- Highly sensitive detection of GATA1 mutations in patients with myeloid leukemia associated with Down syndrome by combining Sanger and targeted next generation sequencingAbstract Myeloid leukemia associated with Down syndrome (ML‐DS) is characterized by a predominance of acute megakaryoblastic leukemia, the presence of GATA1 mutations and a favorable outcome. Because DS children can also develop conventional acute myeloid leukemia with unfavorable outcome, detection of GATA1 mutations is important for diagnosis of ML‐DS. However, myelofibrosis and the significant frequency of dry taps have hampered practical scr
ScienceDirect Publication: Photodiagnosis and Photodynamic Therapy
- Antibacterial Photodynamic Therapy Mediated by 5-aminolevulinic acid on methicillin-resistant <em>Staphylococcus aureus</em>Publication date: Available online 13 October 2019Source: Photodiagnosis and Photodynamic TherapyAuthor(s): Jianhua Huang, Mingquan Guo, Shengkai Jin, Minfeng Wu, Chen Yang, Guolong Zhang, Peiru Wang, Jie Ji, Qingyu Zeng, Xiuli Wang, Hongwei WangAbstractIn recent years, the emergence of drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), has brought great difficulties to clinical treatment. Antibacterial photodyna
Laryngo-Rhino-Otologie
- Schwindel, von der Fahreignung mit Führerschein zum Führerschein ohne Fahreignung: Sind die aktuellen Leitlinien gerechtfertigt?Laryngo-Rhino-Otol 2019; 98: 674-684DOI: 10.1055/a-0960-6464Die seit dem Jahre 2014 gültigen und verpflichtend anzuwendenden Begutachtungsleitlinien zur Fahreignung von Patienten mit Schwindel und Gleichgewichtsstörungen (dort „Störungen des Gleichgewichtssinnes“ genannt) werden kritisch diskutiert. Bei allem Respekt vor der sorgfältigen Arbeit der Expertenkom
- Oberlandesgericht entscheidet: Medizinisch wissenschaftliche Leitlinien sind nicht justiziabelLaryngo-Rhino-Otol 2019; 98: 722-724DOI: 10.1055/a-0954-7526© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
- Nasale mukoziliäre Clearance und Vitamin-D-MangelLaryngo-Rhino-Otol 2019; 98: 667-668DOI: 10.1055/a-0854-6942Akcan FA et al. Evaluation of nasal mucociliary clearance time in patients with Vitamin-D deficiency. Eur Arch Otorhinolaryngol 2019; doi: 10.1007/s00405–019–05286-y HNO-Ärzte aus der Türkei untersuchten die Zeitdauer der nasalen mukoziliären Clearance (NMC) bei Patienten mit Vitamin-D-Mangel.
- Ausbildungscurriculum zum Zertifikat „Diagnostik und Therapie oropharyngealer Dysphagien, inklusive FEES“ der Deutschen Gesellschaft für Phoniatrie und Pädaudiologie und der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-ChirurgieLaryngo-Rhino-Otol 2019; 98: 695-700DOI: 10.1055/a-0987-0517 Hintergrund In Deutschland leiden ca. 5 Millionen Menschen jeden Lebensalters an einer Dysphagie. Durch den demografischen Wandel und die verbesserte medizinische Versorgung ist mit einer Zunahme der Inzidenz von Schluckstörungen zu rechnen. Die Dysphagie ist mit einer erhöhten Morbiditäts-
- Septumplastik: wie wirken Schmerzmittel-angereicherte Nasentamponaden?Laryngo-Rhino-Otol 2019; 98: 668-669DOI: 10.1055/a-0898-8603Simsek T et al. The effect of lidocaine and tramadol in nasal packs on pain after septoplasty. Eur Arch Otorhinolaryngol 2019; doi: 10.1007/s00405–019–05306-x Türkische HNO-Ärzte verglichen die postoperative schmerzstillende Wirkung von mit Tramadol und Lidocain getränkten Nasentamponaden mittels visueller
- Fragen für die FacharztprüfungLaryngo-Rhino-Otol 2019; 98: 742-743DOI: 10.1055/a-0954-7537© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
- Pulsatiler Tinnitus: Korrektur sigmoider Sinuswand-Anomalien effektive TherapieLaryngo-Rhino-Otol 2019; 98: 669-670DOI: 10.1055/a-0898-8792Zhang C et al. Physical and psychological outcomes of simple sigmoid sinus bony wall repair for pulsatile tinnitus due to sigmoid sinus wall anomalies. Eur Arch Otorhinolaryngol 2019; 276: 1327–1334 Ein pulsatiler Tinnitus (PT) aufgrund von Anomalien der sigmoiden Sinuswand (SSWA) ist eine häufige
- Aktuelle Therapiekonzepte bei oberflächlichen malignen TumorenLaryngo-Rhino-Otol 2019; 98: 685-694DOI: 10.1055/a-0960-6490In dieser Übersichtsarbeit werden die diagnostischen und therapeutischen Möglichkeiten bei den häufigsten malignen oberflächlichen Tumoren abgehandelt, hierzu gehören Basalzellkarzinome, konjunktivale Lymphome, Plattenepithelkarzinome und maligne Melanome und deren Vorstufen. Entscheidend für die rich
- Taschenatlas der SchnittbildanatomieLaryngo-Rhino-Otol 2019; 98: 671-671DOI: 10.1055/a-1003-0948© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
- Off-label Anwendung einer budesonidhaltigen Suspension für die Behandlung einer lymphozytären ÖsophagitisLaryngo-Rhino-Otol 2019; 98: 718-721DOI: 10.1055/a-0747-7023 Einleitung Die lymphozytäre Ösophagitis (Englisch: lymphocytic esophagitis-LyE) ist eine seltene chronisch-entzündliche Erkrankung der Speiseröhre, die klinisch ähnliche Charakteristika wie die eosinophile Ösophagitis aufweist. Der wichtigste Bestandteil der Behandlung sind die Protonenpu
- Verruca vulgaris laryngisLaryngo-Rhino-Otol 2019; 98: 672-673DOI: 10.1055/a-0954-7503© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
- Chirurgie des Larynx: Maligne LäsionenLaryngo-Rhino-Otol 2019; 98: 725-741DOI: 10.1055/a-0896-9444Bei der Chirurgie maligner Kehlkopftumoren ist es das Ziel, dass die Patienten postoperativ eine möglichst hohe Lebensqualität zurückerlangen. Unter onkologischem Aspekt ist einerseits so radikal wie nötig und andererseits so funktionserhaltend wie möglich zu behandeln. Dieser Beitrag soll einen Überblick
- Plastisch-rekonstruktive GesichtschirurgieLaryngo-Rhino-Otol 2019; 98: 745-750DOI: 10.1055/a-0954-7581© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
- Liebe Kolleginnen und Kollegen, Liebe Leser der LRO,Laryngo-Rhino-Otol 2019; 98: 663-664DOI: 10.1055/a-0954-7467© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
The European Gastrointestinal Motility Society
- The effect of rikkunshito on gastrointestinal symptoms and gastric motor function: The first study in a Belgian functional dyspepsia populationRikkunshito, a traditional Kampo medicine, has shown efficacy to treat functional dyspepsia (FD) in controlled trials in Japan. In a randomized, placebo‐controlled, 4‐week treatment cross‐over study in Belgian FD patients, intragastric pressure was numerically, but not significantly, lower after rikkunshito compared with baseline and placebo. Early satiation and postprandial fullness decreased after rikkunshito compared to baseline. Rikkunshito w
http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino
- Transoral robotic tongue base reduction and supraglottoplasty combined with maxillomandibular advancement: a new option for selected sleep apnea patients? Preliminary report.Related ArticlesTransoral robotic tongue base reduction and supraglottoplasty combined with maxillomandibular advancement: a new option for selected sleep apnea patients? Preliminary report. Eur Arch Otorhinolaryngol. 2019 Oct 12;: Authors: Dallan I, Cristofani-Mencacci L, Seccia V, Cambi C, Fiacchini G, Berrettini S, Brevi B Abstract PURPOSE: Transoral robotic surgery (TORS) and maxillo-mandibular a
- Vestibular implant: does it really work? A systematic review.Related ArticlesVestibular implant: does it really work? A systematic review. Braz J Otorhinolaryngol. 2019 Sep 20;: Authors: Azevedo YJ, Ledesma ALL, Pereira LV, Oliveira CA, Bahmad Junior F Abstract INTRODUCTION: People with vestibular loss present a deficit in the vestibular system, which is primarily responsible for promoting postural control, gaze stabilization, and spatial orientation while the
- Spontaneous Cerebrospinal Fluid Leak Presenting as Chronic Rhinitis.Related ArticlesSpontaneous Cerebrospinal Fluid Leak Presenting as Chronic Rhinitis. J Allergy Clin Immunol Pract. 2019 Oct 09;: Authors: Marenco-Hillembrand L, Alvarez-Elcoro S, Olomu OU, Quinones-Hinojosa A, Gupta V, Gonzalez-Estrada A PMID: 31606393 [PubMed - as supplied by publisher]
- Efficacy and tolerability of a custom-made Narval mandibular repositioning device for the treatment of obstructive sleep apnea: ORCADES study 2-year follow-up data.Related ArticlesEfficacy and tolerability of a custom-made Narval mandibular repositioning device for the treatment of obstructive sleep apnea: ORCADES study 2-year follow-up data. Sleep Med. 2019 Jun 12;63:64-74 Authors: Attali V, Vecchierini MF, Collet JM, d'Ortho MP, Goutorbe F, Kerbrat JB, Leger D, Lavergne F, Monaca C, Monteyrol PJ, Morin L, Mullens E, Pigearias B, Martin F, Tordjman F, Khemliche H, Lerousseau L,
- [Cervical cancer: Current situation and management in Morocco].Related Articles[Cervical cancer: Current situation and management in Morocco]. Bull Cancer. 2019 Oct 09;: Authors: Belglaiaa E, Mougin C Abstract With more than 3300 new cases and almost 2500 deaths each year, cervical cancer (CC) ranks second among female cancers in Moroccan women. The majority of cases occurs in women aged 50 and over. In absence of a national cancer registry, data published in Mo
- Association Between Serum C-Peptide Level and Cardiovascular Autonomic Neuropathy According to Estimated Glomerular Filtration Rate in Individuals with Type 2 DiabetesExp Clin Endocrinol DiabetesDOI: 10.1055/a-1017-3048 Objective To investigate the association between serum C-peptide level and cardiovascular autonomic neuropathy (CAN) in individuals with type 2 diabetes mellitus (DM) according to estimated glomerular filtration rate (eGFR) Methods In a cross-sectional study, we examined 939 individuals with type 2 DM. We measured fasting C-peptide, 2-hour postprandial C-peptide, and ΔC-peptide (postprand
European Journal of Nuclear Medicine and Molecular Imaging
- Head-to-head comparison of tau positron emission tomography tracers [ 18 F]flortaucipir and [ 18 F]RO948Abstract Purpose [18F]flortaucipir binds to paired helical filament tau and accurately identifies tau in Alzheimer’s disease (AD). However, “off-target” binding interferes with the quantification of [18F]flortaucipir in several brain regions. Recently, other tau PET tracers have been developed. Here, we compare [18F]flortaucipir with the novel tau tracer [18F]RO948 head-to-head in vivo
- Nicotinic receptors modulate skin perfusion during normothermia, and have a limited role in skin vasodilatation and sweating during hyperthermiaNew Findings •What is the central question of this study? We evaluated the role of nicotinic receptors in the regulation of normothermic cutaneous blood flow and cutaneous vasodilatation and sweating during whole‐body heating induced following resting in a non‐heat‐stress condition. •What is the main finding and its importance? Nicotinic receptors modulated cutaneous vascular tone during rest in a non‐heat stress condition and early stage o
- The nitric oxide synthase contribution to cutaneous vasodilation and sweating in black‐African and Caucasian descent men during exercise in the heatNew Findings •What is the central question of this study? Nitric oxide modulates cutaneous vasodilation and sweating during an exercise‐heat stress in young men. However, it remains uncertain whether these effects are reduced in black‐African descendants who commonly demonstrate reduced nitric oxide bioavailability. Therefore, we assessed whether black‐African descendants display reduced nitric oxide‐dependent cutaneous vasodilation and sweat
- Oestrogen receptor agonists ERα and ERβ ameliorate oxidative brain injury and improve memory dysfunction in rats with an epileptic seizureNEW FINDINGS •What is the central question of this study? Could different hormonally active substances, including oestrogen receptor (ER) agonists, protect against oxidative brain damage and memory impairment induced by a single epileptic seizure in rats? If so, which signalling mechanisms are involved in their anti‐inflammatory effects? •What is the main finding and its importance? Chronic administration of oestrogen, progesterone, ER mo
- Inhibition of microRNA-875-5p promotes radioiodine uptake in poorly differentiated thyroid carcinoma cells by upregulating sodium–iodide symporterAbstract Background and Aim Poorly differentiated thyroid carcinoma (PDTC) is an endocrine malignancy that is challenging to treat due to its limited radioiodine uptake. microRNAs (miRNAs or miRs) have been shown to be useful in treating many types of tumors, including PDTC. This study aims to evaluate the potential effect of miR-875-5p on the radioiodine uptake of PDTC and to clarify
- Quality of life of children with hearing loss in special and mainstream education: A longitudinal study.Related ArticlesQuality of life of children with hearing loss in special and mainstream education: A longitudinal study. Int J Pediatr Otorhinolaryngol. 2019 Oct 05;128:109701 Authors: van der Straaten TFK, Rieffe C, Soede W, Netten AP, Dirks E, Oudesluys-Murphy AM, Dekker FW, Böhringer S, Frijns JHM, DECIBEL Collaborative study group Abstract OBJECTIVES: To compare the quality of life (QoL) of child
- Radiologic, genetic, and endocrine findings in isolated congenital nasal pyriform aperture stenosis patients.Related ArticlesRadiologic, genetic, and endocrine findings in isolated congenital nasal pyriform aperture stenosis patients. Int J Pediatr Otorhinolaryngol. 2019 Oct 05;128:109705 Authors: Ruda J, Grischkan J, Allarakhia Z Abstract BACKGROUND: Congenital nasal pyriform aperture stenosis (CNPAS) is a rare cause of upper airway obstruction in neonates. It can occur either associated with a solitary me
- Selected cytokines in hypertrophic adenoids in children suffering from otitis media with effusion.Related ArticlesSelected cytokines in hypertrophic adenoids in children suffering from otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2019 Oct 04;128:109700 Authors: Zelazowska-Rutkowska B, Skotnicka B, Hassmann-Poznanska E, Cylwik B Abstract OBJECTIVES: The aim of the current study was to assess the levels of MMP-8, MMP-9 and TIMP-1 in the group of children with adenoids who suffered fr
- Determining concordance and cost impact of otoacoustic emission and automated auditory brainstem response in newborn hearing screening in a tertiary hospital.Related ArticlesDetermining concordance and cost impact of otoacoustic emission and automated auditory brainstem response in newborn hearing screening in a tertiary hospital. Int J Pediatr Otorhinolaryngol. 2019 Oct 08;128:109704 Authors: Ong KMC, Rivera AS, Chan AL, Chiong CM Abstract OBJECTIVE: This study compared otoacoustic emission (OAE) and automated auditory brainstem response (AABR) in terms
- Binaural processing and phonological awareness in Australian Indigenous children from the Northern Territory: A community based study.Related ArticlesBinaural processing and phonological awareness in Australian Indigenous children from the Northern Territory: A community based study. Int J Pediatr Otorhinolaryngol. 2019 Oct 05;128:109702 Authors: Sharma M, Wigglesworth G, Savage G, Demuth K Abstract OBJECTIVE: Research has found that otitis media (OM) is highly prevalent in Australian Indigenous children, and repeated bouts of OM i
- Meta-analysis of laparoscopic groin hernia repair with or without mesh fixation.Related ArticlesMeta-analysis of laparoscopic groin hernia repair with or without mesh fixation. Int J Surg. 2019 Oct 10;: Authors: Eltair M, Hajibandeh S, Hajibandeh S, Balakrishnan S, Alyamani A, Radoi D, Goh YL, Hanif M, Kumar Y, Mobarak D Abstract OBJECTIVES: To evaluate comparative outcomes of laparoscopic repair of groin hernia with and without mesh fixation. METHODS: MEDLINE; EMBASE;
- A role for Oncostatin M in the impairment of glucose homeostasis in obesity.Related ArticlesA role for Oncostatin M in the impairment of glucose homeostasis in obesity. J Clin Endocrinol Metab. 2019 Oct 13;: Authors: Piquer-Garcia I, Campderros L, Taxerås SD, Gavaldà-Navarro A, Pardo R, Vila M, Pellitero S, Martínez E, Tarascó J, Moreno P, Villarroya J, Cereijo R, González L, Reyes M, Rodriguez-Fernández S, Vives-Pi M, Lerin C, Elks CM, Stephens JM, Puig-Domingo M, Villarroya F, Villena JA, S
- A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update.Related ArticlesA Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update. J Clin Endocrinol Metab. 2019 Oct 13;: Authors: Giustina A, Barkan A, Beckers A, Biermasz N, Biller BMK, Boguszewski C, Bolanowski M, Bonert V, Bronstein MD, Casanueva FF, Clemmons D, Colao A, Ferone D, Fleseriu M, Frara S, Gadelha MR, Ghigo E, Gurnell M, Heaney AP, Ho K, Ioachimescu A, Katznelson L, Kelestimur F, Kopchi
- Effects of anticoagulant and antiplatelet agents in severe traumatic brain injury in an asian population - A matched case-control study.Related ArticlesEffects of anticoagulant and antiplatelet agents in severe traumatic brain injury in an asian population - A matched case-control study. J Clin Neurosci. 2019 Oct 09;: Authors: Qiu L, Han JX, See AAQ, King NKK Abstract The use of anticoagulation and antiplatelet agents (ACAP) has steadily increased over recent years. However, the effects of ACAP on traumatic brain injuries (TBI) are n
- Occipital neuralgia: A neurosurgical perspective.Related ArticlesOccipital neuralgia: A neurosurgical perspective. J Clin Neurosci. 2019 Oct 09;: Authors: Janjua MB, Reddy S, El Ahmadieh TY, Ban VS, Ozturk AK, Hwang SW, Samdani AF, Passias PG, Welch WC, Arlet V Abstract Occipital neuralgia typically arises in the setting of nerve compression by fibrosis, surrounding anatomic structures, or osseous pathology, such as bone spurs or hypertrophic atlan
fireflyglobal
- Firefly Returning for Their 6th Year at Medica Hall 16 / D32-15Firefly will be exhibiting for their 6th year at the MEDICA in Dusseldorf, Germany from November 18th through 21st in Hall 16 / D32-15. There will be live demonstrations of:DE1250 Wireless Endoscopy Camera R3800 Full HD 1080p Endoscopy Camera System DE570 HD Wireless Video Otoscope DE550 Wireless Video Otoscope DE500 Digital Video Otoscope DE370 HD Wireless Digital Dermatoscope DE350 Wireless Digital Dermatoscope DE300 Wired Digital Derma
NEJM : Research
- Conservative Oxygen Therapy during Mechanical Ventilation in the ICUThe provision of supplemental oxygen to patients in the intensive care unit (ICU) who require invasive mechanical ventilation often exposes them to a high fraction of inspired oxygen (Fio2) and a higher-than-normal partial pressure of arterial oxygen (Pao2). Among adults undergoing mechanical…
Annals of Clinical Microbiology and Antimicrobials - Latest Articles
- Evaluation of serological test of Zika in an endemic area of flavivirus in the Colombian CaribbeanThe Zika virus (ZIKV) is an emerging flavivirus transmitted primarily through arthropods, endemic in Africa, Asia, and the Americas, and is considered a global threat by the World Health Organization.
ClinicalTrials
- Roll-over Study to Continue Treatment With the Investigational Drug Rogaratinib and to Further Test Its SafetyCondition: CancerInterventions: Drug: Rogaratinib (BAY1163877); Drug: Combination drugSponsor: BayerNot yet recruiting
- Estimating Setup Uncertainty in Pediatric Proton Therapy Using Volumetric ImagesCondition: Pediatric CancerIntervention: Sponsor: St. Jude Children's Research HospitalNot yet recruiting
- Influence on Cough and Airway Symptoms by Oral CapsaicinCondition: CoughInterventions: Drug: Capsicum Oleoresin; Drug: PlacebosSponsors: Vastra Gotaland Region; Sahlgrenska University Hospital, Sweden; VinnovaRecruiting
- Mediastinoscopy-assisted Transhiatal Esophagectomy VS Minimally Invasive Esophagectomy for Esophageal CancerCondition: Esophageal NeoplasmsInterventions: Procedure: Minimally invasive esophagectomy; Procedure: Mediastinoscopy-assisted transhiatal esophagectomySponsor: Cancer Institute and Hospital, Chinese Academy of Medical SciencesNot yet recruiting
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Δευτέρα 14 Οκτωβρίου 2019
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