The global MRI community has lost one of its major pioneers in Ian Robert Young,...Read more on AuntMinnieEurope.comRelated Reading: Ronald Grainger: Radiology loses one of its greats
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BULLETIN BOARD Butler Eagle
Discovery: Why we refused elderly man's R14m insurance claim Fin24
Risk factors for head and neck cancer among WTC responders identified News-Medical.net
Machine learning improves the diagnosis of patients with head and neck cancers EurekAlert
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E-cigs latest example of product safety - public disconnect The CT Mirror
Free Women's Hormone Seminar at St. Moritz Medical Center The Union of Grass Valley
Differentiated Thyroid Cancer Therapeutics Market by Regional Segmentation, Major Players, Size, Market Dynamics & Forecast 2024 The Charterian
Chernobyl's Infamous Reactor 4 Control Room Is Now Open to Tourists Gizmodo
Lenvima-Keytruda Maintains Positive Results in Endometrial Cancer, Study Shows Immuno-Oncology News
Medical staffers are experts. But my hospital travails show why they can get it dangerously wrong. The Washington Post
Workers fight to keep coal ash regulations in place Eyewitness News (WEHT/WTVW)
Cancer data provide insights into occurrence, overdiagnosis, and treatment advances: Analysis of 40 years of epidemiological data illustrates the importance of considering both incidence and death rates when looking at cancer trends Science Daily
Researchers 3D Print Device to Reduce Mental Nerve Injury During Transoral Thyroidectomy 3DPrint.com
Some Michigan cows are contaminated with PFAS, but the state won't test milk Detroit Metro Times
How our lifestyle increases the risk of breast cancer CNA
Vantage Esmo 2019 roundup Vantage
Eden Sassoon and Angie Everhart open up about breast implant illness Daily Mail
Why Did Rare Cancer Shrink on Its Own? MedPage Today
Popular heartburn drug ranitidine recalled: What you need to know and do - Harvard Health Blog Harvard Health
UAB opens new Multidisciplinary Endocrine Tumor Clinic UAB News
Interpace Diagnostics Signs Thyroid Cancer Test Coverage Deals With Three BCBS Plans 360Dx
Gemma Collins' weight loss jabs - the risks of the hunger fighting injections revealed Irish Mirror
New Data for BAVENCIO® (avelumab) for Advanced Cancers to Be Presented at ESMO 2019 PRNewswire
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Uno de los fenómenos más conocidos de la psicología en el ámbito académico es la profecía autocumplida, por el cual si un alumno piensa (cree) que va a suspender acabará suspendiendo. Igualmente se atribuye al profesor, así si un profesor piensa que está impartiendo clase en un “mal grupo” el número de suspensos en ese --- →
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Bolus-to-Infusion Time in Stroke Patients Treated with Alteplase on the CT Table: A Clinical Concern
Cerebrovasc Dis
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Ethiopian parents can't make up for effects of life shocks on children by spending more on education
Ethiopian parents try to level out the life chances least-advantaged children affected by early life shocks such as famine and low rainfall levels by investing more in their education.
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Mucosal associated invariant T cells and Vδ2+ γδ T cells in community acquired pneumonia: association of abundance in sputum with clinical severity and outcome. Clin Exp Immunol. 2019 Oct 06;: Authors: Hannaway RF, Wang X, Schneider M, Slow S, Cowan J, Brockway B, Schofield MR, Morgan XC, Murdoch DR, Ussher JE Abstract Mucosal-associated invariant T (MAIT) cells and Vδ2+ γδ T cells are anti-bacterial innate-like lymphocytes (ILLs) that are enriched in blood and mucosa. ILLs...
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Authors: Facchinetti F, Hollebecque A, Bahleda R, Loriot Y, Olaussen KA, Massard C, Friboulet L Abstract Precision oncology relies on the identification of molecular alterations, responsible for tumor initiation and growth, that are suitable targets of specific inhibitors. The development of FGFR inhibitors represents an edifying example of the rapid evolution in the field of targeted oncology, with 10 different FGFR tyrosine kinase inhibitors actually under clinical investigation. In parallel,...
Authors: Fontana E, Valeri N Abstract Different classes of BRAF mutations are present in colorectal and other cancers. Non-V600 mutations are rare; however, their detection rate will increase as the use of next-generation sequencing ramps up quickly in clinical practice. Different biochemical signalling pathways are active in non-V600 BRAF mutant cancers and may affect treatment response. PMID: 31585936 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
CONCLUSIONS: This study shows that mechanisms of resistance to lorlatinib are diverse and complex, requiring new therapeutic strategies to tailor treatment upon disease progression. PMID: 31585938 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
CONCLUSIONS: NeoTx is not only cytotoxic, but has pleiotropic, beneficial effects on all cellular and non-cellular components of PCa. Combinational approaches including immunotherapy may unleash long-term and more effective anti-tumor responses and improve prognosis of PCa. PMID: 31585935 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
Authors: Frankell AM, Smyth EC Abstract In gastric and gastroesophageal adenocarcinoma, ctDNA identifies molecular drivers missed using routine tumor biopsy, can refine patient selection for targeted therapy, and may be prognostic following surgical resection. However, lack of standardisation could impede adoption of this technology as a clinically useful tool; prospective validation in clinical trials is required. PMID: 31582518 [PubMed - as supplied by publisher] (Source: Clinical...
CONCLUSIONS: Contrary to dogma, tumor suppressive responses to TGF-β are retained in some advanced metastatic tumors. Safe deployment of TGF-β antagonists in the clinic will require good predictive biomarkers. PMID: 31582516 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
CONCLUSION: MRSI-based pHe-mapping can serve as a longitudinal monitoring instrument for viable tumors. As most liver tumors are hyperglycolytic creating microenvironmental acidosis, therapy-induced normalization of tumor-pHe may be used as a functional biomarker for positive therapeutic outcome. PMID: 31582517 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
Authors: Pegram MD, Miles D, Tsui CK, Zong Y Abstract Efficacy data from the KATHERINE clinical trial comparing ado-trastuzumab emtansine (T-DM1) to trastuzumab in patients with early-stage human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer with residual disease after neoadjuvant therapy (hazard ratio for invasive disease or death, 0.50; P<0.001). This establishes foundational precedent for antibody drug conjugates (ADCs) as effective therapy for treatment of...
CONCLUSIONS: I.t.-tavo-EP was safe and feasible without systemic toxicity. Sustained local expression of IL-12 protein and local inflammation led to systemic immune responses and clinically meaningful benefit in some patients. Gene electrotransfer, specifically i.t.-tavo-EP, warrants further investigation for immunotherapy of cancer. PMID: 31582519 [PubMed - as supplied by publisher] (Source: Clinical Cancer Research)
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