Abstract Background Recent studies have shown that gastrokine 1 (GKN1), an important tumor suppressor gene, is downregulated in Helicobacter pylori (H. pylori) infected gastric mucosa and gastric cancer. However, the underlying mechanism is poorly understood. Herein, we investigated the potential mechanism of H. pylori‐induced GKN1 downregulation. Materials and methods GKN1 and AU‐rich element RNA‐binding factor 1 (AUF1) expressions were assessed by quantitative real‐time PCR, Western blot,...
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