Τρίτη 29 Οκτωβρίου 2019


The Effect of Downsizing on the Normal Tricuspid Annulus
Abstract Tricuspid annuloplasty is a surgical procedure that cinches the valve’s annulus in order to reduce regurgitant blood flow. One of its critical parameters is the degree of downsizing. To provide insight into the effect of downsizing, we studied the annulus of healthy sheep during suture annuloplasty. To this end, we implanted fiduciary markers along the annulus of sheep and subsequently performed a DeVega suture annuloplasty. We performed five downsizing steps in each animal...
Latest Results for Annals of Biomedical Engineering
16h
Totally robotic soave pull-through procedure for Hirschsprung’s disease: lessons learned from 11 consecutive pediatric patients
Abstract Introduction Since Hirschsprung’s disease (HSCR) already proved to benefit from robotic surgery, we aimed at describing a wider series of patients with this rare disease who were operated on with a robotic approach. Patients and methods All consecutive HSCR patients who underwent totally robotic soave pull-through (TRSPT), between October 2015 and...
Latest Results for Pediatric Surgery International
14h
Complete horizontal gaze palsy due to bilateral paramedian pontine reticular formation involvement as a presentation of multiple sclerosis: a case report
Demyelinating central nervous system diseases include several disorders that multiple sclerosis (MS) is identified as the most common among them. Ocular movement disturbances are a typical presentation in MS p...
BMC Neurology - Latest Articles
14h
Motor impairment in a rare form of spastic paraplegia (Spoan syndrome): a 10-year follow-up
Spastic paraplegia, optic atrophy and neuropathy (Spoan syndrome) is an autosomal recessive disease with approximately 70 cases recorded in Brazil and Egypt.
BMC Neurology - Latest Articles
14h
Persistent trigeminal artery in a patient with posterior circulation stroke treated with rt-PA: case report
A persistent trigeminal artery (PTA) is a non-involuted embryonic vessel that connects the cavernous part of the internal carotid artery with the posterior circulation. In the adult it is associated with multi...
BMC Neurology - Latest Articles
14h
Sexual dysfunction and associated factors among patients with epilepsy at Amanuel Mental Specialty Hospital, Addis Ababa – Ethiopia
Many patients with chronic illness have sexual dysfunction that may be related to the condition itself, drug side effects, emotional sequel, or a combination of those factors. Patients with epilepsy are no exc...
BMC Neurology - Latest Articles
14h
Recurrent NUS1 canonical splice donor site mutation in two unrelated individuals with epilepsy, myoclonus, ataxia and scoliosis - a case report
We encountered two unrelated individuals suffering from neurological disorders, including epilepsy and scoliosis.
BMC Neurology - Latest Articles
14h
Low-level laser therapy improves pain in postcesarean section: a randomized clinical trial
Abstract This study aimed to evaluate the effect of low-level laser therapy (LLLT) on immediate postpartum pain relief during cesarean section. A randomized, parallel controlled trial was carried out. In total, 88 women with immediate postpartum were divided into 4 groups: control group (n = 22), placebo group (n = 22), experimental group I (n = 22, dose of 4 J/cm2), and experimental group II (n = 22, dose of 2 J/cm2). The pain measured by Numeric Rating Scale (NRS), algometry,...
Latest Results
14h
Correction to: Perioperative antibiotic prescribing in surgery departments of two private sector hospitals in Madhya Pradesh, India
Following publication of the original article (Machowska et al. 2019), the authors provided new footnotes for Table 1 and Table 2. The complete tables and updated footnotes are supplied below.
Latest Results for Perioperative Medicine
15h
MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2060-9MicroRNA-18a promotes cancer progression through SMG1 suppression and mTOR pathway activation in nasopharyngeal carcinoma
Cell Death and Disease - nature.com science feeds
15h
ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2064-5ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation
Cell Death and Disease - nature.com science feeds
15h
Correction: TLR4 signaling drives mesenchymal stromal cells commitment to promote tumor microenvironment transformation in multiple myeloma
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2059-2Correction: TLR4 signaling drives mesenchymal stromal cells commitment to promote tumor microenvironment transformation in multiple myeloma
Cell Death and Disease - nature.com science feeds
15h
Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2056-5Preparation of a new type 2 diabetic miniature pig model via the CRISPR/Cas9 system
Cell Death and Disease - nature.com science feeds
15h
Truncated <i>PPM1D</i> impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2057-4Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon
Cell Death and Disease - nature.com science feeds
15h
Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2055-6Ionizing radiation induces endothelial transdifferentiation of glioblastoma stem-like cells through the Tie2 signaling pathway
Cell Death and Disease - nature.com science feeds
15h
Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2045-8Tunneling nanotube-mediated intercellular vesicle and protein transfer in the stroma-provided imatinib resistance in chronic myeloid leukemia cells
Cell Death and Disease - nature.com science feeds
15h
MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer
Cell Death & Disease, Published online: 28 October 2019; doi:10.1038/s41419-019-2031-1MicroRNA-421 confers paclitaxel resistance by binding to the KEAP1 3′UTR and predicts poor survival in non-small cell lung cancer
Cell Death and Disease - nature.com science feeds
15h
Complexity in unclassified auto-inflammatory disease: a case report illustrating the potential for disease arising from the allelic burden of multiple variants
Abstract Background Despite recent advances in the diagnosis and understanding of many autoinflammatory diseases, there are still a great number of patients with phenotypes that do not fit any clinically- and/or genetically-defined disorders. Case presentation We describe a fourteen-year-old boy who presented at two and a half years of age with...
Latest Results for Pediatric Rheumatology
15h
Neuroglial stem cell-derived inflammatory pseudotumor (n-SCIPT): clinicopathologic characterization of a novel lesion of the lumbosacral spinal cord and nerve roots following intrathecal allogeneic stem cell intervention
http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=401&channel-name=Acta+Neuropathologica
16h
Looking at the Way We Walk Can Help Predict Cognitive Decline
“There is an emerging focus on the importance of assessing motor performance as well as cognitive performance to predict cognitive function loss,” explained guest editor Manuel Montero-Odasso, MD, PhD, Departments of Medicine (Geriatric Medicine), and Epidemiology and Biostatistics, Schulich School of Medicine & Dentistry, University of Western Ontario, and Gait and Brain Lab, Parkwood Institute, Lawson Health Research Institute, London, ON, Canada. “In the past two decades, large epidemiological...
IOS Press » News
16h
Expression dynamics of autophagy-related genes in the cattle tick Rhipicephalus microplus during embryonic development and under increasing larval starvation
Abstract Rhipicephalus microplus is a hematophagous ectoparasite that significantly affects parasitized cattle. As a one-host tick its entire life cycle consists of free-living and parasitic forms. Its extraordinary ability to survive during prolonged off-host periods has been related to the process of cytoplasmic degradation called autophagy. In order to deepen our understanding of this process during R. microplus non-parasitic stages, we determined the expression dynamics of...
Latest Results for Experimental and Applied Acarology
16h
Isolation, identification and plant growth promotion ability of endophytic bacteria associated with lupine root nodule grown in Tunisian soil
Abstract The present study aims to characterize nodule endophytic bacteria of spontaneous lupine plants regarding their diversity and their plant growth promoting (PGP) traits. The potential of PGPR inoculation was investigated to improve white lupine growth across controlled, semi-natural and field conditions. Lupinus luteus and Lupinus angustifolius nodules were shown inhabited by a large diversity of endophytes. Several endophytes harbor numerous plant growth promotion traits...
Latest Results for Archives/ /of/ /Microbiology
16h
Draft genome and description of Chryseobacterium phocaeense sp. nov.: a new bacterial species isolated from the sputum of a cystic fibrosis patient
Abstract Strain 6021061333T was isolated from the sputum of 16-year-old girl with cystic fibrosis following a pulmonary exacerbation. This bacterial strain could not be identified by our systematic MALDI-TOF mass spectrometry screening on a MicroFlex. This led to the sequencing of the 16S rRNA gene, which shows 97.83% sequence identity with Chryseobacterium kwangjuense strain KJ1R5T, the phylogenetic closely related type strain of a species with standing in nomenclature, which...
Latest Results for Archives/ /of/ /Microbiology
16h
Blastochloris tepida , sp. nov., a thermophilic species of the bacteriochlorophyll b -containing genus Blastochloris
Abstract A new taxon is created for the thermophilic purple nonsulfur bacterium previously designated as Rhodopseudomonas strain GI. Strain GI was isolated from a New Mexico (USA) hot spring microbial mat and grows optimally above 40 °C and to a maximum of 47 °C. Strain GI is a bacteriochlorophyll b-containing species of purple nonsulfur bacteria and displays a budding morphology, typical of species of the genus Blastochloris. Although resembling the species Blc. viridis in many...
Latest Results for Archives/ /of/ /Microbiology
16h
Novel magnetic nanocomposites combining selenium and iron oxide with excellent anti-biofilm properties
Abstract In this work, a novel magnetic nanocomposite combining selenium nanoparticles (SeNPs) with iron oxide nanoparticles (IONPs) was synthesized for the first time, in which the size of the iron oxide nanoparticles was 7–12 nm, and nearly spherical or rod-like selenium nanoparticles were obtained according to the different pH values of the reaction mixtures. Selenium incorporation into iron oxide nanoparticles was improved by using a chitosan coating with pentasodium triphosphate...
Latest Results for Journal of Materials Science
16h
Multivariate identification of extruded PLA samples from the infrared spectrum
Abstract Polylactic acid (PLA) is a biodegradable thermoplastic polymer that is presented as a good alternative to petroleum-derived plastics. Some of the major drawbacks of this material are its lack of thermal stability and rapid degradation in large-scale production; thus, special care must be taken during processing. To improve their properties, a reactive extrusion with a multi-epoxy chain extender (SAmfE) has been performed at pilot plant scale. The induced topological...
Latest Results for Journal of Materials Science
16h
Facile synthesis of hierarchical NiCoP nanowires@NiCoP nanosheets core–shell nanoarrays for high-performance asymmetrical supercapacitor
Abstract Transition metal phosphides have been regarded as reliable supercapacitor electrode materials and extensively researched. In this work, a facile three-step way has been taken to synthesize NiCoP@NiCoP core–shell nanoarrays directly grown on carbon cloth, which was used as a high-performance supercapacitor electrode. Compared with the NiCo-LDH precursor and NiCoP nanowire and NiCoP nanosheet, NiCoP@NiCoP core–shell composite shows higher electrochemical performance owing...
Latest Results for Journal of Materials Science
16h
Tensile testing of aged flexible unidirectional composite laminates for body armor
Abstract Flexible unidirectional (UD) composite laminates are commonly being used for ballistic-resistant body armor. These laminates comprise UD layers, each constructed by laminating thin layers of high-performance fibers held in place using very low modulus binder resins, with the fibers in each layer oriented parallel to each other. As these materials are used in body armor, it is important to investigate their long-term reliability, particularly with regard to exposure to...
Latest Results for Journal of Materials Science
16h
Effect of extrusion on the microstructure and corrosion behaviors of biodegradable Mg–Zn–Y–Gd–Zr alloy
Abstract Magnesium-based alloys presented great potential for biodegradable implant materials. However, the poor mechanical properties and high corrosion rate blocked its extensive application. In this study, a new biodegradable Mg–Zn–Y–Gd–Zr alloy was fabricated and extruded. The microstructure, corrosion morphologies and corrosion products film of the as-cast, homogenized and as-extruded alloys were characterized by optical micrographs, scanning electron microscopy, X-ray diffraction...
Latest Results for Journal of Materials Science
16h
Toxins, Vol. 11, Pages 625: The Sequence and a Three-Dimensional Structural Analysis Reveal Substrate Specificity Among Snake Venom Phosphodiesterases
Toxins, Vol. 11, Pages 625: The Sequence and a Three-Dimensional Structural Analysis Reveal Substrate Specificity Among Snake Venom Phosphodiesterases Toxins doi: 10.3390/toxins11110625 Authors: Ullah Ullah Ali Betzel ur Rehman (1) Background. Snake venom phosphodiesterases (SVPDEs) are among the least studied venom enzymes. In envenomation, they display various pathological effects, including induction of hypotension, inhibition of platelet aggregation, edema, and paralysis....
Toxins
16h
Toxins, Vol. 11, Pages 624: Analysis of the Use of Cylindrospermopsin and/or Microcystin-Contaminated Water in the Growth, Mineral Content, and Contamination of Spinacia oleracea and Lactuca sativa
Toxins, Vol. 11, Pages 624: Analysis of the Use of Cylindrospermopsin and/or Microcystin-Contaminated Water in the Growth, Mineral Content, and Contamination of Spinacia oleracea and Lactuca sativa Toxins doi: 10.3390/toxins11110624 Authors: Maria Llana-Ruiz-Cabello Angeles Jos Ana Cameán Flavio Oliveira Aldo Barreiro Joana Machado Joana Azevedo Edgar Pinto Agostinho Almeida Alexandre Campos Vitor Vasconcelos Marisa Freitas Cyanobacteria and cyanotoxins...
Toxins
18h
Toxins, Vol. 11, Pages 623: Venom Diversity and Evolution in the Most Divergent Cone Snail Genus Profundiconus
Toxins, Vol. 11, Pages 623: Venom Diversity and Evolution in the Most Divergent Cone Snail Genus Profundiconus Toxins doi: 10.3390/toxins11110623 Authors: Giulia Fassio Maria Vittoria Modica Lou Mary Paul Zaharias Alexander E. Fedosov Juliette Gorson Yuri I. Kantor Mandё Holford Nicolas Puillandre Profundiconus is the most divergent cone snail genus and its unique phylogenetic position, sister to the rest of the family Conidae, makes it a key taxon for examining...
Toxins
18h
Elevated expression of lncRNA SNHG15 in spinal tuberculosis: preliminary results
OBJECTIVE: The incidence and disability rate of spinal tuberculosis is high. The role of the expression of lncRNA SNHG15 in spinal tuberculosis and related mechanisms remains unclear.PATIENTS AND METHODS: Spinal tuberculosis and normal control tissues were collected, and lncRNA SNHG15 level was analyzed by real-time PCR. Mouse RAW264.7 cells were cultured and divided into control group, tuberculin (PPD) group, si-SNHG15, and PPD+ si-SNHG15 group followed by analysis of lncRNA SNHG15 level, cell proliferation...
European Review » Infectious Diseases
16h
Targeting miR-106-3p facilitates functional recovery via inactivating inflammatory microglia and interfering glial scar component deposition after neural injury
OBJECTIVE: The aim of this study was to elucidate whether the knockdown of microRNA-106-3p (miR-106-3p) could mediate the nerve regeneration and functional recovery after the spinal cord injury (SCI) and its potential mechanism.MATERIALS AND METHODS: Microglia were extracted from the cerebral cortex of the neonatal rats and cultured in vitro. Subsequently, biomarkers of M1-type and M2-type in microglia transfected with miR-106-3p inhibitor were measured. Furthermore, in vivo SCI model in rats was...
European Review » Neurology
16h
Article intro: Recent Advances in Robot-Assisted Surgery: Soft Tissue Contact Identification
A relevant article was published at the IEEE SACI2019 conference from Nagy et al., "Recent Advances in Robot-Assisted Surgery: Soft Tissue Contact Identification":"Robot-Assisted Minimally Invasive Surgery (RAMIS)   is   becoming   standard-of-care   in   western   medicine. RAMIS  offers  better  patient  outcome  compared  to  traditional open   surgery,   however,   the   surgeons’   ability   to   identify   the tissues  with  the  sense  of  touch  is  missing  from  most  robotic systems.   ...
SurgRob
16h
MiR-100 suppresses inflammatory activation of microglia and neuronal apoptosis following spinal cord injury via TLR4/NF-κB pathway
OBJECTIVE: This study aims to ascertain the effect of miR-100 on inflammation, apoptosis and functional rehabilitation after spinal cord injury (SCI) and the potential mechanism. MATERIALS AND METHODS: Firstly, microglia were extracted from 3-day-old neonatal rats and cultured for the purpose of inflammatory activation. Quantitative Real Time-Polymerase Chain Reaction (qRT-PCR) was conducted to detect the levels of miR-100, toll-like receptors 4 (TLR4) and nuclear factor-κB (NF-κB). Moreover, proteins...
European Review
16h
Sustained BMP-2 release and platelet rich fibrin synergistically promote tendon-bone healing after anterior cruciate ligament reconstruction in rat
OBJECTIVE: Anterior cruciate ligament (ACL) injuries which cause knee disabilities remain a clinical challenge due to the compromised tendon-bone repair. Multiple strategies have been proposed to treat the tendon-bone injuries, and the combination of these therapies hold great potential to achieve synergistic effects. MATERIALS AND METHODS: We built PLGA-BMP-2 (bone morphogenetic protein 2) system and confirmed the sustained release of BMP-2 both in vitro and in vivo. We then applied different therapies...
European Review
16h
LncRNA XIXT promotes osteogenic differentiation of bone mesenchymal stem cells and alleviates osteoporosis progression by targeting miRNA-30a-5p
OBJECTIVE: To uncover the role of XIXT in influencing the osteogenesis of hBMSCs by adsorbing microRNA-30a-5p (miRNA-30a-5p) to upregulate RUNX2. PATIENTS AND METHODS: The serum samples were collected from osteoporosis patients and normal people. hBMSCs were isolated from femoral head tissues. The serum levels of XIXT and miRNA-30a-5p were determined by quantitative Real Time-Polymerase Chain Reaction (qRT-PCR). The expression levels and activities of the osteogenic differentiation-related genes...
European Review
16h
LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma
OBJECTIVE: The functions of lncRNAs have been verified to be important biomarkers and regulators for diagnosis and treatment of human diseases. In osteosarcoma (OS), emerging evidence determined that lncRNA was associated with cell progression. However, due to the high incidence and recurrence rate of osteosarcoma, it is important to find an effective treatment for osteosarcoma. PATIENTS AND METHODS: QRT-PCR was used to detect the expression of ADPGK-AS1 and miR-542-3p in tissues and cells. Western...
European Review
16h

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