IJERPH, Vol. 16, Pages 4153: Changes in Water Soluble Uremic Toxins and Urinary Acute Kidney Injury Biomarkers After 10- and 100-km Runs International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214153 Authors: Wołyniec Kasprowicz Giebułtowicz Korytowska Zorena Bartoszewicz Rita-Tkachenko Renke Ratkowski Acute kidney injury (AKI) is described as a relatively common complication of exercise. In clinical practice the diagnosis...
Mon Oct 28, 2019 02:00
IJERPH, Vol. 16, Pages 4150: Detecting Mortality Trends in the Netherlands Across 625 Causes of Death International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214150 Authors: Marianna Mitratza Anton E. Kunst Jan W. P. F. Kardaun Cause of death (COD) data are essential to public health monitoring and policy. This study aims to determine the proportion of CODs, at ICD-10 three-position level, for which a long-term or short-term trend can be identified,...
Mon Oct 28, 2019 02:00
IJERPH, Vol. 16, Pages 4151: Being Conscious of Water Intake Positively Associated with Sufficient Non-Alcohol Drink Intake Regardless of Seasons and Reasons in Healthy Japanese; the KOBE Study: A Cross Sectional Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16214151 Authors: Tomofumi Nishikawa Naomi Miyamatsu Aya Higashiyama Yoshimi Kubota Yoko Nishida Takumi Hirata Daisuke Sugiyama Kazuyo Kuwabara Sachimi Kubo Yoshihiro...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5371: ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation International Journal of Molecular Sciences doi: 10.3390/ijms20215371 Authors: Domenico Marano Salvatore Fioriniello Francesca Fiorillo Richard J. Gibbons Maurizio D’Esposito Floriana Della Ragione Methyl-CpG binding protein 2 (MeCP2) is a multi-function factor involved in locus-specific transcriptional modulation and the regulation of genome...
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IJMS, Vol. 20, Pages 5376: The Pathogenesis of Sepsis and Potential Therapeutic Targets International Journal of Molecular Sciences doi: 10.3390/ijms20215376 Authors: Min Huang Shaoli Cai Jingqian Su Sepsis is defined as “a life-threatening organ dysfunction caused by a host’s dysfunctional response to infection”. Although the treatment of sepsis has developed rapidly in the past few years, sepsis incidence and mortality in clinical treatment is still...
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IJMS, Vol. 20, Pages 5374: Protective Effect of PBCA Nanoparticles Loaded with Thymulin Against the Relapsing-Remitting Form of Experimental Autoimmune Encephalomyelitis in Mice International Journal of Molecular Sciences doi: 10.3390/ijms20215374 Authors: Sergey M. Lunin Maxim O. Khrenov Olga V. Glushkova Svetlana B. Parfenyuk Tatyana V. Novoselova Elena G. Novoselova Relapsing–remitting experimental autoimmune encephalomyelitis (rEAE) in mice is a model that...
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IJMS, Vol. 20, Pages 5375: Advances in Research on Diabetes by Human Nutriomics International Journal of Molecular Sciences doi: 10.3390/ijms20215375 Authors: Xinmin Ren Xiangdong Li The incidence and prevalence of diabetes mellitus (DM) have increased rapidly worldwide over the last two decades. Because the pathogenic factors of DM are heterogeneous, determining clinically effective treatments for DM patients is difficult. Applying various nutrient analyses has yielded new insight...
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IJMS, Vol. 20, Pages 5372: Structure and Junctional Complexes of Endothelial, Epithelial and Glial Brain Barriers International Journal of Molecular Sciences doi: 10.3390/ijms20215372 Authors: Mariana Castro Dias Josephine A. Mapunda Mykhailo Vladymyrov Britta Engelhardt The homeostasis of the central nervous system (CNS) is ensured by the endothelial, epithelial, mesothelial and glial brain barriers, which strictly control the passage of molecules, solutes and immune cells....
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IJMS, Vol. 20, Pages 5369: BRAF-Mutated Colorectal Cancer: Clinical and Molecular Insights International Journal of Molecular Sciences doi: 10.3390/ijms20215369 Authors: Caputo Santini Bardasi Cerma Casadei-Gardini Spallanzani Andrikou Cascinu Gelsomino Colorectal cancer (CRC) is one of the leading causes of mortality and morbidity in the world. It is a heterogeneous disease, which can be classified into different subtypes, characterized by specific molecular...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5370: A Shifty Target: Tumor-Initiating Cells and Their Metabolism International Journal of Molecular Sciences doi: 10.3390/ijms20215370 Authors: Bezuidenhout Shoshan Tumor-initiating cells (TICs), or cancer stem cells, constitute highly chemoresistant, asymmetrically dividing, and tumor-initiating populations in cancer and are thought to play a key role in metastatic and chemoresistant disease. Tumor-initiating cells are isolated from cell lines and clinical...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5366: Cordycepin Enhances Radiosensitivity in Oral Squamous Carcinoma Cells by Inducing Autophagy and Apoptosis Through Cell Cycle Arrest International Journal of Molecular Sciences doi: 10.3390/ijms20215366 Authors: Ho Wu Lin Wu Chiu Yeh Huang Wang Oral squamous cell carcinoma (OSCC) is one of the most common cancers worldwide and accounts for over 90% of malignant neoplasms of the oral cavity, with a 5-year survival rate of less than...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5367: Reduced Cholinergic Activity in the Hippocampus of Hippocampal Cholinergic Neurostimulating Peptide Precursor Protein Knockout Mice International Journal of Molecular Sciences doi: 10.3390/ijms20215367 Authors: Madokoro Yoshino Kato Sato Mizuno Kanamori Shimazawa Hida Hara Yoshida Borlongan Ojika Matsukawa The cholinergic efferent network from the medial septal nucleus to the hippocampus has an important role...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5365: Kinetic Models of Secondary Active Transporters International Journal of Molecular Sciences doi: 10.3390/ijms20215365 Authors: Burtscher Schicker Freissmuth Sandtner Kinetic models have been employed to understand the logic of substrate transport through transporters of the Solute Carrier (SLC) family. All SLC transporters operate according to the alternate access model, which posits that substrate transport occurs in a closed loop of partial reactions...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5368: Reduction-Triggered Paclitaxel Release Nano-Hybrid System Based on Core-Crosslinked Polymer Dots with a pH-Responsive Shell-Cleavable Colorimetric Biosensor International Journal of Molecular Sciences doi: 10.3390/ijms20215368 Authors: Seul Gi Kim Benny Ryplida Pham Thi My Phuong Hyun Jeong Won Gibaek Lee Suk Ho Bhang Sung Young Park Herein, we describe the fabrication and characterization of carbonized disulfide core-crosslinked polymer dots...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5364: Molecular Links between Central Obesity and Breast Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20215364 Authors: Zimta Tigu Muntean Cenariu Slaby Berindan-Neagoe : Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to incidence and mortality. In recent years, the negative role of obesity during BC development and progression has been made abundantly clear in several studies. However,...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5363: Proteomic Investigation of S-Nitrosylated Proteins During NO-Induced Adventitious Rooting of Cucumber International Journal of Molecular Sciences doi: 10.3390/ijms20215363 Authors: Lijuan Niu Jihua Yu Weibiao Liao Jianming Xie Jian Yu Jian Lv Xuemei Xiao Linli Hu Yue Wu Nitric oxide (NO) acts an essential signaling molecule that is involved in regulating various physiological and biochemical processes in plants. However, whether S-nitrosylation...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5360: Genome-Wide Analysis of the Lateral Organ Boundaries Domain (LBD) Gene Family in Solanum tuberosum International Journal of Molecular Sciences doi: 10.3390/ijms20215360 Authors: Hengzhi Liu Minxuan Cao Xiaoli Chen Minghui Ye Peng Zhao Yunyou Nan Wan Li Chao Zhang Lingshuang Kong Nana Kong Chenghui Yang Yue Chen Dongdong Wang Qin Chen Lateral organ boundaries domain (LBD) proteins belong to a particular class of transcription...
Mon Oct 28, 2019 02:00
IJMS, Vol. 20, Pages 5362: The Role of Measurable Residual Disease (MRD) in Hematopoietic Stem Cell Transplantation for Hematological Malignancies Focusing on Acute Leukemia International Journal of Molecular Sciences doi: 10.3390/ijms20215362 Authors: Anna Czyz Arnon Nagler The significance of measurable residual disease (MRD) in hematopoietic stem cell transplantation (HSCT) is well recognized in different hematological malignancies, but the evidence indicate that pre-transplant...
Mon Oct 28, 2019 02:00
JCM, Vol. 8, Pages 1806: Risk of Preeclampsia and Adverse Pregnancy Outcomes after Heterologous Egg Donation: Hypothesizing a Role for Kidney Function and Comorbidity Journal of Clinical Medicine doi: 10.3390/jcm8111806 Authors: Federica Fassio Rossella Attini Bianca Masturzo Benedetta Montersino Antoine Chatrenet Patrick Saulnier Gianfranca Cabiddu Alberto Revelli Gianluca Gennarelli Isabella Bianca Gazzani Elisabetta Muccinelli Claudio Plazzotta Guido...
Mon Oct 28, 2019 02:00
JCM, Vol. 8, Pages 1807: Smartphone Apps Targeting Hazardous Drinking Patterns among University Students Show Differential Subgroup Effects over 20 Weeks: Results from a Randomized, Controlled Trial Journal of Clinical Medicine doi: 10.3390/jcm8111807 Authors: Anne H. Berman Claes Andersson Mikael Gajecki Ingvar Rosendahl Kristina Sinadinovic Matthijs Blankers Overconsumption of alcohol, from hazardous to excessive, heavy, and harmful levels, is common among university...
Mon Oct 28, 2019 02:00
Medicina, Vol. 55, Pages 717: Usefulness of Protocolized Point-of-Care Ultrasonography for Patients with Acute Renal Colic Who Visited Emergency Department: A Randomized Controlled Study Medicina doi: 10.3390/medicina55110717 Authors: Kim Jo Kim Hwang Park Shin Sim Cha Yoon Background and Objectives: Ultrasonography is useful in evaluating patients with renal colic and it has high sensitivity and specificity for diagnosing ureter stones by revealing hydronephrosis....
Mon Oct 28, 2019 02:00
Medicina, Vol. 55, Pages 716: Pleurotus highking Mushroom Induces Apoptosis by Altering the Balance of Proapoptotic and Antiapoptotic Genes in Breast Cancer Cells and Inhibits Tumor Sphere Formation Medicina doi: 10.3390/medicina55110716 Authors: Haque Islam Background and objectives: Mushrooms that have medicinal properties are part of many traditional diets. The aim of the present study was to use the human breast cancer cell line MCF-7 to investigate the anticancer activity of...
Mon Oct 28, 2019 02:00
Medicina, Vol. 55, Pages 715: Knowledge about Disease, Medication Therapy, and Related Medication Adherence Levels among Patients with Hypertension Medicina doi: 10.3390/medicina55110715 Authors: Gavrilova Bandere Rutkovska Šmits Mauriņa Poplavska Urtāne Background and Objectives: A particular problem in cardiology is poor adherence to pharmacological treatment among patients with hypertension. It is known that approximately half of these patients do not use...
Mon Oct 28, 2019 02:00
Microorganisms, Vol. 7, Pages 502: The Human Milk Microbiota is Modulated by Maternal Diet Microorganisms doi: 10.3390/microorganisms7110502 Authors: Marina Padilha Niels Banhos Danneskiold-Samsøe Asker Brejnrod Christian Hoffmann Vanessa Pereira Cabral Julia de Melo Iaucci Cristiane Hermes Sales Regina Mara Fisberg Ramon Vitor Cortez Susanne Brix Carla Romano Taddei Karsten Kristiansen Susana Marta Isay Saad Human milk microorganisms contribute not...
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Microorganisms, Vol. 7, Pages 500: The Influence of the Degradation of Tetracycline by Free Radicals from Riboflavin-5′-Phosphate Photolysis on Microbial Viability Microorganisms doi: 10.3390/microorganisms7110500 Authors: Shiuh-Tsuen Huang Shwu-Yuan Lee Song-Hua Wang Chun-Yi Wu Jeu-Ming P. Yuann Sin He Chien-Wei Cheng Ji-Yuan Liang Tetracycline (TC) is a broad-spectrum antibiotic compound. Wastewater with TC may have an adverse effect on ecosystems. Riboflavin-5′-phosphate...
Mon Oct 28, 2019 02:00
Microorganisms, Vol. 7, Pages 501: A Comparison of Constitutive and Inducible Non-Endogenous Keto-Carotenoids Biosynthesis in Synechocystis sp. PCC 6803 Microorganisms doi: 10.3390/microorganisms7110501 Authors: Menin Lami Musazzi Petrova Santabarbara Casazza The model cyanobacterium Synechocystis sp. PCC 6803 has gained significant attention as an alternative and sustainable source for biomass, biofuels and added-value compounds. The latter category includes keto-carotenoids,...
Mon Oct 28, 2019 02:00
Microorganisms, Vol. 7, Pages 498: Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17 Microorganisms doi: 10.3390/microorganisms7110498 Authors: Lukas Chrast Katsiaryna Tratsiak Joan Planas-Iglesias Lukas Daniel Tatyana Prudnikova Jan Brezovsky David Bednar Ivana Kuta Smatanova Radka Chaloupkova Jiri Damborsky Haloalkane dehalogenases are enzymes with a broad application potential in...
Mon Oct 28, 2019 02:00
Microorganisms, Vol. 7, Pages 499: Elucidating Escherichia Coli O157:H7 Colonization and Internalization in Cucumbers Using an Inverted Fluorescence Microscope and Hyperspectral Microscopy Microorganisms doi: 10.3390/microorganisms7110499 Authors: Yeting Sun Dan Wang Yue Ma Hongyang Guan Hao Liang Xiaoyan Zhao Contamination of fresh cucumbers (Cucumis sativus L.) with Escherichia coli O157:H7 can impact the health of consumers. Despite this, the pertinent mechanisms underlying...
Mon Oct 28, 2019 02:00
Microorganisms, Vol. 7, Pages 497: Bioremediation of Artificial Diesel-Contaminated Soil Using Bacterial Consortium Immobilized to Plasma-Pretreated Wood Waste Microorganisms doi: 10.3390/microorganisms7110497 Authors: Ravit Farber Alona Rosenberg Shmuel Rozenfeld Gabi Benet Rivka Cahan Bioaugmentation is a bioremediation option based on increasing the natural in-situ microbial population that possesses the ability to degrade the contaminating pollutant. In this study, a...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3886: Recent Advances in the Discovery of Novel Antiprotozoal Agents Molecules doi: 10.3390/molecules24213886 Authors: Lee Kim Hayat Shin Parasitic diseases have serious health, social, and economic impacts, especially in the tropical regions of the world. Diseases caused by protozoan parasites are responsible for considerable mortality and morbidity, affecting more than 500 million people worldwide. Globally, the burden of protozoan diseases is...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3887: New Molecular Insights into the Inhibition of Dipeptidyl Peptidase-4 by Natural Cyclic Peptide Oxytocin Molecules doi: 10.3390/molecules24213887 Authors: Chittepu Kalhotra Osorio-Gallardo Jiménez-Martínez Torre Gallardo-Velazquez Osorio-Revilla Protease inhibition has led to treating many diseases and has been successful in producing many commercial drugs by pharmaceutical companies. Among many proteases, serine protease has been...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3884: Experimental Design Modeling of the Effect of Hexagonal Wurtzite—ZnO Synthesis Conditions on Its Characteristics and Performance as a Cationic and Anionic Adsorbent Molecules doi: 10.3390/molecules24213884 Authors: Khalaf Da’na Al-Amer Hessien Surface composite design was used to study the effect of the ZnO synthesis conditions on its adsorption of methyl orange (MO) and methylene blue (MB). The ZnO was prepared via hydrothermal treatment...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3883: Carbohydrate-Based Chiral Iodoarene Catalysts: A Survey through the Development of an Improved Catalyst Design Molecules doi: 10.3390/molecules24213883 Authors: Imrich Biehler Maichle-Mössmer Ziegler Iodoarene catalysts can be applied in versatile reactions, for instance in the construction of complex chiral molecules via dearomatization of simple aromatic compounds. Recently, we reported the synthesis of the first carbohydrate-based chiral...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3881: Praziquantel-Solid Lipid Nanoparticles Produced by Supercritical Carbon Dioxide Extraction: Physicochemical Characterization, Release Profile, and Cytotoxicity Molecules doi: 10.3390/molecules24213881 Authors: Andrade Oliveira Chaud Alves Nery da Silva Gonsalves Nunes Corrêa Amaral Sanchez-Lopez Souto Severino Solid lipid nanoparticles (SLNs) can be produced by various methods, but most of them are difficult...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3882: Electrical Characteristics and Reliability of Nitrogen-Stuffed Porous Low-k SiOCH/Mn2O3-xN/Cu Integration Molecules doi: 10.3390/molecules24213882 Authors: Cheng Lin Lee Chen Fang In our previous study, a novel barrier processing on a porous low-dielectric constant (low-k) film was developed: an ultrathin Mn oxide on a nitrogen-stuffed porous carbon-doped organosilica film (p-SiOCH(N)) as a barrier of the Cu film was fabricated. To form...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3885: Soft Microwave Pretreatment to Extract P-Hydroxycinnamic Acids from Grass Stalks Molecules doi: 10.3390/molecules24213885 Authors: Bichot Lerosty Geirnaert Méchin Carrère Bernet Delgenès García-Bernet The aim of this article is to provide an analysis of microwave effects on ferulic and coumaric acids (FA and CA, respectively) extraction from grass biomass (corn stalks and miscanthus). Microwave pretreatment using various solvents...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3880: Fingerprinting, Antimicrobial, Antioxidant, Anticancer, Cyclooxygenase and Metabolic Enzymes Inhibitory Characteristic Evaluations of Stachys viticina Boiss. Essential Oil Molecules doi: 10.3390/molecules24213880 Authors: Nidal Jaradat Nawaf Al-Maharik The present study aimed to identify the chemical constituents and to assess the in-vitro, antimicrobial, anticancer, antioxidant, metabolic enzymes and cyclooxygenase (COX) inhibitory properties of essential...
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3879: Impact of Nitrogen Fertilizer Levels on Metabolite Profiling of the Lycium barbarum L. Fruit Molecules doi: 10.3390/molecules24213879 Authors: Zhigang Shi Feng Wei Ru Wan Yunxiang Li Yajun Wang Wei An Ken Qin Guoli Dai Youlong Cao Jiayue Feng The yield and quality of goji (Lycium barbarum L.) fruit are heavily dependent on fertilizer, especially the availability of nitrogen, phosphorus, and potassium (N, P, and K, respectively)....
Mon Oct 28, 2019 02:00
Molecules, Vol. 24, Pages 3878: Characterization and Antioxidant Activity of Essential Oil of Four Sympatric Orchid Species Molecules doi: 10.3390/molecules24213878 Authors: Francesco Saverio Robustelli della Cuna Jacopo Calevo Elia Bari Annalisa Giovannini Cinzia Boselli Aldo Tava The volatile fractions from fresh inflorescences of naturally growing orchids Anacamptis coriophora (L.) R. M. Bateman, Pridgeon & M. W. Chase subsp. fragrans (Pollini), Anacamptis pyramidalis...
Mon Oct 28, 2019 02:00
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