Nutrients, Vol. 11, Pages 2421: Anti-VEGF Signalling Mechanism in HUVECs by Melatonin, Serotonin, Hydroxytyrosol and Other Bioactive Compounds Nutrients doi: 10.3390/nu11102421 Authors: Ana B. Cerezo María Labrador Andrés Gutiérrez Ruth Hornedo-Ortega Ana M. Troncoso M. Carmen Garcia-Parrilla Angiogenesis drives evolution and destabilisation of atherosclerotic plaques and the growth and expansion of tumour cells. Vascular endothelial growth factor (VEGF) is the main endogenous...
Fri Oct 11, 2019 03:00
Pharmaceuticals, Vol. 12, Pages 153: Myristic Acid Coated Protein Immobilised Mesoporous Silica Particles as pH Induced Oral Delivery System for the Delivery of Biomolecules Pharmaceuticals doi: 10.3390/ph12040153 Authors: Vivek Trivedi Ruchir Bhomia John C Mitchell Solid core drug delivery systems (SCDDS) were prepared for the oral delivery of biomolecules using mesoporous silica as core, bovine haemoglobin (bHb) as model drug and supercritical fluid (SCF) processing as encapsulation...
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Pharmaceutics, Vol. 11, Pages 524: Enhanced Treatment Effects of Tilmicosin Against Staphylococcus aureus Cow Mastitis by Self-Assembly Sodium Alginate-Chitosan Nanogel Pharmaceutics doi: 10.3390/pharmaceutics11100524 Authors: Kaixiang Zhou Xiaofang Wang Dongmei Chen Yuanyuan Yuan Shuge Wang Chao Li Yuanyuan Yan Qianying Liu Liwei Shao Lingli Huang Zonghui Yuan Shuyu Xie The Staphylococcus aureus (S. aureus) cow mastitis causes great losses to the cow...
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Pharmaceutics, Vol. 11, Pages 523: Spray Drying of a Subcritical Extract Using Marrubium vulgare as a Method of Choice for Obtaining High Quality Powder Pharmaceutics doi: 10.3390/pharmaceutics11100523 Authors: Aleksandra Gavarić Jelena Vladić Rita Ambrus Stela Jokić Piroska Szabó-Révész Milan Tomić Marijana Blažić Senka Vidović White horehound (Marrubium vulgare L.), is a grey-leaved perennial herb, belonging to Lamiaceae family, distributed in Eurasia and northern...
Fri Oct 11, 2019 03:00
Pharmaceutics, Vol. 11, Pages 522: Enzyme-Loaded Gel Core Nanostructured Lipid Carriers to Improve Treatment of Lysosomal Storage Diseases: Formulation and In Vitro Cellular Studies of Elosulfase Alfa-Loaded Systems Pharmaceutics doi: 10.3390/pharmaceutics11100522 Authors: J. Víctor Álvarez Carolina Herrero Filgueira Alexandre de la Fuente González Cristóbal Colón Mejeras Andrés Beiras Iglesias Shunji Tomatsu José Blanco Méndez Asteria Luzardo Álvarez María Luz Couce...
Fri Oct 11, 2019 03:00
Pharmacy, Vol. 7, Pages 142: Advancing Pharmacist Collaborative Care within Academic Health Systems Pharmacy doi: 10.3390/pharmacy7040142 Authors: Awdishu Singh Saunders Yam Hirsch Lorentz Atayee Ma Tsunoda Namba Mnatzaganian Painter Watanabe Lee Daniels Morello Introduction: The scope of pharmacy practice has evolved over the last few decades to focus on the optimization of medication therapy. Despite this positive impact,...
Fri Oct 11, 2019 03:00
Plants, Vol. 8, Pages 409: Leaf Production and Expansion: A Generalized Response to Drought Stresses from Cells to Whole Leaf Biomass—A Case Study in the Tomato Compound Leaf Plants doi: 10.3390/plants8100409 Authors: Garance Koch Gaëlle Rolland Myriam Dauzat Alexis Bédiée Valentina Baldazzi Nadia Bertin Yann Guédon Christine Granier It is clearly established that there is not a unique response to soil water deficit but that there are as many responses as soil water...
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Plants, Vol. 8, Pages 408: Molecular Analyses of the Distribution and Function of Diazotrophic Rhizobia and Methanotrophs in the Tissues and Rhizosphere of Non-Leguminous Plants Plants doi: 10.3390/plants8100408 Authors: Yoneyama Terakado-Tonooka Bao Minamisawa Biological nitrogen fixation (BNF) by plants and its bacterial associations represent an important natural system for capturing atmospheric dinitrogen (N2) and processing it into a reactive form of nitrogen through...
Fri Oct 11, 2019 03:00
Religions, Vol. 10, Pages 569: Dialogue and Destabilization: An Index for Comparative Global Exemplarity Religions doi: 10.3390/rel10100569 Authors: Sara Ritchey This reflection derives from a discussion that took place at the 2018 “Comparative Hagiology” pre-conference workshop of the American Academy of Religion. The goal during that meeting was to articulate points of dialogue for the comparison of exemplary figures in various historic, geographic, and faith traditions....
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Safety, Vol. 5, Pages 68: Foundation Pit Collapse on 8 June 2019 in Nanning, China: A Brief Report Safety doi: 10.3390/safety5040068 Authors: Yie-Tong Chin Shui-Long Shen An-Nan Zhou Jun Chen This short communication reports on the recent incident of a foundation pit collapse at a construction site on 8 June 2019 in Nanning City of Guangxi Province, China. There were no injuries or casualties reported for this incident. This report presents the incident background, management...
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Smart Cities, Vol. 2, Pages 453-470: Urban Systems Design Case Study: Tokyo's Sumida Ward Smart Cities doi: 10.3390/smartcities2040028 Authors: Tobey Binder Yoshida Yamagata Meeting the needs of increasing environmental and systematic pressures in urban settlements requires the use of integrated and wholistic approaches. The Urban Systems Design (USD) Conceptual Framework joins the metric-based modeling of rationalized methods with human-driven goals to form a combined iterative...
Fri Oct 11, 2019 03:00
Social Sciences, Vol. 8, Pages 285: Exploring Gender Differences in Teacher–Student Interactions during an Adapted Robotics Program for Children with Disabilities Social Sciences doi: 10.3390/socsci8100285 Authors: Kendall Kolne Sally Lindsay We compared the interactions between teachers and children with disabilities enrolled in an adapted robotics program to examine potential gender differences in these interactions. We coded video recordings from instructional sections of the HB...
Fri Oct 11, 2019 03:00
Sports, Vol. 7, Pages 221: Effects of Different Combinations of Concentric and Eccentric Resistance Training Programs on Traditional and Alternative Hamstrings-to-Quadriceps Ratios Sports doi: 10.3390/sports7100221 Authors: Cassio V. Ruas Ronei S. Pinto Guy G. Haff Camila D. Lima Lee E. Brown Resistance training is often recommended for combined increases in traditional and alternative hamstrings-to-quadriceps (H:Q) ratios in order to reduce knee strength imbalance and associated...
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Sports, Vol. 7, Pages 220: Acute Metabolic Changes with Lower Leg-Positioned Wearable Resistances during Submaximal Running in Endurance-Trained Runners Sports doi: 10.3390/sports7100220 Authors: Field Gill Uthoff Plews The aim of this study was to determine the acute metabolic effects of different magnitudes of wearable resistance (WR) attached to the lower leg during submaximal running. Fifteen endurance-trained runners (37.8 ± 6.4 years; 1.77 ± 0.7...
Fri Oct 11, 2019 03:00
Toxins, Vol. 11, Pages 592: Dianthin and Its Potential in Targeted Tumor Therapies Toxins doi: 10.3390/toxins11100592 Authors: Hendrik Fuchs Dianthin enzymes belong to ribosome-inactivating proteins (RIPs) of type 1, i.e., they only consist of a catalytic domain and do not have a cell binding moiety. Dianthin-30 is very similar to saporin-S3 and saporin-S6, two RIPs often used to design targeted toxins for tumor therapy and already tested in some clinical trials. Nevertheless, dianthin...
Fri Oct 11, 2019 03:00
Toxins, Vol. 11, Pages 590: Fumonisin B1, B2 and B3 in Muscle and Liver of Broiler Chickens and Turkey Poults Fed with Diets Containing Fusariotoxins at the EU Maximum Tolerable Level Toxins doi: 10.3390/toxins11100590 Authors: Tardieu Travel Metayer Le Bourhis Guerre Although provisional maximum tolerable daily intake and recommended guidelines have been established for fumonisins (FB) in food, few data are available concerning levels of FB in edible animal tissues....
Fri Oct 11, 2019 03:00
Toxins, Vol. 11, Pages 591: Tyrosine Kinases in Helicobacter pylori Infections and Gastric Cancer Toxins doi: 10.3390/toxins11100591 Authors: Chichirau Diechler Posselt Wessler Helicobacter pylori (H. pylori) has been identified as a leading cause of gastric cancer, which is one of the most frequent and malignant types of tumor. It is characterized by its rapid progression, distant metastases, and resistance to conventional chemotherapy. A number of receptor tyrosine kinases...
Fri Oct 11, 2019 03:00
Toxins, Vol. 11, Pages 588: Optimization of SNAP-25 and VAMP-2 Cleavage by Botulinum Neurotoxin Serotypes A–F Employing Taguchi Design-of-Experiments Toxins doi: 10.3390/toxins11100588 Authors: Laura von Berg Daniel Stern Jasmin Weisemann Andreas Rummel Martin Bernhard Dorner Brigitte Gertrud Dorner The detection of catalytically active botulinum neurotoxins (BoNTs) can be achieved by monitoring the enzymatic cleavage of soluble NSF (N-ethylmaleimide-sensitive-factor)...
Fri Oct 11, 2019 03:00
Toxins, Vol. 11, Pages 587: A Multiplex Analysis of Potentially Toxic Cyanobacteria in Lake Winnipeg during the 2013 Bloom Season Toxins doi: 10.3390/toxins11100587 Authors: Katelyn M. McKindles Paul V. Zimba Alexander S. Chiu Susan B. Watson Danielle B. Gutierrez Judy Westrick Hedy Kling Timothy W. Davis Lake Winnipeg (Manitoba, Canada), the world’s 12th largest lake by area, is host to yearly cyanobacterial harmful algal blooms (cHABs) dominated by Aphanizomenon...
Fri Oct 11, 2019 03:00
Toxins, Vol. 11, Pages 589: Association between Serum Indoxyl Sulfate Levels and Endothelial Function in Non-Dialysis Chronic Kidney Disease Toxins doi: 10.3390/toxins11100589 Authors: Chih-Hsien Wang Yu-Hsien Lai Chiu-Huang Kuo Yu-Li Lin Jen-Pi Tsai Bang-Gee Hsu Indoxyl sulfate (IS), a product metabolized from tryptophan, is negatively correlated with renal function and cardiovascular diseases in patients with chronic kidney disease (CKD). We investigated the association...
Fri Oct 11, 2019 03:00
Toxins, Vol. 11, Pages 586: Promise and the Pharmacological Mechanism of Botulinum Toxin A in Chronic Prostatitis Syndrome Toxins doi: 10.3390/toxins11100586 Authors: Chien-Hsu Chen Pradeep Tyagi Yao-Chi Chuang Chronic prostatitis/chronic pelvic pain syndrome (CP/ CPPS) has a negative impact on the quality of life, and its etiology still remains unknown. Although many treatment protocols have been evaluated in CP/CPPS, the outcomes have usually been disappointing. Botulinum neurotoxin...
Fri Oct 11, 2019 03:00
Vaccines, Vol. 7, Pages 146: Evaluation of Pneumococcal Surface Protein A as a Vaccine Antigen against Secondary Streptococcus pneumoniae Challenge during Influenza A Infection Vaccines doi: 10.3390/vaccines7040146 Authors: Sean Roberts Clare M. Williams Sharon L. Salmon Jesse L. Bonin Dennis W. Metzger Yoichi Furuya Secondary bacterial pneumonia is responsible for significant morbidity and mortality during seasonal and pandemic influenza. Due to the unpredictability of...
Fri Oct 11, 2019 03:00
Vaccines, Vol. 7, Pages 147: A Retrospective Cohort Study of Safety Outcomes in New Zealand Infants Exposed to Tdap Vaccine in Utero Vaccines doi: 10.3390/vaccines7040147 Authors: Helen Petousis-Harris Yannan Jiang Lennex Yu Donna Watson Tony Walls Nikki Turner Anna S. Howe Jennifer B. Griffin We aimed to evaluate the safety of maternal Tdap; thus, we assessed health events by examining the difference in birth and hospital-related outcomes of infants with and without...
Fri Oct 11, 2019 03:00
Viruses, Vol. 11, Pages 940: Nosocomial Transmission of Emerging Viruses via Aerosol-Generating Medical Procedures Viruses doi: 10.3390/v11100940 Authors: Seth D. Judson Vincent J. Munster Recent nosocomial transmission events of emerging and re-emerging viruses, including Ebola virus, Middle East respiratory syndrome coronavirus, Nipah virus, and Crimean–Congo hemorrhagic fever orthonairovirus, have highlighted the risk of nosocomial transmission of emerging viruses in...
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Viruses, Vol. 11, Pages 939: The XIth International Symposium on Thysanoptera and Tospoviruses Co-sponsored by Yunnan Academy of Agricultural Sciences and Nanjing Agricultural University in Kunming, China 2019 Viruses doi: 10.3390/v11100939 Authors: Xiaorong Tao Zhongkai Zhang The XIth International Symposium on Thysanoptera and Tospoviruses co-hosted by the Yunnan Academy of Agricultural Sciences, and Nanjing Agricultural University was held from September 21–25 in Kunming,...
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Viruses, Vol. 11, Pages 937: Methyl-Beta-Cyclodextrin-Induced Macropinocytosis Results in Increased Infection of Sf21 Cells by Bombyx Mori Nucleopolyhedrovirus Viruses doi: 10.3390/v11100937 Authors: Huang Li Fan liu Boadi Shen Hao Bombyx mori nucleopolyhedrovirus (BmNPV) is closely related to Autographa californica multiple nucleopolyhedrovirus (AcMNPV) with over ~93% amino acid sequence identity. However, their host ranges are essentially nonoverlapping. The...
Fri Oct 11, 2019 03:00
Viruses, Vol. 11, Pages 935: Quantitative Microscopy Reveals Stepwise Alteration of Chromatin Structure during Herpesvirus Infection Viruses doi: 10.3390/v11100935 Authors: Aho Mäntylä Ekman Hakanen Mattola Chen Weinhardt Ruokolainen Sodeik Larabell Vihinen-Ranta During lytic herpes simplex virus 1 (HSV-1) infection, the expansion of the viral replication compartments leads to an enrichment of the host chromatin in the peripheral nucleoplasm....
Fri Oct 11, 2019 03:00
Viruses, Vol. 11, Pages 938: High Fidelity Deep Sequencing Reveals No Effect of ATM, ATR, and DNA-PK Cellular DNA Damage Response Pathways on Adenovirus Mutation Rate Viruses doi: 10.3390/v11100938 Authors: Risso-Ballester Sanjuán Most DNA viruses exhibit relatively low rates of spontaneous mutation. However, the molecular mechanisms underlying DNA virus genetic stability remain unclear. In principle, mutation rates should not depend solely on polymerase fidelity, but also on factors...
Fri Oct 11, 2019 03:00
Viruses, Vol. 11, Pages 936: Cross-Protection of Inactivated Rabies Vaccines for Veterinary Use against Bat Lyssaviruses Occurring in Europe Viruses doi: 10.3390/v11100936 Authors: Servat Wasniewski Cliquet Human rabies vaccines have been shown to induce partial protection against members of phylogroup I bat lyssaviruses. Here, we investigated the capacity of a widely used rabies inactivated vaccine (Rabisin, Boehringer-Ingelheim) for veterinary use to cross-protect mice experimentally...
Fri Oct 11, 2019 03:00
Viruses, Vol. 11, Pages 934: Structural Pattern Differences in Unbranched Rod-like RNA of Hepatitis Delta Virus affect RNA Editing Viruses doi: 10.3390/v11100934 Authors: Hsu Juang Kuo Li Iang Lin Yeh Chao Hepatitis delta virus (HDV) RNA forms an unbranched rod-like structure and complexes with the delta antigen (HDAg). Host ADAR1-catalyzed RNA editing at the amber/W site of the small HDAg leads to the production of the large HDAg, which inhibits replication...
Fri Oct 11, 2019 03:00
Viruses, Vol. 11, Pages 933: A Bivalent Live-Attenuated Vaccine for the Prevention of Equine Influenza Virus Viruses doi: 10.3390/v11100933 Authors: Pilar Blanco-Lobo Laura Rodriguez Stephanie Reedy Fatai S. Oladunni Aitor Nogales Pablo R. Murcia Thomas M. Chambers Luis Martinez-Sobrido Vaccination remains the most effective approach for preventing and controlling equine influenza virus (EIV) in horses. However, the ongoing evolution of EIV has increased the genetic...
Fri Oct 11, 2019 03:00
Water, Vol. 11, Pages 2114: Design Equation for Stirring Fluid by a Stream Pump in a Circulating Tank Water doi: 10.3390/w11102114 Authors: Jerzy Sawicki Paweł Wielgat Piotr Zima A circulating tank is a very useful theoretical scheme for many fluid-flow objects in several branches of engineering. The motion of the fluid in such objects can be induced in different ways. A stream pump provides an especially interesting possibility; however, the quantitative description of such devices...
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Water, Vol. 11, Pages 2113: Rainfall Thresholds for Prediction of Landslides in Idukki, India: An Empirical Approach Water doi: 10.3390/w11102113 Authors: Minu Treesa Abraham Deekshith Pothuraju Neelima Satyam Idukki is a South Indian district in the state of Kerala, which is highly susceptible to landslides. This hilly area which is a hub of a wide variety of flora and fauna, has been suffering from slope stability issues due to heavy rainfall. A well-established landslide early...
Fri Oct 11, 2019 03:00
Water, Vol. 11, Pages 2112: Bridging Terrestrial and Marine Geoheritage: Assessing Geosites in Portofino Natural Park (Italy) Water doi: 10.3390/w11102112 Authors: Paola Coratza Vittoria Vandelli Lara Fiorentini Guido Paliaga Francesco Faccini Interest in geoheritage research has grown over the past 25 years and several countries have issued laws to encourage improvement and conservation. Investigations on geosites are prevalently carried out on land environments, although...
Fri Oct 11, 2019 03:00
Water, Vol. 11, Pages 2111: Electrospun Nylon 6,6/ZIF-8 Nanofiber Membrane for Produced Water Filtration Water doi: 10.3390/w11102111 Authors: Nur Syakinah Abd Halim Mohd Dzul Hakim Wirzal Muhammad Roil Bilad Nik Abdul Hadi Md Nordin Zulfan Adi Putra Abdull Rahim Mohd Yusoff Thanitporn Narkkun Kajornsak Faungnawakij This study develops electrospun nylon 6,6 nanofiber membrane (NFM), incorporating zeolitic imidazolate framework-8 (ZIF-8) as the additive for produced...
Fri Oct 11, 2019 03:00
Water, Vol. 11, Pages 2110: Comparing Meteorological Data Sets in the Evaluation of Climate Change Impact on Hydrological Indicators: A Case Study on a Mexican Basin Water doi: 10.3390/w11102110 Authors: Juan Alberto Velázquez-Zapata This study evaluates the choice of the meteorological data set in the simulation of the streamflow of a Mexican basin, in the bias correction of climate simulations, and in the climate change impact on hydrological indicators. The selected meteorological...
Fri Oct 11, 2019 03:00
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