BACKGROUND As trauma is one of the leading causes of death worldwide, there is great potential for reducing mortality in trauma patients. However, there is continuing controversy over the benefit of deploying emergency medical systems (EMS) physicians in the prehospital setting. The objective of this systematic review and meta-analysis is to assess how out-of-hospital hospital management of severely injured patients by EMS teams with and without physicians affects mortality. METHODS PubMed...
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Publication date: January 2020Source: Journal of Environmental Radioactivity, Volume 211Author(s): Timothy E. Payne, Jennifer J. Harrison, Dioni I. Cendon, M. Josick Comarmond, Stuart Hankin, Catherine E. Hughes, Mathew P. Johansen, Andrew Kinsela, Lida Mokhber Shahin, Adella Silitonga, Sangeeth Thiruvoth, Kerry L. WilsherAbstractThis paper examines the distributions of several anthropogenic radionuclides (239+240Pu, 241Am, 137Cs, 90Sr, 60Co and 3H) at a legacy trench disposal site in eastern Australia....
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Publication date: Available online 26 October 2019Source: The Journal of Emergency MedicineAuthor(s): W. Frank Peacock, James C. Grotta, Thorsten SteinerAbstractBackgroundIdarucizumab is a humanized, monoclonal antibody fragment used specifically to reverse the anticoagulant effects of dabigatran.Case ReportsWe discuss 4 cases of patients who were treated with idarucizumab to reverse dabigatran before early/emergency surgery. Two of the patients had subdural hematomas, 1 had a splenic laceration,...
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When it comes to coverage of stem cell research in the media, science news can both be cool, but also surprising. Some of the more interesting publications don’t always draw news coverage too. This post is a list of recent [...] The post Recommended reads: stem cell pubs plus science news appeared first on The Niche.
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Publication date: Available online 26 October 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Adrian Y.S. Lee, Anthony J.F. Smith, Matthew Krummenacher, Tiffany L. Hughes
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SUNDAY, Oct. 27, 2019 -- Weight-loss surgery should be more widely used to treat severely obese children and teens, a leading pediatricians' group says. Severe obesity is a serious and worsening public health crisis among U.S. youngsters, and...
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Publication date: Available online 26 October 2019Source: Oral OncologyAuthor(s): Aakruti Shah, Rajiv S. Desai, Pankaj Shirsat, Shivani Bansal, Pooja Prasad
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Abstract Background Spastic paraplegia, optic atrophy and neuropathy (Spoan syndrome) is an autosomal recessive disease with approximately 70 cases recorded in Brazil and Egypt. Methods This is a prospective longitudinal study performed with 47 patients affected with Spoan syndrome of seven communities of Rio Grande do Norte (Brazil) to investigate...
Abstract Background A persistent trigeminal artery (PTA) is a non-involuted embryonic vessel that connects the cavernous part of the internal carotid artery with the posterior circulation. In the adult it is associated with multiple pathological conditions including trigeminal neuralgia, ophthalmoplegia, hypopituitarism, intracavernous fistula, brain aneurysms and posterior circulation strokes. The latter may occur through steal...
Abstract Background Many patients with chronic illness have sexual dysfunction that may be related to the condition itself, drug side effects, emotional sequel, or a combination of those factors. Patients with epilepsy are no exception. Men and women with epilepsy are frequently complaining sexual dysfunction and they appear to have a higher incidence of sexual dysfunction than peoples with other chronic neurologic illness. These...
Abstract Background We encountered two unrelated individuals suffering from neurological disorders, including epilepsy and scoliosis. Case presentation Whole-exome sequencing identified the same recurrent, de novo, pathogenic variant in NUS1 [NM_138459.4:c.691 + 1C > A] in both individuals. This variant is located in the conserved cis-prenyltransferase...
Abstract Background Demyelinating central nervous system diseases include several disorders that multiple sclerosis (MS) is identified as the most common among them. Ocular movement disturbances are a typical presentation in MS patients where lesions affect the complex and interconnected pathways involved in eye motion. Centers for gaze control are located in the pons primarily; therefore, lesions involving these centers can be presented...
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AbstractImpulsivity in Parkinson’s disease may be mediated by faulty evaluation of rewards or the failure to inhibit inappropriate choices. Despite prior work suggesting that distinct neural networks underlie these cognitive operations, there has been little study of these networks in Parkinson’s disease, and their relationship to inter-individual differences in impulsivity. High-resolution diffusion MRI data were acquired from 57 individuals with Parkinson’s disease (19 females, mean age 62, mean...
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Publication date: December 2019Source: Journal of Anthropological Archaeology, Volume 56Author(s): Marta Portillo, Aroa García-Suárez, Arkadiusz Klimowicz, Marek Z. Barański, Wendy MatthewsAbstractOver the last few decades a variety of geoarchaeological methods and ethnoarchaeological and experimental approaches have demonstrated the fundamental importance of animal dung deposits for reconstructing past human life-ways. Through simultaneous examination in micromorphological thin-section and integrated...
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Background: Previous data suggest that the incidence of hypoparathyroidism after surgery for Graves disease (GD) is lower after subtotal thyroidectomy compared to total thyroidectomy (TT). The present study evaluated the incidence of postoperative hypoparathyroidism after near-total (NTT) versus TT in GD. Methods/Design: In a multicenter prospective randomized controlled clinical trial, patients with GD were randomized intraoperatively to NTT or TT. Primary endpoint was the incidence of transient...
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Abstract Anxiety disorders are the most frequent mental disorders and are more prevalent in the female population. Up to date, an involvement of guanylate cyclase A and B in anxiety‐like behavior has been suggested. In this study, we showed an expression of guanylate cyclase C (GC‐C) in the amygdala which is regulated by feeding. Therefore, we further investigated sex differences of GC‐C effects on anxiety levels with special attention to female estrous cycle and feeding. The effects of estrous...
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Publication date: Available online 26 October 2019Source: Allergology InternationalAuthor(s): Izumi Kishimoto, Chuyen Thi Hong Nguyen, Naotomo Kambe, Nhung Thi My Ly, Yoko Ueki, Ikuko Ueda-Hayakawa, Hiroyuki Okamoto
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Publication date: Available online 26 October 2019Source: Atmospheric EnvironmentAuthor(s): Xingchuan Yang, Chuanfeng Zhao, Nana Luo, Wenji Zhao, Wenzhong Shi, Xing YanAbstractHimawari-8 aerosol products are useful for forecasting weather, environmental monitoring, and climate change research. In 2018, after receiving much attention from researchers, the Himawari-8 Level2 (L2) aerosol retrieval algorithm was updated from Version 1.0 (V1.0) to Version 2.1 (V2.1). Although previous studies have examined...
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Publication date: Available online 26 October 2019Source: Clinical TherapeuticsAuthor(s): Jessica Mason, Alyssa Kiel, Alexis White, Collin M. Clark, Bethany A. Wattengel, John A. Sellick, Kari A. MergenhagenAbstractPurposeThe most commonly reported medication allergies in the United States involve beta-lactam antibiotics, creating an important consideration for prescribers when choosing optimal treatment of infections. Currently, few data exist on outpatient prescribing patterns in response to patients...
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To assess the effect of comprehensive sexuality education on the comprehensive knowledge and attitude to condom use among first-year students at Arba Minch University.
The present study aims to investigate the etiology, clinical profile and resistance pattern of the isolated pathogens in Nepalese adults with acute gastroenteritis. This cross-sectional study was conducted at ...
As adolescence is a stage in which human beings face once throughout a lifetime and it is the experimental period for this reason risky sexual behavior is common among young people, and it has several sexual a...
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Publication date: Available online 26 October 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Patrick Coughlin
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Publication date: Available online 26 October 2019Source: Human PathologyAuthor(s): Cherise Meyerson, Bita V. NainiSummaryDrug-induced liver injury (DILI) is a challenging and constantly changing field. The pathologist plays a key role in interpreting liver biopsies by classifying the pattern of injury, grading the severity of injury, and evaluating for other possible causes. Reports of iatrogenic liver injury are reviewed here with a focus on total parenteral nutrition (TPN) [i.e., intestinal failure-associated...
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Loss‐of‐function mutations in CEP112 were identified from two infertile patients with acephalic spermatozoa. The nonsense mutation c.496C>T produces a truncated CEP112 protein and the bi‐allelic mutations c.2074C>T and c.2104C>T may affect the coiled‐coil domain of CEP112. The expression of CEP112 protein level was reduced significantly in the patients’ spermatozoa. Abstract Acephalic spermatozoa, characterized by the headless sperm in the ejaculate, is a rare type of teratozoospermia....
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Abstract Aim To evaluate the influence of the Metal Artefact Reduction tool (MAR) in the diagnosis of fractured instruments in root canals of extracted mandibular molars, with or without root canal fillings. Methodology The root canals of 31 mandibular molars were divided into 4 groups: 1. the control group, without root fillings; 2. the fracture group, without fillings and with fractured files; 3. the fill group, with root filling; and 4. the fill/fracture group, root filled and with fractured...
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