, 2020 02:00
Nutrients, Vol. 12, Pages 784: Comparative Bioavailability of Different Coenzyme Q10 Formulations in Healthy Elderly Individuals
Nutrients, Vol. 12, Pages 784: Comparative Bioavailability of Different Coenzyme Q10 Formulations in Healthy Elderly Individuals Nutrients doi: 10.3390/nu12030784 Authors: Igor Pravst Juan Carlos Rodríguez Aguilera Ana Belen Cortes Rodriguez Janja Jazbar Igor Locatelli Hristo Hristov Katja Žmitek Coenzyme Q10 (CoQ10) plays a central role in mitochondrial oxidative phosphorylation. Several studies have shown the beneficial effects of dietary CoQ10 supplementation, particularly...
Nutrients
Mon Mar 16, 2020 02:00
Nutrients, Vol. 12, Pages 783: Vitamin D Supplementation in Multiple Sclerosis: A Critical Analysis of Potentials and Threats
Nutrients, Vol. 12, Pages 783: Vitamin D Supplementation in Multiple Sclerosis: A Critical Analysis of Potentials and Threats Nutrients doi: 10.3390/nu12030783 Authors: Julia Feige Tobias Moser Lara Bieler Kerstin Schwenker Larissa Hauer Johann Sellner Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative disease of the central nervous system (CNS). In recent years, vitamin D has gained attention, as low serum levels are suspected to increase...
Nutrients
Mon Mar 16, 2020 02:00
Nutrients, Vol. 12, Pages 782: Postprandial Glycemia, Insulinemia, and Antioxidant Status in Healthy Subjects after Ingestion of Bread made from Anthocyanin-Rich Riceberry Rice
Nutrients, Vol. 12, Pages 782: Postprandial Glycemia, Insulinemia, and Antioxidant Status in Healthy Subjects after Ingestion of Bread made from Anthocyanin-Rich Riceberry Rice Nutrients doi: 10.3390/nu12030782 Authors: Charoonsri Chusak Porntip Pasukamonset Praew Chantarasinlapin Sirichai Adisakwattana Riceberry rice, a gluten-free grain, contains many nutrient components, including carbohydrates, proteins, certain fatty acids, and micronutrients, as well as bioactive non-nutrient...
Nutrients
Mon Mar 16, 2020 02:00
Particles, Vol. 3, Pages 234-244: Heavy Baryon Spectroscopy in the Relativistic Quark Model
Particles, Vol. 3, Pages 234-244: Heavy Baryon Spectroscopy in the Relativistic Quark Model Particles doi: 10.3390/particles3010019 Authors: Rudolf N. Faustov Vladimir O. Galkin Masses of heavy baryons are calculated in the framework of the relativistic quark-diquark picture and QCD. The obtained results are in good agreement with available experimental data including recent measurements by the LHCb Collaboration. Possible quantum numbers of excited heavy baryon states are discussed.
Particles
Mon Mar 16, 2020 02:00
Pathogens, Vol. 9, Pages 218: Intelligent Mechanisms of Macrophage Apoptosis Subversion by Mycobacterium
Pathogens, Vol. 9, Pages 218: Intelligent Mechanisms of Macrophage Apoptosis Subversion by Mycobacterium Pathogens doi: 10.3390/pathogens9030218 Authors: Abdalla Ejaz Mahjoob Alameen Abosalif Elamir Mousa Macrophages are one of the first innate defense barriers and play an indispensable role in communication between innate and adaptive immune responses, leading to restricted Mycobacterium tuberculosis (Mtb) infection. The macrophages can undergo programmed cell...
Pathogens
Mon Mar 16, 2020 02:00
Pathogens, Vol. 9, Pages 217: Description of Virulent Factors and Horizontal Gene Transfers of Keratitis-Associated Amoeba Acanthamoeba Triangularis by Genome Analysis
Pathogens, Vol. 9, Pages 217: Description of Virulent Factors and Horizontal Gene Transfers of Keratitis-Associated Amoeba Acanthamoeba Triangularis by Genome Analysis Pathogens doi: 10.3390/pathogens9030217 Authors: Hasni Andréani Colson La Scola Acanthamoeba triangularis strain SH 621 is a free-living amoeba belonging to Acanthamoeba ribo-genotype T4. This ubiquitous protist is among the free-living amoebas responsible for Acanthamoeba keratitis, a severe infection of...
Pathogens
Mon Mar 16, 2020 02:00
Pharmaceuticals, Vol. 13, Pages 46: Products Derived from Buchenavia tetraphylla Leaves Have In Vitro Antioxidant Activity and Protect Tenebrio molitor larvae against Escherichia coli-Induced Injury
Pharmaceuticals, Vol. 13, Pages 46: Products Derived from Buchenavia tetraphylla Leaves Have In Vitro Antioxidant Activity and Protect Tenebrio molitor larvae against Escherichia coli-Induced Injury Pharmaceuticals doi: 10.3390/ph13030046 Authors: Tiago Fonseca Silva José Robson Neves Cavalcanti Filho Mariana Mirelle Lima Barreto Fonsêca Natalia Medeiros dos Santos Ana Carolina Barbosa da Silva Adrielle Zagmignan Afonso Gomes Abreu Ana Paula Sant’Anna da Silva Vera...
Pharmaceuticals
Mon Mar 16, 2020 02:00
Pharmaceutics, Vol. 12, Pages 273: Reconciling Quality by Design and Transdermal Product Development
Pharmaceutics, Vol. 12, Pages 273: Reconciling Quality by Design and Transdermal Product Development Pharmaceutics doi: 10.3390/pharmaceutics12030273 Authors: Kenneth Miller Since my first exposure to the acronym ‘QbD’ more than ten years ago, I have been trying to understand exactly what QbD is and how I might incorporate its teachings into my twenty-odd years of experience developing transdermal systems. I feel I have made little progress since then. Eventually,...
Pharmaceutics
02:00
Pharmaceutics, Vol. 12, Pages 271: Predicting Pharmaceutical Particle Size Distributions Using Kernel Mean Embedding
Pharmaceutics, Vol. 12, Pages 271: Predicting Pharmaceutical Particle Size Distributions Using Kernel Mean Embedding Pharmaceutics doi: 10.3390/pharmaceutics12030271 Authors: Daan Van Hauwermeiren Michiel Stock Thomas De De Beer Ingmar Nopens In the pharmaceutical industry, the transition to continuous manufacturing of solid dosage forms is adopted by more and more companies. For these continuous processes, high-quality process models are needed. In pharmaceutical wet granulation,...
Pharmaceutics
Mon Mar 16, 2020 02:00
Pharmaceutics, Vol. 12, Pages 272: On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development
Pharmaceutics, Vol. 12, Pages 272: On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development Pharmaceutics doi: 10.3390/pharmaceutics12030272 Authors: O’Dwyer Imanidis Box Reppas A small-scale biphasic dissolution setup and a small-scale dissolution-permeation (D-P) setup were evaluated for their usefulness in simulating the luminal precipitation of three lipophilic weak bases—dipyridamole,...
Pharmaceutics
Mon Mar 16, 2020 02:00
Pharmaceutics, Vol. 12, Pages 270: Preparation, Characterization, and In Vivo Pharmacokinetic Evaluation of Polyvinyl Alcohol and Polyvinyl Pyrrolidone Blended Hydrogels for Transdermal Delivery of Donepezil HCl
Pharmaceutics, Vol. 12, Pages 270: Preparation, Characterization, and In Vivo Pharmacokinetic Evaluation of Polyvinyl Alcohol and Polyvinyl Pyrrolidone Blended Hydrogels for Transdermal Delivery of Donepezil HCl Pharmaceutics doi: 10.3390/pharmaceutics12030270 Authors: Santosh Bashyal Chang Yell Shin Sang Min Hyun Sun Woo Jang Sangkil Lee Transdermal delivery systems are emerging platforms for the delivery of donepezil hydrochloride (DH) for treating Alzheimer’s...
Pharmaceutics
Mon Mar 16, 2020 02:00
Pharmaceutics, Vol. 12, Pages 269: Drug Delivery to the Posterior Segment of the Eye: Biopharmaceutic and Pharmacokinetic Considerations
Pharmaceutics, Vol. 12, Pages 269: Drug Delivery to the Posterior Segment of the Eye: Biopharmaceutic and Pharmacokinetic Considerations Pharmaceutics doi: 10.3390/pharmaceutics12030269 Authors: Rubén Varela-Fernández Victoria Díaz-Tomé Andrea Luaces-Rodríguez Andrea Conde-Penedo Xurxo García-Otero Asteria Luzardo-Álvarez Anxo Fernández-Ferreiro Francisco J. Otero-Espinar The treatment of the posterior-segment ocular diseases, such as age-related eye diseases (AMD)...
Pharmaceutics
Mon Mar 16, 2020 02:00

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