Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveOsteoporosis can lead to bone fragility and an increased risk of bone fracture with resultant high morbidity and mortality. Living alone has been associated with various mental and physical health problems. However, the risk of osteoporosis among individuals with different living conditions and changing living conditions is unclear. We examined the risk of osteoporosis in different living conditions over a 3-year...
Tue Aug 11, 2020 08:19
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study was performed to analyze the correlation between perioperative hidden blood loss (HBL) and the general condition of patients undergoing transforaminal lumbar interbody fusion (TLIF).MethodsWe retrospectively analyzed patients who underwent TLIF from July 2017 to July 2019 in our hospital. Sex, age, body mass index, underlying diseases, American Society of Anesthesiologists classification, coagulation function,...
Mon Aug 10, 2020 13:41
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThoracic endovascular aortic repair (TEVAR) is considered the mini-invasive treatment of choice for patients with Stanford type B aortic dissection (TBAD). This study aimed to investigate the clinical outcomes and quality of life (QoL) in patients with acute and subacute TBAD after TEVAR.MethodsFrom January 2014 until July 2016, 22 acute patients (Group A) and 18 subacute patients received TEVAR (Group B), and 13...
Mon Aug 10, 2020 09:09
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo compare the efficacy of dexmedetomidine and magnesium sulfate as an adjuvant to local anesthetics in spinal anesthesia.MethodsA search of PubMed, Medline, Embase, the Cochrane Library, and Google Scholar was performed. Randomized controlled trials comparing the efficacy of dexmedetomidine and magnesium sulfate as a local anesthetic adjuvant in spinal anesthesia were identified. The primary outcome was sensory...
Mon Aug 10, 2020 08:59
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo evaluate the efficacy and safety of the combination of pegylated liposomal doxorubicin and docetaxel as neoadjuvant therapy for breast cancer (BC) in patients with axillary lymph node metastasis.MethodsIn this single-arm study, 91 patients with clinical stage IIA–IIIc breast cancer received six cycles of pegylated liposomal doxorubicin plus docetaxel as neoadjuvant chemotherapy (NAC). Trastuzumab was allowed for...
Mon Aug 10, 2020 08:59
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study investigated the synergistic repair effects of Prontosan hydrogel and carbon photon therapy in a rat full-thickness wound model.MethodsThe wavelength distribution of the photon source was determined. Dehydration of the Prontosan hydrogel and fibroblast viability were analyzed following exposure to different durations of light exposure at different distances from the source. Indexes of wound healing in...
Mon Aug 10, 2020 08:53
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveStudies have demonstrated that tetrandrine reverses multidrug resistance (MDR) in animal models or cell lines derived from multiple cancer types. We examined the potential MDR reversal activity of tetrandrine in a multidrug-resistant variant of a human laryngeal cancer Hep-2 cell line and explored potential mechanisms involved.MethodsWe developed the multidrug-resistant variant cell line (Hep-2/v) by exposing Hep-2...
Mon Aug 10, 2020 08:53
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveWe aimed to investigate factors associated with nonadherence to antihypertensive medication among middle-aged Taiwanese adults with hypertension.MethodsWe used data from the 2009 Taiwan National Health Interview Survey (NHIS) to identify adults age 40 to 65 years with hypertension. We used logistic regression analyses to investigate factors associated with nonadherence to antihypertensive medication.ResultsA total...
Mon Aug 10, 2020 08:52
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo investigate Acacia honey from different altitudes regarding total phenols and flavonoids, laser-induced fluorescence (LIF) spectra and anticancer activity against human cancer cell lines.MethodsAnticancer activity was investigated using sulforhodamine B cytotoxicity assays in the following human cancer cell lines: HCT116 (colon); MCF7 (breast), and HepG2 (liver). Total phenols and flavonoids were measured using...
Mon Aug 10, 2020 08:52
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveObservational studies have shown that circulating vitamin D (VitD) deficiency is associated with atherogenic lipid patterns among polycystic ovary syndrome (PCOS) patients. However, interventional studies have shown inconsistent results. The aim of this meta-analysis was to investigate how VitD supplementation influences lipid indices in PCOS patients.MethodsThe authors searched four electronic databases through...
Mon Aug 10, 2020 08:21
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study aimed to investigate application of the urine albumin-to-creatinine ratio (ACR), serum beta 2-microglobulin (β2-MG), and cystatin C as risk markers in a cohort of women with polycystic ovary syndrome (PCOS) for the incidence of gestational diabetes mellitus (GDM).MethodsIn this cross-sectional study, we analyzed 312 pregnant women with PCOS and classified them as those with and without GDM. For all participants,...
Mon Aug 10, 2020 08:20
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveLong noncoding (lnc)RNAs regulate multiple biological processes including cancer. Oral squamous cell carcinoma (OSCC) is a common malignancy with poor prognosis. We aimed to identify the function of lncRNA HOXA10 antisense RNA (HOXA10-AS) and its clinical significance.MethodsWe used differential expression analysis to identify aberrantly expressed lncRNAs associated with OSCC. We identified key genes related to HOXA10-AS...
Mon Aug 10, 2020 08:19
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThe perfusion index (PI) is usually used to assess peripheral perfusion, which can be influenced by the cardiac index (CI). CI monitoring is often needed during the treatment of patients with shock. We investigated the relationship between changes in the PI (ΔPI) and changes in the CI (ΔCI) in patients with septic shock.MethodsThis retrospective study included patients with septic shock who underwent pulse-induced...
Mon Aug 10, 2020 08:19
Journal of International Medical Research, Volume 48, Issue 8, August 2020. We herein report two cases of paradoxical carbon dioxide (CO2) embolism during laparoscopic nephrectomy and hepatic left lateral lobectomy without evidence of a right-to-left shunt or obvious rupture of blood vessels. Transesophageal echocardiography detected paradoxical CO2 embolism before the end-tidal CO2 partial pressure (PETCO2) dropped from baseline. The pneumoperitoneum was reduced or stopped immediately after detection...
Mon Aug 10, 2020 08:18
Journal of International Medical Research, Volume 48, Issue 8, August 2020. The sudden outbreak of severe acute respiratory syndrome coronavirus 2 pneumonia posed a significant challenge to medical professionals because treatment of critically ill patients requires the efforts of a multidisciplinary team. To highlight this principle, we examined acute kidney injury (AKI) in IgA-dominant infection-associated glomerulonephritis (GN) and menstrual toxic shock syndrome (mTSS). Both GN and mTSS are rare...
Mon Aug 10, 2020 08:18
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study aimed to compare energy and macronutrient intake, birth weight, and anthropometric parameters (mid-upper arm circumference or tricipital skin-fold thickness) between women who had adequate and excessive gestational weight gain (GWG) during pregnancy.MethodsWe studied 115 pregnant women and divided them according to GWG into two groups: adequate GWG (n = 49) and excessive GWG (n = 66). We assessed the medical...
Mon Aug 10, 2020 08:18
Journal of International Medical Research, Volume 48, Issue 8, August 2020. This report describes the presence of Stenotrophomonas maltophilia endophthalmitis after phacoemulsification in a 66-year-old woman. The patient presented with ocular redness and pain, as well as hypopyon in the anterior chamber and reduction of visual acuity to hand motion. Intraocular fluid examination revealed a lipopolysaccharide level of >2.5, which suggested bacterial endophthalmitis. The patient was promptly treated...
Mon Aug 10, 2020 08:18
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo evaluate the efficacy and safety of the addition of local infiltration analgesia (LIA) to adductor canal block (ACB) for pain control after primary total knee arthroplasty (TKA).MethodsTwo reviewers independently searched for potentially relevant published studies using electronic databases, including PubMed® (1966 to June 2019), Embase® (1974 to June 2019) and Web of Science (1990 to June 2019). The results were...
Mon Aug 10, 2020 07:52
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveInflammation and viral infections can induce significant changes in lipid metabolism. Hypertriglyceridemia (HTG) often occurs secondary to obesity, which is an independent risk factor for influenza virus infection. However, the inflammatory risk factors contributing to HTG in patients with severe influenza have yet to be elucidated.Materials and methodsPlasma and bronchoalveolar lavage fluid (BALF) samples were collected...
Mon Aug 10, 2020 07:50
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study aimed to investigate serum matrix metalloproteinase (MMP)-2 and MMP-9 levels in patients with papillary thyroid carcinoma (PTC).MethodsForty-one patients with PTC undergoing ultrasound-guided radiofrequency ablation (RFA) and 56 controls were included. Serum MMP-2 and MMP-9 levels were determined by enzyme-linked immunosorbent assay before and after surgery. Potential affecting factors were evaluated by...
Mon Aug 10, 2020 06:25
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