Isolated tonsilar infarction presenting with positional vertigo and nystagmus
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Eun Hye Oh1
Seo-Young Choi2
Kwang-Dong Choi2
Jae-Hwan Choi1
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1.Department of Neurology, Pusan National University School of Medicine, Research Institute for Convergence of Biomedical Science and TechnologyPusan National University Yangsan HospitalYangsanSouth Korea
2.Department of Neurology, Pusan National University HospitalPusan National University School of Medicine and Biomedical Research InstituteBusanSouth Korea
Letter to the Editors
First Online: 17 July 2019
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Dear Sirs,
The flocculus and paraflocculus (or tonsil) play a pivotal role in control of eye movements [1]. Based on animal experiment, it is suggested that the flocculus is more integral in governing vestibulo-ocular reflexes (VORs), whereas the tonsil mainly contributes to smooth pursuit (SP) [2, 3]. In humans, however, an isolated lesion of the tonsil is sparse [4, 5], and oculomotor findings of the tonsil lesion have been explored only in one patient [4]. We describe oculomotor abnormalities in a patient with positional vertigo as a result of unilateral infarction of the tonsil, and compare results with a previously reported patient [4].
A 71-year-old man with hypertension and diabetes mellitus developed positional vertigo. The vertigo was induced when his head was turned to either side in supine position. He also reported nausea and vomiting, but denied other neurological symptoms. Eye movement recording using video-oculography showed no spontaneous and gaze-evoked nystagmus. In...
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Compliance with ethical standards
Conflicts of interest
We have no disclosure of any competing interest.
Ethical standards
All the experiments followed the tenets of the Declaration of Helsinki and this study was approved by Institutional Review Board.
References
1.
Leigh RJ, Zee DS (2015) The neurology of eye movements, 5th edn. Oxford University Press, New York
CrossRefGoogle Scholar
2.
Rambold H, Churchland A, Selig Y, Jasmin L, Lisberger SG (2002) Partial ablations of the flocculus and ventral paraflocculus in monkeys cause linked deficits in smooth pursuit eye movements and adaptive modification of the VOR. J Neurophysiol. 87(2):912–924
CrossRefGoogle Scholar
3.
Nagao S, Kitamura T, Nakamura N, Hiramatsu T, Yamada J (1997) Differences of the primate flocculus and ventral paraflocculus in the mossy and climbing fiber input organization. J Comp Neurol. 382(4):480–498
CrossRefGoogle Scholar
4.
Lee SH, Park SH, Kim JS, Kim HJ, Yunusov F, Zee DS (2014) Isolated unilateral infarction of the cerebellar tonsil: ocular motor findings. Ann Neurol. 75(3):429–434
CrossRefGoogle Scholar
5.
Ogawa K, Suzuki Y, Akimoto T, Morita A, Hara M, Yoshihashi H, Kamei S, Soma M (2018) Clinical study on three patients with infarction of the vermis/tonsil in the cerebellum. J Stroke Cerebrovasc Dis. 27(11):2919–2925
CrossRefGoogle Scholar
6.
Park HK, Kim JS, Strupp M, Zee DS (2013) Isolated floccular infarction: impaired vestibular responses to horizontal head impulse. J Neurol. 260(6):1576–1582
CrossRefGoogle Scholar
7.
Yacovino DA, Akly MP, Luis L, Zee DS (2018) The floccular syndrome: dynamic changes in eye movements and vestibulo-ocular reflex in isolated infarction of the cerebellar flocculus. Cerebellum 17(2):122–131
CrossRefGoogle Scholar
8.
Leung HC, Suh M, Kettner RE (2000) Cerebellar flocculus and paraflocculus Purkinje cell activity during circular pursuit in monkey. J Neurophysiol. 83(1):13–30
CrossRefGoogle Scholar
9.
Macdonald NK, Kaski D, Saman Y, Al-Shaikh Sulaiman A, Anwer A, Bamiou DE (2017) Central positional nystagmus: a systematic literature review. Front Neurol. 8:141
CrossRefGoogle Scholar
10.
Choi JY, Glasauer S, Kim JH, Zee DS, Kim JS (2018) Characteristics and mechanism of apogeotropic central positional nystagmus. Brain 141(3):762–775
CrossRefGoogle Scholar
11.
Bertholon P, Tringali S, Faye MB, Antoine JC, Martin C (2006) Prospective study of positional nystagmus in 100 consecutive patients. Ann Otol Rhinol Laryngol. 115(8):587–594
CrossRefGoogle Scholar
12.
Choi SY, Jang JY, Oh EH, Choi JH, Park JY, Lee SH, Choi KD (2018) Persistent geotropic positional nystagmus in unilateral cerebellar lesions. Neurology. 91(11):e1053–e1057
CrossRefGoogle Scholar
13.
Newlands SD, Vrabec JT, Purcell IM, Stewart CM, Zimmerman BE, Perachio AA (2003) Central projections of the saccular and utricular nerves in macaques. J Comp Neurol. 466(1):31–47
CrossRefGoogle Scholar
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© Springer-Verlag GmbH Germany, part of Springer Nature 2019
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Cite this article as:
Oh, E.H., Choi, SY., Choi, KD. et al. J Neurol (2019) 266: 2578. https://doi.org/10.1007/s00415-019-09468-w
Received
12 April 2019
Revised
10 July 2019
Accepted
11 July 2019
First Online
17 July 2019
DOI
https://doi.org/10.1007/s00415-019-09468-w
Publisher Name
Springer Berlin Heidelberg
Print ISSN
0340-5354
Online ISSN
1432-1459
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