Anusheel Munshi, Tharmarnadar Ganesh, Bidhu K MohantiIndian Journal of Cancer 2019 56(4):359-363 The history and current status of a biomedical discipline in a country or region provide important health system indicators. During the last one hundred years, radiotherapy has established its position as a vital specialty in cancer management. It has proved to be one of the most cost effective ways of treating cancer providing both radical and palliative treatments depending on patient stage and...
Fri Oct 11, 2019 00:00
Waseem Abbas, Ranga Raju RaoIndian Journal of Cancer 2019 56(4):293-296Adjuvant ovarian suppression, on addition to chemotherapy, reduces the risk of breast cancer in pre-menopausal women after surgery and adjuvant hormonal therapy. Suppression of Ovarian Function Trial (SOFT) and Tamoxifen and Exemestane Trial (TEXT) showed greater benefit with exemestane in high risk females in comparison to Tamoxifen. Ovarian Function Suppression (OFS) and exemestane became the standard of care, with 30% patients...
Fri Oct 11, 2019 00:00
Ramachandran Krishna Kumar, Arvind Krishnamurthy, Gomadam Kuppusamy Rangarajan, Nagarathinam Anandi, Namasivayam ParvathnathanIndian Journal of Cancer 2019 56(4):379-380
Fri Oct 11, 2019 00:00
Jarin Noronha, Ashwin deSouza, Prachi Patil, Shaesta Mehta, Reena Engineer, Vikas Ostwal, Anant Ramaswamy, Suman K Ankathi, Mukta Ramadwar, Avanish SaklaniIndian Journal of Cancer 2019 56(4):297-301 AIM: To define the patterns of disease presentation, treatment strategies, and outcomes for patients with colon cancer at a tertiary referral center in India over 1 year period. MATERIALS AND METHODS: This is a retrospective analysis of a prospectively maintained database. All consecutive patients...
Fri Oct 11, 2019 00:00
Manoj Kalita, Manigreeva KrishnatreyaIndian Journal of Cancer 2019 56(4):371-372
Fri Oct 11, 2019 00:00
Roopa R Paulose, Divya A Ail, Shital Biradar, Anu Vasudevan, KR SundaramIndian Journal of Cancer 2019 56(4):302-308 BACKGROUND: Microsatellite instability (MSI) accounts for 15–20% of colorectal cancer (CRC) and is considered to have favorable stage-adjusted prognosis compared to Microsatellite stable (MSS) CRCs. Determination of MSI in stage II CRC is important for management decisions regarding adjuvant chemotherapy administration. The aim of this study was to determine the prognostic and predictive...
Fri Oct 11, 2019 00:00
Atsushi Marumo, Taro Mizuki, Sakae TanosakiIndian Journal of Cancer 2019 56(4):354-355 The prognosis of atypical chronic myeloid leukemia (aCML) patients is poor, but some patients with a suitable donor can be treated with allogeneic hematopoietic stem cell transplantation (HSCT). However, many of these patients cannot be treated with HSCT due to their age. The effectiveness of decitabine was recently indicated in case reports; however, the effectiveness of azacitidine (AZA) has not yet been...
Fri Oct 11, 2019 00:00
Nitty Skariah Mathews, Dipti Masih, Rohin Mittal, Benjamin Perakath, Dhananjayan Sakthi, Grace Rebekah, Rekha Pai, Anna B PulimoodIndian Journal of Cancer 2019 56(4):309-314 CONTEXT: The incidence of colorectal cancers (CRCs) in young Indian patients is higher than the international average. CRCs in young patients are commonly of mucinous type and show microsatellite instability (MSI). AIMS: To ascertain the MSI status of mucinous CRCs in patients ≤40 years of age by molecular testing and to...
Fri Oct 11, 2019 00:00
John D CoyneIndian Journal of Cancer 2019 56(4):368-369
Fri Oct 11, 2019 00:00
Naresh Somani, Pawan Agarwal, Harish Singhal, Abhishek K Singh, Abhilasha Sinha, Rajshri Somani, Jia Agarwal, Shaurya DugarIndian Journal of Cancer 2019 56(4):315-319 Purpose: Limited treatment options are available for patients with advanced non-small cell lung cancer (NSCLC) after failure of first-line platinum-based chemotherapy. The treatment of recurrent advanced NSCLC progressed with the arrival of nivolumab and other immunotherapeutic agents. Our single-center prospective study aimed to...
Fri Oct 11, 2019 00:00
Basawantrao Malipatil, Adarsh Palleti, Namita Sinha Verma, Sanjeev V KattiIndian Journal of Cancer 2019 56(4):374-375
Fri Oct 11, 2019 00:00
Shwetha Seetharam, Priyakumari Thankamony, Kaduveettil Gopinathan Gopakumar, K M Jagathnath KrishnaIndian Journal of Cancer 2019 56(4):320-324 BACKGROUND: Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is a well-known adverse effect of vincristine (VCR). Literature suggests that Asians are predisposed to develop SIADH following VCR administration. However, data regarding the occurrence of SIADH in children with malignancy are limited. This study aims to analyze the incidence,...
Fri Oct 11, 2019 00:00
Jacob McKnight, Ken FlemingIndian Journal of Cancer 2019 56(4):291-292
Fri Oct 11, 2019 00:00
Prateek V Jain, Rajeev Sharan, Kapila Manikantan, Gautam Biswas, Soumendranath Ray, Pattatheyil ArunIndian Journal of Cancer 2019 56(4):325-329 BACKGROUND: Papillary carcinoma of thyroid (PTC) is usually indolent with good prognosis and excellent long-term survival. However, PTC sometimes presents itself in unusual situations, posing diagnostic and therapeutic challenges. Owing to paucity of data, there is lack of consensus as to what treatment should be prescribed in patients with loco-regional...
Fri Oct 11, 2019 00:00
Jeyashanth Riju, Shaji ThomasIndian Journal of Cancer 2019 56(4):356-358 Papillary carcinoma of thyroid (PCT) commonly shows metastasis to central and lateral cervical compartment neck nodes. Submental nodes are rarely involved by PCT. Thus, its management is not clear. We report two young men who presented with submental nodal metastasis from PCT. Both underwent total thyroidectomy with central compartment neck dissection and modified radical neck dissection (MRND). Probable factors which might...
Fri Oct 11, 2019 00:00
Bindhu Joseph, Rekha V Kumar, G Champaka, Ashok Shenoy, KS Sabitha, V Lokesh, C Ramesh, CR VijayIndian Journal of Cancer 2019 56(4):330-334 BACKGROUND: Recent advances in radiation technology has allowed to significantly reduce toxicity and improve the efficacy of radical radiotherapy in head and neck and oral squamous cell cancers. Insights into molecular biology of carcinogenesis has opened a window for identifying aggressive clinical situations that may benefit with larger clinical target volume...
Fri Oct 11, 2019 00:00
Shirish N KavadiIndian Journal of Cancer 2019 56(4):364-367 This note presents a brief account of the ideas and efforts of V.R. Khanolkar in the period 1952–1962 to develop the Indian Cancer Research Centre into a “center of excellence”. Khanolkar, who is recognized as a pioneer in cancer research in India, focused on developing multidisciplinary medical research and mentored and trained young medical researchers. He sought and received aid from the Rockefeller Foundation, which was keen to support...
Fri Oct 11, 2019 00:00
Anuj Verma, Santosh Menon, Bharat Rekhi, Trupti Pai, Amita Maheshwari, Jaya Ghosh, Sudeep Gupta, Kedar DeodharIndian Journal of Cancer 2019 56(4):335-340 Background: Endometrial stromal sarcoma (ESS) is a common uterine mesenchymal malignancy. According to World Health Organisation (WHO) 2014 classification, ESSs are further subdivided into low-grade ESS (LGESS) and high-grade ESS (HGESS). HGESS is defined by the presence of YWHAE gene rearrangement and has a poorer prognosis compared to LGESS....
Fri Oct 11, 2019 00:00
Rashmi Sudhir, Veeriah K Chaudhary, Faiq Ahmed, K VVN RajuIndian Journal of Cancer 2019 56(4):370-371
Fri Oct 11, 2019 00:00
Vladan Popovic, Neda Milosavljevic, Marija Zivkovic Radojevic, Radisa H Vojinovic, Nikola Nedovic, Slobodanka Mitrovic, Jasmina Nedovic, Aleksandar TomasevicIndian Journal of Cancer 2019 56(4):341-347 INTRODUCTION: To define indications for adjuvant radiotherapy in patients with endometrial cancer, the risk groups have been established according to clinical and pathological prognostic factors. The purpose was to determine precise criteria for adjuvant radiotherapy and identify patients with increased...
Fri Oct 11, 2019 00:00
Ilavarasi Vanidassane, Ajay Gogia, Saumyaranjan MallickIndian Journal of Cancer 2019 56(4):373-374
Fri Oct 11, 2019 00:00
HS Darling, S Jayalakshmi, Pradeep JaiswalIndian Journal of Cancer 2019 56(4):348-349
Fri Oct 11, 2019 00:00
Sergio Pineiro-Donis, Manuel Torres-López, Abel García-García, Xavier Marichalar-Mendía, Pilar Gándara-Vila, Alejandro-Ismael Lorenzo-Pouso, Andrés Blanco-Carrión, Mario Pérez-SáyansIndian Journal of Cancer 2019 56(4):375-378
Fri Oct 11, 2019 00:00
Sandeep Vijayan, Chirag Jain, Monappa Aroor Naik, Sharath Kumar RaoIndian Journal of Cancer 2019 56(4):350-353 Osteoid osteoma of foot and ankle account for ten percent of benign bone tumors and commonly involve the talus and metatarsals. Its occurrence in calcaneus is extremely rare and can mimic ankle instability, subtalar arthritis, osteochondritis or plantar fasciitis leading to delay in diagnosis. We present the case of a 17 year old boy with periarticular osteoid osteoma in the calcaneum,...
Fri Oct 11, 2019 00:00
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