ObjectiveTo compare perinatal and maternal outcomes for Australian women with uncomplicated pregnancies according to planned place of birth, that is, in hospital labour wards, birth centres or at home. DesignA population-based retrospective design, linking and analysing routinely collected electronic data. Analysis comprised 2 tests and binary logistic regression for categorical data, yielding adjusted ORs. Continuous data were analysed using analysis of variance. SettingAll eight Australian states...
Mark above section as read
Abstract Background Blunt vertebral artery injury (BVAI) is a well-known potentially fatal complication of cervical spine injury. The condition is reported to be associated with vertebral fractures and cervical hyperextension. However, appropriate patient screening methods remain to be elucidated. This study aimed to identify the risk factors associated with BVAI in patients with cervical spine injury. ...
Mark above section as read
Abstract Background Rituximab has been demonstrated to be highly effective as a first‐line treatment for moderate to severe pemphigus; however, its high cost can be considered a limitation of this treatment. Objectives To compare direct costs of two regimens, rituximab + short‐term prednisone vs. prednisone alone, tested in the Ritux3 trial. Methods Patients were randomly assigned to receive 2 g of rituximab and two 500‐mg maintenance infusions at month 12 and month 18 along with...
Mark above section as read
Abstract Background GB001 is an oral antagonist of the prostaglandin D2 receptor that may inhibit recruitment and activation of airway eosinophils, reducing airway inflammation. Objective To assess GB001 safety, efficacy and pharmacokinetics from a Phase 2 study and explore the association between Type 2 biomarkers (fractional exhaled nitric oxide, blood eosinophils) and asthma control markers following GB001 administration. Methods A randomized, placebo‐control, double‐blind study...
Mark above section as read
New England Journal of Medicine, Ahead of Print.
Mark above section as read
An association between maternal diabetes, its medication and childhood cancer has not been previously explored in a registry‐based setting. With a case‐control design, we aimed to explore whether maternal diabetes is associated with an increased risk of childhood cancer in the offspring. Combining data from population‐based registries, we analyzed a total of 2,029 cases, i.e. persons with childhood cancer diagnosed under the age of 20 years between years 1996‐2014 and a total of 10,103 matched population...
Mark above section as read
Abstract The Amazon represents one of the most complex biomes in the world; however, the temporal variations in parasite community structure of fishes inhabiting this region remain poorly understood. Therefore, processes generating such variations are still unknown. The present study evaluated the long-term temporal variation of community structure of metazoan parasites of Pimelodus blochii collected in Iaco River, State of Acre (Southwestern Brazilian Amazon). A total of 196 parasites...
Mark above section as read
Abstract Although esophageal cancers have poor survival outcomes, evidence suggests that preoperative chemoradiation followed by surgery have improved survival outcomes. Minimally invasive surgery has equivalent oncological outcomes with less complication compared with open surgery, but there is insufficient data available in South Indian population. Our aim was to analyze the perioperative outcome and survival between minimally invasive and open transhiatal esophagectomy group....
5h
Mark above section as read
Human malaria has arguably affected more of human history than any other pathogen. Pregnant women have a higher risk of developing severe malaria as well as the risk of severe complications. We present a case of severe malaria in a pregnant patient from sub-Saharan Africa who was treated successfully with artesunate. A 28-year-old Nigerian woman with a 20-week intrauterine pregnancy presented with a five-day history of fever and diffuse joint pains. Evaluation of peripheral thin blood smear demonstrated...
Mark above section as read
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01996K, PaperTian Lu, Kai-Di Zhu, Chao Huang, Tian Wen, Yongjun jiao, Jin Zhu, Qing Zhang, Shou-Nian DingIn this work, we reported the detailed fabrication processes of two types of lateral flow immunochromatographic test strips (LFITS) by using colloidal gold gel and fluorescent CdTe quantum dots (QDs)...The content of this RSS Feed (c) The Royal Society of Chemistry
5h
Mark above section as read
Abstract Purpose Jejuno-ileal atresia remains the most common form of intestinal obstruction in the neonatal and infantile age group and has an incidence of 1:300 to 1:1500. Apple peel atresia (APA) is the rarest of the five described types. The morbidity and mortality of patients with APA managed at our institution are high, and we review our experience with this paper. We compared our outcomes with other developed and developing countries....
Mark above section as read
Abstract Background CircMYO10 is a circular RNA generated by back-splicing of gene MYO10 and is upregulated in osteosarcoma cell lines, but its functional role in osteosarcoma is still unknown. This study aimed to clarify the mechanism of circMYO10 in osteosarcoma. Methods CircMYO10 expression in 10 paired osteosarcoma and chondroma tissues...
5h
Mark above section as read
Biomater. Sci., 2019, Accepted ManuscriptDOI: 10.1039/C9BM00814D, PaperAbdollah Zakeri Siavashani, Javad Mohammadi, Katharina Maniura-Weber, Berna Senturk, Jhamak Nourmohammadi, Behnam Sadeghi, Lukas Huber, Markus RottmarImplantation of temporary and permanent biomaterials in the body leads to a foreign body reaction (FBR), which may adversely affect tissue repair processes and functional integration of the biomaterial. However,...The content of this RSS Feed (c) The Royal Society of Chemistry
Mark above section as read
The π‐electron donor naphtho[1,2‐b:5,6‐b′]dithiophene and its corresponding bis(hydroxymethyl) derivative (yellow) can act as guests for the π‐electron accepting cyclophane cyclobis(paraquat‐p‐phenylene) host (blue) and appear as promising building blocks for further development of electroactive molecular machines based on cyclobis(paraquat‐p‐phenylene). The synthesis and characterization of 2,7‐bis(hydroxymethyl)naphtho[1,2‐b:5,6‐b′]dithiophene 1 is described. Electrochemical investigations...
A series of perylenediimide (PDI)‐based multimers were synthesized using an original Suzuki‐Miyaura Coupling (SMC) reaction. The new approach considers the reaction between 1‐nitroPDI as the electrophilic reagent with a wide variety of boronic esters to reach PDI dimers, trimers and tetramers which are of particular interest as Non‐Fullerene Acceptors (NFAs) in organic photovoltaics. In this work, we compared the reactivity of 1‐bromoPDI and 1‐nitroPDI towards this pallado‐catalyzed cross‐coupling...
1,4,5‐Trisubstituted 1,2,3‐triazoles and 1,2,3‐triazole‐fused isoindolines are synthesized by a sustainable Pd‐catalyzed direct arylation reaction performed under solvent‐free conditions and in the presence of a recyclable heterogeneous catalyst. Fully substituted triazoles are synthesized by a sustainable direct arylation reaction performed under solvent‐free conditions and in the presence of a recyclable Pd/C heterogeneous catalyst. Exclusion of air as well as anhydrous conditions are not...
A first approach to 2‐iodocarbazoles by benzannulation of indole‐tethered propargyl alcohols has been developed at room temperature in an open‐flask reaction using iodine. This benzannulation protocol involves a regioselective 5‐endo‐spirocyclization followed by a selective 1,2‐alkenyl migration and aromatization cascade. Regioselective benzannulation reaction of indol‐3‐yl‐but‐3‐yn‐2‐ols to functionaly embellished 2‐iodocarbazoles is described for the first time using iodine at room temperature...
Intracyclic labeling with various heterocycles with carbon‐11 has been performed directly using cyclotron‐produced [11C]CO2. Many heterocycles have been obtained through a de novo cyclization in only 10 min without a preliminary transformation of [11C]CO2 Labeling of heterocycles with carbon‐11 is generally performed through peripheral functionalizations and more scarcely inside heterocyclic core. Such less common approach usually requires preliminary multi‐step synthesis of reactive species. Herein,...
C60 reacts under ambient light with o‐phthalaldehyde to afford an unanticipated C60‐phthalide derivative in 43 % yield. Alternatively, this hydrofullerene can be accessed via a novel tetrabutylammonium decatungstate photocatalyzed reaction of C60 with phthalides (4 examples). A new, simple, and rapid photochemical reaction of o‐phthalaldehyde with C60 has been disclosed. This reaction afforded exclusively the unanticipated C60‐phthalide derivative 11 in good yield. The formation of this product...
Total, asymmetric synthesis of (+)‐Paroxetine and (+)‐Femoxetine is reported. The key step is organocatalytic Michael addition of aldehydes to trans‐nitroalkenes realized in bath or continues flow. High efficiency and selectivity in the Michael addition was achieved by application of Wang resin‐supported Hayashi–Jørgensen catalyst. Total, asymmetric synthesis of (+)‐Paroxetine and (+)‐Femoxetine, selective serotonin reuptake inhibitors, used for the treatment of depression, anxiety, and panic...
Mark above section as read
Metal‐catalyzed hydrofunctionalization reactions of haloalkynes (chloro‐, bromo‐ and iodoalkynes) are reviewed, covering examples of the selective addition of C–H, O–H, N–H, S–H and X–H (X = halide) bonds. Metal‐catalyzed hydrofunctionalization reactions of alkynes, i.e. the addition of E–H units (E = heteroatom or carbon) across the C≡C bond, are of key importance in modern synthetic chemistry. In recent years, haloalkynes have been successfully involved in these types of transformations,...
Titanium(IV) alkoxido and alkoxido chlorido complexes supported by bis(arylimino)acenaphthene ligand dpp‐bian in different reduced forms were obtained and fully characterized. Benzoxido dichlorido titanium derivative (dpp‐bian)TiOBnCl2 proved to be an efficient catalyst for the living ROP of L‐lactide providing a polylactide in a highly controlled manner. A titanium(IV) alkoxido complex, (dpp‐bian)Ti(OBn)2 (2), as well as alkoxido chlorido complexes (dpp‐bian)TiCl(OCH2CH2OMe) (3) and (dpp‐bian)TiCl2OBn...
We discovered the eco‐friendly and fast strategy that mechanochemically synthesized Fe‐MIL‐88A MOF show hierarchical superstructures. The key finding is that the types of the additives during mechanochemical reaction influence on the morphology of MOFs, generating 3D superstructure and 1D nanorod. The synthesis of hierarchical or nanosized metal‐organic framework (MOF) superstructures is highly desirable. However, the development of synthetic methods for designed MOF structures via mechanochemical...
A layered hybrid perovskite belonging to the <110> series (m = 2 members), (FA)2(HEA)2Pb2Br8, (HEA, hydroxyethylammonium; FA, formamidinium) exhibits reversible mechanochromic luminescence properties, while for the first time PeLEDs based on such a <110> layered perovskite as active material are also demonstrated. A layered hybrid perovskite belonging to the <110> series, (FA)2(HEA)2Pb2Br8 (HEA+, hydroxyethylammonium; FA+, formamidinium) exhibits a bright green narrow emission...
Heterometallic cyano‐bridged spin‐crossover complexes form a large family of switchable compounds with different structural motives and diverse transition characteristics. Here we report on the hysteretic water‐dependent spin transitions found in the family of [Fe(pyridazine)2M(CN)4] frameworks (M = Ni, Pd, Pt). The work shows a perspective of 1,2‐diazine application for the design of switchable complexes. Heterometallic cyano‐bridged spin‐crossover complexes form a large family of switchable...
Mark above section as read
Mark above section as read
Abstract Conventional wheelchairs are used by people who can actuate their hand, but there are conditions that cause the user cannot operate the wheelchair, such as handicapped people and amputated arms. Hence, they need an assistant to operate the wheelchair, as we know those conditions are dependent on others. An intelligent wheelchair becomes a solution to this problem by tracking and following an assistant in front of a wheelchair; it uses a camera that has been embedded...
Abstract This paper presents a novel approach to the occlusion handling problem in depth estimation using three views. A solution based on modification of similarity cost function is proposed. During the depth estimation via optimization algorithms, like Graph Cuts, the similarity metric is constantly updated so that only non-occluded fragments in the side views are considered. At each iteration of the algorithm, non-occluded fragments are detected based on side view virtual...
Abstract Passive Global Navigation Satellite System (GNSS)-based Synthetic Aperture Radar (SAR), known as GNSS-SAR, is a recently developing SAR imaging system. Due to the restrictions of transmission power and long distance transmission between GNSS satellites and earth surface, the received signals can be very weak after reflections, in which a noisy GNSS-SAR image can be resulted in. In this study, a new imaging algorithm for GNSS-SAR objects signal detectability enhancement...
Abstract User experience has become the most reliable and trustworthy source for service providers to assess system performance. To fulfill customer requirements, service providers require an efficient quality of experience (QoE) estimation model. QoE is a subjective metric that deals with user perception and can vary dramatically due to various factors such as emotions, the degree of annoyance, past experience, and aesthetics. Moreover, subjective QoE evaluation is expensive...
Discriminative dictionary learning for retinal vessel segmentation using fusion of multiple features
Abstract In recent years, automated retinal vessel segmentation has become especially essential for the early detection of some ophthalmological and cardiovascular diseases. In this paper, we have presented a new retinal vessel segmentation method via discriminative dictionary learning using fusion of multiple features, which is able to capture both thick and thin vessel structures. In the training stage, we employ six different enhancement algorithms to obtain multiple complementary...
Abstract Edges and flat areas in the sinogram of low-dose X-ray computed tomography are difficult to distinguish. This lack of distinction leads to excessive smoothing in the sinogram restoration. To address this problem, we propose a sinogram restoration algorithm using the regularized Perona–Malik (P–M) equation with intuitionistic fuzzy entropy. Firstly, considering the sinogram fuzziness, a novel edge indicator function is constructed using both the gradient magnitude and...
Abstract The main problem to be addressed in this paper is on the high required computational powers of the existing fractional pixel location search algorithms. The current solution method is based on the computation of the phase shift of the power spectral densities of two consecutive frames of a video sequence. Since the probability density function of each frame of the video sequence is required for computing its power spectral density but it is unknown in the practical situation,...
Abstract This paper proposes a method for generating inter-frame video images based on spatial continuity generative adversarial networks (SC-GANs) to smooth the playing of low-frame rate videos and to clarify blurry image edges caused by the use of traditional methods to improve the video frame rate. Firstly, the auto-encoder is used as a discriminator and Wasserstein distance is applied to represent the difference between the loss distribution of the real sample and the generated...
Mark above section as read
Abstract As an emerging food-borne pathogen, Cronobacter species are ubiquitous in the food and environment. In order to know the characteristics of Cronobacter spp. from the environment, we isolated Cronobacter spp. from soil and water, and then studied the molecular typing and antibiotic resistance characteristics of these isolates. In 2016, 141 soil and water samples were collected from farms and Riverside Park in Beijing. Isolates were identified by real-time PCR, 16s rRNA...
Abstract A novel facultative anaerobic, Gram-stain-positive coccus, strain JS71T, was isolated from the human subgingival dental plaque of a periodontitis lesion. Phylogenetic analysis based on the 16S ribosomal RNA gene (16S rDNA) revealed that the strain belonged to the genus Streptococcus. The 16S rDNA sequence had high similarity with Streptococcus rubneri DSM 26920T (98.6%), Streptococcus parasanguinis ATCC 15912T (98.5%), and Streptococcus australis CCUG 45919T (98.3%)....
Abstract In the present study, EMA (ethidium monoazide) treatment was applied to a silty-sand reference soil prior to DNA extraction to enable a differentiation between dead and living cells. For this purpose, a reference soil was spiked with Listeria monocytogenes cells or cell equivalents, respectively. With the purpose of evaluating optimum treatment conditions, different EMA concentrations have been tested. However, the results remained largely inconclusive. Furthermore,...
Abstract The phenotypic heterogeneity in a large population arises because of fluctuation in microenvironments and stochastic gene expressions. In this report, we isolated two types of persistent sub-populations of Vibrio cholerae, one triggered by starvation and another by antibiotics. We characterised starvation-induced (E-cells) and antibiotic-induced (P-cell) persister cells for stress tolerance, colony morphology and toxin gene expressions. Both the sub-populations differ...
Abstract Imidacloprid (C9H10ClN5O2) is used as the most recommended type of insecticide in vegetable farming worldwide. Two types of bacteria (Methylobacterium radiotolerans and Microbacterium arthrosphaerae) were isolated from a corn farming field in the Thrace region of Turkey, and then consortia of these bacteria were prepared from equal volumes of 107 CFU/ml for each bacterium type. Imidacloprid remediation studies were carried out during 18 days in soil test units. The water...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου