Co-registration of Intravascular Ultrasound with Angiographic Imaging for Carotid Artery Disease. World Neurosurg. 2020 Aug 07;: Authors: Kerolus MG, Joshi KC, Johnson AK, Furlan AB, Mangubat EZ, Theessen H, Schafer S, Lopes DK Abstract OBJECTIVE: Intravascular ultrasound (IVUS) provides endoluminal views and cross-sectional images of carotid arteries but lacks overview of vascular territory provided by angiography. Co-registration of IVUS...
Tue Aug 11, 2020 13:24
Immunoglobulin G4-related Hypertrophic Pachymeningitis of the Spine: A Case Report and Systematic Review of the Literature. World Neurosurg. 2020 Aug 07;: Authors: Sbeih I, Darwazeh R, Shehadeh M, Al-Kanash R, Abu-Farsakh H, Sbeih A Abstract BACKGROUND: Spinal immunoglobulin G4-related hypertrophic pachymeningitis (IgG4-HP) is a rare disease. Little information is known regarding the diagnosis, management and prognosis of patients with spinal...
Tue Aug 11, 2020 13:24
Primary intracranial angiomatoid fibrous histiocytoma: Two case reports and literature review. World Neurosurg. 2020 Aug 07;: Authors: Abdulqader SB, Altuhaini K, Tallab R, AlTurkistani A, Alhussinan M, Alghamdi S, Al Saidi K, Almalki S, Alshakweer W, Alotaibi FE Abstract BACKGROUND: Angiomatoid fibrous histiocytoma (AFH) is a rare, fibrohistiocytic, soft-tissue neoplasm. Intracranial AFH is extremely rare. Herein, we present two pediatric...
Tue Aug 11, 2020 13:24
Pipeline embolization in patients with posterior circulation subarachnoid hemorrhages: Is Takotsubo cardiomyopathy a limiting factor? World Neurosurg. 2020 Aug 07;: Authors: Baker C, Grandhi R, Griessenauer CJ, Dmytriw AA, Kapadia A, Yang VXD, Ghorbani M, Chen K, Aziz-Sultan MA, Rinaldo L, Lanzino G, Brinjikji W, Taussky P Abstract BACKGROUND: Hemorrhagic vascular lesions in the posterior cerebral circulation such as ruptured aneurysms and...
Tue Aug 11, 2020 13:24
The perioperative management of subarachnoid hemorrhage during Coronavirus disease 2019 pandemic in CHINA: case series report. World Neurosurg. 2020 Aug 07;: Authors: Zeng M, Li S, Li M, Yan X, Li R, Dong J, Zhang Y, Miao Z, Wang S, Peng Y, Han R Abstract BACKGROUND: For most of the international community out of the epicenter, Coronavirus disease 2019 (COVID-19) containment is normalizing, and daily medical practice is paralleling with preventing...
Tue Aug 11, 2020 13:24
The Impact of Body Mass Index on Outcomes of Mechanical Thrombectomy in Acute Ischemic Stroke. World Neurosurg. 2020 Aug 07;: Authors: Chen SH, McCarthy D, Saini V, Brunet MC, Peterson EC, Yavagal D, Starke RM Abstract BACKGROUND: Obesity is an established risk factor for the development of acute ischemic stroke, but its impact on clinical outcomes after acute ischemic stroke remains controversial. In this study, we evaluate the association...
Tue Aug 11, 2020 13:24
Case Volumes and Perioperative COVID-19 Incidence in Neurosurgical Patients During a Pandemic: Experiences at Two Tertiary Care Centers in Washington, DC. World Neurosurg. 2020 Aug 07;: Authors: Dowlati E, Zhou T, Sarpong K, Pivazyan G, Briscoe J, Fayed I, Mualem W, Black J, Kalhorn CG, Nair MN, Felbaum DR Abstract OBJECTIVE: The true incidence of perioperative COVID-19 is not well elucidated in the neurosurgical literature. We aim to review...
Tue Aug 11, 2020 13:24
Impact of Fenestrated Pedicle Screws with Cement Augmentation in Osteoporotic Patients Undergoing Spinal Fusion. World Neurosurg. 2020 Aug 06;: Authors: Saadeh YS, Swong KN, Yee TJ, Strong MJ, Kashlan ON, Szerlip NJ, Oppenlander ME, Park P Abstract OBJECTIVE: Osteoporosis is a well-known risk factor for instrumentation failure and subsequent pseudoarthrosis after spinal fusion. This systematic review analyzed the biomechanical properties, clinical...
Tue Aug 11, 2020 13:24
Histone deacetylases inhibitors as new potential drugs against Leishmania braziliensis, the main causative agent of New World Tegumentary Leishmaniasis. Biochem Pharmacol. 2020 Aug 07;:114191 Authors: Ângelo de Souza L, Silva E Bastos M, de Melo Agripino J, Souza Onofre T, Fanny Apaza Calla L, Heimburg T, Ghazy E, Bayer T, Hugo Ferraz da Silva V, Dutra Ribeiro P, Licursi de Oliveira L, Costa Bressan G, Rogéria de Almeida Lamêgo M, Silva-Júnior A, de Souza...
Tue Aug 11, 2020 13:18
Synthesis and biological evaluation of substituted pyrrolidines and pyrroles as potential anticancer agents. Arch Pharm (Weinheim). 2020 Aug 09;:e2000136 Authors: Ji J, Sajjad F, You Q, Xing D, Fan H, Reddy AGK, Hu W, Dong S Abstract A series of polysubstituted pyrrolidines obtained via ruthenium-catalyzed cascade cyclization of diazo pyruvates and anilines as well as their corresponding pyrrole analogs obtained via dehydration were evaluated...
Tue Aug 11, 2020 13:18
Different effects of tryptophan 2,3-dioxygenase inhibition on SK-Mel-28 and HCT-8 cancer cell lines.
Different effects of tryptophan 2,3-dioxygenase inhibition on SK-Mel-28 and HCT-8 cancer cell lines. J Cancer Res Clin Oncol. 2020 Aug 10;: Authors: Paccosi S, Cecchi M, Silvano A, Fabbri S, Parenti A Abstract PURPOSE: Indoleamine 2,3-dioxygenase-1 (IDO1) and more recently, tryptophan 2,3-dioxygenase (TDO), are tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. IDO1 is more expressed than TDO in many tumours including...
Tue Aug 11, 2020 13:18
Repurposing antidepressant sertraline as a pharmacological drug to target prostate cancer stem cells: dual activation of apoptosis and autophagy signaling by deregulating redox balance. Am J Cancer Res. 2020;10(7):2043-2065 Authors: Chinnapaka S, Bakthavachalam V, Munirathinam G Abstract Cancer stem cells play a major role in tumor initiation, progression, and tumor relapse of prostate cancer (PCa). Recent studies suggest that Translationally...
Tue Aug 11, 2020 13:18
High expression of NSUN5 promotes cell proliferation via cell cycle regulation in colorectal cancer.
High expression of NSUN5 promotes cell proliferation via cell cycle regulation in colorectal cancer. Am J Transl Res. 2020;12(7):3858-3870 Authors: Jiang Z, Li S, Han MJ, Hu GM, Cheng P Abstract NSUN5, a gene encodes a cytosine-5 RNA methyltransferase, is rarely mentioned in cancers. Our study is the first one to evaluate the role of NSUN5 in the progression of colorectal cancer. Data from TCGA was used to show the different expression...
Tue Aug 11, 2020 13:18
Ganoderic Acid D Protects Human Amniotic Mesenchymal Stem Cells against Oxidative Stress-Induced Senescence through the PERK/NRF2 Signaling Pathway. Oxid Med Cell Longev. 2020;2020:8291413 Authors: Xu Y, Yuan H, Luo Y, Zhao YJ, Xiao JH Abstract Aging is an important risk factor in the occurrence of many chronic diseases. Senescence and exhaustion of adult stem cells are considered as a hallmark of aging in organisms. In this study, a senescent...
Tue Aug 11, 2020 13:18
Chinese Propolis Inhibits the Proliferation of Human Gastric Cancer Cells by Inducing Apoptosis and Cell Cycle Arrest. Evid Based Complement Alternat Med. 2020;2020:2743058 Authors: Jiang XS, Xie HQ, Li CG, You MM, Zheng YF, Li GQ, Chen X, Zhang CP, Hu FL Abstract Special Chinese propolis sourced from the Changbai Mountains (CBMP) in Northeast China is rich in specific flavonoids and phenolic acids and its bioactivity has not been reported....
Tue Aug 11, 2020 13:18
The combination of Biochanin A and SB590885 potentiates the inhibition of tumour progression in hepatocellular carcinoma. Cancer Cell Int. 2020;20:371 Authors: Xiao Y, Gong Q, Wang W, Liu F, Kong Q, Pan F, Zhang X, Yu C, Hu S, Fan F, Li S, Liu Y Abstract Background: Hepatocellular carcinoma (HCC) is the most aggressive and frequently diagnosed malignancy of the liver. Despite aggressive therapy, life expectancy of many patients in these...
Tue Aug 11, 2020 13:18
Circular RNA hsa_circ_0000517 modulates hepatocellular carcinoma advancement via the miR-326/SMAD6 axis. Cancer Cell Int. 2020;20:360 Authors: He S, Guo Z, Kang Q, Wang X, Han X Abstract Background: Hepatocellular carcinoma (HCC) is the most common malignant heterogeneous disease in primary liver tumors. Circular RNA hsa_circ_0000517 (hsa_circ_0000517) is connected with HCC prognosis. Nevertheless, there are few studies on the role and...
Tue Aug 11, 2020 13:18
An investigative study of antitumor properties of a novel thiazolo[4,5-d]pyrimidine small molecule revealing superior antitumor activity with CDK1 selectivity and potent pro-apoptotic properties. Bioorg Med Chem. 2020 Sep 01;28(17):115633 Authors: Mohamed SH, Elgiushy HR, Taha H, Hammad SF, Abou-Taleb NA, A M Abouzid K, Al-Sawaf H, Hassan Z Abstract New thiazolo[4,5-d]pyrimidine analogues were synthesized and biologically assessed in-vitro...
Tue Aug 11, 2020 13:18
MiR-23a induced the activation of CDC42/PAK1 pathway and cell cycle arrest in human cov434 cells by targeting FGD4. J Ovarian Res. 2020 Aug 09;13(1):90 Authors: Lin J, Huang H, Lin L, Li W, Huang J Abstract BACKGROUND: MiRNAs play important roles in the development of ovarian cancer, activation of primitive follicles, follicular development, oocyte maturation and ovulation. In the present study, we investigated the specific role of miR-23a...
Tue Aug 11, 2020 13:18
Wnt-induced, TRP53-mediated Cell Cycle Arrest of Precursors Underlies Interstitial Cell of Cajal Depletion during Aging. Cell Mol Gastroenterol Hepatol. 2020 Aug 06;: Authors: Hayashi Y, Asuzu DT, Bardsley MR, Gajdos GB, Kvasha SM, Linden DR, Nagy RA, Saravanaperumal SA, Syed SA, Toyomasu Y, Yan H, Chini EN, Gibbons SJ, Kellogg TA, Khazaie K, Kuro-O M, Espindola Netto JM, Singh MP, Tidball JG, Wehling-Henricks M, Farrugia G, Ordog T Abstract ...
Tue Aug 11, 2020 13:18
Related Articles High expression of PSF1 promotes drug resistance and cell cycle transit in leukemia cells. Cancer Sci. 2020 Jul;111(7):2400-2412 Authors: Hsieh HY, Jia W, Jin ZC, Kidoya H, Takakura N Abstract Escape of cancer cells from chemotherapy is a problem in the management of cancer patients. Research on chemotherapy resistance has mainly focused on the heterogeneity of cancer cells, multiple gene mutations, and quiescence of malignant...
Tue Aug 11, 2020 13:18
Epilepsy, anti-seizure medication, intellectual disability and challenging behaviour - Everyone's business, no one's priority. Seizure. 2020 Jul 23;81:111-116 Authors: Kinney MO, Chester V, Tromans S, Alexander RT, Angus-Leppan H, Bagary M, Cock H, Devapriam J, Hassiotis A, Mula M, Reuber M, Ring H, Roy A, Scheepers M, Shankar R Abstract PURPOSE: People with Intellectual Disability (ID) and epilepsy are more likely to experience psychiatric...
Tue Aug 11, 2020 16:17
Stereotactic MRI-guided laser interstitial thermal therapy for extratemporal lobe epilepsy. Epilepsia. 2020 Aug 10;: Authors: Gupta K, Cabaniss B, Kheder A, Gedela S, Koch P, Hewitt KC, Alwaki A, Rich C, Ramesha S, Hu R, Drane DL, Gross RE, Willie JT Abstract OBJECTIVE: Magnetic resonance imaging (MRI)-guided laser interstitial thermal therapy (MRg-LITT) is an alternative to open epilepsy surgery. We assess safety and effectiveness of MRg-LITT...
Tue Aug 11, 2020 16:17
A novel composition of two heterozygous GFM1 mutations in a Chinese child with epilepsy and mental retardation. Brain Behav. 2020 Aug 09;:e01791 Authors: You C, Xu N, Qiu S, Li Y, Xu L, Li X, Yang L Abstract INTRODUCTION: G elongation factor mitochondrial 1 (GFM1) encodes one of the mitochondrial translation elongation factors. GFM1 variants were reported to be associated with neurological diseases and liver diseases in a few cases. Here, we...
Tue Aug 11, 2020 16:17
Turning a Drug Target into a Drug Candidate: A New Paradigm for Neurological Drug Discovery? Bioessays. 2020 Aug 09;:e2000011 Authors: Buckingham SD, Mann HJ, Hearnden OK, Sattelle DB Abstract The conventional paradigm for developing new treatments for disease mainly involves either the discovery of new drug targets, or finding new, improved drugs for old targets. However, an ion channel found only in invertebrates offers the potential of a...
Tue Aug 11, 2020 16:17
Precision medicine and therapies of the future. Epilepsia. 2020 Jul 24;: Authors: Sisodiya SM Abstract Precision medicine in the epilepsies has gathered much attention, especially with gene discovery pushing forward new understanding of disease biology. Several targeted treatments are emerging, some with considerable sophistication and individual-level tailoring. There have been rare achievements in improving short-term outcomes in a few very...
Tue Aug 11, 2020 16:17
Sleep Quality and Associated Factors among Peoples with Epilepsy Who Have a Follow-Up at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia, 2019: An Institutional Based Cross-Sectional Study. Psychiatry J. 2020;2020:1402712 Authors: Adem K, Kassew T, Birhanu A, Abate A Abstract Background: Sleep is an active cyclic biological phenomenon and necessary for survival. Individuals who suffer from sleep disturbance are less productive, decreased...
Tue Aug 11, 2020 16:17
An atypical case of febrile infection-related epilepsy syndrome following acute encephalitis: impact of physiotherapy in regaining locomotor abilities in a patient with neuroregression. Pan Afr Med J. 2020;36:101 Authors: Goyal C, Naqvi WM, Sahu A Abstract Encephalitis refers to inflammation of the brain parenchyma. It is potentially life-threatening with the highest incidence and severity in younger children. Febrile infection-related epilepsy...
Tue Aug 11, 2020 16:17
Aqueous Root Bark Extract of Daniellia oliveri (Hutch. & Dalz.) (Fabaceae) Protects Neurons against Diazepam-Induced Amnesia in Mice. Evid Based Complement Alternat Med. 2020;2020:7815348 Authors: Beppe GJ, Kenko Djoumessie LB, Keugong Wado E, Ngatanko Abaïssou HH, Nkwingwa BK, Damo Kamda JL, Nhouma RR, Foyet HS Abstract Daniellia oliveri (DO) is a traditional medicinal plant used for the treatment of diseases such as inflammation, schizophrenia,...
Tue Aug 11, 2020 16:17
Ketogenic diet as a metabolic treatment for mental illness. Curr Opin Endocrinol Diabetes Obes. 2020 Aug 06;: Authors: Norwitz NG, Dalai SS, Palmer CM Abstract PURPOSE OF REVIEW: Ketogenic diets, which have been used to treat drug-refractory paediatric epilepsy for over 100 years, are becoming increasingly popular for the treatment of other neurological conditions, including mental illnesses. We aim to explain how ketogenic diets can improve...
Tue Aug 11, 2020 16:17
Therapeutic effects of children with refractory epilepsy after vagus nerve stimulation in Taiwan. Pediatr Neonatol. 2020 Jul 22;: Authors: Li ST, Chiu NC, Hung KL, Ho CS, Kuo YT, Wu WH, VNS TCNS Abstract BACKGROUND: Vagus nerve stimulation (VNS) is used as an add-on treatment for epilepsy. This study aimed to use Taiwanese nationwide registry data to analyze the therapeutic effects of VNS in children with refractory epilepsy (RE) and try to...
Tue Aug 11, 2020 16:17
Perampanel as first add-on choice on the treatment of mesial temporal lobe epilepsy: an observational real-life study. Neurol Sci. 2020 Aug 09;: Authors: Labate A, Fortunato F, Giugno A, Martino I, Caligiuri ME, Gambardella A Abstract PURPOSE: To evaluate the efficacy of perampanel (PER) in patients with a diagnosis of mesial temporal lobe epilepsy (MTLE) taking PER as first add-on option due to inefficacy of first antiepileptic drug (AED),...
Tue Aug 11, 2020 16:17
Neuropsychological findings related to the presence of pre-surgical comorbid depression in Latin-American patients with mesial temporal lobe epilepsy and hippocampal sclerosis. Seizure. 2020 Aug 03;81:96-103 Authors: Figueiredo NSV, Cavalcanti MM, Gaça LB, Noffs MHDS, Sousa AVM, Alonso NB, Mazetto L, de Araújo Filho GM, Yacubian EMT, Guilhoto LM Abstract PURPOSE: To evaluate the neuropsychological findings related to the presence of pre-surgical...
Tue Aug 11, 2020 16:17
Testing an early online intervention for the treatment of disturbed sleep during the COVID-19 pandemic (Sleep COVID-19): structured summary of a study protocol for a randomised controlled trial. Trials. 2020 Aug 08;21(1):704 Authors: Elder GJ, Alfonso-Miller P, Atkinson WCM, Santhi N, Ellis JG Abstract OBJECTIVES: The primary aim of the present study is to examine the efficacy of an online intervention for poor sleep in the context of an ongoing...
Tue Aug 11, 2020 16:17
Related Articles Taurine and GABA neurotransmitter receptors, a relationship with therapeutic potential? Expert Rev Neurother. 2019 04;19(4):289-291 Authors: Ochoa-de la Paz L, Zenteno E, Gulias-Cañizo R, Quiroz-Mercado H Abstract Taurine is a β-amino acid present in high concentrations in different areas of the mammalian central nervous system (CNS). It participates in different physiological processes such as osmoregulation, signal transduction,...
Tue Aug 11, 2020 16:17
Osteolytic metastasis in breast cancer: effective prevention strategies. Expert Rev Anticancer Ther. 2020 Aug 08;: Authors: Mandal CC Abstract INTRODUCTION: Breast cancer is the most common cancer in women throughout the world. Patients who are diagnosed early generally have better prognosis and survivability. Indeed, advanced stage breast cancer often develops osteolytic metastases, leading to bone destruction. Although there are select drugs...
Tue Aug 11, 2020 13:39
Adaptive Wavelet Based MRI Brain Image De-noising. Front Neurosci. 2020;14:728 Authors: Amiri Golilarz N, Gao H, Kumar R, Ali L, Fu Y, Li C Abstract This paper presents a unique approach for wavelet-based MRI brain image de-noising. Adaptive soft and hard threshold functions are first proposed to improve the results of standard soft and hard threshold functions for image de-noising in the wavelet domain. Then, we applied the newly emerged improved...
Tue Aug 11, 2020 13:48
Gender Comparison of Psychological Comorbidities in Tinnitus Patients - Results of a Cross-Sectional Study. Front Neurosci. 2020;14:704 Authors: Fioretti A, Natalini E, Riedl D, Moschen R, Eibenstein A Abstract Background: In the last decades, research focused on gender-related features in patients with tinnitus has often led to controversial results. The complex clinical picture of tinnitus patients often consists of an interdependent relationship...
Tue Aug 11, 2020 13:48
Recent Preclinical Insights Into the Treatment of Chronic Traumatic Encephalopathy. Front Neurosci. 2020;14:616 Authors: Breen PW, Krishnan V Abstract Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition associated with significant mortality and morbidity. The central pathophysiological mechanisms by which repetitive cranial injury results in the neurodegeneration of CTE are poorly understood. Current well-established working...
Tue Aug 11, 2020 13:48
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου