Burnout, a syndrome of emotional exhaustion, cynicism, and reduced effectiveness at work, has been linked to poor health, alcoholism, depression, and suicide in physicians. Burnout has adverse effects on patient care and the physician workforce, since burned-out physicians are more likely to report…
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Publication date: Available online 29 October 2019Source: Acta HistochemicaAuthor(s): A. Aizic, V. Raiser, I. Solar, Z. Aharon, B. Shlomi, I. KaplanAbstractIntroductionTraumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE) is a rare oral ulcerated lesion of uncertain etiology, showing eosinophil-rich granulation tissue, with occasional large atypical CD30 positive mononuclear cells. It had been suggested that it may represent an oral counterpart of cutaneous lymphomatoid papulosis, with...
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Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Swathi Chidambaram, Kevin Swong, Michael Ander, Russel P. NockelsBackgroundPseudohypoxic brain swelling (PHBS), also known as postoperative intracranial hypotension−associated venous congestion, is a rare complication after neurosurgery characterized by rapid and often severe postoperative deterioration in consciousness and distinct imaging findings on brain magnetic resonance imaging. Imaging findings associated with...
Publication date: January 2020Source: World Neurosurgery, Volume 133Author(s): Taichiro Imahori, Yusuke Okamura, Junichi Sakata, Hiroyasu Shose, Shunsuke Yamanishi, Eiji KohmuraBackgroundPseudoaneurysm after mechanical thrombectomy (MT) is rare but is one of the potential complications associated with endovascular procedures. There is limited information regarding its mechanism of formation and the potential risk of delayed bleeding.Case DescriptionAn 84-year-old woman was admitted to our institution...
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Trigeminal neuralgia (TN) is a debilitating but treatable disease. Classic TN has referable vascular compression of the trigeminal nerve, but rarely secondary sources of anatomic compression will present, including vascular malformations, aneurysms, or tumors. Understanding the etiology of the patients’ symptoms leads to targeted treatment. Three patients presented with symptoms consistent with TN: shooting, paroxysmal pains in the distribution of the trigeminal nerve. However, imaging revealed no...
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Publication date: Available online 29 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Ying-hui Chen, Yi-ling Cheng, Hui Cheng, Hao YuAbstractStatement of problemVarious components of smile esthetics have been evaluated. However, whether these components affect smile esthetics in Han Chinese celebrities, dentists, and dental students is unknown.PurposeThe purpose of this study was to evaluate the smile esthetics of celebrities, dentists, and dental students in a Han Chinese population.Material...
Publication date: Available online 29 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Volkan Sahin, Hossein Jodati, Zafer EvisAbstractStatement of problemRecent commercial extended-pour irreversible hydrocolloid impression materials (EPIHIMs) claim to maintain dimensional stability up to 120 hours. However, data regarding their mechanical properties and performance after 120 hours of storage are lacking.PurposeThe purpose of this in vitro study was to test the elastic recovery,...
Publication date: Available online 29 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Shuxin Ren, Dean Morton, Wei-Shao LinAbstractStatement of problemIntraoral scans and virtual interocclusal records (VIRs) are widely used for contemporary prosthodontic treatment of patients with partial edentulism. The accuracy of VIRs in various clinical conditions is unclear.PurposeThe purpose of this in vitro study was to investigate whether the span and location of edentulous areas affect...
Publication date: Available online 29 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Amir-Alireza Khaledi, Mitra Farzin, Marzieh Akhlaghian, Soheil Pardis, Negar MirAbstractStatement of problemDigital systems have been developed as substitutes for the traditional fabrication of wax patterns and definitive restorations, but the accuracy of these systems is unclear.PurposeThe purpose of this in vitro study was to evaluate and compare the marginal fit of metal copings fabricated from...
Publication date: Available online 29 October 2019Source: The Journal of Prosthetic DentistryAuthor(s): Yang Yang, Zhen Yang, Jianfeng Zhou, Li Chen, Jianguo TanAbstractStatement of problemAlthough different preparation designs have been proposed for onlays fabricated by computer-aided design and computer-aided manufacturing (CAD-CAM), their effect on marginal adaptation is unclear.PurposeThe purpose of this in vitro study was to investigate the effect of tooth preparation designs on the marginal...
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Condition: Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionIntervention: Drug: larotrectinib(Vitrakvi, BAY2757556)Sponsor: BayerNot yet recruiting
Condition: Squamous Cell CarcinomasIntervention: Other: solar irradiation and biopsiesSponsor: Centre Hospitalier Universitaire de NiceNot yet recruiting
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Publication date: Available online 29 October 2019Source: American Journal of OtolaryngologyAuthor(s): Danny Jandali, Sarah Shearer, Richard Byrne, Peter Papagiannopoulos, Bobby A. Tajudeen, Pete S. BatraAbstractIntroductionMultiple options exist for sellar reconstruction after endoscopic transnasal, transsphenoidal surgery (TSS) including free mucosa, fat, bone and synthetic materials. The objective of this study was to assess healing and mucosalization of the sellar face following TSS without formal...
Publication date: Available online 29 October 2019Source: American Journal of OtolaryngologyAuthor(s): Belgin Tutar, Sevgi Atar, Güler Berkiten, Onur Üstün, Tolgar Lütfi Kumral, Yavuz UyarAbstractObjectivesChronic Subjective Tinnitus is a very highly prevalent disorder worldwide. There is no definitive treatment. The aim of this study is to investigate the efficacy of transcutaneous electrical nerve stimulation (TENS) applied to the auricula for treating tinnitus using the Depression Anxiety Stress...
Publication date: Available online 28 October 2019Source: American Journal of OtolaryngologyAuthor(s): David Strum, Sunny Kim, Timothy Shim, Ashkan Monfared
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Publication date: Available online 29 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Adeline Schwein, Yannick Georg
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Publication date: January 2020Source: Magnetic Resonance Imaging, Volume 65Author(s): Jonathan M. Hanna, Danielle Temares, Fahmeed Hyder, Douglas L. Rothman, Robert K. Fulbright, Veronica L. Chiang, Daniel ComanAbstractBackground and purposeGiven increasing interest in laser interstitial thermotherapy (LITT) to treat brain tumor patients, we explored if examining multiple MRI contrasts per brain tumor patient undergoing surgery can impact predictive accuracy of survival post-LITT.Materials and methodsMRI...
Publication date: Available online 29 October 2019Source: Magnetic Resonance ImagingAuthor(s): Jamal Sakhr, Blaine A. ChronikAbstractPassive reduction of gradient coil (GC) cylinder vibration depends critically on a thorough knowledge of how all pertinent physical parameters affect the vibration response. In this paper, we employ a recently introduced linear elastodynamic Z-coil model to study how the displacement response of a whole-body GC cylinder (subject to exclusive excitation of its Z-coil...
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Nature Chemistry, Published online: 29 October 2019; doi:10.1038/s41557-019-0381-zAuthor Correction: Dopant-induced electron localization drives CO2 reduction to C2 hydrocarbons
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Loot boxes are items in video games that may be paid for with real-world money, but which contain randomised contents. There is a reliable correlation between loot box spending and problem gambling severity: the more money gamers spend on loot boxes, the more severe their problem gambling tends to be. However, it is unclear whether this link represents a case in which loot box spending causes problem gambling; a case in which the gambling-like nature of loot boxes cause problem gamblers to spend...
Background The potential of unidentified microorganisms for academic and other applications is limitless. Plants have diverse microbial communities associated with their biomes. However, few studies have focused on the microbial community structure relevant to tree bark. Methods In this report, the microbial community structure of bark from the broad-leaved tree Acer palmatum was analyzed. Both a culture-independent approach using polymerase chain reaction (PCR) amplification and next...
In 2010, the Conference of the Parties of the Convention on Biological Diversity agreed on the Strategic Plan for Biodiversity 2011–2020 in Aichi Prefecture, Japan. As this plan approaches its end, we discussed whether marine biodiversity and prediction studies were nearing the Aichi Targets during the 4th World Conference on Marine Biodiversity held in Montreal, Canada in June 2018. This article summarises the outcome of a five-day group discussion on how global marine biodiversity studies should...
Background Soil aggregate-size classes, structural units of soil, are the important factors regulating soil organic carbon (SOC) turnover. However, the processes of litter C mineralization and storage in different aggregates-size classes are poorly understood, especially in the highly alkaline soils of north China. Here, we ask how four different aggregate sizes influence rates of C release (Cr) and SOC storage (Cs) in response to three types of plant litter added to an un-grazed natural grassland....
Gene drives may be used in two ways to curtail vectored diseases. Both involve engineering the drive to spread in the vector population. One approach uses the drive to directly depress vector numbers, possibly to extinction. The other approach leaves intact the vector population but suppresses the disease agent during its interaction with the vector. This second application may use a drive engineered to carry a genetic cargo that blocks the disease agent. An advantage of the second application is...
Tree aging is a new research area and has attracted research interest in recent years. Trees show extraordinary longevity; Platycladus orientalis L. (Cupressaceae) has a lifespan of thousands of years. Ancient trees are precious historical heritage and scientific research materials. However, tree aging and tree senescence have different definitions and are poorly understood. Since leaves are the most sensitive organ of a tree, we studied the structural response of leaves to tree age. Experiments...
There is growing interest within regulatory agencies and toxicological research communities to develop, test, and apply new approaches, such as toxicogenomics, to more efficiently evaluate chemical hazards. Given the complexity of analyzing thousands of genes simultaneously, there is a need to identify reduced gene sets. Though several gene sets have been defined for toxicological applications, few of these were purposefully derived using toxicogenomics data. Here, we developed and applied a systematic...
The number of people suffering from eye fatigue induced by visual display terminal (VDT) viewing is expected to increase in the modern world. Eye dysfunction is suggested to induce a decrease in cognitive function, at least in the long term. Furthermore, considering other previous findings, it may be reasonable to think that acute or relatively short-term eye dysfunction attenuates cognitive function for not only older but also young individuals. Hence, clarification of the effect of eye fatigue...
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Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Aurélie Daumas, Jeremy Magalon, Flore Delaunay, Maxime Abellan, Cécile Philandrianos, Florence Sabatier, Brigitte Granel, Guy Magalon
Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Steven R. Cohen, Hayley Womack, Ali Ghanem
Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Patrick Tonnard, Alexis Verpaele, Marcelo Carvas
Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Shenglu Jiang, Yuping Quan, Jing Wang, Junrong Cai, Feng Lu
Publication date: Available online 28 October 2019Source: Clinics in Plastic SurgeryAuthor(s): Zhibin Yang, Ming Li, Shengyang Jin, Xinyu Zhang, Xuefeng Han, Facheng Li
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Histological examination of specimens from 22 donated elderly cadavers and 15 human fetuses revealed that the cricopharyngeus muscle (CPM) provided (1) posterior circular muscle fibers adjacent to the external aspect of the uppermost esophageal circular muscle and (2) a thin anterior sling connecting to that same muscle. Another thick lateral bundle of longitudinal muscle originated independently from a fascia covering the posterior crico‐arytenoideus muscle, extended laterally and posteriorly, and...
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Abstract We read Rannikko et al.’s article about proprotein convertase subtilisin/kexin type 9 (PCSK9) levels in patients with bacteremia [1] with great interest. In these patients PCSK9 levels were increased compared to healthy controls, which is in line with other published data and probably caused by the associated inflammatory response [2]. Interestingly, within the patient cohort, patients with lower PCSK9 levels were more likely to die at day 7, 28 and 90, which was surprising, because in...
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Publication date: 13 January 2020Source: Behavioural Brain Research, Volume 377Author(s):
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Publication date: Available online 28 October 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Toshiaki Kawakami, Yu Kawakami
Publication date: Available online 28 October 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Nikita Markov, Hans-Uwe Simon
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Abstract Background Men treated for prostate cancer experience heightened psychological distress and have an increased risk of suicide. Management of this distress and risk is crucial for quality urological care. Objective To identify risk indicators for poorer trajectories of psychological adjustment and health‐related quality of life after surgery for localised prostate cancer. Design, Setting and Participants Patients were newly diagnosed with localised prostate cancer scheduled...
Abstract Purpose To evaluate internet‐delivered cognitive behavioural therapy (iCBT) on clinical depression and/or anxiety, distress, fear of cancer recurrence and quality of life in cancer survivors. Methods Random assignation of 114 participants to iCBT or Treatment‐as‐usual (TAU). The clinician‐supervised iCBT program (iCanADAPT Early) consisted of 8‐lessons over 16‐weeks. Self‐report questionnaires occurred at baseline, mid‐point, and post‐treatment for both groups with 3‐month follow‐up...
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