Abstract We aimed to make a meta-analysis regarding the effect of bariatric surgery on female sexual function. PubMed, EMBASE, and CENTRAL were searched from database inception through August 2019. Articles were eligible for inclusion if they examined the effect of bariatric surgery on obese women’s sexual function assessed by the Female Sexual Functioning Index (FSFI) or/and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12). Twenty articles were included...
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Related ArticlesCochlear implantation in the era of genomic medicine. Cochlear Implants Int. 2019 Oct 24;:1-4 Authors: Molina-Ramirez LP, Bruce IA, Black GCM PMID: 31648626 [PubMed - as supplied by publisher]
Related ArticlesShort and long term preservation of hearing thresholds corrected for natural hearing loss in cochlear implant recipients using a straight electrode. Cochlear Implants Int. 2019 Oct 24;:1-7 Authors: Snels CWM, Huinck WJ, Swinnen FKR, Dhooge I, Mylanus EAM Abstract Objectives: The aim of this study is to investigate short and long term residual hearing preservation (HP), corrected for the natural progress of hearing loss, in cochlear implant...
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Related ArticlesGross Pathology of Routine Pediatric Tonsillectomy Specimens: Optimizing the Value of Patient Care. Otolaryngol Head Neck Surg. 2019 02;160(2):339-342 Authors: Hobbs EA, Hanson JA, Nicholas RG, Johnson BR, Hawley KA Abstract OBJECTIVE: This investigation seeks to evaluate the effect of gross pathologic analysis on our management of patients undergoing routine tonsillectomy and to evaluate charges and reimbursement. STUDY DESIGN:...
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Related ArticlesA comparative assessment of three planes of implant placement in breast augmentation: A Bayesian analysis. J Plast Reconstr Aesthet Surg. 2019 Sep 24;: Authors: Shen Z, Chen X, Sun J, Chiu C, Yu Y, Lin X, Zhang Z, Xu J Abstract BACKGROUND: Techniques based on three planes of implant placement, including the subglandular (SG), subpectoral (SP), and subfascial (SF) planes are used for breast augmentation. The placement that offers the greatest...
Related ArticlesPlastic surgery research: Current activities and future scope. J Plast Reconstr Aesthet Surg. 2019 Sep 27;: Authors: Zargaran D, Zargaran A PMID: 31653595 [PubMed - as supplied by publisher]
Related ArticlesRetrospective cohort-based comparison of intraoperative liposomal bupivacaine versus bupivacaine for donor site iliac crest analgesia during alveolar bone grafting. J Plast Reconstr Aesthet Surg. 2019 Oct 02;: Authors: Patel RA, Jablonka EM, Rustad KC, Pridgen BC, Sorice-Virk SS, Borrelli MR, Khosla RK, Lorenz HP, Momeni A, Wan DC Abstract INTRODUCTION: Bone grafting of alveolar clefts is routinely performed with cancellous bone harvested...
Related ArticlesA prospective comparison of breast sensibility after reduction mammoplasty: Superior versus superomedial pedicle. J Plast Reconstr Aesthet Surg. 2019 Oct 01;: Authors: Silhol T, Chaouat M, Harizi R, Lambert J, Noel W, Mimoun M, Boccara D Abstract BACKGROUND: Breast sensitivity is a significant issue in preoperative consultation prior to reduction mammoplasty. Although a range of techniques is used, recovery of sensation is usually evaluated...
Related ArticlesThe width of pedicle included in reverse dorsoradial flap of the thumb: As wide as possible? J Plast Reconstr Aesthet Surg. 2019 Oct 11;: Authors: Qin H, Kong J, Xu L, Wang H, Ma N, Xia J PMID: 31648960 [PubMed - as supplied by publisher]
Related ArticlesForehead deformities after tissue expansion: Retrospective analysis and recommendations. J Plast Reconstr Aesthet Surg. 2019 Oct 02;: Authors: Qiu Y, Qiao C, Yang J, Jin Y, Chen H, Lin X Abstract BACKGROUND: Tissue expanders can lead to bone deformity as well as bone resorption. Not all changes in the cranial bone can be completely normalised after tissue expander extraction. This study aimed to investigate the potential factors for persistent...
Related ArticlesUse of CT in a standing position for preoperative evaluation in abdominal incisional hernia: A pilot study. J Plast Reconstr Aesthet Surg. 2019 Oct 01;: Authors: Sakamoto Y, Yamada M, Yamada Y, Yokoyama Y, Kishi K, Jinzaki M PMID: 31648958 [PubMed - as supplied by publisher]
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Related ArticlesDegree of technical difficulty of thyroidectomy for autoimmune thyroid disease. Head Neck. 2019 Oct 25;: Authors: Saadi R, Brandt A, Kim Y, Cottrill E, Saunders B, Schaefer E, Goldenberg D Abstract BACKGROUND: Our goal was to elucidate the differences in degree of technical difficulty of thyroidectomy in patients with autoimmune thyroid diseases. METHODS: Charts of adult patients who had undergone thyroidectomy were reviewed....
Related ArticlesThe relations of dosimetric parameters with long-term outcomes and late toxicities in advanced T-stage nasopharyngeal carcinoma with IMRT. Head Neck. 2019 Oct 24;: Authors: Gou X, Duan B, Shi H, Qin L, Xiao J, Chen N Abstract BACKGROUND: Balancing the dose requirements between targets and normal tissue is a challenge in radiation of nasopharyngeal carcinoma (NPC). The purpose of this study is to evaluate the dosimetric parameters and...
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AbstractBackgroundThe GLOBAL LEADERS (GLOBAL LEADERS: A Clinical Study Comparing Two Forms of Anti-platelet Therapy After Stent Implantation) study randomly assigned 15,991 patients undergoing percutaneous coronary intervention to 1-month dual antiplatelet therapy (DAPT) followed by 23-month ticagrelor monotherapy or conventional 12-month DAPT followed by 12-month aspirin. Apart from Q-wave myocardial infarction (MI), all study endpoints were analyzed as investigator reported. ObjectivesThis was...
AbstractUnderserved minorities make up a disproportionately small subset of patients in the United States undergoing transcatheter and surgical aortic valve replacement for aortic stenosis. The reasons for these treatment gaps include differences in disease prevalence and patient, health care system, and disease-related factors. This has major implications not only for minority patients, but also for other groups who face similar challenges in accessing state-of-the-art care for structural heart...
AbstractBackgroundBenefits of multiarterial versus single-arterial coronary bypass grafting (CABG) are debated. ObjectivesThis study sought to compare long-term survival, morbidity, and graft patency after multiarterial versus single-arterial CABG. MethodsMandatory clinical registries linked with discharge databases were used to identify baseline and operative characteristics and outcomes of 42,714 patients undergoing CABG from 2005 through 2012. Patients with single-vessel disease, without arterial...
AbstractBackgroundAlthough procedure-related deaths during index admission following catheter ablation of AF have been reported to be low, adverse outcomes can occur after discharge. There are limited data on mortality early after AF ablation. ObjectivesThis study aimed to identify rates, trends, and predictors of early mortality post-atrial fibrillation (AF) ablation. MethodsUsing the all-payer, nationally representative Nationwide Readmissions Database, we evaluated 60,203 admissions of patients...
AbstractIn the contemporary era, nearly 85% of children with congenital heart disease will reach adulthood. Despite optimal medical and surgical treatment, many will experience a progressive decline in cardiopulmonary function leading to advanced heart failure. These patients present unique anatomic and physiological challenges to the care team, and unlike adults with acquired heart disease who progress to severe heart failure, advanced treatment options such as mechanical circulatory support and...
When it Comes to the Mortality Rates of Catheter Ablation of Atrial Fibrillation, Experience Matters
AbstractBackgroundDirect current cardioversion (DCCV) is a common rhythm control strategy in patients with symptomatic atrial fibrillation or flutter. There is no long-term data regarding the safety of DCCV in patients with endocardial left atrial appendage occlusion (LAAO) devices. ObjectivesThe purpose of this study was to assess the feasibility and safety of DCCV in patients with an LAAO device. MethodsThis multicenter retrospective study included 148 patients with an LAAO device who underwent...
AbstractBackgroundThe assessment of coronary flow velocity reserve (CFVR) in left anterior descending coronary artery (LAD) expands the risk stratification potential of stress echocardiography (SE) based on stress-induced regional wall motion abnormalities (RWMA). ObjectivesThe purpose of this study was to assess the feasibility and functional correlates of CFVR. MethodsThis prospective, observational, multicenter study initially screened 3,410 patients (2,061 [60%] male; age 63 ± 11 years; ejection...
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59 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/10/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesSalivary Pepsin as an Intrinsic Marker for Diagnosis of Sub-types of Gastroesophageal Reflux Disease and Gastroesophageal Reflux Disease-related Disorders. J Neurogastroenterol Motil. 2019 Oct 25;: Authors: Wang YJ, Lang XQ, Wu D, He YQ, Lan CH, Xiao X, Wang B, Zou DW, Wu JM, Zhao YB, Dettmar PW, Chen DF, Yang M Abstract Background/Aims: To determine the value of salivary pepsin in discriminating sub-types of gastroesophageal refluxdisease...
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Related ArticlesFeasibility of Hyaluronate Carboxymethylcellulose-Based Bioresorbable Membrane in Two-Staged Pancreatojejunostomy. World J Surg. 2019 Oct 25;: Authors: Yamazaki S, Takayama T, Mitsuka Y, Yoshida N, Yoshida N, Shimamoto N, Higaki T Abstract BACKGROUND: Two-staged pancreatoduodenectomy with exteriorization of pancreatic juice is a safe procedure for high-risk patients. However, two-staged pancreatoduodenectomy requires complex re-laparotomy...
Related ArticlesBile Duct Stones Predict a Requirement for Cholecystectomy in Older Patients. World J Surg. 2019 Oct 25;: Authors: Matsui Y, Hirooka S, Sakaguchi T, Kotsuka M, Yamaki S, Yamamoto T, Kosaka H, Satoi S, Sekimoto M Abstract BACKGROUND: The requirement for elective cholecystectomy in older patients is unclear. To determine predictors for requiring elective cholecystectomy in older patients, a prospective cohort study was performed. ...
Related ArticlesWaiting Too Long: The Contribution of Delayed Surgical Access to Pediatric Disease Burden in Somaliland. World J Surg. 2019 Oct 25;: Authors: Smith ER, Concepcion TL, Shrime M, Niemeier K, Mohamed M, Dahir S, Ismail EA, Poenaru D, Rice HE, Global Initiative for Children’s Surgery Abstract BACKGROUND: Delayed access to surgical care for congenital conditions in low- and middle-income countries is associated with increased risk of death...
Related ArticlesCurative Surgery Improves Survival for Colorectal Cancer in Rural Kenya. World J Surg. 2019 Oct 24;: Authors: Parker RK, Mwachiro MM, Ranketi SS, Mogambi FC, Topazian HM, White RE Abstract BACKGROUND/AIMS: Colorectal cancer (CRC) is increasing in low- and middle-income countries. Surgical care is essential for the treatment. Many patients do not have access to curative surgery for colorectal cancer in rural Kenya. To better understand...
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66 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "J BUON"[jour] These pubmed results were generated on 2019/10/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Nature Immunology, Published online: 28 October 2019; doi:10.1038/s41590-019-0541-8Manipulating the mitochondrial morphology of exhausted tumor-derived NK cells restores their metabolic fitness and function.
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Related ArticlesExploration of medicinal plants as sources of novel anticandidal drugs. Curr Top Med Chem. 2019 Oct 25;: Authors: Kumar A, Khan F, Saikia D Abstract BACKGROUND: Human infections associated with skin and mucosal surfaces, mainly in tropical and sub-tropical part of the world. During the last decade, there have been increasing numbers of cases of fungal infections in immunocompromised patients, coupled with increase in number of incidences...
Related ArticlesNew and Promising Chemotherapeutics for Emerging Infections Involving Drug-Resistant Non-albicans Candida Species. Curr Top Med Chem. 2019 Oct 25;: Authors: Silva LN, de Mello TP, de Souza Ramos L, Branquinha MH, Dos Santos ALS Abstract Fungal infections are a veritable public health problem worldwide. The increasing number of patient populations at risk (e.g. transplanted individuals, cancer patients and HIV-infected people) as well...
Related ArticlesThe Chemistry of Drugs to Treat Candida albicans. Curr Top Med Chem. 2019 Oct 25;: Authors: Ortiz A, Sansinenea E Abstract BACKGROUND: Candida species are in various parts of the human body as commensals. However, they can cause local mucosal infections and sometimes, systemic infections in which Candida species can spread to all major organs and colonize these. OBJECTIVE: For the effective treatment of the mucosal infections...
Related ArticlesMolecules and Metabolites from Natural Products as Inhibitors of Biofilm in Candida spp. pathogens. Curr Top Med Chem. 2019 Oct 25;: Authors: K Singla R, K Dubey A Abstract BACKGROUND: Biofilm is a critical virulence factor associated with the strains of Candida spp. pathogens as it confers significant resistance to the pathogen against antifungal drugs. METHODS: A systematic review of the literature was undertaken by focusing...
Related ArticlesRecent Advances in Ginsenosides as Potential Therapeutics Against Breast Cancer. Curr Top Med Chem. 2019 Oct 17;: Authors: Guo YH, Kuruganti R, Gao Y Abstract The dried root of ginseng (Panax ginseng C. A. Meyer or Panax quinquefolius L.) is a traditional Chinese medicine widely used to manage cancer symptoms and chemotherapy side effects in Asia. The anti-cancer efficacy of ginseng is attributed mainly to the presence of saponins, which...
Related ArticlesImpacts of pseudo amino acid components and 5-steps rule to proteomics and proteome analysis. Curr Top Med Chem. 2019 Oct 17;: Authors: Chou KC Abstract Stimulated by the 5-steps rule during the last decade or so, the computational proteomics has achieved remarkable progresses in the following three areas: (1) protein structural class prediction; (2) protein subcellular location prediction; (3) post-translational modification (PTM) site...
Related ArticlesA Possible Modulation Mechanism of Intramolecular and Intermolecular Interactions for NCAM Polysialylation and Cell Migration. Curr Top Med Chem. 2019 Oct 17;: Authors: Lu B, Liu XH, Lia SM, Lu ZL, Chen D, A Troy Ii F, Huang RB, Zhou GP Abstract Polysialic acid (polySia) is a novel glycan that posttranslationally modifies neural cell adhesion molecules (NCAMs) in mammalian cells. Up-regulation of polySia-NCAM expression or NCAM polysialylation...
Related ArticlesSynthesis of coumarin derivatives as versatile scaffolds for GSK-3β enzyme inhibition. Curr Top Med Chem. 2019 Oct 18;: Authors: S Franciscoa C, L Javarini C, de S Barcelos I, A B Morais P, de Paula H, de S Borges W, Neto ÁC, Lacerda V Abstract BACKGROUND: Glycogen synthase kinase-3 (GSK-3) is involved in the phosphorylation and inactivation of glycogen synthase. GSK-3 inhibitors have been associated with a variety of diseases, including...
Related ArticlesFunctionalization Silver nanoparticles loaded with paclitaxel induced A549 cells apoptosis through ROS-Mediated signaling pathways. Curr Top Med Chem. 2019 Oct 18;: Authors: Zou J, Zhu B, Li Y Abstract Currently, paclitaxel (PTX) is one of the most important and effective anticancer drug for treatment of human cancer. Unfortunately it is limited by low solubility and severe adverse effects in clinical use. Silver nanoparticles (AgNPs)...
Related ArticlesNovel Quinolinyl-pyrrolo[3,4-d]pyrimidine-2,5-dione Derivatives Against Chloroquine-resistant Plasmodium falciparum. Curr Top Med Chem. 2019 Oct 18;: Authors: Rogerio KR, Graebin CS, Helena Pinto Domingues L, Oliveira LS, de Souza Fernandes da Silva V, Daniel-Ribeiro CT, J M Carvalho L, Boechat N Abstract AIMS: Obtaining new quinolinyl-pyrrolopyrimidinone derivatives against chloroquine-resistant Plasmodium falciparum. <p> Background:...
Related ArticlesBiological production of (S)-acetoin: a state-of-the-art review. Curr Top Med Chem. 2019 Oct 18;: Authors: Xie NZ, Li JX, Huang RB Abstract Acetoin is an important four-carbon compound that has many applications in foods, chemical synthesis, cosmetics, cigarettes, soaps, and detergents. Its stereoisomer (S)-acetoin, a high-value chiral compound, can also be used to synthesize optically active drugs, which could enhance targeting properties...
Related ArticlesCyclodextrin Inclusion of Medicinal Compounds for Enhancement of their Physicochemical and Biopharmaceutical Properties. Curr Top Med Chem. 2019 Oct 17;: Authors: R Caira M Abstract Owing to their wide structural diversity and unique complexing properties, cyclodextrins (CDs) find manifold applications in drug discovery and development. The focus of this mini-review is on their uses as 'enabling excipients' both in the context of early...
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Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition that primarily affects the motor system and shares many features with frontotemporal dementia (FTD). Evidence suggests that ALS is a ‘dying-back’ disease, with peripheral denervation and axonal degeneration occurring before loss of motor neuron cell bodies. Distal to a nerve injury, a similar pattern of axonal degeneration can be seen, which is mediated by an active axon destruction mechanism...
Abstract Glycogen storage disorder type III (GSDIII), or debranching enzyme (GDE) deficiency, is a rare metabolic disorder characterized by variable liver, cardiac, and skeletal muscle involvement. GSDIII manifests with liver symptoms in infancy and muscle involvement during early adulthood. Muscle biopsy is mainly performed in patients diagnosed in adulthood, as routine diagnosis relies on blood or liver GDE analysis, followed by AGL gene sequencing. The GSDIII mouse model recapitulate...
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