Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Journal of Neurotrauma, Ahead of Print.
Fri Oct 11, 2019 10:00
Abstract Adult onset leukoencephalopathy is a heterogeneous condition that often poses a diagnostic challenge. After infectious, inflammatory, neoplastic, drug‐induced and acquired demyelinating disorders have been excluded, the range of potential genetic causes is daunting. Even in this era of next‐generation sequencing and targeted disease gene panels, the precise genetic diagnosis often remains elusive. In this issue, Okubo and colleagues report that a recently identified GGC repeat expansion...
Thu Oct 10, 2019 14:14
Abstract Objective JC virus (JCV) infection is a lytic infection of oligodendrocytes in progressive multifocal leukoencephalopathy; less common forms of central nervous system manifestations associated with JCV infection include granule cell neuronopathy, encephalopathy, and meningitis. Presented is the first case of fatal JCV encephalopathy after immunosuppressive therapy that included ruxolitinib. Methods Postmortem analysis included next generation sequencing, Sanger sequencing, tissue...
Thu Oct 10, 2019 14:09
ABSTRACT Objective Pathogenic variants in KCNB1, encoding the voltage‐gated potassium channel KV2.1, are associated with developmental and epileptic encephalopathy (DEE). Previous functional studies on a limited number of KCNB1 variants indicated a range of molecular mechanisms by which variants affect channel function, including loss of voltage sensitivity, loss of ion selectivity, and reduced cell‐surface expression. Methods We evaluated a series of 17 KCNB1 variants associated with DEE...
Thu Oct 10, 2019 13:53
Publication date: Available online 11 October 2019Source: Journal of Neuroscience MethodsAuthor(s): Konstanze Simbriger, Inês S. Amorim, Kleanthi Chalkiadaki, Gilliard Lach, Seyed Mehdi Jafarnejad, Arkady Khoutorsky, Christos G. GkogkasAbstractBackgroundThe aim of this study was to develop a method to study genome-wide local translation in biochemically isolated synaptic fractions (synaptoneurosomes). This methodology is of particular interest for neurons, due to the cardinal role of local translational...
Fri Oct 11, 2019 19:51
Publication date: Available online 10 October 2019Source: Brain Research BulletinAuthor(s): Marina F. Souza, Katty Anne A.L. Medeiros, Lívia C.R.F. Lins, José M.M. Bispo, Auderlan M. Gois, Marco Aurelio M. Freire, Murilo Marchioro, José R. SantosAbstractDeltamethrin (DM) is widely used in agriculture, veterinary medicine and control of domestic pests. Epidemiological studies suggest that DM exposure is a risk factor for neurodegenerative disorders such as Parkinson’s (PD) and Alzheimer diseases;...
Fri Oct 11, 2019 19:17
Publication date: Available online 10 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Tomáš Krejčí, Ondřej Krejčí, Zdeněk Večeřa, Martin Chlachula, Dana Šalounová, Radim LipinaABSTRACTObjectivePreoperative third ventricle deformation (known as ‘bowing’) is associated with higher endoscopic third ventriculostomy (ETV) success. In children, the effect of bowing has not to date been systematically studied. Aim of of this study is to determine the effect of bowing on ETV success in...
Fri Oct 11, 2019 17:16
Publication date: Available online 10 October 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Francesco Certo, Massimiliano Maione, Roberto Altieri, Marco Garozzo, Giada Toccaceli, Simone Peschillo, Giuseppe M.V. BarbagalloAbstractObjectiveChronic subdural hematoma (CSH) is a common neurosurgical disease among elderly population with concomitant degenerative neurological disorders. This is a retrospective series-control analysis of prospectively collected data, aiming to show advantages...
Fri Oct 11, 2019 17:16
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Ismail Zaed, Luca Attuati, Concezione Tommasino, Enrico Massimo Arosio, Pierina Navarria, Antonella Stravato, Giovanni Colombo, Piero PicozziAbstractBackgroundShort-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) is a primary headache syndrome with an unclear pathogenesis, and only in very few cases, SUNCT is secondary to known lesions (secondary SUNCT). Several...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Brice A. Kessler, Michael P. Catalino, J. Dedrick JordanAbstractBackground/ObjectiveThe mortality index, or the ratio of observed to expected mortality, is a reported quality metric that is assumed to directly reflect patient care. However, documentation and coding that does not utilize knowledge of how a reported mortality index is derived may reflect poorly on a hospital or service line. We present our effort...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Houman Sotoudeh, Philip R. Chapman, Ehsan Sotoudeh, Aparna Singhal, Gagandeep Choudhary, Omid ShafaatAbstractBackgroundA rare but important complication related to otherwise uneventful brain and spine surgery is becoming more recognized and more frequently reported in the medical literature. This has been variably labelled as pseudohypoxic brain swelling (PHPS) or postoperative hypotension-associated venous congestion...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Alireza Mansouri, Alexandre Boutet, Gavin Elias, Jurgen Germann, Han Yan, Harish Babu, Andres M. Lozano, Taufik ValianteAbstractBackgroundDepression following resection of diffuse low-grade gliomas (DLGG) has rarely been described. The location of the tumor or surgical route are among a multitude of potential causes. Lesion-network mapping (LNM), leveraging high quality resting-state fMRI data from large samples...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Mauro Morassi, Oscar Vivaldi, Milena Cobelli, Barbara Liserre, Fausto Zorzi, Claudio BnàAbstractBackgroundrosette forming glioneuronal tumors (RGNTs) with multifocal growth throughout the ventricular system are extremely rare, and only one case of RGNT with dissemination limited to supratentorial ventricles has previously been reported. Recent evidence based on molecular data suggest that low grade glioneuronal...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Constantin Tuleasca, Ian Paddick, John W. Hopewell, Bleddyn Jones, William T. Millar, Hussein Hamdi, Denis Porcheron, Marc Levivier, Jean RégisAbstractObjectivesHow variations of treatment time affect the safety/efficacy of Gamma Knife (GK) radiosurgery is a matter of considerable debate. Due to the relative simplicity of treatment planning for trigeminal neuralgia (TN) this question has been addressed in a group...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Cristina Sánchez Carabias, Pedro A. Gomez, Irene Panero, Carla Eiriz, Ana María Castaño-León, Javier Egea, Alfonso Lagares, i+12 Neurotraumatology Group collaborators, Igor Paredes, Jose Antonio Fernández Alén, Luis Miguel Moreno-Gómez, Daniel García-Pérez, Mario Chico-Fernández, Jesús Barea-MendozaAbstractObjectiveThe volume and location of intracranial hematomas are well-known prognostic factors for traumatic...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Kevin A. Shah, Jeffrey M. Katz
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): G. Damian Brusko, Evan Luther, Allan D. LeviAbstractBackgroundCervical disc arthroplasty (CDA) is now a widely accepted alternative to anterior cervical interbody fusion, which is known to reduce normal cervical motion and increase the incidence of adjacent segment disease. Although multiple studies report the use of cervical disc arthroplasty to treat multi-level cervical disease, this is the first report in the...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Max Zimmermann, Karl Rössler, Martin Kaltenhäuser, Peter Grummich, Bing Yang, Michael Buchfelder, Arnd Doerfler, Konrad Kölble, Andreas StadlbauerAbstractBackgroundNeurosurgical decisions regarding interventions close to brain areas with language-related functions remain highly challenging because of the risk of postoperative dysfunction. To minimize these risks, improvements in the preoperative mapping of language-related...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Shintaro Arai, Tohru Mizutani, Tatsuya Sugiyama, Kenji Sumi, Masaki Matsumoto, Hirotaka Okumura, Katsuyoshi ShimizuAbstractObjectiveTo carry out surgery safely for vessels in which stents were placed, it is essential to have knowledge of what would happen if the stents were clamped or cut. Using all stents that are permitted in Japan, we recorded with surgical microscope in detail the behavior of the stents when...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Kristin Huntoon, Mostafa Eltobgy, Ahmed Mohyeldin, J. Bradley ElderAbstractBackgroundRadiofrequency ablation (RFA) focally destroys abnormal or dysfunctional tissue using thermal energy generated from alternating current. The utilization of RFA has gained popularity as a minimally invasive procedure for the treatment of skeletal metastases with a particular focus on palliative pain treatments to the spine, pelvis,...
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Panagiotis Kerezoudis
Fri Oct 11, 2019 15:17
Publication date: Available online 10 October 2019Source: World NeurosurgeryAuthor(s): Chao-Yuan Ge, Ding-Jun Hao, M.D, Le-Qun Shan
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Alexander X. Tai, Aalap Herur-Raman, Walter C. Jean
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Mathangi Sridharan, Azeem Tariq Malik, Jeffery Kim, Safdar N. Khan, Elizabeth YuAbstractBackgroundObesity has been shown to be associated with higher rates of complications following lumbar spine surgery. However, the evidence regarding the impact of body mass index (BMI) on outcomes following posterior cervical fusions remains limited.MethodsThe 2012-2017 American College of Surgeons – National Surgical Quality...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Marco Fricia, Giuseppe Emmanuele Umana, Gianluca Scalia, Giuseppe Raudino, Maurizio Passanisi, Angelo Spitaleri, Salvatore CiceroAbstractBackgroundThe development of a delayed acute epidural hematoma (DEDH) represents a very rare event, characterized by a high mortality rate. It is defined as an extradural bleeding not evident at the first brain computed tomography (CT) scan performed after traumatic brain injury...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Kohei Kuroshima, Takahiro Waki, Aritetsu Kanemura, Kenjiro Ito, Ryosuke Kuroda
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Daniel M.S. Raper, W. Caleb Rutledge, Ethan A. Winkler, Adib A. AblaAbstractDespite a variety of technologies that are available for treatment of complex intracranial aneurysms, certain anatomic configurations remain challenging to address endovascularly. A patient was found to have an incidental 12 x 11 x 10 mm, wide-necked right posterior communicating artery aneurysm with a fetal origin of the posterior cerebral...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Ricardo H. Menéndez, Patricio Thompson, Horacio Barea, Ana P. Lisdero, Javier Lew, Jaqueline Elvira, Pablo E. Lehrner, Horacio A. SoleAbstractBackgroundCoexistence of sinonasal and skull-base tumors is uncommon but possible, and the endonasal route seems to be the best option to manage simultaneously both lesions. We report the first case in English literature of concomitant sphenoid sinus inverted papilloma (IP)...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Amit Narang, Chandni Maheshwari, Varun Aggarwal, Puneet Bansal, Paramdeep SinghAbstractWe present a case of intracranial meningioma in a young female who was postoperatively diagnosed to have Gorlin-Goltz syndrome based on presence of calcification of bilateral tent and falx . Postoperatively detailed clinical and radiological assessment helped us identify many other syndromic features and patient was promptly advised...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Nida Fatima, Antonio Meola, Erqi Pollom, Steven D. Chang, Scott SoltysAbstractObjectivesHistorically, it is stated that large intracranial tumors, herein defined as a maximum dimension of > 3cm or tumor volume >14.2 cm3, are not candidates for Stereotactic Radiosurgery (SRS). We report outcomes of patients with large benign intracranial tumors treated with SRS.MethodsWith IRB approval, we retrospectively identified...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Alessandro Pesce, Mauro Palmieri, Giuseppa Zancana, Maurizio Salvati, Antonio Santoro, Antonino Raco, Alessandro FratiAbstractBackgroundBrain aneurysms (BA) represent the most common intracranial vascular condition, with an overall incidence of 1-2%. Among the described common causes of their initial formation and growth the role of radiation therapy (RT) has been described in seldom reports. The aim of the present...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Tianwei Wang, Yanping Yang, Xiaoke Xu, Xiaodong Niu, Renhao Yang, Ting Gao, Yu Miao, Qing Mao, Yongming QiuAbstractObjectiveThis study aimed to perform a survival analysis of patients with multicentric low-grade gliomas(MLGGs) and to assess the influence of various prognostic factors on progression-free survival(PFS) and overall survival(OS).MethodsA literature search on Web of Science and PubMed was performed for...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Zaid Aljuboori, Kimberley Meyer, Dale Ding, Robert JamesAbstractObjectiveTraumatic pseudoaneurysms of the proximal middle cerebral artery (MCA) segments are challenging to treat. We describe the management of traumatic internal carotid artery (ICA) and MCA pseudoaneurysms with flow diversion.MethodsA 19-year-old male sustained a gunshot wound to the head. Delayed digital subtraction angiography (DSA) showed de novo...
Fri Oct 11, 2019 15:17
Publication date: Available online 9 October 2019Source: World NeurosurgeryAuthor(s): Chad F. Claus, Evan Lytle, Ascher Kaufmann, Doris Tong, Matthew Bahoura, Lucas Garmo, Boyd Richards, Teck M. Soo, Clifford HousemanAbstractBackgroundMinimally invasive fusion (MIS) of the SI joint has gained popularity for the treatment of refractory dysfunction. The purpose of this study was to compare clinical outcomes between MIS SI joint fusion between cylindrical threaded implants (CTI) and triangular dowel...
Fri Oct 11, 2019 15:17
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