Our group has conducted two previous studies on the association between vitamin D binding protein (DBP) and renal cell carcinoma (RCC), the most common form of kidney cancer, finding strong inverse associations. We undertook the current analysis to replicate our findings in a different study population that included women and non‐smokers. We conducted a nested case‐control study in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO). Cases (n=323) were matched 1:1 to controls...
Tue Oct 29, 2019 21:53
Pancreatic cancers, both adenocarcinomas and endocrine tumors are characterized by varying levels of aberrant angiogenesis and fibrotic microenvironment. The difficulty to deliver drugs and treat the disease has been attributed in part to the vascular architecture and tissue/ECM density. Here we present longitudinal three‐dimensional intravital imaging of vascular and tumor microenvironment remodeling in spontaneous transgenic tumors (RIP1‐Tag2 insulinomas) and orthotopically injected tumors (KPC...
Tue Oct 29, 2019 18:08
An association between maternal diabetes, its medication and childhood cancer has not been previously explored in a registry‐based setting. With a case‐control design, we aimed to explore whether maternal diabetes is associated with an increased risk of childhood cancer in the offspring. Combining data from population‐based registries, we analyzed a total of 2,029 cases, i.e. persons with childhood cancer diagnosed under the age of 20 years between years 1996‐2014 and a total of 10,103 matched population...
Mon Oct 28, 2019 18:41
Neonatal herpes simplex virus (HSV) infection is a life-threatening infection with high morbidity and mortality rates. Neonatal herpes, most commonly due to HSV type 2, is a multi-system disease; however, initial pulmonary presentation is extremely unusual. We describe an infant presenting with progressive respiratory distress, which was the dominant clinical feature of HSV infection during the first days of life. Sepsis work-up and antibiotic treatment were immediately initiated; however, antiviral...
02:05
Influential nodes act as a hub for information transmission in a command and control network. The identification of influential nodes in a network of this nature is a significant and challenging task; however, it is necessary if the invulnerability of the network is to be increased. The existing k-shell method is problematic in that it features a coarse sorting granularity and does not consider the local centrality of nodes. Thus, the degree of accuracy with which the influential nodes can be identified...
02:05
Molecular probes targeting bacteria provide opportunities to target bacterial infections in vivo for both imaging and therapy. In the current study, we report the development of positron emission tomography (PET) probes for imaging of live bacterial infection based on the small molecules HLys-DOTA, a polycationic peptide synthesized as the D-isomer (RYWVAWRNRG) conjugated to 1, 4, 7, 10-tetraazacyclododecane-N′,N″,N‴,N-tetraacetic acid (DOTA) and AB1-HLys-DOTA, which includes an unnatural amino acid...
Tue Oct 29, 2019 18:05
Introduction. Many pathological conditions may benefit from cell therapy using mesenchymal stromal cells, particularly from adipose tissue (ASCs). Cells may be grafted in an environment with a remnant polymicrobial component. The aim is to investigate the behavior of ASCs when brought in contact with a large panel of bacteria. Materials and Methods. Carboxyfluorescein-labelled bacterial interaction with ASCs was followed by confocal time-lapse microscopy. Costaining with LAMP-1 was also analyzed....
Tue Oct 29, 2019 18:05
Objective. The integrity of cartilage depends on the correct synthesis of extracellular matrix (ECM) components. In case of insufficient folding of proteins in the endoplasmic reticulum (ER) of chondrocytes, ECM proteins aggregate, ER stress evolves, and the unfolded protein response (UPR) is initiated. By this mechanism, chondrocytes relieve the stress condition or initiate cell death by apoptosis. Especially persistent ER stress has emerged as a pathogenic mechanism in cartilage diseases, such...
Tue Oct 29, 2019 18:05
Trajectory planning is a prerequisite for the tracking control of a free-floating space robot. There are usually multiple planning objectives, such as the pose of the end-effector and the base attitude. In efforts to achieve these goals, joint variables are often taken as exclusive operable parameters, while the berth position is neglected. This paper provides a novel trajectory planning strategy that considers the berth position by applying screw theory and an optimization method. First, kinematic...
Tue Oct 29, 2019 18:05
This paper presents the analysis of the friction stir-processed aluminium alloy 5083-H111 gas tungsten arc-welded and friction stir-welded joints. The comparative analysis was performed on the processed and unprocessed gas tungsten arc-welded and friction stir-welded joints of similar aluminium alloy 5083-H111. The results showed a clear distinction between the friction stir processed joints and unprocessed joints. There is a good correlation observed between the microstructural results and the tensile...
Tue Oct 29, 2019 18:05
This paper proposes an adaptive fixed-time control scheme for twin-rotor systems subject to the inertia uncertainties and external disturbances. First of all, a fixed-time sliding mode surface is constructed and the corresponding controller is developed such that the fixed-time uniform ultimate boundedness of the sliding variable and tracking error could be guaranteed simultaneously, and the setting time is independent of the initial values. The adaptive update laws are developed to estimate the...
Tue Oct 29, 2019 18:05
Finite-Time Observer-Based Adaptive Control of Switched System with Unknown Backlash-Like Hysteresis
This work investigates a finite-time observer problem for a class of uncertain switched nonlinear systems in strict-feedback form, preceded by unknown hysteresis. By using a finite-time performance function, a finite-time switched state observer (FTSO) is derived using radial basis function neural networks (RBFNNs) to estimate the unmeasured states. An adaptive feedback neural network tracking control is derived based on the backstepping technique, which guarantees that all the signals of the closed-loop...
Tue Oct 29, 2019 18:05
Background. Childhood obesity is currently increasing at an alarming rate worldwide. Childhood obesity research has not been reported in urban Arusha before. This is therefore the first study to investigate the prevalence and predictors of childhood obesity in urban Arusha. Methods. A cross-sectional study was conducted involving 451 schoolchildren. Overweight was defined to range from 85th to 94th BMI percentile for age and sex while obesity was defined as above 94th BMI percentile for age and sex....
Tue Oct 29, 2019 17:05
An efficient, rapid, and fast kinetics of the metal-organic framework MOF235 was successfully prepared by microwave-assisted thermolysis strategy. Fourier transform infrared spectra (FTIR), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), N2 adsorption-desorption isotherm, and scanning electron microscopy (SEM) were used to characterize the samples. Experimental results revealed the suitability of MOF235 for use as an adsorbent for acid chrome blue K. The maximum adsorption capacity...
Tue Oct 29, 2019 17:05
At present, the enhancement of China’s comprehensive national strength, stable currency policy, and the new round of opening-up strategy layout have provided opportunities for the financial development in border areas, especially for the RMB internationalization advancement in border areas, while the lagging financial system construction in current border areas also challenges its RMB internationalization. Based on Friedman’s monetary demand theory (1970), the thesis has combined the periodical characteristics...
Tue Oct 29, 2019 15:30
In order to further improve the complexity of chaotic system, a new four-dimensional chaotic system is constructed based on Sprott B chaotic system. By analyzing the system’s phase diagrams, symmetry, equilibrium points, and Lyapunov exponents, it is found that the system can generate not only both two-wing and four-wing attractors but also the attractors with symmetrical coexistence, and the dynamic characteristics of the new system constructed are more abundant. In addition, the system is simulated...
Tue Oct 29, 2019 15:30
The residual symmetry of a negative-order Korteweg–de Vries (nKdV) equation is derived through its Lax pair. Such residual symmetry can be localized, and the original nKdV equation is extended into an enlarged system by introducing four new variables. By using Lie’s first theorem, we obtain the finite transformation for the localized residual symmetry. Furthermore, we localize the linear superposition of multiple residual symmetries and construct n-th Bäcklund transformation for this nKdV equation...
Tue Oct 29, 2019 15:05
An outbreak of African swine fever (ASF) occurred at a farm in central Namibia in March 2018. Fourteen pigs died out of a herd of 59 animals over a period of 16 days between the first and sixteenth of March 2018. The clinical signs observed included sternal recumbency, fever, weakness, pain and reluctance to move, hyperemia of the skin and anorexia, followed by death. Necropsy findings included large amounts of unclotted blood in the pleural and peritoneal cavities, diffuse carcass congestion, splenomegaly,...
Tue Oct 29, 2019 14:05
A disturbance observer-based hybrid sliding mode impedance control method is proposed in this paper, which is able to achieve robot end constant contact force-tracking control without force/torque sensors. The method requires only the values of joint torque, joint angle, and joint angular velocity, which are converted by robot servo motor signals, to implement the control. The control scheme consists of two parts: one is a disturbance observer and the other is a hybrid sliding mode impedance controller....
Tue Oct 29, 2019 14:05
Tue Oct 29, 2019 14:05
Breast cancer screening participation rates in the Edinburgh and Lothian regions...Read more on AuntMinnieEurope.comRelated Reading: Review of England screening programs seeks broad change U.K. public still trusts NHS, despite mammo screening glitch Scottish breast screening program to undergo review Report: Health screening in England falls short of targets NHS: Scottish women not invited to final breast screening
Tue Oct 29, 2019 18:22
The European Society of Radiology (ESR) has published a new book on sports...Read more on AuntMinnieEurope.comRelated Reading: ESR to host lung cancer roundtable at European Parliament ESR launches sports imaging website for IDoR 2019 ESR lauds progress of Horizon Europe initiative ESR unveils ESR Connect streaming platform ESR publishes sports imaging interviews for IDoR 2019
Tue Oct 29, 2019 18:00
The potential benefits of 3D printing and its application in cardiovascular...Read more on AuntMinnieEurope.comRelated Reading: 3D printing can bolster cardiac management Milan group uses AR, 3D printing to assist in heart surgery 3D-bioprinted model mimics real human heart properties 3D cardiac model enhances heart valve surgery 3D printing can identify device size for LAA occlusion
Tue Oct 29, 2019 09:00
Hospitals in New Zealand are rescheduling some elective surgeries and appointments...Read more on AuntMinnieEurope.comRelated Reading: Radiographers face up to uncertain future How to reduce radiographers' aches and pains Unprecedented strike action: 80% of French centers close French radiology union announces weeklong telephone strike Strike vote looms at Austria's leading hospital
Tue Oct 29, 2019 08:17
Royal Philips reported that double-digit growth in sales of ultrasound equipment...Read more on AuntMinnieEurope.comRelated Reading: Philips signs 10-year deal with Klinikum Stuttgart Philips says tariffs will take bite out of Q3 numbers Philips, PURE partner on Rwandan teleultrasound Philips to highlight ultrasound, informatics at ESC congress Philips delivers digital x-ray systems to Perth Children's Hospital
Mon Oct 28, 2019 20:34
PACS vendor Telemis reported growth in annual revenue for 2018-2019, with major...Read more on AuntMinnieEurope.comRelated Reading: Telemis unveils new software release Telemis experiences 5% bump in revenues French group chooses Telemis PACS software Telemis launches PACS upgrades Telemis launches new version of PACS software
Mon Oct 28, 2019 19:35
France's breast cancer screening strategy is at a crossroads, with urgent decisions...Read more on AuntMinnieEurope.comRelated Reading: Scotland's breast cancer screening rates keep falling French hairdressers to promote breast screening Mammography screening rates on the rise in Singapore Conebeam CT more comfortable than mammography U.K. public still trusts NHS, despite mammo screening glitch
Mon Oct 28, 2019 09:00
Objective. To explore the incidence and significance of intra- and extra-osseous edema associated with benign tumors and tumor-like diseases. Methods. Magnetic resonance imaging (MRI) data from 300 benign osseous tumors and tumor-like diseases diagnosed by pathology were retrospectively reviewed. Borderline tumors, cases associated with pathological fractures, and skull lesions were excluded from the study. Bone marrow and soft tissue edema were defined on T2WI with fat suppression on MRI in all...
Tue Oct 29, 2019 14:05
In recent times, secure communication protocols over web such as HTTPS (Hypertext Transfer Protocol Secure) are being widely used instead of plain web communication protocols like HTTP (Hypertext Transfer Protocol). HTTPS provides end-to-end encryption between the user and service. Nowadays, organizations use network firewalls and/or intrusion detection and prevention systems (IDPS) to analyze the network traffic to detect and protect against attacks and vulnerabilities. Depending on the size of...
Tue Oct 29, 2019 14:05
Through well-designed counterfeit websites, phishing induces online users to visit forged web pages to obtain their private sensitive information, e.g., account number and password. Existing antiphishing approaches are mostly based on page-related features, which require to crawl content of web pages as well as accessing third-party search engines or DNS services. This not only leads to their low efficiency in detecting phishing but also makes them rely on network environment and third-party services...
Tue Oct 29, 2019 14:05
Squamous cell papilloma (SCP) is generally a human papillomavirus (HPV) induced exophytic or endophytic proliferation on the surface of the skin, oral cavity, larynx, esophagus, cervix, vagina, and anal canal. The endophytic type SCP can cause differential diagnostic difficulties with keratoacanthoma, inverted follicular keratosis, and squamous cell carcinoma; however, these lesions are not associated with HPV infection. The authors present a female patient who noticed an extremely rapidly growing...
Tue Oct 29, 2019 12:05
Background. The number of patients receiving direct oral anticoagulants (DOACs) is increasing, however, this treatment is associated with the risk of bleeding. More than 10 percent of patients on DOACs have to interrupt their anticoagulation for an invasive procedure every year. For this reason, the correct management of DOACs in the perioperative setting is mandatory. Case Presentation. An 81-year-old male patient, with known impaired renal function, presented to our emergency department with a...
Tue Oct 29, 2019 11:05
This article presents three cases of cranial nerve palsy following shoulder surgery with general anesthesia in the beach chair position. All patients underwent preoperative ultrasound-guided interscalene nerve block. Two cases of postoperative hypoglossal and one case of combined hypoglossal and recurrent laryngeal nerve palsies (Tapia’s syndrome) were identified. Through this case series, we provide a literature review identifying postoperative cranial nerve palsies in addition to the discussion...
Tue Oct 29, 2019 11:05
Aiming at the problems of complex structures, variable loads, and fluctuation of power outputs of multienergy networks, this paper proposes an optimal allocation strategy of multienergy networks based on the double-layer nondominated sorting genetic algorithm, which can optimize the allocation of distributed generation (DG) and then improve the system economy. In this strategy, the multiobjective nondominated sorting genetic algorithm is adopted in both layers, and the second-layer optimization is...
Tue Oct 29, 2019 11:05
Metal wear debris and released ions (CoCrMo), which are widely generated in metal-on-metal bearings of hip implants, are also found in patients with metal-on-polyethylene bearings due to the mechanically assisted crevice corrosion of modular taper junctions, including head-neck and neck-stem taper interfaces. The resulting adverse reactions to metal debris and metal ions frequently lead to early arthroplasty revision surgery. National guidelines have since been published where the blood metal ion...
Tue Oct 29, 2019 11:05
Direct analysis and identification of biological tissue is significant for clinical applications. In this study, porcine liver and kidney have been analyzed using laser ablation electrospray ionization time-of-flight mass spectrometry (LAESI-TOFMS). This method showed good reproducibility for the same types of tissue and is capable of distinguishing different tissue species. The margin assessment was also performed using porcine renal tissue, and the response time was less than 6 s. Furthermore,...
Tue Oct 29, 2019 10:05
Objectives. To review the evidence of acupuncture for acute and preventive treatment of migraine for further awareness of the effect of acupuncture for migraine. Design. An overview of systematic reviews and meta-analyses (SR/MAs) for randomized controlled trials. Material and Methods. We searched PubMed, Embase, the Cochrane Library, China Knowledge Resource Integrated Database, VIP Chinese Journal Full Text Database, WANFANG Data, and China Biology Medicine disc from their establishment to May...
Tue Oct 29, 2019 10:05
With the development of computer vision technology, more and more enterprises begin to use computer vision instead of manual inspection for steel surface defect detection. However, classical image processing methods often face great difficulties when dealing with images containing noise and distortions, which leads to low computational efficiency and poor accuracy of detection. In view of the particularity of hot round steel production, a computational intelligence method is proposed in this paper....
Tue Oct 29, 2019 10:05
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