- Journal of Surgical Education Gender Bias Experiences of Female Surgical Trainees Publication.........Journal of Surgical Education Gender Bias Experiences of Female Surgical Trainees Publication......Journal of Surgical Education Gender Bias Experiences of Female Surgical Trainees Publication...Journal of Surgical EducationGender Bias Experiences of Female Surgical TraineesPublication date: Available online 7 October 2019Source: Journal of Surgical EducationAuthor(s): K. Lauren Barnes, Lauren McGuire, Gena Dunivan, Andrew L. Sussman, Rohini McKe
- Journal of Surgical Education Gender Bias Experiences of Female Surgical Trainees Publication...Journal of Surgical EducationGender Bias Experiences of Female Surgical TraineesPublication date: Available online 7 October 2019Source: Journal of Surgical EducationAuthor(s): K. Lauren Barnes, Lauren McGuire, Gena Dunivan, Andrew L. Sussman, Rohini McKeeObjectiveMedical schools now average approximately 50% female students, yet a disproportionate number of women continue to choose nonsurgical over surgical specialties. Once in training, studies
- Journal of Medical Imaging and Radiation Oncology Continuing Professional Development Journal...Journal of Medical Imaging and Radiation OncologyContinuing Professional DevelopmentJournal of Medical Imaging and Radiation OncologySun Oct 06, 2019 08:40Issue InformationJournal of Medical Imaging and Radiation OncologySun Oct 06, 2019 08:40American Society for Stereotactic and Functional NeurosurgeryStereotactic Radiosurgery for Pediatric and Adult Intracranial and Spinal EpendymomasObjective/Background: We report efficacy and toxicity outcome
- Breath-hold compressed-sensing 3D MR cholangiopancreatography compared to free-breathing 3D MR cholangiopancreatography:...Breath-hold compressed-sensing 3D MR cholangiopancreatography compared to free-breathing 3D MR cholangiopancreatography: prospective study of image quality and diagnostic performance in pancreatic disordersAbstract Purpose To compare image quality and diagnostic performance of three magnetic resonance cholangiopancreatography (MRCP) protocols in patients with suspected pancreatic abnormalities: free-breathing standard 3D-MRCP (STD), free-breathin
- Intra-individual behavioural variability: a trait under genetic control [NEW RESULTS]Intra-individual behavioural variability: a trait under genetic control [NEW RESULTS]: When individuals are measured more than once in the same context they do not behave in exactly the same way each time. The degree of predictability differs between individuals, with some individuals showing low levels of variation around their behavioural mean while others show high levels of variation. This intra-individual variation in behaviour has received
- Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells<i>Pparg</i> promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells:
- Insects as phyllosphere microbiome engineers: effects of aphids on a plant pathogen. [NEW RESULTS]Insects as phyllosphere microbiome engineers: effects of aphids on a plant pathogen. [NEW RESULTS]: Insect herbivores are common in the phyllosphere, the above-ground parts of plants, and encounter diverse plant-associated bacteria there, yet how these organisms interact remains largely unknown. Strains of the bacterium Pseudomonas syringae grow well epiphytically and have been shown to grow within and kill hemipteran insects like the pea aphid,
- A comparative study of the microtensile bond strength and microstructural differences between sclerotic and Normal dentine after surface pretreatmentA comparative study of the microtensile bond strength and microstructural differences between sclerotic and Normal dentine after surface pretreatment: AbstractBackgroundThe resin bond strength of sclerotic dentine is significantly lower than that of the normal dentine, which paused a challenge for bonding procedures clinically. The aim of this study was to compare the effects of different surface pretreatments on the micro-tensile bond strength a
- Treatment of dentigerous cysts with a modified Hawley plate in children: report of two cases with radiographic resultsTreatment of dentigerous cysts with a modified Hawley plate in children: report of two cases with radiographic results: Publication date: Available online 7 October 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): J. Nohra, A.R. Kassir, H. Akel, M. DagherAbstractDentigerous cysts in young adults may compromise the natural evolution of the dentition and can be treated surgically or non-surgically. We report the minimally-inv
- Viral <i>N</i><sup>6</sup>-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virusViral <i>N</i><sup>6</sup>-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus:
- Antibiotic prophylaxis for general dentistsDesigning a customized clinical practice guideline regarding antibiotic prophylaxis for Iranian general dentists: AbstractBackgroundClinical practice guidelines produced by developed countries seemed to be not completely feasible for developing countries due to their different local context. In this study, we designed a customized guideline about antibiotic prophylaxis before dental procedures for Iranian general dentists.MethodsThis study was co
- Exposure to asbestos and the risk of colorectal cancer mortality: a systematic review and meta-analysisExposure to asbestos and the risk of colorectal cancer mortality: a systematic review and meta-analysis: Asbestos exposure is associated with mesothelioma and cancer of the lung, larynx and ovary. However, the association between asbestos exposure and colorectal cancer is controversial despite several systematic reviews of the literature, including a number of meta-analyses. We performed a systematic review and meta-analysis to evaluate quantitat
- Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid FibrosarcomaRecurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid Fibrosarcoma: Sclerosing epithelioid fibrosarcoma (SEF) is an aggressive soft tissue sarcoma, characterized by a distinctive epithelioid phenotype in a densely sclerotic collagenous stroma, that shows frequent MUC4 immunoreactivity and recurrent gene fusions, often involving EWSR1 gene. A pathogenetic link with low-grade fibromyxoid sarcoma (LGFMS) ha
- Prostate Carcinoma Grade and Length But Not Cribriform Architecture at Positive Surgical Margins are Predictive For Biochemical Recurrence After Radical ProstatectomyProstate Carcinoma Grade and Length But Not Cribriform Architecture at Positive Surgical Margins are Predictive For Biochemical Recurrence After Radical Prostatectomy: Postoperative biochemical recurrence occurs in up to 40% of prostate carcinoma patients treated with radical prostatectomy. Primary tumor grade and cribriform architecture are important parameters for clinical outcome; however, their relevance at positive surgical margins has not b
- Visual Mismatch and Predictive Coding: A Computational Single-Trial ERP Study.Visual Mismatch and Predictive Coding: A Computational Single-Trial ERP Study.: Related ArticlesVisual Mismatch and Predictive Coding: A Computational Single-Trial ERP Study.J Neurosci. 2018 04 18;38(16):4020-4030Authors: Stefanics G, Heinzle J, Horváth AA, Stephan KEAbstract Predictive coding (PC) posits that the brain uses a generative model to infer the environmental causes of its sensory data and uses precision-weighted prediction e
- Acute Vertigo in a Patient with Long-Term Organic Solvent Exposure: Importance of a Comprehensive Audio-Vestibular Test Battery.Acute Vertigo in a Patient with Long-Term Organic Solvent Exposure: Importance of a Comprehensive Audio-Vestibular Test Battery.: Related ArticlesAcute Vertigo in a Patient with Long-Term Organic Solvent Exposure: Importance of a Comprehensive Audio-Vestibular Test Battery.J Am Acad Audiol. 2019 Oct 03;:1-6Authors: Maheu M, Champoux F, Fuente AAbstract BACKGROUND: Ototoxicity induced by organic solvents has been identified in several grou
- Ensuring Sustainability of Needed Antibiotics: Aiming for the DART BoardEnsuring Sustainability of Needed Antibiotics: Aiming for the DART Board: Antibiotic resistance has been a major concern in the past few decades. Current initiatives to incentivize the development of antibiotics for resistant pathogens have yielded disappointing results because many recently approved antibiotics do not address clinical unmet needs or provide redundant coverage. In this article, the authors propose a different approach for guiding
- Optogenetic stimulation of cochlear neurons activates the auditory pathway and restores auditory-driven behavior in deaf adult gerbils.Optogenetic stimulation of cochlear neurons activates the auditory pathway and restores auditory-driven behavior in deaf adult gerbils.: Related ArticlesOptogenetic stimulation of cochlear neurons activates the auditory pathway and restores auditory-driven behavior in deaf adult gerbils.Sci Transl Med. 2018 07 11;10(449):Authors: Wrobel C, Dieter A, Huet A, Keppeler D, Duque-Afonso CJ, Vogl C, Hoch G, Jeschke M, Moser TAbstract Cochlear
- Interaction Between Electric and Acoustic Stimulation Influences Speech Perception in Ipsilateral EAS UsersInteraction Between Electric and Acoustic Stimulation Influences Speech Perception in Ipsilateral EAS Users: Objectives: The aim of this study was to determine electric-acoustic masking in cochlear implant users with ipsilateral residual hearing and different electrode insertion depths and to investigate the influence on speech reception. The effects of different fitting strategies—meet, overlap, and a newly developed masking adjusted fitting (UN
- Paeonol antagonizes oncogenesis of osteosarcoma by inhibiting the function of TLR4/MAPK/NF-κB pathway.Paeonol antagonizes oncogenesis of osteosarcoma by inhibiting the function of TLR4/MAPK/NF-κB pathway.: Related ArticlesPaeonol antagonizes oncogenesis of osteosarcoma by inhibiting the function of TLR4/MAPK/NF-κB pathway.Acta Histochem. 2019 Oct 03;:151455Authors: Zhou J, Liu Q, Qian R, Liu S, Hu W, Liu ZAbstract As the the major functional component of Paeonia suffruticosa, paeonol (PAE) has shown its potential to inhibit the progressio
- Cases in Precision Medicine: APOL1 and Genetic Testing in the Evaluation of Chronic Kidney Disease and Potential TransplantCases in Precision Medicine: APOL1 and Genetic Testing in the Evaluation of Chronic Kidney Disease and Potential Transplant: This article discusses potential indications for genetic testing in an African American patient with chronic kidney disease who is being evaluated for a kidney transplant. Two known risk variants in the APOL1 (apolipoprotein L1) gene predispose to kidney disease and are found almost exclusively in persons of African ances
- Deadly Vasculitides and Reversed Racial/Ethnic Disparity?Deadly Vasculitides and Reversed Racial/Ethnic Disparity?: Steinberg and colleagues report high but slowly declining U.S. mortality trends in patients with antineutrophil cytoplasmic autoantibody–associated vasculitides. The editorialist discusses the findings and why he believes that the apparently better outcomes observed in typically disadvantaged patient groups may hold clues to structural causes of health disparities.
- Journal of Sleep Research Relationship between obstructive sleep apnoea, other cardiovascular...Journal of Sleep ResearchRelationship between obstructive sleep apnoea, other cardiovascular risk factors and cardiovascular diseaseJournal of Sleep ResearchThu Oct 03, 2019 10:47Body composition and Obstructive Sleep Apnoea severity in an Acute Coronary Syndrome populationJournal of Sleep ResearchThu Oct 03, 2019 10:47Central sleep apnoea (CSA) – could it be due to non‐traditional risk factors?Journal of Sleep ResearchThu Oct 03, 2019 10:47NREM
- Genioglossus reflex responses to brief pulses of negative pharyngeal pressure in people with multiple sclerosisGenioglossus reflex responses to brief pulses of negative pharyngeal pressure in people with multiple sclerosisH. Hensen1,2, A.M. Osman3, J. Carberry3, S. Gandevia1, A. Krishnan4, D.J. Eckert1,31Neuroscience Research Australia, Randwick, Australia; 2School of Medical Sciences, University of New South Wales, Sydney, Australia; 3Adelaide Institute for Sleep Health, Flinders University, Adelaide, Australia; 4Prince of Wales Clinical School, Sydney,
- CPAP treatment, glycaemia and diabetes risk in obstructive sleep apnoea with comorbid cardiovascular diseaseCPAP treatment, glycaemia and diabetes risk in obstructive sleep apnoea with comorbid cardiovascular diseaseK. Loffler1, C.S. Anderson2, R.D. McEvoy1, L.F. Drager31Flinders University, Bedford Park, Adelaide, Australia; 2The George Institute for Global Health, Peking University Health Science Center, Beijing, China; 3Instituto do Coracao (Incor) and Hospital Universitario, Faculty of Medicine, University of Sao Paulo, Sao Paolo, BrazilIntroductio
- Primary caregiver education level and sleep problems in children with autism spectrum disorderPrimary caregiver education level and sleep problems in children with autism spectrum disorder: AbstractIn children with autism spectrum disorder, there have been equivocal results regarding primary caregiver education level and its influence on sleep. Thus, we assessed if lower primary caregiver education level is associated with more sleep problems. We evaluated 4,636 children with autism spectrum disorder in the Autism Speaks Autism Treatment
- Cerebral Damage after Carbon Monoxide Poisoning: A Longitudinal Diffusional Kurtosis Imaging Study [FUNCTIONAL]Cerebral Damage after Carbon Monoxide Poisoning: A Longitudinal Diffusional Kurtosis Imaging Study [FUNCTIONAL]: BACKGROUND AND PURPOSE:Previous DTI cross-sectional studies have showed the cerebral damage feature was different in the three clinical stages after carbon monoxide poisoning. Diffusional kurtosis imaging (DKI) is an advanced diffusion imaging model and considered to better provide microstructural contrast in comparison with DTI parame
- Effect of Time Elapsed since Gadolinium Administration on Atherosclerotic Plaque Enhancement in Clinical Vessel Wall MR Imaging Studies [ADULT BRAIN]Effect of Time Elapsed since Gadolinium Administration on Atherosclerotic Plaque Enhancement in Clinical Vessel Wall MR Imaging Studies [ADULT BRAIN]: SUMMARY:Vessel wall MR imaging is a useful tool for the evaluation of intracranial atherosclerotic disease. Enhancement can be particularly instructive. This study investigated the impact of the duration between contrast administration and image acquisition. The cohort with the longest duration had
- PACS Integration of Semiautomated Imaging Software Improves Day-to-Day MS Disease Activity Detection [ADULT BRAIN]PACS Integration of Semiautomated Imaging Software Improves Day-to-Day MS Disease Activity Detection [ADULT BRAIN]: BACKGROUND AND PURPOSE:The standard for evaluating interval radiologic activity in MS, side-by-side MR imaging comparison, is restricted by its time-consuming nature and limited sensitivity. VisTarsier, a semiautomated software for comparing volumetric FLAIR sequences, has shown better disease-activity detection than conventional co
- Diagnostic Impact of Intracranial Vessel Wall MRI in 205 Patients with Ischemic Stroke or TIA [ADULT BRAIN]Diagnostic Impact of Intracranial Vessel Wall MRI in 205 Patients with Ischemic Stroke or TIA [ADULT BRAIN]: BACKGROUND AND PURPOSE:Secondary prevention of ischemic stroke depends on determining the cause of the initial ischemic event, but standard investigations often fail to identify a cause or identify multiple potential causes. The purpose of this study was to characterize the impact of intracranial vessel wall MR imaging on the etiologic cla
- Virtual Monoenergetic Images from Spectral Detector CT Enable Radiation Dose Reduction in Unenhanced Cranial CT [PATIENT SAFETY]Virtual Monoenergetic Images from Spectral Detector CT Enable Radiation Dose Reduction in Unenhanced Cranial CT [PATIENT SAFETY]: BACKGROUND AND PURPOSE:Our aim was to evaluate whether improved gray-white matter differentiation in cranial CT by means of 65- keV virtual monoenergetic images enables a radiation dose reduction compared to conventional images.MATERIALS AND METHODS:One hundred forty consecutive patients undergoing 171 spectral detecto
- Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance [ADULT BRAIN]Multinodular and Vacuolating Posterior Fossa Lesions of Unknown Significance [ADULT BRAIN]: SUMMARY:Multinodular and vacuolating neuronal tumor of the cerebrum is a rare supratentorial brain tumor described for the first time in 2013. Here, we report 11 cases of infratentorial lesions showing similar striking imaging features consisting of a cluster of low T1-weighted imaging and high T2-FLAIR signal intensity nodules, which we referred to as mul
- Board Certification Characteristics of Practicing Neuroradiologists [research-article]Board Certification Characteristics of Practicing Neuroradiologists [research-article]: BACKGROUND AND PURPOSE:Insight into the status of neuroradiology subspecialty certification across the United States could help to understand neuroradiologists' perceived value of subspecialty certification as well as guide efforts to optimize pathways for broader voluntary certification participation. Our aim was to assess board certification characteristics
- Identification of the Bleeding Point in Hemorrhagic Moyamoya Disease Using Fusion Images of Susceptibility-Weighted Imaging and Time-of-Flight MRA [ADULT BRAIN]Identification of the Bleeding Point in Hemorrhagic Moyamoya Disease Using Fusion Images of Susceptibility-Weighted Imaging and Time-of-Flight MRA [ADULT BRAIN]: BACKGROUND AND PURPOSE:The location of intracerebral hemorrhage in Moyamoya disease is a prognostic factor for rebleeding and the degree of preventive effects obtainable with bypass surgery. We evaluated whether the bleeding point and responsible vessel were detectable using fusion image
- Low-Profile Intra-Aneurysmal Flow Disruptor WEB 17 versus WEB Predecessor Systems for Treatment of Small Intracranial Aneurysms: Comparative Analysis of Procedural Safety and Feasibility [INTERVENTIONAL]Low-Profile Intra-Aneurysmal Flow Disruptor WEB 17 versus WEB Predecessor Systems for Treatment of Small Intracranial Aneurysms: Comparative Analysis of Procedural Safety and Feasibility [INTERVENTIONAL]: BACKGROUND AND PURPOSE:The Woven EndoBridge 17 has recently been introduced to the market for facilitated endovascular treatment of small bifurcation aneurysms (≤7 mm) with low-profile microcatheters. We compared the Woven EndoBridge 17 with its
- Chimeric Antigen Receptor T-Cell TherapyCAR T Cells: Engineering Patients’ Immune Cells to Treat Their CancersENLARGECo-stimulatory signaling domains have been added to newer generations of CAR T cells to improve their ability to produce more T cells after infusion and survive longer in the circulation.Credit: Brentjens R, et al. “Driving CAR T cells forward.” Nat Rev Clin Oncol. 2016 13, 370–383.For years, the foundations of cancer treatment were surgery, chemotherapy, and radiation t
- Carotid Artery Tortuosity Is Associated with Connective Tissue Diseases [EXTRACRANIAL VASCULAR]Carotid Artery Tortuosity Is Associated with Connective Tissue Diseases [EXTRACRANIAL VASCULAR]: BACKGROUND AND PURPOSE:There is a general assumption in the cerebrovascular literature that there is an association between carotid artery tortuosity and connective tissues disease; however, this has not been firmly established. The purpose of this study was to determine the prevalence of carotid artery tortuosity in patients with connective tissue di
- Comparison of [18F] FDG-PET/MRI and Clinical Findings for Assessment of Suspected Lumbar Facet Joint Pain: A Prospective Study to Characterize Candidate Nonanatomic Imaging Biomarkers and Potential Impact on Management [SPINE]Comparison of [18F] FDG-PET/MRI and Clinical Findings for Assessment of Suspected Lumbar Facet Joint Pain: A Prospective Study to Characterize Candidate Nonanatomic Imaging Biomarkers and Potential Impact on Management [SPINE]: BACKGROUND AND PURPOSE:Prior retrospective studies have suggested that both T2 hyperintensity and gadolinium enhancement on fat-suppressed MR imaging are associated with lumbar facet joint pain, but prospective evaluation
- Increased Diameters of the Internal Cerebral Veins and the Basal Veins of Rosenthal Are Associated with White Matter Hyperintensity Volume [ADULT BRAIN]Increased Diameters of the Internal Cerebral Veins and the Basal Veins of Rosenthal Are Associated with White Matter Hyperintensity Volume [ADULT BRAIN]: BACKGROUND AND PURPOSE:White matter hyperintensities on T2-weighted MR imaging are typical in older adults and have been linked to several poor health outcomes, including cognitive impairment and Alzheimer disease. The presence and severity of white matter hyperintensities have traditionally bee
- Cerebral Venous Thrombosis: MR Black-Blood Thrombus Imaging with Enhanced Blood Signal Suppression [ADULT BRAIN]Cerebral Venous Thrombosis: MR Black-Blood Thrombus Imaging with Enhanced Blood Signal Suppression [ADULT BRAIN]: BACKGROUND AND PURPOSE:The residual blood flow artifact is a critical confounder for MR black-blood thrombus imaging of cerebral venous sinus thrombosis. This study aimed to conduct a validation of a new MR black-blood thrombus imaging technique with enhanced blood signal suppression.MATERIALS AND METHODS:Twenty-six participants (13 v
- Empty Sella Is a Sign of Symptomatic Lateral Sinus Stenosis and Not Intracranial Hypertension [ADULT BRAIN]Empty Sella Is a Sign of Symptomatic Lateral Sinus Stenosis and Not Intracranial Hypertension [ADULT BRAIN]: BACKGROUND AND PURPOSE:Empty sella has been reported in patients with idiopathic intracranial hypertension and is thought to be a sign of elevation of intracranial pressure. However, it can also be found in patients with lateral sinus stenosis presenting with isolated pulsatile tinnitus without signs of intracranial hypertension. We hypoth
- FTIR Spectra Signatures Reveal Different Cellular Effects of EGFR Inhibitors on Non‐Small Cell Lung Cancer Cells (NSCLC)FTIR Spectra Signatures Reveal Different Cellular Effects of EGFR Inhibitors on Non‐Small Cell Lung Cancer Cells (NSCLC): AbstractATP‐analogue inhibitors, Gefitinib (Iressa) and Erlotinib (Tarceva), had been approved for advanced and metastatic NSCLC against tyrosine kinase domain of EGFR. Many techniques have been developed to better understand the drug mechanism which is multistep, time‐consuming, and expensive. Herein, we performed Fourier tra
- Effect of novel porphyrazine photosensitizers on normal and tumor brain cellsEffect of novel porphyrazine photosensitizers on normal and tumor brain cells: AbstractPhotodynamic therapy is a clinically approved procedure for targeting tumor cells. Though several different photosensitizers have been developed, there is still much demand for novel photosensitizers with improved properties. In this study we aim to characterize the accumulation, localization and dark cytotoxicity of the novel photosensitizers developed in‐hous
- Determination of Inclusion Depth in Ex vivo Animal Tissues using Surface Enhanced Deep Raman SpectroscopyDetermination of Inclusion Depth in Ex vivo Animal Tissues using Surface Enhanced Deep Raman Spectroscopy: This work presents recent developments in spatially offset (SO) and transmission Raman spectroscopy (TRS) for noninvasive detection and depth prediction of a single SERS inclusion located deep inside ex‐vivo biological tissues. The concept exploits the differential attenuation of Raman bands brought about by their different absorption due to
- Three‐Dimensional Intravital Imaging in Bone ResearchThree‐Dimensional Intravital Imaging in Bone Research: AbstractIntravital imaging has emerged as a novel and efficient tool for visualization of in situ dynamics of cellular behaviors and cell‐microenvironment interactions in live animals, based on desirable microscopy techniques featuring high resolutions, deep imaging and low phototoxicity. Intravital imaging, especially based on multi‐photon microscopy, has been used in bone research for dynam
- Evaluation of corneal epithelial thickness in glaucomatous patients using anterior‐segment optical coherence tomographyEvaluation of corneal epithelial thickness in glaucomatous patients using anterior‐segment optical coherence tomography: AbstractThe corneal epithelium represents one of the main structures that undergo degenerative alterations due to antiglaucomatous therapy. Chronic glaucoma therapy containing benzalkonium chloride induces epithelial cellular changes and inflammatory infiltration that in turn causes ocular surface changes resulting in ocular di
- Optical investigation of three‐dimensional human skin equivalents: A pilot studyOptical investigation of three‐dimensional human skin equivalents: A pilot study: AbstractHuman skin equivalents (HSEs) are three‐dimensional living models of human skin that are prepared in vitro by seeding cells onto an appropriate scaffold. They recreate the structure and biological behaviour of real skin, allowing the investigation of processes such as keratinocyte differentiation and interactions between the dermal and epidermal layers. Howe
- Optical investigation of three‐dimensional human skin equivalents: A pilot studyOptical investigation of three‐dimensional human skin equivalents: A pilot study: AbstractHuman skin equivalents (HSEs) are three‐dimensional living models of human skin that are prepared in vitro by seeding cells onto an appropriate scaffold. They recreate the structure and biological behaviour of real skin, allowing the investigation of processes such as keratinocyte differentiation and interactions between the dermal and epidermal layers. Howe
- Exploration research on the fusion of multimodal spectrum technology to improve performance of rapid diagnosis scheme for Thyroid DysfunctionExploration research on the fusion of multimodal spectrum technology to improve performance of rapid diagnosis scheme for Thyroid Dysfunction: ABSTRACTThe spectral fusion by Raman spectroscopy and Fourier infrared spectroscopy combined with pattern recognition algorithm is utilized to diagnose thyroid dysfunction serum, and finds the spectrum with the highest sensitivity to further advance diagnosis speed. Compared with the single infrared spectr
- Finite element study of controlling factors of anterior intrusion and torque during Temporary Skeletal Anchorage Device (TSAD) dependent en masse retraction without posterior appliances: Biocreative hybrid retractor (CH-retractor).Finite element study of controlling factors of anterior intrusion and torque during Temporary Skeletal Anchorage Device (TSAD) dependent en masse retraction without posterior appliances: Biocreative hybrid retractor (CH-retractor).: Related ArticlesFinite element study of controlling factors of anterior intrusion and torque during Temporary Skeletal Anchorage Device (TSAD) dependent en masse retraction without posterior appliances: Biocreative hy
- Treatment of dentigerous cysts with a modified Hawley plate in children: report of two cases with radiographic resultsTreatment of dentigerous cysts with a modified Hawley plate in children: report of two cases with radiographic results: Dentigerous cysts in young adults may compromise the natural evolution of the dentition and can be treated surgically or non-surgically. We report the minimally-invasive treatment of dentigerous cysts in two young patients using a modified Hawley plate to avoid traumatic injury to anatomical structures, with up to four years’ fo
- Re: adjuvant radiation in early oral cancers with isolated perineural invasionRe: adjuvant radiation in early oral cancers with isolated perineural invasion: We commend Rajappa et al for their recent study on the impact of perineural invasion,1 which has been discussed only scantily in the past. There has been a lack of prospective randomised studies either for or against adjuvant treatment in early oral cancers with singular adverse histopathological features (perineural invasion, lymphovascular invasion, the worst patter
- Clinicopathological features of peripheral ossifying fibroma in a series of 41 patientsClinicopathological features of peripheral ossifying fibroma in a series of 41 patients: Peripheral ossifying fibromas are benign mesenchymal lesions that usually arise in the anterior maxilla of young female patients. Histologically they consist of spindle cell proliferation with focal mineralisation. We reviewed 48 specimens from 41 patients and recorded the clinical data, sex, and age of the patients, site and size of the lesions, treatment, a
- Application of an open position splint integrated with a reference frame and registration markers for mandibular navigation surgeryApplication of an open position splint integrated with a reference frame and registration markers for mandibular navigation surgery: Navigation surgery plays an important role in modern craniomaxillofacial surgery, but it is difficult to apply navigation surgery to the mandible, due to its mobility. At present, headbands or headpins are widely used for fixation of the reference frame, and three strategies are generally used for the application of
- Impact of sarcopenia on postoperative surgical site infections in patients undergoing flap reconstruction for oral cancerImpact of sarcopenia on postoperative surgical site infections in patients undergoing flap reconstruction for oral cancer: Sarcopenia is characterized by progressive and generalized loss of skeletal muscle mass and strength. The aim of the study was to investigate the impact of skeletal muscle mass on surgical site infection (SSI) in flap reconstruction for defects after oral cancer resection. The subjects were a non-randomized, retrospective coh
- Independent risk factors for long-term skeletal relapse after mandibular advancement with bilateral sagittal split osteotomyIndependent risk factors for long-term skeletal relapse after mandibular advancement with bilateral sagittal split osteotomy: The purpose of this retrospective cohort study was to identify the independent risk factors for long-term skeletal relapse following mandibular advancement with bilateral sagittal split osteotomy. Univariate and multivariate linear regression analyses were performed including nine common risk factors for relapse as indepen
- Regulation of the autophagy-marker Sequestosome 1 in periodontal cells and tissues by biomechanical loadingRegulation of the autophagy-marker Sequestosome 1 in periodontal cells and tissues by biomechanical loading: AbstractPurposeOrthodontic treatment is based on the principle of force application to teeth and subsequently to the surrounding tissues and periodontal cells. Sequestosome 1 (SQSTM1) is a well-known marker for autophagy, which is an important cellular mechanism of adaptation to stress. The aim of this study was to analyze whether biomecha
- Use of a laser fluorescence device for the in vitro activity assessment of incipient caries lesionsUse of a laser fluorescence device for the in vitro activity assessment of incipient caries lesions: AbstractPurposeTo evaluate the progression of demineralization during orthodontic treatment, the assessment of lesion activity is important in addition to the detection of lesion extent. This study aimed to evaluate the ability of laser fluorescence measurements to differentiate between active and inactive initial lesions in vitro.MethodsIn all, 6
- Effect of different attachment geometries on the mechanical load exerted by PET‑G aligners during derotation of mandibular caninesEffect of different attachment geometries on the mechanical load exerted by PET‑G aligners during derotation of mandibular canines: AbstractAimDerotation of rounded teeth has proved difficult for aligners to achieve. In this study, we investigated the effect of aligner attachment geometry on the three-dimensional (3D) force and moment (F/M) values exerted during derotation of a mandibular canine.Materials and methodsThe experiment setup comprised
- Is Asymmetric Hearing Loss a Risk Factor for Vestibular Dysfunction? Lesson From Big Data Analysis Based on the Korean National Health and Nutrition SurveyIs Asymmetric Hearing Loss a Risk Factor for Vestibular Dysfunction? Lesson From Big Data Analysis Based on the Korean National Health and Nutrition Survey: Objective: The purpose of this study was to investigate whether asymmetric hearing loss affects vestibular function.Study Design: Retrospective cross-sectional study.Patients: Data from the 2010 Korean National Health and Nutrition Survey for adults aged 40 years or more were used.Interventio
- Otitis media: what is new?Otitis media: what is new?: Purpose of review To review the latest literature on otitis media diagnosis, guidelines, treatment, and pathophysiology.Recent findings Although otitis media remains one of the most common reasons for outpatient visits, antibiotic prescriptions, and surgery in the United States, little progress has been made in terms of developing novel treatments for the prevention and resolution of this condition, indicating the urge
- Pediatric hereditary angioedema: what the otolaryngologist should knowPediatric hereditary angioedema: what the otolaryngologist should know: Purpose of review To review pediatric hereditary angioedema for otolaryngologists, with emphasis on articles within the past 12–18 months.Recent findings Biologic therapies are accepted for adult hereditary angioedema (HAE), but have been studied less for pediatric HAE. Recent literature supports expanded use of biologic agents in pediatrics as acute treatment and prophylaxis
- In Vitro Characterization of Human, Mouse, and Zebrafish MCT8 OrthologuesIn Vitro Characterization of Human, Mouse, and Zebrafish MCT8 Orthologues: Thyroid, Ahead of Print. We use cookies to give you a better experience on liebertpub.com. By continuing to use our site, you are agreeing to the use of cookies as set in our Cookie Policy.OKMary Ann Leibert LogoABOUT USPUBLICATIONSAUTHORSLIBRARIANSOPEN ACCESSADVERTISINGCUSTOMThyroidAhead of PrintIn Vitro Characterization of Human, Mouse, and Zebrafish MCT8 OrthologuesStef
- Small-Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid DevelopmentSmall-Molecule Screening in Zebrafish Embryos Identifies Signaling Pathways Regulating Early Thyroid Development: Thyroid, Ahead of Print. Published Online:8 Oct 2019https://doi.org/10.1089/thy.2019.0122View ArticleToolsShareAbstractBackground: Defects in embryonic development of the thyroid gland are a major cause for congenital hypothyroidism in human newborns, but the underlying molecular mechanisms are still poorly understood. Organ developme
- Insurance Status Is Associated with Extent of Treatment for Patients with Papillary Thyroid CarcinomaInsurance Status Is Associated with Extent of Treatment for Patients with Papillary Thyroid Carcinoma: Thyroid, Ahead of Print.
- Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in MiceIncreased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice: Thyroid, Ahead of Print. AbstractBackground: Radioiodine refractory dedifferentiated thyroid cancer is a major clinical challenge. Anaplastic lymphoma kinase (ALK) mutations with increased ALK activity, especially fusion genes, have been suggested to promote thyroid carcinogenesis, leading to development of poorly differentiated thyroid carcin
- Extended Real-World Observation of Patients Treated with Sorafenib for Radioactive Iodine-Refractory Differentiated Thyroid Carcinoma and Impact of Lenvatinib Salvage Treatment: A Korean Multicenter StudyExtended Real-World Observation of Patients Treated with Sorafenib for Radioactive Iodine-Refractory Differentiated Thyroid Carcinoma and Impact of Lenvatinib Salvage Treatment: A Korean Multicenter Study: Thyroid, Ahead of Print. AbstractBackground: Treatment for patients with radioactive iodine (RAI)-refractory differentiated thyroid carcinoma (DTC) is challenging. Recently, two tyrosine kinase inhibitors (sorafenib and lenvatinib) have been ap
- Intraoperative and postanesthesia care unit fluid administration as risk factors for postoperative complications in patients with head and neck cancer undergoing free tissue transferIntraoperative and postanesthesia care unit fluid administration as risk factors for postoperative complications in patients with head and neck cancer undergoing free tissue transfer: AbstractBackgroundThis study aims to evaluate the impact of perioperative fluid administration, defined as fluid delivered intraoperatively and in the postanesthesia care unit, on postoperative outcomes.MethodsMedical records of 102 patients with oral cavity squamou
- Outcomes for elderly patients 75 years and older treated with curative intent radiotherapy for mucosal squamous cell carcinomas of the head and neckOutcomes for elderly patients 75 years and older treated with curative intent radiotherapy for mucosal squamous cell carcinomas of the head and neck: AbstractBackgroundElderly patients with mucosal squamous cell carcinomas of the head and neck (mHNSCC) represent a challenging clinical dilemma.MethodsA retrospective review was performed of patients ≥75 years, treated with curative‐intent radiotherapy for mHNSCC in two quaternary Sydney hospitals b
- Reproductive factors and thyroid cancer risk: Meta‐analysisReproductive factors and thyroid cancer risk: Meta‐analysis: AbstractBackgroundAssessed pooled risk on reproductive factors and oral contraceptives (OC) on thyroid cancer (TC) using published studies (1996‐2017).MethodsSummary odds ratio (OR) for case‐control studies (n = 10) and risk ratio (RR) for cohort studies (n = 9) was done.ResultsOR was 1.43 (95% CI: 1.16‐1.77) for age at menarche >14 years, 1.49 (95% CI: 1.19‐1.86) for parity >2, 1.38 (9
- Regenerating gene 1A single-nucleotide polymorphisms and nasopharyngeal carcinoma susceptibilityRegenerating gene 1A single-nucleotide polymorphisms and nasopharyngeal carcinoma susceptibilityThis comment refers to the article available online at https://doi.org/10.1007/s00405-019-05645-9.Dear, we read the publication on “Association of regenerating gene (*REG) 1A single-nucleotide polymorphisms and nasopharyngeal carcinoma (NPC) susceptibility in southern Chinese population” with a great interest and would like to share some ideas on this
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Τετάρτη 9 Οκτωβρίου 2019
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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00302841026182,
00306932607174,
alsfakia@gmail.com,
Anapafseos 5 Agios Nikolaos 72100 Crete Greece,
Medicine by Alexandros G. Sfakianakis
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