Τρίτη 29 Οκτωβρίου 2019


Tumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas.
Related ArticlesTumor Suppression of Ras GTPase-Activating Protein RASA5 through Antagonizing Ras Signaling Perturbation in Carcinomas. iScience. 2019 Oct 08;21:1-18 Authors: Li L, Fan Y, Huang X, Luo J, Zhong L, Shu XS, Lu L, Xiang T, Chan ATC, Yeo W, Chen C, Chan WY, Huganir RL, Tao Q Abstract Aberrant RAS signaling activation is common in cancers with even few Ras mutations, indicating alternative dysregulation other than genetic mutations. We identified...
Rare Cancers
12h
Benign pericardial schwannoma with massive pericardial effusion in a Chinese man: A case report.
Related ArticlesBenign pericardial schwannoma with massive pericardial effusion in a Chinese man: A case report. Echocardiography. 2019 Oct;36(10):1944-1946 Authors: Li C, Zhang J, Fan R, Chen L, Liu D, Lin H Abstract Primary cardiac neoplasms are rare, and the pericardial schwannoma has an even lower occurrence. We report a case of pericardial schwannoma in China, which is the eighth reported case adding to the existing literature on pericardial schwannoma,...
Rare Cancers
12h
Neurological Immune Related Adverse Events Associated with Nivolumab, Ipilimumab, and Pembrolizumab Therapy-Review of the Literature and Future Outlook.
Related ArticlesNeurological Immune Related Adverse Events Associated with Nivolumab, Ipilimumab, and Pembrolizumab Therapy-Review of the Literature and Future Outlook. J Clin Med. 2019 Oct 24;8(11): Authors: Möhn N, Beutel G, Gutzmer R, Ivanyi P, Satzger I, Skripu T Abstract Immune checkpoint inhibitor (ICI) therapy has revolutionized the management of various cancers with previously poor prognosis. Despite its great efficacy, the therapy is associated...
Rare Cancers
12h
Peculiar pathological, radiological and clinical features of skull base dedifferentiated chordomas. Results from a referral Center case series and literature review.
Related ArticlesPeculiar pathological, radiological and clinical features of skull base dedifferentiated chordomas. Results from a referral Center case series and literature review. Histopathology. 2019 Oct 25;: Authors: Asioli S, Zoli M, Guaraldi F, Sollini G, Bacci A, Gibertoni D, Ricci C, Morandi L, Pasquini E, Righi A, Mazzatenta D Abstract BACKGROUND: Dedifferentiated chordoma is an uncommon and incompletely characterized aggressive neoplasm. Only...
Rare Cancers
12h
Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer.
Related ArticlesComparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer. JAMA Netw Open. 2019 Oct 02;2(10):e1913968 Authors: Vaske OM, Bjork I, Salama SR, Beale H, Tayi Shah A, Sanders L, Pfeil J, Lam DL, Learned K, Durbin A, Kephart ET, Currie R, Newton Y, Swatloski T, McColl D, Vivian J, Zhu J, Lee AG, Leung SG, Spillinger A, Liu HY, Liang WS, Byron SA, Berens ME, Resnick AC, Lacayo N, Spunt SL, Rangaswami A, Huynh...
Rare Cancers
12h
Incidence of second primary malignancies in patients with thyroid cancer in the Turkish population
Related ArticlesIncidence of second primary malignancies in patients with thyroid cancer in the Turkish population Turk J Med Sci. 2019 Oct 24;49(5):1529-1533 Authors: Karaköse M, Çordan İ, Can M, Kocabaş M, Kulaksızoğlu M, Karakurt F Abstract Background/aim: Thyroid cancer is the most common endocrine malignancy. Recently the incidence has been increasing faster compared to other malignancies. Different studies have shown that the incidence...
Rare Cancers
12h
Synchronous Gastrointestinal Stromal Tumor and Ampullary Neuroendocrine Tumor in Association with Neurofibromatosis Type 1: A Report of Three Cases.
Related ArticlesSynchronous Gastrointestinal Stromal Tumor and Ampullary Neuroendocrine Tumor in Association with Neurofibromatosis Type 1: A Report of Three Cases. Korean J Gastroenterol. 2019 Oct 25;74(4):227-231 Authors: Park EK, Kim HJ, Lee YH, Koh YS, Hur YH, Cho CK Abstract Neurofibromatosis type 1 (NF1) is an autosomal dominant hereditary disorder. The pathogenesis of NF1 is suggested to be an alteration of the NF-1 gene, which normally functions...
Rare Cancers
12h
Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.
Related ArticlesAtypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer. Cancer Discov. 2019 Oct 24;: Authors: Hobbs GA, Baker NM, Miermont AM, Thurman RD, Pierobon M, Tran TH, Anderson AO, Waters AM, Diehl JN, Papke B, Hodge RG, Klomp JE, Goodwin CM, DeLiberty JM, Wang J, Ng RWS, Gautam P, Bryant KL, Esposito D, Campbell SL, Petricoin EF, Simanshu DK, Aguirre AJ, Wolpin BM, Wennerberg K, Rudloff U, Cox AD, Der CJ Abstract...
Rare Cancers
12h
[Treatment strategy for infants with acute lymphoblastic leukemia].
Related Articles[Treatment strategy for infants with acute lymphoblastic leukemia]. Rinsho Ketsueki. 2019;60(9):1317-1323 Authors: Miyamura T Abstract Acute lymphoblastic leukemia (ALL) in infants under 1 is a rare and dismal disease. It is associated with a unique and specific biology, and 80% of cases harbor a KMT2A (MLL) gene rearrangement (KMT2A-r). In contrast to ALL in older children, with a survival rate of 80% or more, the prognosis of infant...
Rare Cancers
12h
Cerebellar Squamous Cell Carcinoma Due to Malignant Transformation of Cerebellopontine Angle Epidermoid Cyst, Report an Interesting Case and Review the Literature.
Related ArticlesCerebellar Squamous Cell Carcinoma Due to Malignant Transformation of Cerebellopontine Angle Epidermoid Cyst, Report an Interesting Case and Review the Literature. Prague Med Rep. 2019;120(2-3):95-102 Authors: Fereydonyan N, Taheri M, Kazemi F Abstract Malignant transformation of an epidermoid tumour is a rare entity that in almost all patients occurs at the same site of the primary lesion. We report a case of an epidermoid tumour with...
Rare Cancers
12h
Van der Woude Syndrome With a Novel Mutation in the IRF6 Gene.
Related ArticlesVan der Woude Syndrome With a Novel Mutation in the IRF6 Gene. J Craniofac Surg. 2019 Jul;30(5):e465-e467 Authors: Ural A, Bilgen F, Çakmakli S, Bekerecioğlu M Abstract Van der Woude syndrome (VWS) is a rare autosomal dominant disease, first reported in the literature in 1845 by Demarquay and subsequently thoroughly described in 1954 by Van der Woude. Van der Woude Syndrome is the most common form of syndromic orofacial clefting and...
Rare Cancers
12h
A Patient With a Protuberant Fibro-Osseous Lesion of the Temporal Bone.
Related ArticlesA Patient With a Protuberant Fibro-Osseous Lesion of the Temporal Bone. J Craniofac Surg. 2019 Jul;30(5):e453-e454 Authors: Maroun CA, Khalifeh I, Faddoul DS, Zaytoun G, Moukarbel RV Abstract Protuberant fibro-osseous lesion of the temporal bone, otherwise known as "Bullough's lesion", is a rare, benign exophytic fibro-osseous tumor. In this brief report, we present a case of a 61-year-old woman with a history of a right-sided skull...
Rare Cancers
12h
Presentation, Management, and Outcome of Lingual Thyroglossal Duct Cyst in Pediatric and Adult Populations.
Related ArticlesPresentation, Management, and Outcome of Lingual Thyroglossal Duct Cyst in Pediatric and Adult Populations. J Craniofac Surg. 2019 Jul;30(5):e442-e446 Authors: Li W, Ren YP, Shi YY, Zhang L, Bu RF Abstract Lingual thyroglossal duct cysts (LTDCs) are rare congenital anomalies of the neck. The authors described the presentation, management, and outcome of LTDC in pediatric and adult cases through a retrospective observational analysis...
Rare Cancers
12h
Eccrine porocarcinoma presenting as a recurrent wart.
Related ArticlesEccrine porocarcinoma presenting as a recurrent wart. Cutis. 2019 Mar;103(3):166-168 Authors: Torbeck R, Fazio J, Lee JB, Trufant J Abstract Eccrine porocarcinoma (EPC) is an exceedingly rare sweat gland tumor most commonly seen in older patients. Diagnosis of EPC is rare, representing a small percentage of cutaneous malignancies. In the absence of established guidelines, wide local excision (WLE) has traditionally been considered the...
Rare Cancers
12h
Gastrointestinal: Glomus tumor: A rare submucosal tumor of the stomach.
Related ArticlesGastrointestinal: Glomus tumor: A rare submucosal tumor of the stomach. J Gastroenterol Hepatol. 2019 05;34(5):815 Authors: Yoshida H, Asada M, Marusawa H PMID: 30665269 [PubMed - indexed for MEDLINE]
Rare Cancers
12h
Autologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes.
Related ArticlesAutologous cell lines from circulating colon cancer cells captured from sequential liquid biopsies as model to study therapy-driven tumor changes. Sci Rep. 2018 10 29;8(1):15931 Authors: Soler A, Cayrefourcq L, Mazard T, Babayan A, Lamy PJ, Assou S, Assenat E, Pantel K, Alix-Panabières C Abstract Circulating tumor cells (CTCs) are important clinical indicators for prognosis and treatment efficacy. However, CTC investigation is hampered...
Rare Cancers
12h
Lipochoristoma of the Internal Auditory Canal: Long-Term Surveillance.
Related ArticlesLipochoristoma of the Internal Auditory Canal: Long-Term Surveillance. Otolaryngol Head Neck Surg. 2019 02;160(2):359-360 Authors: Kedarisetty S, Surapaneni K PMID: 30322341 [PubMed - indexed for MEDLINE]
Rare Cancers
12h
Effects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells.
Related ArticlesEffects of dichloroacetate as single agent or in combination with GW6471 and metformin in paraganglioma cells. Sci Rep. 2018 09 11;8(1):13610 Authors: Florio R, De Lellis L, Veschi S, Verginelli F, di Giacomo V, Gallorini M, Perconti S, Sanna M, Mariani-Costantini R, Natale A, Arduini A, Amoroso R, Cataldi A, Cama A Abstract Paragangliomas (PGLs) are infiltrating autonomic nervous system tumors that cause important morbidity. At present,...
Rare Cancers
12h
First pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases.
Related ArticlesFirst pediatric experience of SL-401, a CD123-targeted therapy, in patients with blastic plasmacytoid dendritic cell neoplasm: report of three cases. J Hematol Oncol. 2018 05 02;11(1):61 Authors: Sun W, Liu H, Kim Y, Karras N, Pawlowska A, Toomey D, Kyono W, Gaynon P, Rosenthal J, Stein A Abstract BACKGROUND: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a highly aggressive hematological malignancy with extremely poor outcome....
Rare Cancers
12h
Unexplained ascites, a sign for neuroendocrine carcinoma.
Related ArticlesUnexplained ascites, a sign for neuroendocrine carcinoma. Med J Malaysia. 2018 02;73(1):60-62 Authors: Mohd Kamil MK, Ngiu CS, Md Isa N, Yaacob Y Y, Deborah Chew CH, Wong ZQ, Raja Ali RA Abstract Neuroendocrine neoplasm is an epithelial neoplasm with predominant neuroendocrine differentiation that can arise from many organs in the body. We reported a rare case of gastric neuroendocrine carcinoma which accounts for less than 1% of all...
Rare Cancers
12h
Curative lung metastectomy and complete pathological response after neo-adjuvant GEMOX chemotherapy for relapse fibrolamellar hepatocellular carcinoma.
Related ArticlesCurative lung metastectomy and complete pathological response after neo-adjuvant GEMOX chemotherapy for relapse fibrolamellar hepatocellular carcinoma. Med J Malaysia. 2018 02;73(1):46-48 Authors: Eng JY, Soon SY, Winnie Ling HY Abstract Fibrolamellar hepatocellular carcinoma (FL-HCC) is a rare variant of hepatocellular carcinoma. It is commonly reported in the younger population with no underlying chronic liver disease and free of viral...
Rare Cancers
12h
The First Case of Trypanosoma cruzi-Associated Retinitis in an Immunocompromised Host Diagnosed With Pan-Organism Polymerase Chain Reaction.
Related ArticlesThe First Case of Trypanosoma cruzi-Associated Retinitis in an Immunocompromised Host Diagnosed With Pan-Organism Polymerase Chain Reaction. Clin Infect Dis. 2018 06 18;67(1):141-143 Authors: Conrady CD, Hanson KE, Mehra S, Carey A, Larochelle M, Shakoor A Abstract We report the first case of Trypanosoma cruzi-associated retinitis diagnosed using 28s ribosomal DNA sequencing. The case highlights the utility of broad-range molecular diagnostics...
Rare Cancers
12h
Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial.
Related ArticlesUpdated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial. J Immunother Cancer. 2018 01 19;6(1):7 Authors: Kaufman HL, Russell JS, Hamid O, Bhatia S, Terheyden P, D'Angelo SP, Shih KC, Lebbé C, Milella M, Brownell I, Lewis KD, Lorch JH, von Heydebreck A, Hennessy M, Nghiem P Abstract BACKGROUND: Merkel cell carcinoma (MCC)...
Rare Cancers
12h

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Αρχειοθήκη ιστολογίου