Title: Halloween Can Be Frightful for Kids With Allergies, AsthmaCategory: Health NewsCreated: 10/26/2019 12:00:00 AMLast Editorial Review: 10/28/2019 12:00:00 AM (Source: MedicineNet Allergies General)
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bmj;367/oct29_17/l6267/FAF1faElizabeth Donald Hibbard started her professional life in Aberdeen, caring for sick children. She then turned to obstetrics and moved to London, where she met her future...
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Publication date: Available online 29 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Adeline Schwein, Yannick Georg
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Condition: Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionIntervention: Drug: larotrectinib(Vitrakvi, BAY2757556)Sponsor: BayerNot yet recruiting
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Condition: Squamous Cell CarcinomasIntervention: Other: solar irradiation and biopsiesSponsor: Centre Hospitalier Universitaire de NiceNot yet recruiting
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Publication date: Available online 28 October 2019Source: Prostaglandins & Other Lipid MediatorsAuthor(s): Gulsev Ozen, Chabha Benyahia, Yasmine Amgoud, Jigisha Patel, Heba M. Abd Elmoneim, Amel Bouhadoun, Sonia Yung, Fangfang Li, Youcef Mahieddine, Adam M. Silverstein, Yves Castier, Aurélie Cazes, Dan Longrois, Lucie H. Clapp, Xavier NorelAbstractPulmonary hypertension (PH) is characterized by an elevation of mean pulmonary artery pressure and it is classified into five groups. Among these groups,...
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Venöses Thoracic-outlet-Syndrom mit akuter Thrombose der V. subclavia (Paget-von-Schroetter-Syndrom)
Zusammenfassung Einleitung Der akute thrombotische Verschluss der V. subclavia oder V. axillaris wird in der Literatur als Paget-von-Schroetter-Syndrom bezeichnet. Es entsteht durch Mikrotraumen bzw. Intimaeinrisse der Vene und präsentiert sich klinisch mit venösem Rückstau, Prominenz der Oberarmvenen sowie infraklavikulärem oder axillärem Druckschmerz. Chronische Abflussstörungen der Vv. axillaris et subclavia aufgrund der anatomischen...
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Publication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): Jonathan M. Hanna, Danielle Temares, Fahmeed Hyder, Douglas L. Rothman, Robert K. Fulbright, Veronica L. Chiang, Daniel ComanAbstractBackground and purposeGiven increasing interest in laser interstitial thermotherapy (LITT) to treat brain tumor patients, we explored if examining multiple MRI contrasts per brain tumor patient undergoing surgery can impact predictive accuracy of survival post-LITT.Materials and methodsMRI...
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Publication date: Available online 29 October 2019Source: Magnetic Resonance ImagingAuthor(s): Jamal Sakhr, Blaine A. ChronikAbstractPassive reduction of gradient coil (GC) cylinder vibration depends critically on a thorough knowledge of how all pertinent physical parameters affect the vibration response. In this paper, we employ a recently introduced linear elastodynamic Z-coil model to study how the displacement response of a whole-body GC cylinder (subject to exclusive excitation of its Z-coil...
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Abstract IBD (inflammatory bowel disease) is a chronic, non‐specific, inflammatory gastrointestinal disease that mainly consists of Crohn's disease and ulcerative colitis. However, the etiology and pathogenesis of IBD are still unclear. B10 (IL‐10 producing regulatory B) cells, a subset of regulatory B cells, are known to contribute to intestinal homeostasis and the aberrant frequency of B10 cells is associated with IBD. We have recently reported that B10 cells can be induced by ManLAM (mannose‐capped...
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Linezolid has been traditionally been used for variety of illnesses and many adverse effects are well known. However, the triad of hypoglycemia, bone marrow suppression and hyponatremia in a single elderly patient is rarely described previously. Abstract What is known and objective Linezolid, a member of the oxazolidinone class of antibacterial drugs, is approved by the US Food and Drug Administration (FDA) for the treatment of vancomycin‐resistant Enterococcus faecium infections,...
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Publication date: Available online 29 October 2019Source: Archives des Maladies Professionnelles et de l'EnvironnementAuthor(s):
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Publication date: Available online 29 October 2019Source: Archives des Maladies Professionnelles et de l'EnvironnementAuthor(s):
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Abstract The posterior arch defects of the cervical spine are rare, and they arise out of deviations of the normal intrauterine development of the spine (4–8 weeks of development). The defects range from a cleft to the total agenesis of the posterior arch, with a reported prevalence of 4% and 0.15%, respectively. The pedicle agenesis is most frequently found in C6. A diagnosis is usually made after a traumatic incident in a previously asymptomatic patient. 35% of a patient’s current...
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The autumn brings a time in many parts of the northern hemisphere when festivals occur that traditionally offer a chance to celebrate the recent harvest season. In the United States and Canada, they are the holidays of Thanksgiving, in which families, friends, and colleagues often gather over a grand meal to give thanks for a variety of things such as good health, financial security, peace, and loved ones.
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(ISSN 0278-2391) is published monthly by Elsevier Inc, for the American Association of Oral and Maxillofacial Surgeons, 360 Park Avenue South, New York, NY 10010-1710. Business Office: 1600 John F. Kennedy Blvd, Ste 1800, Philadelphia, PA 19103-2899. Periodicals postage paid at New York, NY and additional mailing offices.
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Publication date: Available online 28 October 2019Source: Clinical BiochemistryAuthor(s): Chao Fang, Ziran Wang, Yuanyuan Dai, Wenjiao Chang, Lining Sun, Xiaoling MaAbstractBackgroundHuman neutrophil lipocalin (HNL) is used as a novel biomarker for infections. However, only a few studies have focused on the usefulness of HNL. The purpose of this study was to evaluate the diagnostic efficiency of HNL for identifying bacterial infections and to compare HNL with procalcitonin (PCT) and C-reactive protein...
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Publication date: Available online 28 October 2019Source: Clinical BiochemistryAuthor(s): Bogdan Cylwik, Ewa Gruszewska, Ewa Gindzienska-Sieskiewicz, Otylia Kowal-Bielecka, Lech ChrostekAbstractBackgroundIn the chronic inflammation process in the course of rheumatoid arthritis (RA), many alterations in the expression of plasma proteins, as well as their posttranslational modifications (including glycosylation) can occur. Taking into account the disturbances in protein glycosylation and the emerging...
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Publication date: Available online 28 October 2019Source: Clinical BiochemistryAuthor(s): Julita Kuczynska, Katarzyna Karas-Ruszczyk, Alicja Zakrzewska, Michał Dermanowski, Halina Sienkiewicz-Jarosz, Iwona Kurkowska-Jastrzebska, Przemysław Bienkowski, Magdalena Konopko, Monika Dominiak, Paweł MierzejewskiAbstractBackgroundIn some clinical situations (pregnancy, aging, drug resistance, toxicity), measurements of lamotrigine plasma levels may be reliable. Limited studies indicate that saliva and hair...
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Publication date: Available online 28 October 2019Source: Clinical BiochemistryAuthor(s): Pinelopi I. Artemaki, Aimilia D. Sklirou, Christos K. Kontos, Aikaterini-Anna Liosi, Despoina D. Gianniou, Iordanis N. Papadopoulos, Ioannis P. Trougakos, Andreas ScorilasAbstractObjectivesClusterin (CLU) is a multifunctional intra-/extra-cellular molecular chaperone with indications of serving as a promising prognostic biomarker for colorectal cancer (CRC). Several studies have examined the potential prognostic...
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Publication date: Available online 29 October 2019Source: Brazilian Journal of Anesthesiology (English Edition)Author(s): Anthony M.-H. Ho, Glenio B. Mizubuti
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Background: A case of peritoneal mesothelioma with an anaplastic lymphoma kinase (ALK) translocation was identified, and we conducted further studies to obtain diagnostic and therapeutic insights. We believe that this is the first report describing the cytology of this new tumor type. Case: A teenage woman was referred for severe pleural effusion. Enhanced computed tomography indicated an abdominal mass with ascites. Laparoscopy revealed tumor dissemination from the pelvis to the upper abdomen. Because...
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Publication date: Available online 28 October 2019Source: Cancer LettersAuthor(s): Ji Eun Kim, Baek Gil Kim, Yeonsue Jang, Suki Kang, Joo Hyun Lee, Nam Hoon ChoAbstractStroma-derived exosomal microRNA (exomiR) contributes to tumor progression, however, which remains poorly understood. In our study, we analyzed exomiRs from the cancer-associated fibroblast (CAF) and normal fibroblast (NF) isolated from an invasive ductal carcinoma (IDC) patient and found that the level of microRNA (miR)-4516 was approximately...
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Publication date: Available online 28 October 2019Source: Cancer LettersAuthor(s): Xiang Nan, Jiang Wang, Hao Cheng, Zheng Yin, Jianting Sheng, Bensheng Qiu, Ching C. Lau, Jason T. Yustein, Hong Zhao, Stephen T.C. WongAbstractEwing sarcoma (EwS) is an aggressive pediatric tumor treated with intensive cytotoxic chemotherapies. Overall survival for metastatic or relapsed disease is only 20-30%. Metformin has long been an attractive therapeutic option for EwS, but hypoxia limits its efficacy. Through...
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Two major studies demonstrate the effectiveness of problem-based learning and show that students, parents and teachers prefer such immersive learning techniques.
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Abstract Objective This study aimed to assess the level of aspartate aminotransaminase (AST), alanine aminotransaminase (ALT) and gamma-glutamyltransferase (GGT), and their association with type 2 diabetes mellitus in Northwest Ethiopia. Results Using a cross-sectional study, blood samples were collected from 192 Type 2 diabetes mellitus (T2DM)...
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Abstract Background Amorphous silica nanoparticles (SiO2 NPs) have been regarded as relatively benign nanomaterials, however, this widely held opinion has been questioned in recent years by several reports on in vitro and in vivo toxicity. Surface chemistry, more specifically the surface silanol content, has been identified as an important toxicity modulator for SiO2 NPs. Here, quantitative relationships between the silanol content...
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Abstract We previously reviewed our study of the pharmacological properties of cardiac Na+/Ca2+ exchange (NCX1) inhibitors among cardioprotective drugs, such as amiodarone, bepridil, dronedarone, cibenzoline, azimilide, aprindine, and benzyl-oxyphenyl derivatives (Watanabe et al. in J Pharmacol Sci 102:7–16, 2006). Since then we have continued our studies further and found that some cardioprotective drugs are NCX1 stimulators. Cardiac Na+/Ca2+ exchange current (INCX1) was stimulated...
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2019.10.14 | Thomas Johann Bauer and Peter von Möllendorff, eds. Die Briefe des Ignatios von Antiochia: Motive, Strategien, Kontexte. Millennium-Studien 72. Berlin: De Gruyter, 2018. pp. viii + 288. ISBN: 9783110604467. Review by Jonathon Lookadoo, Presbyterian University and Theological Seminary, Seoul, Republic of Korea. This volume edited by Bauer and von Möllendorff finds its origins in papers that were delivered to the twenty-fifth meeting of the Internationale Arbeitsgemeinschaft “Zweites...
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Loot boxes are items in video games that may be paid for with real-world money, but which contain randomised contents. There is a reliable correlation between loot box spending and problem gambling severity: the more money gamers spend on loot boxes, the more severe their problem gambling tends to be. However, it is unclear whether this link represents a case in which loot box spending causes problem gambling; a case in which the gambling-like nature of loot boxes cause problem gamblers to spend...
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Background The potential of unidentified microorganisms for academic and other applications is limitless. Plants have diverse microbial communities associated with their biomes. However, few studies have focused on the microbial community structure relevant to tree bark. Methods In this report, the microbial community structure of bark from the broad-leaved tree Acer palmatum was analyzed. Both a culture-independent approach using polymerase chain reaction (PCR) amplification and next...
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In 2010, the Conference of the Parties of the Convention on Biological Diversity agreed on the Strategic Plan for Biodiversity 2011–2020 in Aichi Prefecture, Japan. As this plan approaches its end, we discussed whether marine biodiversity and prediction studies were nearing the Aichi Targets during the 4th World Conference on Marine Biodiversity held in Montreal, Canada in June 2018. This article summarises the outcome of a five-day group discussion on how global marine biodiversity studies should...
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Background Soil aggregate-size classes, structural units of soil, are the important factors regulating soil organic carbon (SOC) turnover. However, the processes of litter C mineralization and storage in different aggregates-size classes are poorly understood, especially in the highly alkaline soils of north China. Here, we ask how four different aggregate sizes influence rates of C release (Cr) and SOC storage (Cs) in response to three types of plant litter added to an un-grazed natural grassland....
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Gene drives may be used in two ways to curtail vectored diseases. Both involve engineering the drive to spread in the vector population. One approach uses the drive to directly depress vector numbers, possibly to extinction. The other approach leaves intact the vector population but suppresses the disease agent during its interaction with the vector. This second application may use a drive engineered to carry a genetic cargo that blocks the disease agent. An advantage of the second application is...
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Tree aging is a new research area and has attracted research interest in recent years. Trees show extraordinary longevity; Platycladus orientalis L. (Cupressaceae) has a lifespan of thousands of years. Ancient trees are precious historical heritage and scientific research materials. However, tree aging and tree senescence have different definitions and are poorly understood. Since leaves are the most sensitive organ of a tree, we studied the structural response of leaves to tree age. Experiments...
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There is growing interest within regulatory agencies and toxicological research communities to develop, test, and apply new approaches, such as toxicogenomics, to more efficiently evaluate chemical hazards. Given the complexity of analyzing thousands of genes simultaneously, there is a need to identify reduced gene sets. Though several gene sets have been defined for toxicological applications, few of these were purposefully derived using toxicogenomics data. Here, we developed and applied a systematic...
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The number of people suffering from eye fatigue induced by visual display terminal (VDT) viewing is expected to increase in the modern world. Eye dysfunction is suggested to induce a decrease in cognitive function, at least in the long term. Furthermore, considering other previous findings, it may be reasonable to think that acute or relatively short-term eye dysfunction attenuates cognitive function for not only older but also young individuals. Hence, clarification of the effect of eye fatigue...
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Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Aurélie Daumas, Jeremy Magalon, Flore Delaunay, Maxime Abellan, Cécile Philandrianos, Florence Sabatier, Brigitte Granel, Guy Magalon
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Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Steven R. Cohen, Hayley Womack, Ali Ghanem
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Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Patrick Tonnard, Alexis Verpaele, Marcelo Carvas
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Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Shenglu Jiang, Yuping Quan, Jing Wang, Junrong Cai, Feng Lu
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Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Zhibin Yang, Ming Li, Shengyang Jin, Xinyu Zhang, Xuefeng Han, Facheng Li
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Histological examination of specimens from 22 donated elderly cadavers and 15 human fetuses revealed that the cricopharyngeus muscle (CPM) provided (1) posterior circular muscle fibers adjacent to the external aspect of the uppermost esophageal circular muscle and (2) a thin anterior sling connecting to that same muscle. Another thick lateral bundle of longitudinal muscle originated independently from a fascia covering the posterior crico‐arytenoideus muscle, extended laterally and posteriorly, and...
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Abstract We read Rannikko et al.’s article about proprotein convertase subtilisin/kexin type 9 (PCSK9) levels in patients with bacteremia [1] with great interest. In these patients PCSK9 levels were increased compared to healthy controls, which is in line with other published data and probably caused by the associated inflammatory response [2]. Interestingly, within the patient cohort, patients with lower PCSK9 levels were more likely to die at day 7, 28 and 90, which was surprising, because in...
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The billionaires Jeff Bezos and Elon Musk are driving the private space sector, however, they both have different motivations and goals for doing so. For Musk, space colonization is a matter of saving the human species — having a Plan B. For Bezos, he believes Earth can be saved and transformed into a "residential only" zone. Goods from industrial manufacturing would be outsourced from space colonies. One big concern regarding Bezos' plan is whether his company's presence in space would someday constitute...
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Burnout, a syndrome of emotional exhaustion, cynicism, and reduced effectiveness at work, has been linked to poor health, alcoholism, depression, and suicide in physicians. Burnout has adverse effects on patient care and the physician workforce, since burned-out physicians are more likely to report…
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Publication date: 13 January 2020Source: Behavioural Brain Research, Volume 377Author(s):
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Publication date: November 2019Source: European Journal of Radiology, Volume 120Author(s):
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