Clinical Neurology and Neurosurgery
- Relationship between Cerebrovascular Atherosclerotic Stenosis and Rupture Risk of Unruptured Intracranial Aneurysm: A Single-Center Retrospective StudyPublication date: Available online 1 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Xin Feng, Peng Qi, Lijun Wang, Jun Lu, Hai Feng Wang, Junjie Wang, Shen Hu, Daming WangAbstractObjectivesCerebrovascular atherosclerotic stenosis (CAS) and intracranial aneurysm (IA) have a common underlying arterial pathology and common risk factors, but the clinical significance of CAS in IA rupture (IAR) is unclear. This study aimed to invest
- Pain at the onset of Amyotrophic Lateral Sclerosis: a cross-sectional studyPublication date: Available online 1 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Arens Taga, Paride Schito, Maria Claudia Trapasso, Lucia Zinno, Giovanni PavesiAbstractObjectiveWe evaluated ALS patients reporting pain, either generalized or localized, at disease onset and determined whether this feature defined a specific ALS phenotype.Patients and Methods: We considered all consecutive ALS patients referred to our Motor Neu
- Reliability, validity and responsiveness of the Squares Test for manual dexterity in people with Parkinson’s DiseasePublication date: Available online 1 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Fatih Söke, Berril Dönmez Colakoglu, Pembe Keskinoglu, Arzu GencAbstractObjectiveImpaired manual dexterity is one of the major disorder in people with Parkinson’s Disease (PwPD). However, there is limited research examining the measurement properties, especially the validity and responsiveness of the tools used to assess manual dexterity. The ai
- Serum lactate levels are associated with glioma malignancy gradePublication date: Available online 1 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Mariana Branco, Paulo Linhares, Bruno Carvalho, Patrícia Santos, Bruno M. Costa, Rui VazAbstractObjectiveRecent studies have suggested that high grade gliomas are associated with elevated serum lactate concentrations. The aim of the present study is to assess these findings in a sample of patients.Patients and MethodsWe reviewed the anesthetic c
- The use, misuse and abuse of paraneoplastic panels in neurological disorders. A retrospective studyPublication date: Available online 1 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Awss Zidan, Alexander Fein, Kathryn ZuchowskiAbstractObjectivesThe field of paraneoplastic neurological syndromes PNS has grown exponentially with the increased identification of associated antibodies. Testing for these antibodies is commonly done in “panels” to increase sensitivity, and these panels have become a routine test on CSF samples obt
G3: .Genes, Genomes, Genetics Mission - Online First Articles
- Genome of Spea multiplicata, a Rapidly Developing, Phenotypically Plastic, and Desert-Adapted Spadefoot ToadFrogs and toads (anurans) are widely used to study many biological processes. Yet, few anuran genomes have been sequenced, limiting research on these organisms. Here, we produce a draft genome for the Mexican spadefoot toad, Spea multiplicata, which is a member of an unsequenced anuran clade. Atypically for amphibians, spadefoots inhabit deserts. Consequently, they possess many unique adaptations, including rapid growth and development, prolonged
Society for Linguistic Anthropology
- AL8470 – SociolinguisticsInstructor/Creator: Stephanie Lindemann Institution/Campus/Department: Applied Linguistics and ESL, Georgia State University Course: AL8470 – Sociolinguistics Subject(s): Sociolinguistics Topic(s): Code Communities, Disadvantage, Discrimination, Ethnography, Gender, Language Planning, Language Variation, Language Variation and Change, Language Varieties, Linguistic Relativism;, Sociolinguistics and Education, Solidarity and Politeness, Speech
- ANT206Y5 – Culture and Communication: Introduction to Linguistic AnthropologyInstructor/Creator: Dylan Clark Institution/Campus/Department: Anthropology, University of Toronto Course: ANT206Y5 – Culture and Communication: Introduction to Linguistic Anthropology Subject(s): Introduction to Linguistic Anthropology Topic(s): Class and ethnicity, Gender, language endangerment, language in social action, language revitalization, multi-racial society, race Course Link: http://individual.utoronto.ca/rogues/ANT206201011Clark
Strahlentherapie und Onkologie
- Image-based lung functional radiotherapy planning for non-small cell lung cancerAbstract Background This simulation study assessed the feasibility and impact of incorporating additional information from lung perfusion single-photon emission computed tomography (SPECT) into intensity-modulated radiotherapy planning for the treatment of non-small cell lung cancer (NSCLC). Methods In th
- WHO grade of intracranial meningiomas differs with respect to patient’s age, location, tumor size and peritumoral edemaAbstract Purpose To analyse whether the WHO grade of intracranial meningiomas differs itself depending on patients and meningioma characteristics at diagnosis. Methods Single center retrospective study of a series of consecutive patients with primary intracranial meningiomas who underwent surgery between
- Neurological and related adverse events in immune checkpoint inhibitors: a pharmacovigilance study from the Japanese Adverse Drug Event Report databaseAbstract Introduction Immune checkpoint inhibitors (ICPI), a breakthrough immunotherapy for cancer, can cause serious neurological adverse events (AEs). We aimed to investigate the characteristics of the neurological and related AEs associated with ICPI treatment, using a large pharmacovigilance database from Japan.
- Prognostic assessment in patients with newly diagnosed small cell lung cancer brain metastases: results from a real-life cohortAbstract Purposes Brain metastases (BM) are a frequent complication in small cell lung cancer (SCLC), resulting in a reduced survival prognosis. Precise prognostic assessment is an important foundation for treatment decisions and clinical trial planning. Methods Patients with newly diagnosed
- Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201Abstract Background H3 K27M-mutant diffuse midline glioma is a fatal malignancy with no proven medical therapies. The entity predominantly occurs in children and young adults. ONC201 is a small molecule selective antagonist of dopamine receptor D2/3 (DRD2/3) with an exceptional safety profile. Following up on a durable response in the first H3 K27M-mutant diffuse midline glioma p
- Re-irradiation for children with recurrent medulloblastoma in Toronto, Canada: a 20-year experienceAbstract Purpose Children with recurrent medulloblastoma have a poor prognosis. Re-irradiation is an option for some patients, but has not been well-studied in the era of molecular characterization for pediatric medulloblastoma. Methods This was a retrospective cohort study of 14 children ag
- The protein arginine methyltransferase PRMT5 confers therapeutic resistance to mTOR inhibition in glioblastomaAbstract Introduction Clinical trials directed at mechanistic target of rapamycin (mTOR) inhibition have yielded disappointing results in glioblastoma (GBM). A major mechanism of resistance involves the activation of a salvage pathway stimulating internal ribosome entry site (IRES)-mediated protein synthesis. PRMT5 activity has been implicated in the enhancement of IRES activity.
- Receipt of brachytherapy is an independent predictor of survival in glioblastoma in the Surveillance, Epidemiology, and End Results databaseAbstract Introduction There has been a resurgence of interest in brachytherapy as a treatment for glioblastoma, with several currently ongoing clinical trials. To provide a foundation for the analysis of these trials, we analyze the Surveillance, Epidemiology, and End Results (SEER) database to determine whether receipt of brachytherapy conveys a survival benefit independent of t
- Outcome of three-fraction gamma knife radiosurgery for brain metastases according to fractionation scheme: preliminary resultsAbstract Purpose The optimal interfraction intervals for fractionated radiosurgery has yet to be established. We investigated the outcome of fractionated gamma knife radiosurgery (FGKRS) for large brain metastases (BMs) according to different interfraction intervals. Methods Between Septembe
- Evaluation of toxicity of carmustine with or without bevacizumab in patients with recurrent or progressive high grade gliomasAbstract Purpose An increased incidence in hematologic toxicity has been reported with the addition of bevacizumab to lomustine for patients with recurrent or progressive high grade gliomas (HGG). Data regarding incidence of toxicity with combination bevacizumab and carmustine is limited. The purpose of this study is to compare toxicity of single agent carmustine and carmustine p
- Ektopes Schilddrüsengewebe nach erfolgter ThyreoidektomieZusammenfassung Ektopes Schilddrüsengewebe tritt entweder als einzig nachweisbares Schilddrüsengewebe oder parallel zu einer normotopen Schilddrüse auf. Nach einer totalen Thyreoidektomie kommt es unter dem Einfluss von TSH (Thyreoidea-stimulierendes Hormon) zu einer kompensatorischen Volumenzunahme des bis dahin asymptomatischen ektopen Gewebes. Diese Vergrößerungen treten als unklare zervikale Raumforderungen auf. Vor einer O
- Evidenzbasierte VEMP-DiagnostikZusammenfassung Hintergrund Vestibulär evozierte myogene Potenziale (VEMPs) werden zunehmend zur klinischen Untersuchung der Otolithenorgane eingesetzt. Ziel der Arbeit Der Artikel vermittelt einen Überblick über anatomische, biomechanische und neurophysiologische Grundlagen einer evidenzbasierten klinisc
- Accuracy of <sup>18</sup>F-FDG PET/CT in Detection of Neck Metastases of Oral Squamous Cell Carcinoma in Patients Without Large Palpable Lymph NodesPublication date: Available online 2 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Niu Lixuan, Zheng Dong, Wang Dian Can, Zhang Jianyun, Fei Jun, Guo ChuanbinAbstractObjectivesTo measure the efficacy of positron emission tomography/computed tomography (PET/CT) in the diagnosis of neck metastases of oral squamous cell carcinoma (OSCC) in patients without enlarged lymph nodes and to determine the thres
- Corrigendum to Letter regarding Salma et al. “Vital signs changes during different dental procedures: A prospective longitudinal crossover clinical trial” [Oral Surg Oral Med Oral Pathol Oral Radiol 128 (2019): 96]Publication date: Available online 1 October 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Craig S. Miller
bioRxiv Subject Collection: Evolutionary Biology
- Transgenerational dispersal plasticity and its fitness consequences are under genetic control [NEW RESULTS]Phenotypic plasticity, the ability of one genotype to produce different phenotypes in different environments, plays a central role in species response to environmental changes. Transgenerational plasticity (TGP) allows the transmission of this environmentally-induced phenotypic variation across generations, and can influence adaptation. To date, the genetic control of TGP, its long-term stability, and its potential costs remain largely unknown, m
- Massive haplotypes underlie ecotypic differentiation in sunflowers [NEW RESULTS]Species often include multiple ecotypes that are adapted to different environments. But how do ecotypes arise, and how are their distinctive combinations of adaptive alleles maintained despite hybridization with non-adapted populations? Re-sequencing of 1506 wild sunflowers from three species identified 37 large (1-100 Mbp), non-recombining haplotype blocks associated with numerous ecologically relevant traits, and soil and climate characteristic
- Sex-specific phenotypic effects and evolutionary history of an ancient deletion polymorphism of the human growth hormone receptor [NEW RESULTS]The deletion of the third exon of the growth hormone receptor (GHRd3) is one of the most common genomic structural variants in the human genome. This deletion has been linked to response to growth hormone, placenta size, birth weight, growth after birth, time of menarche, adult height, and longevity. However, its evolutionary history and the exact mechanisms through which it affects phenotypes remain unresolved. While the analysis of thousands of
- When do individuals maximize their inclusive fitness? [NEW RESULTS]Adaptation is often described in behavioral ecology as individuals maximizing their inclusive fitness. Under what conditions does this hold and how does this relate to the gene-centered perspective of adaptation? We unify and extend the literature on these questions to class-structured populations. We demonstrate that the maximization (in the best-response sense) of class-specific inclusive fitness obtains in uninvadable population states (meanin
- Protective effects of betaine on diabetic induced disruption of the male mice blood-testis barrier by regulating oxidative stress-mediated p38 MAPK pathwaysPublication date: December 2019Source: Biomedicine & Pharmacotherapy, Volume 120Author(s): Ya-Ping Jiang, Jia-Mei Yang, Rui-Juan Ye, Ning Liu, Wen-Jin Zhang, Lin Ma, Ping Zheng, Jian-Guo Niu, Ping Liu, Jian-Qiang YuAbstractBackgroundBlood-testis barrier (BTB) impairments is one of the major secondary complications of diabetes. Betaine (BET) is the important active ingredients isolated from Lycium barbarum, which exhibits numerous pharmacological
PeerJ Computer Science
- Expression of leptin and leptin receptors in colorectal cancer—an immunohistochemical studyObesity is demonstrated to be a risk factor in the development of cancers of various organs, such as colon, prostate, pancreas and so on. Leptine (LEP) is the most renowned of the adipokines. As a hormone, it mediates its effect through leptin receptor (LEPR), which is widely expressed in various tissues including colon mucosa. In this study, we have investigated the degree of expression of LEP and LEPR in colorectal cancer (CRC). We collected 44
- Examining the influence of picture format on children’s naming responsesDigital photography has facilitated the use of more ecological stimuli than line drawings as experimental stimuli. However, there is lack of evidence regarding the effect of the picture format on children’s naming agreement. The present work investigated whether the format of presentation of the pictures (line drawing or photograph) affects naming task performance in children. Two naming task experiments are reported using 106 concepts depicted b
- Tandem mass tag-based quantitative proteomic analysis of lycorine treatment in highly pathogenic avian influenza H5N1 virus infectionHighly pathogenic H5N1 influenza viruses (HPAIV) cause rapid systemic illness and death in susceptible animals, leading to a disease with high morbidity and mortality rates. Although vaccines and drugs are the best solution to prevent this threat, a more effective treatment for H5 strains of influenza has yet to be developed. Therefore, the development of therapeutics/drugs that combat H5N1 influenza virus infection is becoming increasingly impor
- Variation of 13C and 15N enrichments in different plant components of labeled winter wheat (Triticum aestivum L.)Information on the homogeneity and distribution of 13carbon (13C) and nitrogen (15N) labeling in winter wheat (Triticum aestivum L.) is limited. We conducted a dual labeling experiment to evaluate the variability of 13C and 15N enrichment in aboveground parts of labeled winter wheat plants. Labeling with 13C and 15N was performed on non-nitrogen fertilized (−N) and nitrogen fertilized (+N, 250 kg N ha−1) plants at the elongation and grain filling
- Whole genome sequencing of a novel, dichloromethane-fermenting Peptococcaceae from an enrichment cultureBacteria capable of dechlorinating the toxic environmental contaminant dichloromethane (DCM, CH2Cl2) are of great interest for potential bioremediation applications. A novel, strictly anaerobic, DCM-fermenting bacterium, “DCMF”, was enriched from organochlorine-contaminated groundwater near Botany Bay, Australia. The enrichment culture was maintained in minimal, mineral salt medium amended with dichloromethane as the sole energy source. PacBio wh
- Cooperation in bottlenose dolphins: bidirectional coordination in a rope-pulling taskIn comparison with terrestrial animals, such as primates, there is limited empirical evidence for cooperative behavior in marine mammals under experimental conditions. In this study, we used a cooperative rope-pulling task to investigate how bottlenose dolphins (Tursiops truncatus) coordinate their behavior with a partner. Dolphins successfully learned and were able to perform the task, even when one subject started after the other. In the no-del
- Structural analysis of urinary light chains and proteomic analysis of hyaline tubular casts in light chain associated kidney disordersBackground Monoclonal overproduction of kappa and/or lambda light chains might result in renal light chain deposition disease. Light chain associated cast nephropathy and renal AL-amyloidosis represent two further pathologies going along with monoclonal gammopathy of renal significance and multiple myeloma. While cast nephropathy often manifests with acute kidney injury, AL-amyloidosis is rather accompanied with chronic kidney di
- Increased expression of RUNX1 in clear cell renal cell carcinoma predicts poor prognosisBackground Runt-related transcription factor 1 (RUNX1) was previously reported to play a dual role in promoting or suppressing tumorigenesis in various malignancies. A public dataset from The Cancer Genome Atlas (TCGA) was used to evaluate the role of RUNX1 in clear cell renal cell carcinoma (ccRCC). Methods The Wilcoxon signed-rank test was used to compare the expre
- Clinical implications of aberrant neurovascular structures coursing through the submandibular glandBackground Variation within the submandibular triangle, including variant paths of facial neurovasculature, could increase risk of neurovascular derangement during submandibular gland (SMG) dysfunction, enlargement, interventions, or removal. Methods Frequency of anatomical variants enveloped within or piercing the SMG, including facial artery, vein, or branches of C
- Trans-oral robotic surgery versus coblation tongue base reduction for obstructive sleep apnea syndromeObjectives To compare the efficacy of trans-oral robotic surgery (TORS) with that of coblation assisted tongue base reduction surgery in patients with obstructive sleep apnea syndrome (OSAS). Subjects and Methods The medical charts were retrospectively reviewed for all OSAS patients admitted to one institution for surgical intervention between 2012 and 2017. We analy
- Extensive plastome reduction and loss of photosynthesis genes in Diphelypaea coccinea, a holoparasitic plant of the family OrobanchaceaeBackground Parasitic plants have the ability to obtain nutrients from their hosts and are less dependent on their own photosynthesis or completely lose this capacity. The reduction in plastid genome size and gene content in parasitic plants predominantly results from loss of photosynthetic genes. Plants from the family Orobanchaceae are used as models for studying plastid genome evolution in the transition from an autotrophic to
Case Reports in Oncology
- Vancomycin Induced Thrombocytopenia – Protracted Course in a Hemodialysis PatientVancomycin induced thrombocytopenia (VIT) is an uncommon side effect of vancomycin which can manifest from mild petechiae to life-threatening bleed. Decreased renal clearance of vancomycin results in prolonged thrombocytopenia by antibody-mediated platelet destruction in the presence of vancomycin. Improvement in thrombocytopenia is achieved with the elimination of vancomycin. We describe a patient with end stage renal disease who experienced a p
- Factors associated with sentinel lymph node status and prognostic role of completion lymph node dissection for thick melanomaPublication date: Available online 2 October 2019Source: European Journal of Surgical OncologyAuthor(s): Aram Boada, Antonio Tejera-Vaquerizo, Simone Ribero, Susana Puig, David Moreno-Ramírez, Pietro Quaglino, Simona Osella-Abate, Paola Cassoni, Josep Malvehy, Cristina Carrera, Ramon Pigem, Alicia Barreiro-Capurro, Celia Requena, Victor Traves, Esperanza Manrique-Silva, Almudena Fernández-Orland, Lara Ferrandiz, Oihane García-Senosiain, María T.
- Re-resection for incidentally detected gallbladder cancer: Weighing in on the optionsPublication date: Available online 1 October 2019Source: European Journal of Surgical OncologyAuthor(s): William Torén, Daniel Ansari, Kjetil Søreide, Roland Andersson
- Jarcho–Levin Syndrome and Concomitant Carotid Glomus Tumor: First Reported CasePublication date: December 2019Source: World Neurosurgery, Volume 132Author(s): Serap Satis, Mustafa Tuna, Nur Alparslan, Osman DereBackgroundJarcho-Levin syndrome (JLS) is a rare congenital disorder characterized by different clinical and radiologic findings. The disease was first reported by Jarcho and Levin in 1938, and it was described as the presence of various malformations or abnormal fusion in the thoracic vertebrae and ribs, short trunk,
Head and Neck
- A minimally invasive endoscopic transnasal retropterygoid approach to the upper parapharyngeal space: anatomic studies and surgical implications.A minimally invasive endoscopic transnasal retropterygoid approach to the upper parapharyngeal space: anatomic studies and surgical implications. Int Forum Allergy Rhinol. 2019 Oct 01;: Authors: Liu J, Sun X, Liu Q, Gu Y, Li H, Zheng C, Wang D, Fernandez-Miranda JC, Snyderman CH, Yu H Abstract BACKGROUND: Surgery remains the mainstay of treatment for lesions in the parapharyngeal space. However, gain
- Calmodulin and protein kinases A/G mediate ciliary beat response in the human nasal epithelium.Calmodulin and protein kinases A/G mediate ciliary beat response in the human nasal epithelium. Int Forum Allergy Rhinol. 2019 Oct 01;: Authors: Do BH, Nguyen TN, Baba R, Ohbuchi T, Ohkubo JI, Kitamura T, Wakasugi T, Morimoto H, Suzuki H Abstract BACKGROUND: Mucociliary clearance of the airway epithelium is an essential function for mucosal defense. We recently proposed a hypothetical mechanism of ci
- Development and validation of a preclinical model for training and assessment of cerebrospinal fluid leak repair in endoscopic skull base surgery.Development and validation of a preclinical model for training and assessment of cerebrospinal fluid leak repair in endoscopic skull base surgery. Int Forum Allergy Rhinol. 2019 Oct 01;: Authors: Mattavelli D, Ferrari M, Rampinelli V, Schreiber A, Buffoli B, Deganello A, Rodella LF, Fontanella MM, Nicolai P, Doglietto F Abstract BACKGROUND: Achieving an effective endoscopic skull base reconstruction
- GALP Qualifier Scale: Initial Considerations to Classify a Voice Problem.GALP Qualifier Scale: Initial Considerations to Classify a Voice Problem. Folia Phoniatr Logop. 2019 Oct 01;:1-9 Authors: Englert M, Mendoza V, Behlau M, De Bodt M Abstract OBJECTIVE: To propose a single qualifier scale for voice problems based on the International Classification of Functioning, Disability, and Health (ICF) that classifies a voice problem considering its multidimensionality.
- Response to salvage chemotherapy after progression on immune checkpoint inhibitors in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.Response to salvage chemotherapy after progression on immune checkpoint inhibitors in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. Eur J Cancer. 2019 Sep 28;121:123-129 Authors: Saleh K, Daste A, Martin N, Pons-Tostivint E, Auperin A, Herrera-Gomez RG, Baste-Rotllan N, Bidault F, Guigay J, Le Tourneau C, Saada-Bouzid E, Even C Abstract BACKGROUND: Immune che
- LIN28: A cancer stem cell promoter for immunotherapy in head and neck squamous cell carcinoma.LIN28: A cancer stem cell promoter for immunotherapy in head and neck squamous cell carcinoma. Oral Oncol. 2019 Sep 28;98:92-95 Authors: Li M, Chen H, Wu T Abstract Lin28, a highly conserved RNA-binding protein, plays an important role in differentiation, metabolism, proliferation, pluripotency, and tumourigenicity. Lin28 overexpression promotes tumour-cell proliferation and metastasis in various hum
- Setting the stage: Contemporary staging of non-melanomatous skin cancer and implementation of the new American Joint Committee on cancer eighth edition staging manual.Setting the stage: Contemporary staging of non-melanomatous skin cancer and implementation of the new American Joint Committee on cancer eighth edition staging manual. Oral Oncol. 2019 Sep 28;98:102-108 Authors: Casswell G, Cavanagh K, Ravi Kumar AS, Giddings C, McDowell L Abstract Non-melanomatous skin cancer (NMSC) generally refers to basal cell and squamous cell carcinoma of the skin. The majority
- Comparison of the Performance of Mask Ventilation Between Face Masks With and Without Air Cushion.Comparison of the Performance of Mask Ventilation Between Face Masks With and Without Air Cushion. J Oral Maxillofac Surg. 2019 Sep 06;: Authors: Tsukamoto M, Taura S, Hitosugi T, Yokoyama T Abstract PURPOSE: Mask ventilation is a basic technique for induction of anesthesia. In head and neck surgery, we have encountered difficulty in ventilation owing to facial deformities. Recently, a new type of fa
- Omethoate induces pharyngeal cancer cell proliferation and G1/S cell cycle progression by activation of Akt/GSK-3β/cyclin D1 signaling pathway.Omethoate induces pharyngeal cancer cell proliferation and G1/S cell cycle progression by activation of Akt/GSK-3β/cyclin D1 signaling pathway. Toxicology. 2019 Sep 28;:152298 Authors: Huo D, Jiang S, Qin Z, Feng Y, Yang R, Lv L, Li Y Abstract Omethoate is a broad category of organophosphorous pesticides (OPs) and has toxic effects on human health under long-term, low-dose exposure. However, the role
- Zınc Fınger Proteın 703 ıs an ımportant player ın head and neck cancer.Zınc Fınger Proteın 703 ıs an ımportant player ın head and neck cancer. Clin Otolaryngol. 2019 Oct 01;: Authors: Orhan C, Bakır B, Dalay N, Buyru N Abstract OBJECTIVES: Despite advances in treatment, head and neck squamous cell carcinoma (HNSCC) remains difficult to treat and the overall survival rate has only modestly improved over the past years. Therefore, there is a need to understand the molecul
- Emerging Roles of Clinical Ethicists.Emerging Roles of Clinical Ethicists. J Clin Ethics. 2019;30(3):262-269 Authors: Farroni JS, Tumilty E, Mukherjee D, McCammon S, Chooljian DM, Eves MM Abstract Debates regarding clinical ethicists' scope of practice are not novel and will continue to evolve. Rapid changes in healthcare delivery, outcomes, and expectations have necessitated flexibility in clinical ethicists' roles whereby hospital-bas
- Immune checkpoint inhibitors for head and neck squamous cell carcinoma: Current landscape and future directions.Immune checkpoint inhibitors for head and neck squamous cell carcinoma: Current landscape and future directions. Head Neck. 2019 Oct;41 Suppl 1:4-18 Authors: Kao HF, Lou PJ Abstract BACKGROUND: Immune checkpoint inhibitors (ICIs) can reinvigorate T cells and activate the immune system to eliminate cancer cells. Head and neck squamous cell carcinoma (HNSCC) is a malignancy with a poor prognosis. The r
- Preface for the special issue of "Immunotherapy for head and neck cancers: Current landscapes, emerging biomarkers, and future directions".Preface for the special issue of "Immunotherapy for head and neck cancers: Current landscapes, emerging biomarkers, and future directions". Head Neck. 2019 Oct;41 Suppl 1:3 Authors: Lou PJ PMID: 31573751 [PubMed - in process]
- Novel immune-modulating drugs for advanced head and neck cancer.Novel immune-modulating drugs for advanced head and neck cancer. Head Neck. 2019 Oct;41 Suppl 1:46-56 Authors: Chen TH, Chang PM, Yang MH Abstract BACKGROUND: Recently, two anti-PD-1 immune checkpoint inhibitors, pembrolizumab and nivolumab, have been approved by the US Food and Drug Administration for patients who fail on platinum-based chemotherapy. However, overall response and progression-free su
- Review of emerging biomarkers in head and neck squamous cell carcinoma in the era of immunotherapy and targeted therapy.Review of emerging biomarkers in head and neck squamous cell carcinoma in the era of immunotherapy and targeted therapy. Head Neck. 2019 Oct;41 Suppl 1:19-45 Authors: Hsieh JC, Wang HM, Wu MH, Chang KP, Chang PH, Liao CT, Liau CT Abstract BACKGROUND: Biomarkers in head and neck squamous cell carcinoma (HNSCC) emerge rapidly in recent years, especially for new targeted therapies and immunotherapies.
- Comparative Analyses of Tumour Volume Doubling Times for Periocular and Non-periocular Head and Neck Basal Cell Carcinomas.Comparative Analyses of Tumour Volume Doubling Times for Periocular and Non-periocular Head and Neck Basal Cell Carcinomas. Acta Derm Venereol. 2019 Sep 25;: Authors: Khoo ABS, Goon PKY, Sudhoff H, Goon PKC Abstract Basal cell carcinomas are the commonest solid malignancy in humans and thought to grow faster in the periocular region. We measured growth rates between periocular and non-periocular nodu
- Automatic classification of cochlear implant electrode cavity positioning.Automatic classification of cochlear implant electrode cavity positioning. Med Image Comput Comput Assist Interv. 2018 Sep;11073:47-54 Authors: Noble JH, Labadie RF, Dawant BM Abstract Cochlear Implants (CIs) restore hearing using an electrode array that is surgically implanted into the intra-cochlear cavities. Research has indicated that each electrode can lie in one of several cavities and that loc
- Automatic Tumor Segmentation With a Convolutional Neural Network in Multiparametric MRI: Influence of Distortion Correction.Automatic Tumor Segmentation With a Convolutional Neural Network in Multiparametric MRI: Influence of Distortion Correction. Tomography. 2019 Sep;5(3):292-299 Authors: Bielak L, Wiedenmann N, Henrik Nicolay N, Lottner T, Fischer J, Bunea H, Grosu AL, Bock M Abstract Precise tumor segmentation is a crucial task in radiation therapy planning. Convolutional neural networks (CNNs) are among the highest s
- Oral Care Protocol for Chemotherapy- and Radiation Therapy-Induced Oral Complications in Cancer Patients: Study Protocol.Oral Care Protocol for Chemotherapy- and Radiation Therapy-Induced Oral Complications in Cancer Patients: Study Protocol. Asia Pac J Oncol Nurs. 2019 Oct-Dec;6(4):417-423 Authors: Pai RR, Ongole R, Banerjee S, Prasad K, George LS, George A, Nayak BS Abstract Objective: The purpose of this study is to describe a randomized control trial protocol that assesses the effectiveness of an oral care protocol
- Physical Symptoms, Unmet Needs, and Quality of Life in Thai Cancer Survivors after the Completion of Primary Treatment.Physical Symptoms, Unmet Needs, and Quality of Life in Thai Cancer Survivors after the Completion of Primary Treatment. Asia Pac J Oncol Nurs. 2019 Oct-Dec;6(4):363-371 Authors: Pongthavornkamol K, Lekdamrongkul P, Pinsuntorn P, Molassiotis A Abstract Objectives: This study investigated physical symptoms, unmet supportive care needs, and quality of life (QoL) perception among different types of Thai
- The Highly Pure Neem Leaf Extract, SCNE, Inhibits Tumorigenesis in Oral Squamous Cell Carcinoma via Disruption of Pro-tumor Inflammatory Cytokines and Cell Signaling.The Highly Pure Neem Leaf Extract, SCNE, Inhibits Tumorigenesis in Oral Squamous Cell Carcinoma via Disruption of Pro-tumor Inflammatory Cytokines and Cell Signaling. Front Oncol. 2019;9:890 Authors: Morris J, Gonzales CB, De La Chapa JJ, Cabang AB, Fountzilas C, Patel M, Orozco S, Wargovich MJ Abstract Oral squamous cell carcinoma (OSCC) is a deadly disease that comprises 60% of all head and neck sq
- Restricted Speech Recognition in Noise and Quality of Life of Hearing-Impaired Children and Adolescents With Cochlear Implants - Need for Studies Addressing This Topic With Valid Pediatric Quality of Life Instruments.Restricted Speech Recognition in Noise and Quality of Life of Hearing-Impaired Children and Adolescents With Cochlear Implants - Need for Studies Addressing This Topic With Valid Pediatric Quality of Life Instruments. Front Psychol. 2019;10:2085 Authors: Huber M, Havas C Abstract Cochlear implants (CI) support the development of oral language in hearing-impaired children. However, even with CI, speec
- Systematically Analyzing the Pathogenic Variations for Acute Intermittent Porphyria.Systematically Analyzing the Pathogenic Variations for Acute Intermittent Porphyria. Front Pharmacol. 2019;10:1018 Authors: Fu Y, Jia J, Yue L, Yang R, Guo Y, Ni X, Shi T Abstract The rare autosomal dominant disorder acute intermittent porphyria (AIP) is caused by the deficient activity of hydroxymethylbilane synthase (HMBS). The symptoms of AIP are acute neurovisceral attacks which are induced by th
- Lung Adenocarcinoma with Cheek Dysesthesia as an Initial Symptom: A Case Report and Literature Review.Lung Adenocarcinoma with Cheek Dysesthesia as an Initial Symptom: A Case Report and Literature Review. Case Rep Oncol. 2019 May-Aug;12(2):650-656 Authors: Bandoh N, Ichikawa H, Asahi A, Kono M, Harabuchi S, Sato R, Uemura A, Goto T, Yamaguchi T, Kato Y, Furukawa H, Takei H, Harabuchi Y Abstract Metastasis from lung carcinoma to the sphenoid bone is rare. Patients with symptoms related to sphenoid bon
- Comparative evaluation of forced air warming and infusion of amino acid-enriched solution on intraoperative hypothermia in patients undergoing head and neck cancer surgeries: A prospective randomised study.Comparative evaluation of forced air warming and infusion of amino acid-enriched solution on intraoperative hypothermia in patients undergoing head and neck cancer surgeries: A prospective randomised study. Saudi J Anaesth. 2019 Oct-Dec;13(4):318-324 Authors: Gupta N, Bharti SJ, Kumar V, Garg R, Mishra S, Bhatnagar S Abstract Background: Inadvertent core hypothermia is a common occurrence during gene
- A study on the epidemiology of tinnitus in the United Kingdom.A study on the epidemiology of tinnitus in the United Kingdom. Clin Epidemiol. 2019;11:855-871 Authors: Stohler NA, Reinau D, Jick SS, Bodmer D, Meier CR Abstract Purpose: Subjective tinnitus is a common symptom with potentially negative impact on quality of life. More research is required to gain a deeper understanding of the disease and its clinical presentation. To estimate the incidence of tinnit
- GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer.GADD45a Mediated Cell Cycle Inhibition Is Regulated By P53 In Bladder Cancer. Onco Targets Ther. 2019;12:7591-7599 Authors: Han N, Yuan F, Xian P, Liu N, Liu J, Zhang H, Zhang H, Yao K, Yuan G Abstract Background: Bladder cancer (BC) is one of the most prevalent malignancies of the genitourinary system, yet the underlying mechanism of BC progression still remains unclear. Growth arrest and DNA damage
- CD44-Targeted Magnetic Nanoparticles Kill Head And Neck Squamous Cell Carcinoma Stem Cells In An Alternating Magnetic Field.CD44-Targeted Magnetic Nanoparticles Kill Head And Neck Squamous Cell Carcinoma Stem Cells In An Alternating Magnetic Field. Int J Nanomedicine. 2019;14:7549-7560 Authors: Su Z, Liu D, Chen L, Zhang J, Ru L, Chen Z, Gao Z, Wang X Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignant tumor in the world. Studies in recent years have demonstrated that canc
- Modified equipment for facilitating the transoral vestibular approach to endoscopic thyroidectomy.Modified equipment for facilitating the transoral vestibular approach to endoscopic thyroidectomy. J Minim Access Surg. 2019 Oct 01;: Authors: Bamroong P, Kasemsiri P, Thongrong C, Mahawerawat K, Tongwiset S, Rachain A, Khaengraeng S Abstract Objectives: The objectives of the study were to investigate the improvement in operation time for thyroid surgery gained using a modified endobag and suture and
- Animal models used to study direct peripheral nerve repair: a systematic review.Animal models used to study direct peripheral nerve repair: a systematic review. Neural Regen Res. 2020 Mar;15(3):491-502 Authors: Vela FJ, Martínez-Chacón G, Ballestín A, Campos JL, Sánchez-Margallo FM, Abellán E Abstract Objective: Peripheral nerve repair is required after traumatic injury. This common condition represents a major public health problem worldwide. Recovery after nerve repair depends
- Palliative care knowledge, information sources, and beliefs: Results of a national survey of adults in the USA.Palliative care knowledge, information sources, and beliefs: Results of a national survey of adults in the USA. Palliat Support Care. 2019 Oct 01;:1-8 Authors: Adjei Boakye E, Mohammed KA, Osazuwa-Peters N, Lee MJ, Slomer L, Emuze D, Jenkins WD Abstract OBJECTIVE: Despite its established benefits, palliative care (PC) is not well known among patients and family/caregivers. From a nationally represent
- Patients with head and neck cancer: Are they frailer than patients with other solid malignancies?Patients with head and neck cancer: Are they frailer than patients with other solid malignancies? Eur J Cancer Care (Engl). 2019 Sep 30;:e13170 Authors: Bras L, Driessen DAJJ, de Vries J, Festen S, van der Laan BFAM, van Leeuwen BL, de Bock GH, Halmos GB Abstract OBJECTIVE: We aimed to compare frailty status between patients with head and neck cancer (HNC) and other solid malignancies. METHO
- Probe-based fluorescence dosimetry of an antibody-dye conjugate to identify head and neck cancer as a first step to fluorescence-guided tissue preselection for pathological assessment.Probe-based fluorescence dosimetry of an antibody-dye conjugate to identify head and neck cancer as a first step to fluorescence-guided tissue preselection for pathological assessment. Head Neck. 2019 Oct 01;: Authors: Nishio N, van Keulen S, van den Berg NS, Lu G, LaRochelle EP, Davis SC, Martin BA, Fakurnejad S, Zhou Q, Birkeland AC, Kaplan MJ, Divi V, Colevas AD, Pogue BW, Rosenthal EL Abstract BA
- Effects of oral and oropharyngeal cancer on speech intelligibility using acoustic analysis: Systematic review.Effects of oral and oropharyngeal cancer on speech intelligibility using acoustic analysis: Systematic review. Head Neck. 2019 Sep 30;: Authors: Balaguer M, Pommée T, Farinas J, Pinquier J, Woisard V, Speyer R Abstract BACKGROUND: The development of automatic tools based on acoustic analysis allows to overcome the limitations of perceptual assessment for patients with head and neck cancer. The aim of
- Upregulated NPM1 is an independent biomarker to predict progression and prognosis of oral squamous cell carcinomas in Taiwan.Upregulated NPM1 is an independent biomarker to predict progression and prognosis of oral squamous cell carcinomas in Taiwan. Head Neck. 2019 Oct 01;: Authors: Peng HH, Ko HH, Chi NC, Wang YP, Lee HC, Pan PY, Kuo MY, Cheng SJ Abstract BACKGROUND: Nucleophosmin/nucleoplasmin family 1 (NPM1) has broad physiological functions, such as DNA replication, transcription, ribosome biogenesis, and centrosome r
- Rapid head and neck tissue identification in thyroid and parathyroid surgery using optical coherence tomography.Rapid head and neck tissue identification in thyroid and parathyroid surgery using optical coherence tomography. Head Neck. 2019 Oct 01;: Authors: Yang N, Boudoux C, De Montigny E, Maniakas A, Gologan O, Madore WJ, Khullar S, Guertin L, Christopoulos A, Bissada E, Ayad T Abstract BACKGROUND: Optical coherence tomography (OCT) is a noninvasive imaging modality that may reproduce the microarchitecture
- Nutritional experiences in head and neck cancer patients.Nutritional experiences in head and neck cancer patients. Eur J Cancer Care (Engl). 2019 Sep 30;:e13168 Authors: Sandmael JA, Sand K, Bye A, Solheim TS, Oldervoll L, Helvik AS Abstract OBJECTIVE: Extensive research has documented the negative nutritional impact of head neck cancer (HNC) treatment, but few studies have addressed the patients' experiences. The purpose of this study was to describe how
- Recent developments and highlights in allergic rhinitis.Recent developments and highlights in allergic rhinitis. Allergy. 2019 Sep 30;: Authors: Meng Y, Wang C, Zhang L Abstract Allergic rhinitis (AR) is a disease with high prevalence all over the world and therefore needs to be thoroughly investigated and treated accordingly. The mechanisms underlying the pathology and treatment of AR have been widely studied, but many aspects remain unclear and warrant
- Nicotinamide N-methyltransferase in nonmelanoma skin cancers.Nicotinamide N-methyltransferase in nonmelanoma skin cancers. Eur J Clin Invest. 2019 Sep 30;:e13175 Authors: Pompei V, Salvolini E, Rubini C, Lucarini G, Molinelli E, Brisigotti V, Pozzi V, Sartini D, Campanati A, Offidani A, Emanuelli M Abstract BACKGROUND: Squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) represent the most common forms of nonmelanoma skin cancers (NMSCs). Although succ
- HPV-Related Multiphenotypic Sinonasal Carcinoma: Four Cases that Expand the Morpho-Molecular Spectrum and Include Occupational Data.HPV-Related Multiphenotypic Sinonasal Carcinoma: Four Cases that Expand the Morpho-Molecular Spectrum and Include Occupational Data. Head Neck Pathol. 2019 Sep 30;: Authors: Rupp NJ, Camenisch U, Seidl K, Rushing EJ, Anderegg N, Broglie MA, Holzmann D, Morand GB Abstract HPV-related multiphenotypic sinonasal carcinoma (HMSC) is a recently described distinct tumor entity of the sinonasal tract associa
- The vibrating ossicular prosthesis in children and adolescents: a retrospective study.The vibrating ossicular prosthesis in children and adolescents: a retrospective study. Eur Arch Otorhinolaryngol. 2019 Sep 30;: Authors: Lailach S, Zahnert T, Maurer J, Hempel JM, Koitschev A, Hollfelder D, Frenzel H, Wollenberg B, Arndt S Abstract PURPOSE: The primary objective of the retrospective study was to collect speech intelligibility data on children and adolescents implanted with the vibrat
- Vertebrobasilar ischemia (VBI) related neuro-ophthalmic syndromes after routine activities involving hyperextension or rotation of the neck (hairdresser syndrome).Vertebrobasilar ischemia (VBI) related neuro-ophthalmic syndromes after routine activities involving hyperextension or rotation of the neck (hairdresser syndrome). Eye (Lond). 2019 Sep 30;: Authors: Go JA, Al Othman B, Kini A, Beaver HA, Lee AG Abstract BACKGROUND: Vertebrobasilar insufficiency (VBI) after rotation or hyperextension of the neck during otherwise routine activities is uncommon "hairdre
- Quality of life of patients with head and neck cancer after prophylactic percutaneous-gastrostomy.Quality of life of patients with head and neck cancer after prophylactic percutaneous-gastrostomy. Eur J Clin Nutr. 2019 Sep 30;: Authors: Hausmann J, Kubesch A, Goettlich CM, Rey J, Wächtershäuser A, Bojunga J, Blumenstein I Abstract BACKGROUND: HNC patients often experience weight loss during treatment. To date, there is only limited data on patient quality of life (QLQ) and subjective benefit of t
- Aberrant HER3 ligand heregulin-expressing head and neck squamous cell carcinoma is resistant to anti-EGFR antibody cetuximab, but not second-generation EGFR-TKI.Aberrant HER3 ligand heregulin-expressing head and neck squamous cell carcinoma is resistant to anti-EGFR antibody cetuximab, but not second-generation EGFR-TKI. Oncogenesis. 2019 Sep 30;8(10):54 Authors: Yonesaka K, Tanaka K, Kitano M, Kawakami H, Hayashi H, Takeda M, Sakai K, Nishio K, Doi K, Nakagawa K Abstract The anti-epidermal growth factor receptor (EGFR) antibody cetuximab is standard therapy
- [Giant cell reparative granuloma of the temporal bone: A case report].[Giant cell reparative granuloma of the temporal bone: A case report]. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Aug 28;44(8):935-940 Authors: Song J, Mei L, Cai X Abstract Giant cell reparative granuloma (GCRG) is a type of non-neoplastic lesion that can be rarely found in clinical practices. Due to the lack of specificity in symptoms, signs and auxiliary examinations, it is likely to be misdiagnose
- Intraoperative cone-beam CT spatial priors for diffuse optical fluorescence tomography.Intraoperative cone-beam CT spatial priors for diffuse optical fluorescence tomography. Phys Med Biol. 2019 Sep 30;: Authors: Daly MJ, Chan H, Muhanna N, Akens MK, Wilson BC, Irish JC, Jaffray DA Abstract A hybrid system for intraoperative cone-beam CT (CBCT) imaging and continuous-wave fluorescence tomography (FT) has been developed using an image-guidance framework. Intraoperative CBCT images with
- β-Catenin is required for radial cell patterning and identity in the developing mouse cochlea.β-Catenin is required for radial cell patterning and identity in the developing mouse cochlea. Proc Natl Acad Sci U S A. 2019 Sep 30;: Authors: Jansson L, Ebeid M, Shen JW, Mokhtari TE, Quiruz LA, Ornitz DM, Huh SH, Cheng AG Abstract Development of multicellular organs requires the coordination of cell differentiation and patterning. Critical for sound detection, the mammalian organ of Corti contains
- Diameter of External Carotid Arteries in Patients With Mandibular Osteoradionecrosis.Diameter of External Carotid Arteries in Patients With Mandibular Osteoradionecrosis. Anticancer Res. 2019 Oct;39(10):5689-5693 Authors: Ishibashi N, Maebayashi T, Aizawa T, Sakaguchi M, Okada M Abstract BACKGROUND/AIM: To evaluate the association between osteoradionecrosis (ORN) of the mandible and stenosis of the external carotid artery after radiation therapy (RT) for head and neck cancer.
- Cyclo-oxygenase-2 Expression Is Associated With Lymph Node Metastasis in Oropharyngeal Squamous Cell Carcinoma Under the New TNM Classification.Cyclo-oxygenase-2 Expression Is Associated With Lymph Node Metastasis in Oropharyngeal Squamous Cell Carcinoma Under the New TNM Classification. Anticancer Res. 2019 Oct;39(10):5623-5630 Authors: Sekimizu M, Ozawa H, Saito S, Ikari Y, Nakahara N, Nakamura S, Yoshihama K, Ito F, Watanabe Y, Imanishi Y, Kameyama K, Ogawa K Abstract BACKGROUND: This study aimed to investigate p16 and COX2 expression in
- Immunohistochemical Analysis of Transcription Factors and Markers of Epithelial-Mesenchymal Transition (EMT) in Human Tumors.Immunohistochemical Analysis of Transcription Factors and Markers of Epithelial-Mesenchymal Transition (EMT) in Human Tumors. Anticancer Res. 2019 Oct;39(10):5437-5448 Authors: Ghulam J, Stuerken C, Wicklein D, Pries R, Wollenberg B, Schumacher U Abstract BACKGROUND/AIM: Epithelial-mesenchymal transition (EMT) is a key multi-step process which enables cancer cells to detach from the epithelial primar
- Performance Characteristics of Photoacoustic Imaging Probes with Varying Frequencies and Light Delivery Schemes.Performance Characteristics of Photoacoustic Imaging Probes with Varying Frequencies and Light Delivery Schemes. Ultrason Imaging. 2019 Sep 30;:161734619879043 Authors: Rich LJ, Chamberlain SR, Falcone DR, Bruce R, Heinmiller A, Xia J, Seshadri M Abstract Photoacoustic imaging (PAI) is an emerging biomedical imaging technique that utilizes a combination of light and ultrasound to detect photoabsorber
- The Efficiency of Routine Histopathological Examination for Bilateral Nasal Polyposis.The Efficiency of Routine Histopathological Examination for Bilateral Nasal Polyposis. Ear Nose Throat J. 2019 Sep 30;:145561319872728 Authors: Safadi A, Carmel-Neiderman NN, Toledano R, Ungar OJ, Mokh FA, Wengier A, Fliss DM, Yafit D Abstract The necessity to routinely carry out histopathologic examinations of surgically removed polyps in patients with chronic rhinosinusitis with bilateral nasal pol
- Investigating Patient Preferences in Medical Student Attire in the Outpatient Otolaryngology Setting.Investigating Patient Preferences in Medical Student Attire in the Outpatient Otolaryngology Setting. Ear Nose Throat J. 2019 Sep 30;:145561319871911 Authors: Sax L, Wong K, Shetty KR, Devaiah AK, Levi J, Grillone GA Abstract BACKGROUND: The authors sought to investigate patient preferences on physician and medical student attire in the outpatient otolaryngology setting. METHODS: A prospecti
- Unusual Foreign Body in Nasal Cavity for 40 Years After Septoplasty.Unusual Foreign Body in Nasal Cavity for 40 Years After Septoplasty. Ear Nose Throat J. 2019 Sep 30;:145561319873916 Authors: Çaytemel B, Çelik M, Öztürk İE, Türel MNK PMID: 31569982 [PubMed - as supplied by publisher]
- Is Increased Time From Diagnosis to Treatment in Advanced Hypopharynx Cancer Associated With Poorer Outcomes: A Single-Centre Analysis.Is Increased Time From Diagnosis to Treatment in Advanced Hypopharynx Cancer Associated With Poorer Outcomes: A Single-Centre Analysis. Ear Nose Throat J. 2019 Sep 30;:145561319878926 Authors: Santos M, Monteiro E Abstract OBJECTIVE: To assess the potential influence of increased time from diagnosis to treatment on survival outcomes in patients with locoregionally advanced hypopharyngeal squamous cel
- Cervical Teratoma Causing Airway Obstruction in a Premature Infant.Cervical Teratoma Causing Airway Obstruction in a Premature Infant. Ear Nose Throat J. 2019 Sep 30;:145561319870479 Authors: Szymanowski AR, Bax DP, Behar P PMID: 31569980 [PubMed - as supplied by publisher]
- Amyloidosis Presenting as a Mass Abutting the Tympanic Membrane.Amyloidosis Presenting as a Mass Abutting the Tympanic Membrane. Ear Nose Throat J. 2019 Sep 30;:145561319868453 Authors: Chow K, Kaul VF, Iacob CE, Cosetti MK PMID: 31569979 [PubMed - as supplied by publisher]
- Impact of Varying Types of Nasal Septal Deviation on Nasal Airflow Pattern and Warming Function: A Computational Fluid Dynamics Analysis.Impact of Varying Types of Nasal Septal Deviation on Nasal Airflow Pattern and Warming Function: A Computational Fluid Dynamics Analysis. Ear Nose Throat J. 2019 Sep 30;:145561319872745 Authors: Li L, Zang H, Han D, London NR Abstract Nasal septal deviations (NSD) have been categorized into 7 types. The effect of these different deviations on airflow pattern and warming function has not been fully in
- Vocal Fold Hemorrhage.Vocal Fold Hemorrhage. Ear Nose Throat J. 2019 Sep 30;:145561319869914 Authors: Paknezhad H, Ramadan O, Sataloff RT PMID: 31569976 [PubMed - as supplied by publisher]
- Parotid Gland Mass as an Initial Manifestation of Oropharyngeal Carcinoma.Parotid Gland Mass as an Initial Manifestation of Oropharyngeal Carcinoma. Ear Nose Throat J. 2019 Sep 30;:145561319869609 Authors: Dowling EM, Janus JR PMID: 31569975 [PubMed - as supplied by publisher]
- Huge Trigeminal Ancient Schwannoma Involving Both Mandible and Parapharyngeal Space.Huge Trigeminal Ancient Schwannoma Involving Both Mandible and Parapharyngeal Space. Ear Nose Throat J. 2019 Sep 30;:145561319872983 Authors: Hsu PY, Lin HP, Leu YS PMID: 31569973 [PubMed - as supplied by publisher]
- Prognostic Analysis of Preoperative Inflammatory Biomarkers in Patients With Laryngeal Squamous Cell Carcinoma.Prognostic Analysis of Preoperative Inflammatory Biomarkers in Patients With Laryngeal Squamous Cell Carcinoma. Ear Nose Throat J. 2019 Sep 30;:145561319876910 Authors: Xun Y, Wang M, Sun H, Shi S, Guan B, Yu C Abstract OBJECTIVE: The purpose of this study was to demonstrate the prognostic role of inflammatory biomarkers in patients with laryngeal squamous cell carcinoma. METHODS: For this s
- Efficacy of 2 Different Intratympanic Steroid Regimen on Prevention of Cisplatin Ototoxicity: An Experimental Study.Efficacy of 2 Different Intratympanic Steroid Regimen on Prevention of Cisplatin Ototoxicity: An Experimental Study. Ear Nose Throat J. 2019 Sep 30;:145561319874311 Authors: Taş BM, Şimşek G, Azman M, Kılıç R Abstract Ototoxicity is the general name of cochlear and vestibular organ injury resulting from encountering various therapeutic agents and chemical substances. Cisplatin is commonly used in the
- Dietary Fiber, Whole Grains, and Head and Neck Cancer Prognosis: Findings from a Prospective Cohort Study.Dietary Fiber, Whole Grains, and Head and Neck Cancer Prognosis: Findings from a Prospective Cohort Study. Nutrients. 2019 Sep 27;11(10): Authors: Maino Vieytes CA, Mondul AM, Li Z, Zarins KR, Wolf GT, Rozek LS, Arthur AE Abstract No studies, to date, have examined the relationship between dietary fiber and recurrence or survival after head and neck cancer diagnosis. The aim of this study was to dete
- Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis.Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis. Int J Mol Sci. 2019 Sep 27;20(19): Authors: Nowicka Z, Stawiski K, Tomasik B, Fendler W Abstract Head and neck squamous cell carcinomas (HNSCCs) contribute to over 300,000 deaths every year worldwide. Although the survival rates have improved in some groups of patients, mostly due to new treatment options and the i
- Autologous Fat Grafting for Craniofacial Reconstruction in Oncologic Patients.Autologous Fat Grafting for Craniofacial Reconstruction in Oncologic Patients. Medicina (Kaunas). 2019 Sep 29;55(10): Authors: Drochioi CI, Sulea D, Timofte D, Mocanu V, Popescu E, Costan VV Abstract Due to the anatomical and functional complexity of the region, craniofacial tumor removal requires some of the most challenging surgical approaches, often complemented with advanced chemo-radiotherapy te
- Relevance of Neurotrophin Receptors CD271 and TrkC for Prognosis, Migration, and Proliferation in Head and Neck Squamous Cell Carcinoma.Relevance of Neurotrophin Receptors CD271 and TrkC for Prognosis, Migration, and Proliferation in Head and Neck Squamous Cell Carcinoma. Cells. 2019 Sep 28;8(10): Authors: Foerster Y, Stöver T, Wagenblast J, Diensthuber M, Balster S, Gabrielpillai J, Petzold H, Geissler C Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and often has a poor prognosis. T
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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