Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00327A, Critical Review Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maria Cuartero, Noemi Colozza, Bibiana María Fernández-Pérez, Gaston A. CrespoThe monitoring of ammonium ion concentration has claimed the attention of researchers from multiple fields, being a crucial parameter for environmental and biomedical purposes. For example, ammonium is considered a...The content of this...
Thu Mar 12, 2020 02:00
Publication date: Available online 12 March 2020Source: Journal of the American College of SurgeonsAuthor(s): Susan L. Gearhart, Eric M. Do, Oluwafemi Owodunni, Alodia A. Gabre-Kidan, Thomas Magnuson
Thu Mar 12, 2020 12:35
Related ArticlesValproic acid attenuates CCR2-dependent tumor infiltration of monocytic myeloid-derived suppressor cells, limiting tumor progression. Oncoimmunology. 2020;9(1):1734268 Authors: Xie Z, Ikegami T, Ago Y, Okada N, Tachibana M Abstract Myeloid-derived suppressor cells (MDSCs) are immunosuppressive cells that promote tumor progression by inhibiting anti-tumor immunity and may be the cause of patient resistance to immune checkpoint inhibitors...
Thu Mar 12, 2020 12:34
Related ArticlesDeep neural network classification based on somatic mutations potentially predicts clinical benefit of immune checkpoint blockade in lung adenocarcinoma. Oncoimmunology. 2020;9(1):1734156 Authors: Peng J, Zou D, Gong W, Kang S, Han L Abstract Although several biomarkers have been proposed to predict the response of patients with lung adenocarcinoma (LUAD) to immune checkpoint blockade (ICB) therapy, existing challenges such as test...
Thu Mar 12, 2020 12:34
Related ArticlesA TP53-associated gene signature for prediction of prognosis and therapeutic responses in lung squamous cell carcinoma. Oncoimmunology. 2020;9(1):1731943 Authors: Xu F, Lin H, He P, He L, Chen J, Lin L, Chen Y Abstract The tumor-suppressor gene tumor protein p53 (TP53) is one of the most commonly mutated genes in human lung cancer, and TP53 mutations are associated with a worsened prognosis and causes resistance to cancer therapy....
Thu Mar 12, 2020 12:34
Related ArticlesLactate dehydrogenase: a marker of diminished antitumor immunity. Oncoimmunology. 2020;9(1):1731942 Authors: Van Wilpe S, Koornstra R, Den Brok M, De Groot JW, Blank C, De Vries J, Gerritsen W, Mehra N Abstract Lactate dehydrogenase (LDH) levels are inversely related with response to checkpoint inhibitors. Elevated LDH levels are the product of enhanced glycolytic activity of the tumor and tumor necrosis due to hypoxia, the latter...
Thu Mar 12, 2020 12:34
Related ArticlesA non-linear association between blood tumor mutation burden and prognosis in NSCLC patients receiving atezolizumab. Oncoimmunology. 2020;9(1):1731072 Authors: Nie W, Qian J, Xu MD, Gu K, Qian FF, Hu MJ, Lu J, Gan L, Zhang XY, Cao SH, Li JW, Wang Y, Zhang B, Wang SY, Hu F, Li CH, Zhong H, Han BH Abstract A significant association between high blood-based tumor mutational burden (bTMB) and improved progression-free survival (PFS) was...
Thu Mar 12, 2020 12:34
Related ArticlesOncolytic poxvirus CF33-hNIS-ΔF14.5 favorably modulates tumor immune microenvironment and works synergistically with anti-PD-L1 antibody in a triple-negative breast cancer model. Oncoimmunology. 2020;9(1):1729300 Authors: Chaurasiya S, Yang A, Kang S, Lu J, Kim SI, Park AK, Sivanandam V, Zhang Z, Woo Y, Warner SG, Fong Y Abstract Triple-negative breast cancer is the most aggressive subtype of breast cancer and is difficult to treat....
Thu Mar 12, 2020 12:34
Related ArticlesProphylactic and therapeutic antileukemic effects induced by the AAC-11-derived Peptide RT53. Oncoimmunology. 2020;9(1):1728871 Authors: Habault J, Kaci A, Pasquereau-Kotula E, Fraser C, Chomienne C, Dombret H, Braun T, Pla M, Poyet JL Abstract Despite considerable progress, the treatment of acute leukemia continues to be a challenge for a significant majority of patients. Using a well-characterized preclinical mouse model of acute...
Thu Mar 12, 2020 12:34
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Thu Mar 12, 2020 12:34
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Thu Mar 12, 2020 12:34
Related ArticlesBarriers to Effective Transfusion Practices in Limited-Resource Settings: From Infrastructure to Cultural Beliefs. World J Surg. 2020 Mar 10;: Authors: Mohammed AD, Ntambwe P, Crawford AM Abstract BACKGROUND: Surgery and anesthesia are indivisible parts of health care, but safe and timely care requires more than operating rooms and skilled providers. One vital component of a functional surgical system is reliable blood transfusion. While...
Thu Mar 12, 2020 12:32
Related ArticlesEpidemiological Comparisons and Risk Factors for Pre-hospital and In-Hospital Mortality Following Traumatic Injury in Malawi. World J Surg. 2020 Mar 10;: Authors: Purcell LN, Mulima G, Reiss R, Gallaher J, Charles A Abstract BACKGROUND: In sub-Saharan Africa, trauma is a leading cause of mortality in people less than 45 years. Injury mechanism and cause of death are difficult to characterize in the absence of pre-hospital care and a trauma...
Thu Mar 12, 2020 12:32
Related ArticlesSurgical Training Throughout Africa: A Review of Operative Case Volumes at Multiple Training Centers. World J Surg. 2020 Mar 10;: Authors: Parker RK, Topazian HM, Ndegwa W, Chesang P, Strain S, Thelander K, Parker AS, Riviello R Abstract BACKGROUND: Adequate surgical training is paramount to produce competent surgeons to address the global burden of surgical disease. The Pan-African Academy of Christian Surgeons (PAACS) has general surgery...
Thu Mar 12, 2020 12:32
Related ArticlesAuthor's Reply: Single Dose Steroid Injection After Loss of Signal (LOS) During Thyroid Surgery is Effective to Recover Electric Signal Avoiding Vocal Cord Palsy and the Need of Staged Thyroidectomy: Prospective Evaluation on 702 Patients. World J Surg. 2020 Mar 10;: Authors: Donatini G, Danion J, Zerrweck C, Etienne P, Kraimps JL PMID: 32157401 [PubMed - as supplied by publisher]
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Thu Mar 12, 2020 12:32
Related ArticlesAdding myofibroblasts to the lacrimal pump. Acta Histochem. 2020 Mar 07;:151536 Authors: Bâră RI, Voinea LM, Vrapciu AD, Rusu MC Abstract The lacrimal sac (LS) empties in the nasolacrimal duct to drain the tears in the inferior nasal meatus. Different studies indicated the role of the lacrimal pump in the lacrimal drainage. Although controversial, the lacrimal pump mechanism is an extrinsic one, either active, or passive. An intrinsic...
Thu Mar 12, 2020 12:30
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Thu Mar 12, 2020 12:30
Related ArticlesWe need a functioning name for PNES: Consider dissociative seizures. Epilepsy Behav. 2020 Mar 08;105:107002 Authors: Kerr WT, Stern JM PMID: 32160585 [PubMed - as supplied by publisher]
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Related ArticlesImpact of Invasive EEG Monitoring and Resective Neurosurgical Treatment on the Quality of Life in Patients with Drug Resistant Epilepsy - Preliminary Results. Psychiatr Danub. 2019 Dec;31(Suppl 5):769-773 Authors: Mijatović D, Petelin Gadže Ž, Đerke F, Mrak G, Petrović R, Lekić A Abstract BACKGROUND: Neurosurgical treatment is one of important way to cure drug resistant epilepsy. After invasive EEG monitoring and the invasive neurosurgical...
Thu Mar 12, 2020 12:30
Related ArticlesFactors Associated with Good Seizure Control in Patients on Valproic Acid. Eurasian J Med. 2020 Feb;52(1):41-46 Authors: Ahmad M, Rahman AFA, Sapuan S Abstract Objective: This study aims to generate a reference range for valproic acid (VPA) in this cohort and determine the factors associated with good seizure control in patients taking this drug. Materials and Methods: We conducted a prospective, cohort, observational study among...
Thu Mar 12, 2020 12:30
Related ArticlesEfficacy and tolerability of brivaracetam in patients with intellectual disability and epilepsy. Acta Neurol Belg. 2020 Mar 10;: Authors: Gillis RME, Wammes-van der Heijden EA, Schelhaas HJ, Tan IY, Festen DAM, Majoie MHJM Abstract Patients with intellectual disability (ID) are often excluded from clinical trials, and little is known about the best approach to treat their epilepsy. Brivaracetam (BRV) is a new antiepileptic drug (AED)...
Thu Mar 12, 2020 12:30
Related ArticlesSalvinorin A Does Not Affect Seizure Threshold in Mice. Molecules. 2020 Mar 07;25(5): Authors: Socała K, Doboszewska U, Wlaź P Abstract The κ-opioid receptor has recently gained attention as a new molecular target in the treatment of many psychiatric and neurological disorders including epilepsy. Salvinorin A is a potent plant-derived hallucinogen that acts as a highly selective κ-opioid receptor agonist. It has unique structure and pharmacological...
Thu Mar 12, 2020 12:30
Related ArticlesExperimentally Induced Convulsive Seizures Are Modulated in Part by Zinc Ions through the Pharmacoresistant Cav2.3 Calcium Channel. Cell Physiol Biochem. 2020 Feb 19;54(2):180-194 Authors: Alpdogan S, Neumaier F, Hescheler J, Albanna W, Schneider T Abstract BACKGROUND/AIMS: Still in 1999 the first hints were published for the pharmacoresistant Cav2.3 calcium channel to be involved in the generation of epileptic seizures, as transcripts...
Thu Mar 12, 2020 12:30
Related ArticlesDrug Refractory Epilepsy - A Series of Lesions with Triple Pathology. Neurol India. 2019 Jul-Aug;67(4):1093-1096 Authors: Tandon V, Chandra PS, Singla R, Bajaj J, Kakkar A, Sharma MC, Mahapatra AK, Tripathi M Abstract The associations between gangliogliomas, dysembryoplastic neuroepithelial tumors (DNETs), and cortical dysplasias remain debatable. We report five cases of drug refractory epilepsy with temporal lobe lesions. On resection,...
Thu Mar 12, 2020 12:30
Related ArticlesNeed of Immediate Drug Reduction after Epilepsy Surgery - A Prospective Observational Study. Neurol India. 2019 Jul-Aug;67(4):1050-1053 Authors: Bajaj J, Chandra SP, Ramanujam B, Girishan S, Doddamani R, Tripathi M Abstract Background: Patients undergoing epilepsy surgery are on polytherapy. Drug tapering is usually done after 1 year in adults and after 6 months in children. Sometimes, drugs have to be altered during the perioperative...
Thu Mar 12, 2020 12:30
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Thu Mar 12, 2020 12:30
Related ArticlesQuality Care for People with Intellectual Disability and Advanced Dementia: Guidance on Service Provision. J Palliat Med. 2018 09;21(9):1344-1352 Authors: McCarron M, McCallion P, Watchman K, Janicki MP, Coppus A, Service K, Fortea J, Hogan M, Reilly E, Stemp S Abstract Purpose of Report: The International Summit on Intellectual Disability and Dementia (Glasgow, Scotland; October 2016) noted that advanced dementia can be categorized as...
Thu Mar 12, 2020 12:30
Allogeneic hematopoietic-cell transplantation is a mainstay of treatment for hematologic cancers, and the gut microbiota — the collection of archaea, bacteria, fungi, protists, and viruses that reside in the gastrointestinal tract — are emerging as a pivotal influence on its clinical course. Major…
Thu Mar 12, 2020 02:00
Worldwide, more than 500,000 cases of incident hepatocellular carcinoma are diagnosed each year, related primarily to chronic infection with hepatitis B or hepatitis C virus. Since the 1990s, the incidences of cirrhosis and hepatocellular carcinoma have increased dramatically in the United States…
Thu Mar 12, 2020 02:00
Related ArticlesDiagnostic Performance of a Combination of Shear Wave Elastography and B-Mode Ultrasonography in Differentiating Benign from Malignant Thyroid Nodules. Clin Exp Otorhinolaryngol. 2020 Mar 11;: Authors: Yeon EK, Sohn YM, Seo M, Kim EJ, Eun YG, Park WS, Yun SJ Abstract Objectives.: This study was conducted to compare clinicopathologic and radiologic factors between benign and malignant thyroid nodules and to evaluate the diagnostic performance...
Thu Mar 12, 2020 12:28
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Thu Mar 12, 2020 12:28
Related ArticlesPsychometric properties of the Breast Cancer Awareness Measurement among Chinese women: a cross-sectional study. BMJ Open. 2020 Mar 09;10(3):e035911 Authors: Liu N, Li P, Wang J, Chen DD, Sun WJ, Guo PP, Zhang XH, Zhang W Abstract OBJECTIVES: To perform the cross-cultural adaption of the Breast Cancer Awareness Measurement (BCAM) and to test its psychometric properties among Chinese women. DESIGN: This is a cross-sectional study....
Thu Mar 12, 2020 12:25
Related ArticlesFacilitators and barriers to the self-management of COPD: a qualitative study from rural Nepal. BMJ Open. 2020 Mar 09;10(3):e035700 Authors: Yadav UN, Lloyd J, Hosseinzadeh H, Baral KP, Dahal S, Bhatta N, Harris MF Abstract OBJECTIVE: To understand the facilitators and barriers to the self-management of chronic obstructive pulmonary disease (COPD) in rural Nepal. SETTINGS: Community and primary care centres in rural Nepal. ...
Thu Mar 12, 2020 12:25
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Thu Mar 12, 2020 12:25
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Thu Mar 12, 2020 12:25
Related ArticlesKnowledge and perspectives of the new National Cervical Screening Program: a qualitative interview study of North Queensland women-'I could be that one percent'. BMJ Open. 2020 Mar 09;10(3):e034483 Authors: Nagendiram A, Bidgood R, Banks J, Heal C Abstract OBJECTIVES: To investigate women's understanding and attitudes towards the National Cervical Screening Program (NCSP) and to explore methods to improve screening participation. ...
Thu Mar 12, 2020 12:25
Related ArticlesEvaluation of a complex integrated, cross-sectoral psycho-oncological care program (isPO): a mixed-methods study protocol. BMJ Open. 2020 Mar 09;10(3):e034141 Authors: Jenniches I, Lemmen C, Cwik JC, Kusch M, Labouvie H, Scholten N, Gerlach A, Stock S, Samel C, Hagemeier A, Hellmich M, Haas P, Hallek M, Pfaff H, Dresen A Abstract INTRODUCTION: International standards of care require the complete integration of psycho-oncological care...
Thu Mar 12, 2020 12:25
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Thu Mar 12, 2020 12:25
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