Publication date: Available online 20 October 2019Source: American Journal of OtolaryngologyAuthor(s): Herbert Silverstein, Brian Kellermeyer, Ulyseius MartinezAbstractObjectiveA minimally invasive surgery developed by the senior author has previously been reported to significantly improve sound tolerance after surgery. This report compares the new versus original surgical technique used and long-term results of all patients who have undergone minimally invasive surgery for hyperacusis.Study designA...
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Abstract Purpose To compare the surgical and audiological outcomes with two perimodiolar electrode arrays (Nucleus 512-Contour Advance® y Nucleus 532-Slim Perimodiolar®) and a straight electrode array (Nucleus 422/522). Methods Patients were retrospectively selected from our cochlear implant program database. Only patients with a history of bilateral, sensorineural...
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Abstract Bacterial Extracellular Vesicles (EVs) are bilayered lipid membrane structures, bearing integral proteins and able to carry diverse cargo outside the cell to distant sites. In microorganisms, EVs carry several types of molecules: proteins, glycoproteins, mRNAs, and small RNA species, as mammalian EVs do, but also carbohydrates. Studying EVs opens a whole new world of possibilities to better understand the interplay between host and bacteria crosstalks, although there are still many questions...
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Abstract Background Human papillomavirus (HPV)‐positive oropharyngeal squamous cell carcinoma (OPSCC) is associated with better tumor‐response rates and survival outcomes. However, in some geographic regions, the impact of HPV infection on prognosis remains unclear. The aim of this study was to describe the patterns of recurrence and survival among patients treated for OPSCC in a geographic region with a reported low prevalence of HPV‐related OPSCC. Methods We retrospectively evaluated...
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Related ArticlesPrediction of aspiration in dysphagia using logistic regression: oral intake and self-evaluation. Eur Arch Otorhinolaryngol. 2019 Oct 19;: Authors: Heijnen BJ, Böhringer S, Speyer R Abstract OBJECTIVES: Oropharyngeal dysphagia (OD) has a major influence on health in general and health-related quality of life (HR-QoL) in particular. The gold standard assessments for OD, especially for aspiration in OD, are fiberoptic endoscopic evaluation...
Mon Oct 21, 2019 15:04
Related ArticlesAssociation between serum vitamin D levels and benign paroxysmal positional vertigo: a systematic review and meta-analysis of observational studies. Eur Arch Otorhinolaryngol. 2019 Oct 19;: Authors: Yang B, Lu Y, Xing D, Zhong W, Tang Q, Liu J, Yang X Abstract OBJECTIVE: Benign paroxysmal positional vertigo (BPPV) was the most common neuro-otological disorder manifests as recurrent positional vertigo, but its risk factors are elusive....
Mon Oct 21, 2019 15:04
Related ArticlesAn improved method for examining fat taste. Eur Arch Otorhinolaryngol. 2019 Oct 19;: Authors: Smutzer G, Alvarado JJ, Haggard DZ, Solomon MT, Czapp D Abstract PURPOSE: The detection of fat taste in humans requires the delivery of hydrophobic stimuli to the oral cavity. Due to their low solubility in water, these fat taste stimuli are difficult to administer to test subjects by means of aqueous solutions or dispersions. These hydrophobic...
Mon Oct 21, 2019 15:04
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J Neurol Surg BDOI: 10.1055/s-0039-1697039 Objective Cystic vestibular schwannomas (CVSs) are anecdotally believed to have worse clinical and tumor-control outcomes than solid vestibular schwannomas (SVSs); however, no data have been reported to support this belief. In this study, we characterize the clinical outcomes of patients with CVSs versus those with SVSs. Design This is a retrospective review of prospectively collected data. Setting This study is set at...
J Neurol Surg BDOI: 10.1055/s-0039-1700498 Purpose Despite multidisciplinary care being commonly recommended, there remains limited evidence supporting its benefits in pituitary disease management. This study aimed to assess the impact of multidisciplinary care in pituitary surgery. Methods A retrospective cohort study was performed comparing pituitary surgery outcomes among consecutive patients within a quaternary referral center in 5 years before and after introduction of...
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Electrical stimulation of the recurrent laryngeal nerve is a safe and promising therapeutic approach with the potentiality to overcome the shortcomings of conventional surgical glottal enlargement. Although aberrant or synkinetic reinnervation is commonly considered an unfavorable condition, particularly for recovery of vocal fold movement, its presence is essential to ensure the effective clinical performance of laryngeal pacemakers. Thus, the effective selection of patients who can profit from...
Auditory brainstem implants (ABIs) stimulate the auditory system at the cochlear nucleus, bypassing the peripheral auditory system including the auditory nerve. They are used in patients who are not cochlear implant candidates. Current criteria for use in the United States are neurofibromatosis type 2 patients 12 years or older undergoing first- or second-side vestibular schwannoma removal. However, there are other nontumor conditions in which patients may benefit from an ABI, such as bilateral cochlear...
The current literature on peripheral cranial nerve stimulation for the purpose of achieving therapeutic effects via altering brain activity is reviewed. Vagus nerve stimulation, which is approved for use in refractory epilepsy, is the most extensively studied cranial nerve stimulator that has direct impact on the central nervous system. Despite the recognized central effects of peripheral cranial nerve stimulation, the mechanism of action for all indications remains incompletely understood. Further...
This overview of ethical and social issues pertaining to cranial nerve implants covers informed consent; risk-benefit assessments; security against unauthorized reprogramming or privacy intrusion; explantation; psychological side effects; equity and social distribution, cultural effects, for instance, on the deaf subculture; enhancement; and research ethics.
As otolaryngologists, we specialize in the management of various individual organs within an anatomical region. This provides our specialty with a unique opportunity to address a breadth of disorders that are largely related to the special senses and often involve specific input from individual cranial nerves. As such, management of these disorders can be challenging because of the sensitive information being relayed and the complexities involved in cranial nerve signaling. When medical options fail...
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Objective Frailty has emerged as an important determinant of many health outcomes across various surgical specialties. We examined the published literature reporting on frailty as a predictor of perioperative outcomes in head and neck cancer (HNC) surgery. Study Design Narrative review with limited electronic database search and cross‐referencing of included studies. Methods PubMed was searched from inception until June 2019 to capture studies evaluating an association between frailty...
Objectives/Hypothesis Demonstration of voice improvement and long‐term stability following nonselective unilateral laryngeal reinnervation (ULR) in patients with unilateral vocal fold paralysis (UVFP) and severe denervation. A subgroup of patients on whom ULR was performed as a salvage technique following unsuccessful medialization was analyzed separately. Study Design Prospective cohort study. Methods The ansa cervicalis–recurrent laryngeal nerve anastomosis technique was performed...
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