- SIRPα expression delineates subsets of intratumoral monocyte/macrophages with different functional and prognostic impact in follicular lymphomaBlood Cancer Journal, Published online: 14 October 2019; doi:10.1038/s41408-019-0246-0SIRPα expression delineates subsets of intratumoral monocyte/macrophages with different functional and prognostic impact in follicular lymphoma
- Journal of Oral Pathology & Medicine
- Cytokines Secreted by Arecoline Activate Fibroblasts that Affect the Balance of TH17 and TregAbstract Background Oral submucous fibrosis (OSF) is a chronic progressive oral disease with cancerous tendency. Arecoline plays an important role in the pathogenesis of OSF. Fibroblasts (FBs) are the primary cells involved in the pathogenesis of OSF. There is a change in CD4+IL‐17+ helper T cells (Th17) and CD4+CD25+Foxp3+ regulatory T cells (Treg) in OSF patients, but the molecular mechanisms of are not clearly understood. In this work, we
- Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
- Surrogate Markers for High Risk Human Papillomavirus Infection in Oral Epithelial Dysplasia: A Comparison of p16, Ki-67 and ProExCTo determine the utility of surrogate markers of human papillomavirus (HPV) infection in the diagnosis of HPV associated oral epithelial dysplasia (OED).
- Modified in-continuity resection is advantageous in both prognosis and postoperative complications as a new surgical management for oral tongue cancerTo explore the application value of modified in-continuity resection compared with traditional in-continuity resection and discontinuous resection for patients with cT2N0M0 oral tongue squamous cell carcinoma.
- pubmed: "oral oncol"[jour]
- MYB-activated models for testing therapeutic agents in adenoid cystic carcinoma.Related ArticlesMYB-activated models for testing therapeutic agents in adenoid cystic carcinoma. Oral Oncol. 2019 Oct 10;98:147-155 Authors: Jiang Y, Gao R, Cao C, Forbes L, Li J, Freeberg S, Fredenburg KM, Justice JM, Silver NL, Wu L, Varma S, West R, Licht JD, Zajac-Kaye M, Kentsis A, Kaye FJ Abstract OBJECTIVE: There are no effective systemic therapies for adenoid cystic cancer (ACC) and lack of t
- FPL : Last 10 articles
- One-Year Follow-Up of a Vocal Hygiene Program for School-Age ChildrenObjective: This study investigated the effects of a school-based vocal hygiene education program “Green Voice for School” on promoting knowledge of healthy voice use for primary school students. Methods: Thirty-nine grade 4 and 5 students from local primary schools participated in the “Green Voice for School” program. Students received 6 weekly vocal hygiene training sessions with the aim of enhancing their voice care knowledge. Their voice care
- British Journal of Oral and Maxillofacial Surgery
- Changes in the position of the condyle after bilateral sagittal split ramus osteotomy in patients with mandibular retrusion and protrusion: a new condyle: fossa matching conceptThe purpose of this study was to compare the condylar positional changes after bilateral sagittal split ramus osteotomy (BSSRO) in patients with mandibular retrusion and those with mandibular prognathism. We also studied the correlation between the degree of matching of the condyle and fossa, and condylar displacement. Thirty patients with mandibular retrusion (n=11) or mandibular prognathism (n=19) who underwent BSSRO were included. The condylar
- pubmed: "oral surg oral med ...
- Expression and clinicopathologic significance of coxsackie-adenovirus receptor in oral squamous cell carcinoma.Related ArticlesExpression and clinicopathologic significance of coxsackie-adenovirus receptor in oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Sep 02;: Authors: Chen DR, Xiao Y, Li H, Wu CC, Yang LL, Yang QC, Yang SC, Zhou JJ, Sun ZJ Abstract OBJECTIVE: This study aimed to explore the relationship between the expression of the coxsackie-adenovirus receptor (CAR) in o
- Histologic analysis of medication-related osteonecrosis of the jaw compared with antiresorptive-exposed bone and other infectious, inflammatory, and necrotic jaw diseases.Related ArticlesHistologic analysis of medication-related osteonecrosis of the jaw compared with antiresorptive-exposed bone and other infectious, inflammatory, and necrotic jaw diseases. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Sep 03;: Authors: Yuan A, Munz A, Reinert S, Hoefert S Abstract OBJECTIVE: This study characterized histologic features of medication-related osteonecrosis of the jaw
- Microcephalic osteodyplastic primordial dwarfism type II: case report with unique oral findings and a new mutation in the pericentrin gene.Related ArticlesMicrocephalic osteodyplastic primordial dwarfism type II: case report with unique oral findings and a new mutation in the pericentrin gene. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Sep 03;: Authors: Ghosh S, Garg M, Gupta S, Choudhary M, Chandra M Abstract OBJECTIVE: Microcephalic osteodysplastic dwarfism (MOPD) type II (OMIM 210720) is a rare autosomal recessive form of primo
- Tumor depth of invasion versus tumor thickness in guiding regional nodal treatment in early oral tongue squamous cell carcinoma.Related ArticlesTumor depth of invasion versus tumor thickness in guiding regional nodal treatment in early oral tongue squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Aug 19;: Authors: Liu B, Amaratunga R, Veness M, Wong E, Abdul-Razak M, Coleman H, Gebski V, Sundaresan P Abstract OBJECTIVES: Tumor thickness (TT) and tumor depth of invasion (DOI) correlate with the risk of
- CTNNB1 and APC mutations in odontogenic carcinoma with dentinoid.Related ArticlesCTNNB1 and APC mutations in odontogenic carcinoma with dentinoid. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Sep 03;: Authors: Gondak RO, Mariano FV, de Sousa SF, Siqueira EC, Díaz KP, Martins LAL, Altemani A, Mosqueda-Taylor A, Gomez RS, Gomes CC Abstract The purpose of the present study is to report 2 cases of odontogenic carcinoma with dentinoid, a rare low-grade odontogenic
- Latest Results for Investigational New Drugs
- Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3Summary The Janus kinase-signal transducer and activator of transcription (JAK-STAT) signaling pathway plays a vital role in immunity, cell division, cell death and tumor formation. Disrupted JAK-STAT signaling may lead to various diseases, especially cancer and immune disorders. Because of its importance, this signaling pathway has received significant attention from the pharmaceutical and biotechnology industries as a therape
- Journal of Clinical Pharmacy and Therapeutics
- Potential risks of rare serious adverse effects related to long‐term use of bisphosphonates: An overview of systematic reviewsThis overview of systematic reviews provided a comprehensive assessment on the risk of rare serious adverse effects of long term use of BPs for the treatment of osteoporosis. And it indicated that long‐term use of BPs significantly increased the risk of atypical fracture, ONJ and prolonged union time. Abstract What is known and objective There have been concerns about a potential link between long‐term use of bisphosphonates (BPs) for the t
- Latest Results for European Journal of Clinical Microbiology
- Latest Results for International Journal of Clinical Oncology
- FDG-PET reflects tumor viability on SUV in colorectal cancer liver metastasisAbstract Background Liver resection is the most effective procedure for colorectal cancer liver metastasis (CRLM); however, early recurrence is an important problem that affects the postoperative prognoses of patients with CRLM. We previously suggested a therapeutic algorithm for CRLM using fluorodeoxyglucose-positron emission tomography (FDG-PET) and revealed the applicability of FDG-
- Investigative Radiology - Current Issue
- Transcranial Shear Wave Elastography of Neonatal and Infant Brains for Quantitative Evaluation of Increased Intracranial PressureObjectives Increased intracranial pressure (ICP) in neonates and infants is a severe disease state that requires adequate diagnosis and, depending on the clinical situation and whether it is increasing, a rapid and efficient therapy. Clinical evaluation, B-mode ultrasound, and Doppler ultrasound give rise to a basic noninvasive diagnosis of increased ICP. The purpose of this prospective study was 2-fold: first, to analyze the technical feasibi
- Modulating Diffusion-Weighted Magnetic Resonance Imaging for Screening in Oncologic Tertiary Prevention: A Prospective Ex Vivo and In Vivo StudyIntroduction Diffusion-weighted imaging (DWI) is an important part of oncological magnetic resonance imaging (MRI) examinations, especially for tertiary cancer prevention in terms of early detection of recurrent disease. However, abdominal studies can be challenged by motion artifacts, poor signal-to-noise ratios, and visibility of retroperitoneal structures, which necessitates sequence optimization depending on the investigated region. This s
- Magnetization Transfer Imaging Is Unaffected by Decreases in Renal Perfusion in SwineObjectives Multiparametric renal magnetic resonance imaging (MRI), including diffusion-weighted imaging, magnetic resonance elastography, and magnetization transfer imaging (MTI), is valuable in the noninvasive assessment of renal fibrosis. However, hemodynamic changes in diseased kidneys may impede their ability to measure renal fibrosis. Because MTI assesses directly tissue content of macromolecules, we test the hypothesis that MTI would be
- Ultrasound Time-Harmonic Elastography of the Aorta: Effect of Age and Hypertension on Aortic StiffnessObjectives The aim of this study was to investigate ultrasound time-harmonic elastography for quantifying aortic stiffness in vivo in the context of aging and arterial hypertension. Materials and Methods Seventy-four participants (50 healthy participants and 24 participants with long-standing hypertension) were prospectively included between January 2018 and October 2018, and underwent ultrasound time-harmonic elastography of the upper ab
- Measuring Dynamic CT Perfusion Based on Time-Resolved Quantitative DECT Iodine Maps: Comparison to Conventional Perfusion at 80 kVp for Pancreatic CarcinomaObjectives Using dual-energy computed tomography (DECT) for quantifying iodine content after injection of contrast agent could provide a quantitative basis for dynamic computed tomography (CT) perfusion measurements by means of established mathematical models of contrast agent kinetics, thus improving results by combining the strength of both techniques, which was investigated in this study. Materials and Methods A dynamic DECT acquisitio
- Three Tesla 3D High-Resolution Vessel Wall MRI of the Orbit may Differentiate Arteritic From Nonarteritic Anterior Ischemic Optic NeuropathyBackground Anterior ischemic optic neuropathy (AION) is the most common cause of acute optic neuropathy in older patients. Distinguishing between arteritic AION (A-AION) and nonarteritic (NA-AION) is paramount for improved patient management. Purpose The aim of this study was to evaluate 3-dimensional high-resolution vessel wall (HR-VW) magnetic resonance imaging (MRI) at 3 T to discriminate A-AION from NA-AION. Materials and Methods
- Tumor Contrast Enhancement and Whole-Body Elimination of the Manganese-Based Magnetic Resonance Imaging Contrast Agent Mn-PyC3AObjectives The goals of this study were to compare the efficacy of the new manganese-based magnetic resonance imaging (MRI) contrast agent Mn-PyC3A to the commercial gadolinium-based agents Gd-DOTA and to Gd-EOB-DTPA to detect tumors in murine models of breast cancer and metastatic liver disease, respectively, and to quantify the fractional excretion and elimination of Mn-PyC3A in rats. Methods T1-weighted contrast-enhanced MRI with 0.1 m
- Free-Breathing Dynamic Contrast-Enhanced Imaging of the Upper Abdomen Using a Cartesian Compressed-Sensing Sequence With Hard-Gated and Motion-State-Resolved ReconstructionObjectives The aim of this study was to compare a compressed-sensing free-breathing VIBE (fbVIBE) with a conventional breath-hold VIBE (bhVIBE) for dynamic contrast-enhanced imaging of the upper abdomen. Materials and Methods In total, 70 datasets (bhVIBE, n = 30; fbVIBE n = 40; hard-gated [hg] reconstruction, n = 30; motion-state-resolved [mr] reconstruction, n = 10) were assessed by 2 experienced readers. Both sequences were performed o
- Journal of Endodontics
- Overexpression of Cyclophilin A in Human Periapical LesionsCyclophilin A (CypA) is a cytosolic protein involved in multiple biological functions, such as inflammation, tissue remodeling, tumorigenesis, and vascular diseases. Human periapical lesions are induced by bacterial infections. However, the expression of CypA in human periapical lesions remains unclear. This study aimed to investigate the presence of CypA in human periapical lesions and the possible association of CypA with angiogenesis, inflamma
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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Τρίτη 15 Οκτωβρίου 2019
- Journal of Oral Pathology & Medicine
- Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
- pubmed: "oral oncol"[jour]
- FPL : Last 10 articles
- British Journal of Oral and Maxillofacial Surgery
- pubmed: "oral surg oral med ...
- Latest Results for Investigational New Drugs
- Journal of Clinical Pharmacy and Therapeutics
- Latest Results for European Journal of Clinical Microbiology
- Latest Results for International Journal of Clinical Oncology
- Investigative Radiology - Current Issue
- Journal of Endodontics
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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00302841026182,
00306932607174,
alsfakia@gmail.com,
Anapafseos 5 Agios Nikolaos 72100 Crete Greece,
Medicine by Alexandros G. Sfakianakis,
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