Τρίτη 29 Οκτωβρίου 2019


Maternal and perinatal outcomes by planned place of birth in Australia 2000 - 2012: a linked population data study
ObjectiveTo compare perinatal and maternal outcomes for Australian women with uncomplicated pregnancies according to planned place of birth, that is, in hospital labour wards, birth centres or at home. DesignA population-based retrospective design, linking and analysing routinely collected electronic data. Analysis comprised 2 tests and binary logistic regression for categorical data, yielding adjusted ORs. Continuous data were analysed using analysis of variance. SettingAll eight Australian states...
BMJ Open recent issues
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The distance of cervical vertebral dislocation could be a risk factor for blunt vertebral artery injury after traumatic cervical spine injury
Abstract Background Blunt vertebral artery injury (BVAI) is a well-known potentially fatal complication of cervical spine injury. The condition is reported to be associated with vertebral fractures and cervical hyperextension. However, appropriate patient screening methods remain to be elucidated. This study aimed to identify the risk factors associated with BVAI in patients with cervical spine injury. ...
Latest Results for Acta Neurochirurgica
4h
Comparison of real costs in the French healthcare system in newly diagnosed pemphigus patients: first‐line treatment with rituximab versus standard corticosteroid regimen. Data of a national multicentre trial
Abstract Background Rituximab has been demonstrated to be highly effective as a first‐line treatment for moderate to severe pemphigus; however, its high cost can be considered a limitation of this treatment. Objectives To compare direct costs of two regimens, rituximab + short‐term prednisone vs. prednisone alone, tested in the Ritux3 trial. Methods Patients were randomly assigned to receive 2 g of rituximab and two 500‐mg maintenance infusions at month 12 and month 18 along with...
British Journal of Dermatology
4h
A Phase 2 Study to Evaluate the Safety, Efficacy and Pharmacokinetics of DP2 Antagonist GB001 and to Explore Biomarkers of Airway Inflammation in Mild to Moderate Asthma
Abstract Background GB001 is an oral antagonist of the prostaglandin D2 receptor that may inhibit recruitment and activation of airway eosinophils, reducing airway inflammation. Objective To assess GB001 safety, efficacy and pharmacokinetics from a Phase 2 study and explore the association between Type 2 biomarkers (fractional exhaled nitric oxide, blood eosinophils) and asthma control markers following GB001 administration. Methods A randomized, placebo‐control, double‐blind study...
Clinical & Experimental Allergy
4h
Final Analysis of a Trial of M72/AS01E Vaccine to Prevent Tuberculosis
New England Journal of Medicine, Ahead of Print.
http://www.nejm.org/action/showFeed?jc=nejm&type=etoc&feed=rss
4h
Maternal Diabetes and Risk of Childhood Cancer in the Offspring
An association between maternal diabetes, its medication and childhood cancer has not been previously explored in a registry‐based setting. With a case‐control design, we aimed to explore whether maternal diabetes is associated with an increased risk of childhood cancer in the offspring. Combining data from population‐based registries, we analyzed a total of 2,029 cases, i.e. persons with childhood cancer diagnosed under the age of 20 years between years 1996‐2014 and a total of 10,103 matched population...
International Journal of Cancer
5h
Long-term temporal variation in the parasite community structure of metazoans of Pimelodus blochii (Pimelodidae), a catfish from the Brazilian Amazon
Abstract The Amazon represents one of the most complex biomes in the world; however, the temporal variations in parasite community structure of fishes inhabiting this region remain poorly understood. Therefore, processes generating such variations are still unknown. The present study evaluated the long-term temporal variation of community structure of metazoan parasites of Pimelodus blochii collected in Iaco River, State of Acre (Southwestern Brazilian Amazon). A total of 196 parasites...
Latest Results for Parasitology Research
5h
Oncological Outcomes After Radical Esophagectomy from a Tertiary Cancer Center
Abstract Although esophageal cancers have poor survival outcomes, evidence suggests that preoperative chemoradiation followed by surgery have improved survival outcomes. Minimally invasive surgery has equivalent oncological outcomes with less complication compared with open surgery, but there is insufficient data available in South Indian population. Our aim was to analyze the perioperative outcome and survival between minimally invasive and open transhiatal esophagectomy group....
http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=13193&channel-name=Indian+Journal+of+Surgical+Oncology
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Severe Case of Plasmodium falciparum Malaria in a Pregnant Woman from Nigeria
Human malaria has arguably affected more of human history than any other pathogen. Pregnant women have a higher risk of developing severe malaria as well as the risk of severe complications. We present a case of severe malaria in a pregnant patient from sub-Saharan Africa who was treated successfully with artesunate. A 28-year-old Nigerian woman with a 20-week intrauterine pregnancy presented with a five-day history of fever and diffuse joint pains. Evaluation of peripheral thin blood smear demonstrated...
Case Reports in Infectious Diseases
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Rapid detection of Shiga Toxin type II by lateral flow immunochromatography test strips of colorimetry and fluorimetry
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01996K, PaperTian Lu, Kai-Di Zhu, Chao Huang, Tian Wen, Yongjun jiao, Jin Zhu, Qing Zhang, Shou-Nian DingIn this work, we reported the detailed fabrication processes of two types of lateral flow immunochromatographic test strips (LFITS) by using colloidal gold gel and fluorescent CdTe quantum dots (QDs)...The content of this RSS Feed (c) The Royal Society of Chemistry
Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)
5h
Jejuno-ileal atresia: its characteristics and peculiarities concerning apple peel atresia, focused on its treatment and outcomes as experienced in one of the leading South African academic centres
Abstract Purpose Jejuno-ileal atresia remains the most common form of intestinal obstruction in the neonatal and infantile age group and has an incidence of 1:300 to 1:1500. Apple peel atresia (APA) is the rarest of the five described types. The morbidity and mortality of patients with APA managed at our institution are high, and we review our experience with this paper. We compared our outcomes with other developed and developing countries....
Latest Results for Pediatric Surgery International
5h
CircMYO10 promotes osteosarcoma progression by regulating miR-370-3p/RUVBL1 axis to enhance the transcriptional activity of β-catenin/LEF1 complex via effects on chromatin remodeling
Abstract Background CircMYO10 is a circular RNA generated by back-splicing of gene MYO10 and is upregulated in osteosarcoma cell lines, but its functional role in osteosarcoma is still unknown. This study aimed to clarify the mechanism of circMYO10 in osteosarcoma. Methods CircMYO10 expression in 10 paired osteosarcoma and chondroma tissues...
http://link.springer.com/search.rss?facet-content-type=Article&facet-journal-id=12943&channel-name=Molecular+Cancer
5h
Silk based scaffolds with immunomodulatory capacity: anti-inflammatory effects of nicotinic acid
Biomater. Sci., 2019, Accepted ManuscriptDOI: 10.1039/C9BM00814D, PaperAbdollah Zakeri Siavashani, Javad Mohammadi, Katharina Maniura-Weber, Berna Senturk, Jhamak Nourmohammadi, Behnam Sadeghi, Lukas Huber, Markus RottmarImplantation of temporary and permanent biomaterials in the body leads to a foreign body reaction (FBR), which may adversely affect tissue repair processes and functional integration of the biomaterial. However,...The content of this RSS Feed (c) The Royal Society of Chemistry
RSC - Biomater. Sci. latest articles
5h
Naphtho[1,2‐b:5,6‐b′]dithiophene Building Blocks and their Complexation with Cyclobis(paraquat‐p‐phenylene)
The π‐electron donor naphtho[1,2‐b:5,6‐b′]dithiophene and its corresponding bis(hydroxymethyl) derivative (yellow) can act as guests for the π‐electron accepting cyclophane cyclobis(paraquat‐p‐phenylene) host (blue) and appear as promising building blocks for further development of electroactive molecular machines based on cyclobis(paraquat‐p‐phenylene). The synthesis and characterization of 2,7‐bis(hydroxymethyl)naphtho[1,2‐b:5,6‐b′]dithiophene 1 is described. Electrochemical investigations...
European Journal of Organic Chemistry
5h
Original Suzuki‐Miyaura Coupling using Nitro derivatives for the Synthesis of Perylenediimide‐based Multimers
A series of perylenediimide (PDI)‐based multimers were synthesized using an original Suzuki‐Miyaura Coupling (SMC) reaction. The new approach considers the reaction between 1‐nitroPDI as the electrophilic reagent with a wide variety of boronic esters to reach PDI dimers, trimers and tetramers which are of particular interest as Non‐Fullerene Acceptors (NFAs) in organic photovoltaics. In this work, we compared the reactivity of 1‐bromoPDI and 1‐nitroPDI towards this pallado‐catalyzed cross‐coupling...
European Journal of Organic Chemistry
5h
Direct Arylations via C–H Bond Functionalization of 1,2,3‐Triazoles by a Reusable Pd/C Catalyst Under Solvent‐Free Conditions
1,4,5‐Trisubstituted 1,2,3‐triazoles and 1,2,3‐triazole‐fused isoindolines are synthesized by a sustainable Pd‐catalyzed direct arylation reaction performed under solvent‐free conditions and in the presence of a recyclable heterogeneous catalyst. Fully substituted triazoles are synthesized by a sustainable direct arylation reaction performed under solvent‐free conditions and in the presence of a recyclable Pd/C heterogeneous catalyst. Exclusion of air as well as anhydrous conditions are not...
European Journal of Organic Chemistry
5h
An Expeditious Benzannulation Reaction of Indol‐3‐yl‐but‐3‐yn‐2‐ols to Substituted 2‐Iodocarbazoles via Domino 5‐endo Spirocyclization/Selective Vinyl Shift and Aromatization
A first approach to 2‐iodocarbazoles by benzannulation of indole‐tethered propargyl alcohols has been developed at room temperature in an open‐flask reaction using iodine. This benzannulation protocol involves a regioselective 5‐endo‐spirocyclization followed by a selective 1,2‐alkenyl migration and aromatization cascade. Regioselective benzannulation reaction of indol‐3‐yl‐but‐3‐yn‐2‐ols to functionaly embellished 2‐iodocarbazoles is described for the first time using iodine at room temperature...
European Journal of Organic Chemistry
5h
11C‐Labeling: Intracyclic Incorporation of Carbon‐11 into Heterocycles
Intracyclic labeling with various heterocycles with carbon‐11 has been performed directly using cyclotron‐produced [11C]CO2. Many heterocycles have been obtained through a de novo cyclization in only 10 min without a preliminary transformation of [11C]CO2 Labeling of heterocycles with carbon‐11 is generally performed through peripheral functionalizations and more scarcely inside heterocyclic core. Such less common approach usually requires preliminary multi‐step synthesis of reactive species. Herein,...
European Journal of Organic Chemistry
5h
Photochemical Reaction of o‐Phthalaldehyde with Fullerene C60: The Stimulus for the Phthalide Additions to C60
C60 reacts under ambient light with o‐phthalaldehyde to afford an unanticipated C60‐phthalide derivative in 43 % yield. Alternatively, this hydrofullerene can be accessed via a novel tetrabutylammonium decatungstate photocatalyzed reaction of C60 with phthalides (4 examples). A new, simple, and rapid photochemical reaction of o‐phthalaldehyde with C60 has been disclosed. This reaction afforded exclusively the unanticipated C60‐phthalide derivative 11 in good yield. The formation of this product...
European Journal of Organic Chemistry
5h
Total Asymmetric Synthesis of (+)‐Paroxetine and (+)‐Femoxetine
Total, asymmetric synthesis of (+)‐Paroxetine and (+)‐Femoxetine is reported. The key step is organocatalytic Michael addition of aldehydes to trans‐nitroalkenes realized in bath or continues flow. High efficiency and selectivity in the Michael addition was achieved by application of Wang resin‐supported Hayashi–Jørgensen catalyst. Total, asymmetric synthesis of (+)‐Paroxetine and (+)‐Femoxetine, selective serotonin reuptake inhibitors, used for the treatment of depression, anxiety, and panic...
European Journal of Organic Chemistry
5h
Metal‐Catalyzed Hydrofunctionalization Reactions of Haloalkynes
Metal‐catalyzed hydrofunctionalization reactions of haloalkynes (chloro‐, bromo‐ and iodoalkynes) are reviewed, covering examples of the selective addition of C–H, O–H, N–H, S–H and X–H (X = halide) bonds. Metal‐catalyzed hydrofunctionalization reactions of alkynes, i.e. the addition of E–H units (E = heteroatom or carbon) across the C≡C bond, are of key importance in modern synthetic chemistry. In recent years, haloalkynes have been successfully involved in these types of transformations,...
European Journal of Inorganic Chemistry
5h
Four‐ and Five‐Coordinate Titanium(IV) Complexes Supported by the dpp‐bian Ligand in ROP of L‐Lactide
Titanium(IV) alkoxido and alkoxido chlorido complexes supported by bis(arylimino)acenaphthene ligand dpp‐bian in different reduced forms were obtained and fully characterized. Benzoxido dichlorido titanium derivative (dpp‐bian)TiOBnCl2 proved to be an efficient catalyst for the living ROP of L‐lactide providing a polylactide in a highly controlled manner. A titanium(IV) alkoxido complex, (dpp‐bian)Ti(OBn)2 (2), as well as alkoxido chlorido complexes (dpp‐bian)TiCl(OCH2CH2OMe) (3) and (dpp‐bian)TiCl2OBn...
European Journal of Inorganic Chemistry
5h
3D‐Superstructured Networks Comprising Fe‐MIL‐88A Metal‐Organic Frameworks Under Mechanochemical Conditions
We discovered the eco‐friendly and fast strategy that mechanochemically synthesized Fe‐MIL‐88A MOF show hierarchical superstructures. The key finding is that the types of the additives during mechanochemical reaction influence on the morphology of MOFs, generating 3D superstructure and 1D nanorod. The synthesis of hierarchical or nanosized metal‐organic framework (MOF) superstructures is highly desirable. However, the development of synthetic methods for designed MOF structures via mechanochemical...
European Journal of Inorganic Chemistry
5h
Mechanochromic and Electroluminescence Properties of a Layered Hybrid Perovskite Belonging to the <110> Series
A layered hybrid perovskite belonging to the <110> series (m = 2 members), (FA)2(HEA)2Pb2Br8, (HEA, hydroxyethylammonium; FA, formamidinium) exhibits reversible mechanochromic luminescence properties, while for the first time PeLEDs based on such a <110> layered perovskite as active material are also demonstrated. A layered hybrid perovskite belonging to the <110> series, (FA)2(HEA)2Pb2Br8 (HEA+, hydroxyethylammonium; FA+, formamidinium) exhibits a bright green narrow emission...
European Journal of Inorganic Chemistry
5h
Pyridazine‐Supported Polymeric Cyanometallates with Spin Transitions
Heterometallic cyano‐bridged spin‐crossover complexes form a large family of switchable compounds with different structural motives and diverse transition characteristics. Here we report on the hysteretic water‐dependent spin transitions found in the family of [Fe(pyridazine)2M(CN)4] frameworks (M = Ni, Pd, Pt). The work shows a perspective of 1,2‐diazine application for the design of switchable complexes. Heterometallic cyano‐bridged spin‐crossover complexes form a large family of switchable...
European Journal of Inorganic Chemistry
5h
Human tracking by using multiple methods and weighted products
Abstract Conventional wheelchairs are used by people who can actuate their hand, but there are conditions that cause the user cannot operate the wheelchair, such as handicapped people and amputated arms. Hence, they need an assistant to operate the wheelchair, as we know those conditions are dependent on others. An intelligent wheelchair becomes a solution to this problem by tracking and following an assistant in front of a wheelchair; it uses a camera that has been embedded...
Latest Results for Signal, Image and Video Processing
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Depth estimation using modified cost function for occlusion handling
Abstract This paper presents a novel approach to the occlusion handling problem in depth estimation using three views. A solution based on modification of similarity cost function is proposed. During the depth estimation via optimization algorithms, like Graph Cuts, the similarity metric is constantly updated so that only non-occluded fragments in the side views are considered. At each iteration of the algorithm, non-occluded fragments are detected based on side view virtual...
Latest Results for Signal, Image and Video Processing
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Object detectability enhancement under weak signals for passive GNSS-based SAR
Abstract Passive Global Navigation Satellite System (GNSS)-based Synthetic Aperture Radar (SAR), known as GNSS-SAR, is a recently developing SAR imaging system. Due to the restrictions of transmission power and long distance transmission between GNSS satellites and earth surface, the received signals can be very weak after reflections, in which a noisy GNSS-SAR image can be resulted in. In this study, a new imaging algorithm for GNSS-SAR objects signal detectability enhancement...
Latest Results for Signal, Image and Video Processing
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Perceptual quality assessment of video using machine learning algorithm
Abstract User experience has become the most reliable and trustworthy source for service providers to assess system performance. To fulfill customer requirements, service providers require an efficient quality of experience (QoE) estimation model. QoE is a subjective metric that deals with user perception and can vary dramatically due to various factors such as emotions, the degree of annoyance, past experience, and aesthetics. Moreover, subjective QoE evaluation is expensive...
Latest Results for Signal, Image and Video Processing
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Discriminative dictionary learning for retinal vessel segmentation using fusion of multiple features
Abstract In recent years, automated retinal vessel segmentation has become especially essential for the early detection of some ophthalmological and cardiovascular diseases. In this paper, we have presented a new retinal vessel segmentation method via discriminative dictionary learning using fusion of multiple features, which is able to capture both thick and thin vessel structures. In the training stage, we employ six different enhancement algorithms to obtain multiple complementary...
Latest Results for Signal, Image and Video Processing
5h
Sinogram restoration for low-dose X-ray computed tomography using regularized Perona–Malik equation with intuitionistic fuzzy entropy
Abstract Edges and flat areas in the sinogram of low-dose X-ray computed tomography are difficult to distinguish. This lack of distinction leads to excessive smoothing in the sinogram restoration. To address this problem, we propose a sinogram restoration algorithm using the regularized Perona–Malik (P–M) equation with intuitionistic fuzzy entropy. Firstly, considering the sinogram fuzziness, a novel edge indicator function is constructed using both the gradient magnitude and...
Latest Results for Signal, Image and Video Processing
5h
Determination of fractional pixel location via an optimal group delay estimation approach
Abstract The main problem to be addressed in this paper is on the high required computational powers of the existing fractional pixel location search algorithms. The current solution method is based on the computation of the phase shift of the power spectral densities of two consecutive frames of a video sequence. Since the probability density function of each frame of the video sequence is required for computing its power spectral density but it is unknown in the practical situation,...
Latest Results for Signal, Image and Video Processing
5h
Inter-frame video image generation based on spatial continuity generative adversarial networks
Abstract This paper proposes a method for generating inter-frame video images based on spatial continuity generative adversarial networks (SC-GANs) to smooth the playing of low-frame rate videos and to clarify blurry image edges caused by the use of traditional methods to improve the video frame rate. Firstly, the auto-encoder is used as a discriminator and Wasserstein distance is applied to represent the difference between the loss distribution of the real sample and the generated...
Latest Results for Signal, Image and Video Processing
5h
Identification and Characterization of Cronobacter Strains Isolated from Environmental Samples
Abstract As an emerging food-borne pathogen, Cronobacter species are ubiquitous in the food and environment. In order to know the characteristics of Cronobacter spp. from the environment, we isolated Cronobacter spp. from soil and water, and then studied the molecular typing and antibiotic resistance characteristics of these isolates. In 2016, 141 soil and water samples were collected from farms and Riverside Park in Beijing. Isolates were identified by real-time PCR, 16s rRNA...
Latest Results for Current Microbiology
6h
Streptococcus koreensis sp. nov., Isolated from Human Subgingival Dental Plaque of Periodontitis Lesion
Abstract A novel facultative anaerobic, Gram-stain-positive coccus, strain JS71T, was isolated from the human subgingival dental plaque of a periodontitis lesion. Phylogenetic analysis based on the 16S ribosomal RNA gene (16S rDNA) revealed that the strain belonged to the genus Streptococcus. The 16S rDNA sequence had high similarity with Streptococcus rubneri DSM 26920T (98.6%), Streptococcus parasanguinis ATCC 15912T (98.5%), and Streptococcus australis CCUG 45919T (98.3%)....
Latest Results for Current Microbiology
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Spiking a Silty-Sand Reference Soil with Bacterial DNA: Limits and Pitfalls in the Discrimination of Live and Dead Cells When Applying Ethidium Monoazide (EMA) Treatment
Abstract In the present study, EMA (ethidium monoazide) treatment was applied to a silty-sand reference soil prior to DNA extraction to enable a differentiation between dead and living cells. For this purpose, a reference soil was spiked with Listeria monocytogenes cells or cell equivalents, respectively. With the purpose of evaluating optimum treatment conditions, different EMA concentrations have been tested. However, the results remained largely inconclusive. Furthermore,...
Latest Results for Current Microbiology
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Comparison of Starvation-Induced Persister Cells with Antibiotic-Induced Persister Cells
Abstract The phenotypic heterogeneity in a large population arises because of fluctuation in microenvironments and stochastic gene expressions. In this report, we isolated two types of persistent sub-populations of Vibrio cholerae, one triggered by starvation and another by antibiotics. We characterised starvation-induced (E-cells) and antibiotic-induced (P-cell) persister cells for stress tolerance, colony morphology and toxin gene expressions. Both the sub-populations differ...
Latest Results for Current Microbiology
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The Evaluation of Imidacloprid Remediation in Soil Media by Two Bacterial Strains
Abstract Imidacloprid (C9H10ClN5O2) is used as the most recommended type of insecticide in vegetable farming worldwide. Two types of bacteria (Methylobacterium radiotolerans and Microbacterium arthrosphaerae) were isolated from a corn farming field in the Thrace region of Turkey, and then consortia of these bacteria were prepared from equal volumes of 107 CFU/ml for each bacterium type. Imidacloprid remediation studies were carried out during 18 days in soil test units. The water...
Latest Results for Current Microbiology
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