IJMS, Vol. 20, Pages 4942: L-Alanine Exporter, AlaE, of Escherichia coli Functions as a Safety Valve to Enhance Survival under Feast Conditions International Journal of Molecular Sciences doi: 10.3390/ijms20194942 Authors: Satoshi Katsube Tasuke Ando Hiroshi Yoneyama The intracellular level of amino acids is determined by the balance between their anabolic and catabolic pathways. L-alanine is anabolized by three L-alanine synthesizing enzymes and catabolized by two racemases and...
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JCM, Vol. 8, Pages 1641: More Impaired Dynamic Ventilatory Muscle Oxygenation in Congestive Heart Failure than in Chronic Obstructive Pulmonary Disease Journal of Clinical Medicine doi: 10.3390/jcm8101641 Authors: Ming-Lung Chuang I-Feng Lin Meng-Jer Hsieh Patients with chronic obstructive pulmonary disease (COPD) and congestive heart failure (CHF) often have dyspnea. Despite differences in primary organ derangement and similarities in secondary skeletal muscle changes, both patient...
JCM, Vol. 8, Pages 1639: The Role of Physical Fitness in Cognitive-Related Biomarkers in Persons at Genetic Risk of Familial Alzheimer’s Disease Journal of Clinical Medicine doi: 10.3390/jcm8101639 Authors: Tsai Sun Kuo Pai Introduction: Nondemented people with a family history of Alzheimer’s disease (ADFH) and the ApoE-4 allele have been demonstrated to show a trend for a higher probability of cognitive decline and aberrant levels of cognitive-related biomarkers....
JCM, Vol. 8, Pages 1637: Effects of rAAV-Mediated sox9 Overexpression on the Biological Activities of Human Osteoarthritic Articular Chondrocytes in Their Intrinsic Three-Dimensional Environment Journal of Clinical Medicine doi: 10.3390/jcm8101637 Authors: Oliver Daniels Janina Frisch Jagadeesh K. Venkatesan Ana Rey-Rico Gertrud Schmitt Magali Cucchiarini Gene therapy for osteoarthritis offers powerful, long-lasting tools that are well adapted to treat such a slow, progressive...
JCM, Vol. 8, Pages 1638: A Systematic Review and Meta-Analysis of the Impact of Mindfulness Based Interventions on Heart Rate Variability and Inflammatory Markers Journal of Clinical Medicine doi: 10.3390/jcm8101638 Authors: Rådmark Sidorchuk Osika Niemi Mindfulness Based Interventions (MBIs) have recently been increasingly used in clinical settings, and research regarding their effects on health has grown rapidly. However, with regard to the physiological effects of mindfulness...
JCM, Vol. 8, Pages 1640: Management Strategies for Antidepressant-Related Sexual Dysfunction: A Clinical Approach Journal of Clinical Medicine doi: 10.3390/jcm8101640 Authors: Angel L. Montejo Nieves Prieto Rubén de Alarcón Nerea Casado-Espada Javier de la Iglesia Laura Montejo Major depressive disorder is a serious mental disorder in which treatment with antidepressant medication is often associated with sexual dysfunction (SD). Given its intimate nature, treatment emergent...
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JoF, Vol. 5, Pages 94: External Quality Assessment Evaluating the Ability of Dutch Clinical Microbiological Laboratories to Identify Candida auris Journal of Fungi doi: 10.3390/jof5040094 Authors: Jochem B. Buil Henrich A. L. van der Lee Ilse Curfs-Breuker Paul E. Verweij Jacques F. Meis Background: Candida auris is a yeast that is causing nosocomial outbreaks in healthcare facilities around the world. There is a risk of the misidentification of C. auris with matrix-assisted...
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Medicina, Vol. 55, Pages 676: Oral Health: The First Step to Well-Being Medicina doi: 10.3390/medicina55100676 Authors: Fiorillo Scientific research in the medical field shows this constantly: health starts from the mouth. Having good oral health nowadays is not only aimed at tooth health, but as amply demonstrated in the literature, it is a starting point for the general health and well-being of our body. Retracing the latest scientific findings that demonstrate an interpolation between...
Medicina, Vol. 55, Pages 675: Association of Higher Advanced Oxidation Protein Products (AOPPs) Levels in Patients with Diabetic and Hypertensive Nephropathy Medicina doi: 10.3390/medicina55100675 Authors: Conti Caccamo Siligato Gembillo Satta Pazzano Carucci Carella Campo Salvo Santoro Background and Objectives: Diabetes mellitus (DM) and hypertension (HT) are characterized by cell damage caused by inflammatory and metabolic mechanisms induced...
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Molecules, Vol. 24, Pages 3612: Applicability of a Monolithic Column for Separation of Isoquinoline Alkalodis from Chelidonium majus Extract Molecules doi: 10.3390/molecules24193612 Authors: Staniak Wójciak-Kosior Sowa Strzemski Sawicki Dresler Tyszczuk-Rotko Isoquinoline alkaloids are the main group of secondary metabolites present in Chelidonium majus extracts, and they are still the object of interest of many researchers. Therefore, the development of methods...
Molecules, Vol. 24, Pages 3611: Polyamidoamide Dendrimers and Cross-Linking Agents for Stabilized Bioenzymatic Resistant Metal-Free Bovine Collagen Molecules doi: 10.3390/molecules24193611 Authors: Beghetto Gatto Conca Bardella Scrivanti The work reports the use of polyamidoamine dendrimers (PAMAM) and a cross-linking agent, 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide/N-hydroxysuccinimide (EDC/NHS) or 4-(4,6-dimethoxy[1,3,5]triazin-2-yl)-4-methyl-morpholinium chloride...
Molecules, Vol. 24, Pages 3609: Gold Nanoparticles as Boron Carriers for Boron Neutron Capture Therapy: Synthesis, Radiolabelling and In vivo Evaluation Molecules doi: 10.3390/molecules24193609 Authors: Pulagam Gona Gómez-Vallejo Meijer Zilberfain Estrela-Lopis Baz Cossío Llop Background: Boron Neutron Capture Therapy (BNCT) is a binary approach to cancer therapy that requires accumulation of boron atoms preferentially in tumour cells. This can be achieved...
Molecules, Vol. 24, Pages 3610: Studies of Halogen Bonding Induced by Pentafluorosulfanyl Aryl Iodides: A Potential Group of Halogen Bond Donors in a Rational Drug Design Molecules doi: 10.3390/molecules24193610 Authors: Sumii Sasaki Tsuzuki Shibata The activation of halogen bonding by the substitution of the pentafluoro-λ6-sulfanyl (SF5) group was studied using a series of SF5-substituted iodobenzenes. The simulated electrostatic potential values of SF5-substituted...
Molecules, Vol. 24, Pages 3607: Migration Studies of Two Common Components of UV-curing Inks into Food Simulants Molecules doi: 10.3390/molecules24193607 Authors: Miguel A. Lago Raquel Sendón Juana Bustos María T. Nieto Perfecto Paseiro Losada Ana Rodríguez-Bernaldo de Quirós The Rapid Alert System for Food and Feed (RASFF) has reported many cases of different UV curing inks components in foodstuffs during the last few years. These contaminants reach foodstuffs mainly...
Molecules, Vol. 24, Pages 3606: Fabrication of pH-Sensitive Tetramycin Releasing Gel and Its Antibacterial Bioactivity against Ralstonia solanacearum Molecules doi: 10.3390/molecules24193606 Authors: Xiaozhou Ma Shunyu Xiang Huijun Xie Linhai He Xianchao Sun Yongqiang Zhang Jin Huang Ralstonia solanacearum (R. solanacearum)-induced bacterial wilt of the nightshade family causes a great loss in agricultural production annually. Although there has been some efficient...
Molecules, Vol. 24, Pages 3608: In Silico and In Vitro Anti-Helicobacter Pylori Effects of Combinations of Phytochemicals and Antibiotics Molecules doi: 10.3390/molecules24193608 Authors: Pedro Fong Chon-Hou Hao Chi-Cheng Io Pou-Io Sin Li-Rong Meng Helicobacter pylori infection is a WHO class 1 carcinogenic factor of gastric adenocarcinoma. In the past decades, many studies have demonstrated the increasing trend of antibiotic resistance and pointed out the necessity of new...
Molecules, Vol. 24, Pages 3605: In vitro Fermentation of Polysaccharides from Aloe vera and the Evaluation of Antioxidant Activity and Production of Short Chain Fatty Acids Molecules doi: 10.3390/molecules24193605 Authors: Antonio Tornero-Martínez Rubén Cruz-Ortiz María Eugenia Jaramillo-Flores Perla Osorio-Díaz Sandra Victoria Ávila-Reyes Guadalupe Monserrat Alvarado-Jasso Rosalva Mora-Escobedo Soluble or fermentable fibre has prebiotic effects that can be used in...
Molecules, Vol. 24, Pages 3603: High-Throughput 1H-Nuclear Magnetic Resonance-Based Screening for the Identification and Quantification of Heartwood Diterpenic Acids in Four Black Pine (Pinus nigra Arn.) Marginal Provenances in Greece Molecules doi: 10.3390/molecules24193603 Authors: Kostas Ioannidis Eleni Melliou Prokopios Magiatis A high-throughput quantitative Nuclear Magnetic Resonance 1H-NMR method was developed and applied to screen the quantity of the diterpenic resin acids...
Molecules, Vol. 24, Pages 3599: Biological Evaluation of Natural and Synthesized Homovanillic Acid Esters as Inhibitors of Intestinal Fatty Acid Uptake in Differentiated Caco-2 Cells Molecules doi: 10.3390/molecules24193599 Authors: Barbara Lieder Joachim Hans Fabia Hentschel Katrin Geissler Jakob Ley With raising prevalence of obesity, the regulation of human body fat is increasingly relevant. The modulation of fatty acid uptake by enterocytes represents a promising target...
Molecules, Vol. 24, Pages 3604: Ferrocene-Based Compounds with Antimalaria/Anticancer Activity Molecules doi: 10.3390/molecules24193604 Authors: Sijongesonke Peter Blessing Atim Aderibigbe Malaria and cancer are chronic diseases. The challenge with drugs available for the treatment of these diseases is drug toxicity and resistance. Ferrocene is a potent organometallic which have been hybridized with other compounds resulting in compounds with enhanced biological activity such as antimalarial...
Molecules, Vol. 24, Pages 3602: Identification of Cannabis sativa L. (hemp) Retailers by Means of Multivariate Analysis of Cannabinoids Molecules doi: 10.3390/molecules24193602 Authors: Sara Palmieri Marcello Mascini Antonella Ricci Federico Fanti Chiara Ottaviani Claudio Lo Sterzo Manuel Sergi In this work, the concentration of nine cannabinoids, six neutral cannabinoids (THC, CBD, CBC, CBG, CBN and CBDV) and three acidic cannabinoids (THCA CBGA and CBDA), was used...
Molecules, Vol. 24, Pages 3601: Combination Therapy Strategies for the Treatment of Malaria Molecules doi: 10.3390/molecules24193601 Authors: Sibusiso Alven Blessing Aderibigbe Malaria is a vector- and blood-borne infection that is responsible for a large number of deaths around the world. Most of the currently used antimalarial therapeutics suffer from drug resistance. The other limitations associated with the currently used antimalarial drugs are poor drug bioavailability, drug...
Molecules, Vol. 24, Pages 3600: Phenomenological Inferences on the Kinetics of a Mechanically Activated Knoevenagel Condensation: Understanding the “Snowball” Kinetic Effect in Ball Milling Molecules doi: 10.3390/molecules24193600 Authors: Maria Carta Stuart L. James Francesco Delogu We focus on understanding the kinetics of a mechanically activated Knoevenagel condensation conducted in a ball mill, that is characterized by sigmoidal kinetics and the formation of a rubber-like...
Molecules, Vol. 24, Pages 3598: Inside the Black Box: What Makes SELEX Better? Molecules doi: 10.3390/molecules24193598 Authors: Natalia Komarova Alexander Kuznetsov Aptamers are small oligonucleotides that are capable of binding specifically to a target, with impressive potential for analysis, diagnostics, and therapeutics applications. Aptamers are isolated from large nucleic acid combinatorial libraries using an iterative selection process called SELEX (Systematic Evolution of...
Molecules, Vol. 24, Pages 3596: Synthesis of a Di-Mycoloyl Tri-Arabinofuranosyl Glycerol Fragment of the Mycobacterial Cell Wall, Based on Synthetic Mycolic Acids Molecules doi: 10.3390/molecules24193596 Authors: Ali Mohammed Dulayymi Baird Fragments of mycobacterial cell walls such as arabinoglycerol mycolate and dimycoloyl diarabinoglycerol, comprising complex mixtures of mycolic acids, have immunostimulatory and antigenic properties. A related di-mycoloyl tri-arabinofuranosyl...
Molecules, Vol. 24, Pages 3597: Detailed Analysis of the Influencing Parameters on the Self-Healing Behavior of Dynamic Urea-Crosslinked Poly(methacrylate)s Molecules doi: 10.3390/molecules24193597 Authors: Abend Zechel Schubert Hager For this paper, the self-healing ability of poly(methacrylate)s crosslinked via reversible urea bonds was studied in detail. In this context, the effects of healing time and temperature on the healing process were investigated. Furthermore,...
Molecules, Vol. 24, Pages 3593: Broccoli or Sulforaphane: Is It the Source or Dose That Matters? Molecules doi: 10.3390/molecules24193593 Authors: Yoko Yagishita Jed W. Fahey Albena T. Dinkova-Kostova Thomas W. Kensler There is robust epidemiological evidence for the beneficial effects of broccoli consumption on health, many of them clearly mediated by the isothiocyanate sulforaphane. Present in the plant as its precursor, glucoraphanin, sulforaphane is formed through the actions...
Molecules, Vol. 24, Pages 3594: One-Pot Metal-Free Synthesis of 3-CF3-1,3-Oxazinopyridines by Reaction of Pyridines with CF3CO-Acetylenes Molecules doi: 10.3390/molecules24193594 Authors: Muzalevskiy Sizova Belyaeva Trofimov Nenajdenko The reaction of pyridines with trifluoroacetylated acetylenes was investigated. It was found that the reaction of various pyridines with two molecules of CF3CO-acetylenes proceeds under mild metal-free conditions. As a result, efficient...
Molecules, Vol. 24, Pages 3595: Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins Molecules doi: 10.3390/molecules24193595 Authors: Cao Wu Pan Wang Toad venom (Chansu), a traditional Chinese medicine (TCM), has been widely used for treating various cancer. However, it is considerably difficult to evaluate the quality of Chansu due to its complex chemical compositions. Hence, finding the characteristic...
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MTI, Vol. 3, Pages 66: Reorganize Your Blogs: Supporting Blog Re-visitation with Natural Language Processing and Visualization Multimodal Technologies and Interaction doi: 10.3390/mti3040066 Authors: Shuo Niu D. Scott McCrickard Timothy L. Stelter Alan Dix G. Don Taylor Temporally-connected personal blogs contain voluminous textual content, presenting challenges in re-visiting and reflecting on experiences. Other data repositories have benefited from natural language processing...
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Nutrients, Vol. 11, Pages 2398: An Umbrella Review of Systematic Reviews on Food Choice and Nutrition Published between 2017 and-2019 Nutrients doi: 10.3390/nu11102398 Authors: Perez-Cueto The objective of this umbrella review was to provide an update on the latest knowledge in the field of food choice and nutrition. Databases Scopus and ISI-Web of Science were searched for “food choice” AND nutrition. Papers were included if they were systematic reviews published...
Nutrients, Vol. 11, Pages 2396: Recent Advances in Kaempferia Phytochemistry and Biological Activity: A Comprehensive Review Nutrients doi: 10.3390/nu11102396 Authors: Elshamy Mohamed Essa Abd-ElGawad Alqahtani Shahat Yoneyama Farrag Noji El-Seedi Umeyama Paré Hegazy Background: Plants belonging to the genus Kaempferia (family: Zingiberaceae) are distributed in Asia, especially in the southeast region, and Thailand. They have been widely...
Nutrients, Vol. 11, Pages 2397: Daily Fructose Traces Intake and Liver Injury in Children with Hereditary Fructose Intolerance Nutrients doi: 10.3390/nu11102397 Authors: Di Dato Spadarella Puoti Caprio Pagliardini Zuppaldi Vallone Fecarotta Esposito Iorio Parenti Spagnuolo Background: Hereditary fructose intolerance (HFI) is a rare genetic disorder of fructose metabolism due to aldolase B enzyme deficiency. Treatment consists of fructose,...
Nutrients, Vol. 11, Pages 2395: A Study of the Food Environment at Australian Family Day Care Nutrients doi: 10.3390/nu11102395 Authors: Wallace Mills Overweight and obesity in childhood is a significant public health issue. Family day care (FDC) offers a setting where good eating habits can be nurtured in young children, yet often the food environment is unhealthy. This study aims to determine FDC educators’ knowledge and confidence about nutrition and the barriers and...
Nutrients, Vol. 11, Pages 2394: Fermented Goat Milk Consumption Enhances Brain Molecular Functions during Iron Deficiency Anemia Recovery Nutrients doi: 10.3390/nu11102394 Authors: Moreno-Fernández López-Aliaga García-Burgos Alférez Díaz-Castro Iron deficiency anemia (IDA) is one of the most prevalent nutritional deficiencies worldwide. Iron plays critical roles in nervous system development and cognition. Despite the known detrimental consequences of IDA on cognition,...
Nutrients, Vol. 11, Pages 2393: Food Components and Dietary Habits: Keys for a Healthy Gut Microbiota Composition Nutrients doi: 10.3390/nu11102393 Authors: Rinninella Cintoni Raoul Lopetuso Scaldaferri Pulcini Miggiano Gasbarrini Mele The gut microbiota is a changing ecosystem, containing trillions of bacteria, continuously shaped by many factors, such as dietary habits, seasonality, lifestyle, stress, antibiotics use, or diseases. A healthy host–microorganisms...
Nutrients, Vol. 11, Pages 2392: The Role of Dietary Fiber in Rheumatoid Arthritis Patients: A Feasibility Study Nutrients doi: 10.3390/nu11102392 Authors: Julian Häger Holger Bang Melanie Hagen Michael Frech Pascal Träger Maria V. Sokolova Ulrike Steffen Koray Tascilar Kerstin Sarter Georg Schett Jürgen Rech Mario M. Zaiss Short-chain fatty acids are microbial metabolites that have been shown to be key regulators of the gut–joint axis in animal...
Nutrients, Vol. 11, Pages 2391: Validity of a Food and Fluid Exercise Questionnaire for Macronutrient Intake during Exercise against Observations Nutrients doi: 10.3390/nu11102391 Authors: Floris C. Wardenaar Daan Hoogervorst Nancy van der Burg Joline Versteegen Wonsuk Yoo Natasha Tasevska Information about the accuracy of self-reported food and fluid intake during competitions is scarce. The objective of this study was to validate a previously developed food and fluid...
Nutrients, Vol. 11, Pages 2390: Heart Histopathology and Mitochondrial Ultrastructure in Aged Rats Fed for 24 Months on Different Unsaturated Fats (Virgin Olive Oil, Sunflower Oil or Fish Oil) and Affected by Different Longevity Nutrients doi: 10.3390/nu11102390 Authors: Navarro-Hortal Ramírez-Tortosa Varela-López Romero-Márquez Ochoa Ramírez-Tortosa Forbes-Hernández Granados-Principal Battino Quiles Diet plays a decisive role in heart physiology,...
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