Abstract Background Management of upper gastrointestinal leaks is challenging. A new potential treatment option for this complication is endoscopic suturing with the OverStitch system (Apollo Endosurgery, Texas, USA), which is today mainly used for endoscopic sleeve gastroplasty. The aim of this study was to analyze the efficacy and feasibility of this new treatment option in patients with leaks in the upper gastrointestinal tract. ...
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Abstract Background Few community urologists offer cancer patients the opportunity to participate in cancer clinical trials, despite national guidelines that recommend it, depriving an estimated 260,000 urological cancer patients of guideline-concordant care each year. Existing strategies to increase urologists’ offer of clinical trials are designed for resource-rich environments and are not feasible for many community urologists....
Abstract Background Adolescent social anxiety disorder (SAD) is common, impairing and persistent. There is a need to intervene early to avert its long-term consequences. Cognitive Therapy for SAD is the leading treatment for adults and shows promise for adolescents. However, given the scale of the problem of adolescent SAD and the limited availability of psychological therapists in child and adolescent mental health services, there...
Abstract Objective One of the most challenging parts of running clinical trials is recruiting enough participants. Our objective was to determine which recruitment strategies were effective in reaching specific subgroups. Study design and setting We assessed the efficacy and costs of the recruitment strategies used in the Assessing Outcomes...
Abstract Background Dizziness is a common complaint, and the symptom often persists, together with additional complaints. A treatment combining Vestibular Rehabilitation (VR) and Cognitive Behaviour Therapy (CBT) is suggested. However, further research is necessary to evaluate the efficacy of such an intervention. The objective of this paper is to present the design of a randomised controlled trial aiming at evaluating the efficacy...
Abstract Background Colorectal cancer is the fourth most commonly diagnosed cancer in the United States. Approximately 3–10% of the population has an increased risk for colorectal cancer due to family history and warrants more frequent or intensive screening. Yet, < 50% of that high-risk population receives guideline-concordant care. Systematic collection of family health history and decision support may improve guideline-concordant...
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Abstract Background To evaluate the safety and feasibility of selective occlusion of the hepatic artery and portal vein (SOAP) for staged hepatectomy (SOAPS) in patients with hepatocellular carcinoma (HCC) Methods From December 2014 to August 2018, 9 patients with unresectable HCC were chosen to undergo SOAPS. SOAP without liver partition was...
Abstract Background The coexistence of hematological malignancy with endometrial cancer is a rare phenomenon. We report a case of coexistence of endometrial cancer with follicular lymphoma which we suspected preoperatively and diagnosed during surgery by a multidisciplinary intraoperative assessment. Case presentation A 67-year-old woman was...
Abstract Background To explore whether a polypropylene mesh is suitable for application as a new material for testicular prostheses. Methods The data of 65 patients with advanced prostate cancer who underwent surgical castration in hospital were collected and analyzed. Patients who preferred to undergo traditional orchidectomy (n = 16) were...
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O Γκάντι είπε ότι όλοι οι άνθρωποι έχουν ένα ταλέντο, το οποίο αποκτούν μέσω της μόρφωσης ή της κληρονομιάς. Λόγω του ανεξάρτητου και εγωιστικού τρόπου ζωής που έχουν επιλέξει, πιστεύουμε ότι το ταλέντο μας ΑΝΗΚΕΙ και, συνεπώς το εκμεταλλευόμαστε για το προσωπικό μας όφελος και για την εκπλήρωση των δικών μας φιλοδοξιών. Ο Γκάντι πίστευε ότι οι άνθρωποι μπορούν να κάνουν μεγαλύτερο καλό αλλάζοντας απλώς τη συμπεριφορά τους και θεωρώντας ότι είναι Κηδεμόνες και όχι Ιδιοκτήτες του ταλέντου τους. Αυτή...
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The longest running study of its kind on the "Housing First" model has found that it significantly reduces homelessness over the long term compared to treatment as usual, according to a study published in The Lancet Psychiatry by scientists at the Centre for Addiction and Mental Health (CAMH) and St. Michael's Hospital.
Exposure to violence can negatively impact a person's physical and psychosocial health, according to two new studies co-authored by University of Chicago Medicine social epidemiologist Elizabeth L. Tung, MD.
Psychologists at Emory University have found that the human brain uses three distinct systems to perceive our environment—one for recognizing a place, another for navigating through that place and a third for navigating from one place to another.
Have you ever thought about how your brain works when you study? Knowing this may improve your ability to retain and recall information.
A new study from Nationwide Children's Hospital and the Central Ohio Poison Center found rates of suicide attempts by self-poisoning among youth and adolescents are higher in rural communities, higher during the academic school year and involve common medications found in many households.
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PURPOSE The purpose of this study was to investigate the effectiveness of sports compression tights in reducing muscle movement and activation during running. METHODS A total of 27 recreationally-active males were recruited across two separate studies. For study one, 13 participants (mean ± SD; 84.1 ± 9.4 kg, 22 ± 3 y) completed two 4-min treadmill running bouts (2 min at 12 km.h-1 and 15 km.h-1) under two conditions; a no-compression control (CON1) and compression (COMP). For study two,...
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The first human Lyme vaccine was pulled off the market nearly 20 years ago. A new effort faces lingering suspicions.Undark (Source: Medscape Allergy Headlines)
Some familiar skin allergens are turning up in unexpected places, report dermatologists, who say care teams should keep them on their radar.Medscape Medical News (Source: Medscape Allergy Headlines)
Influenza vaccination might not always prevent illness, but it reduces the severity and even prevents death, new research shows.Medscape Medical News (Source: Medscape Allergy Headlines)
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Discoveries by two Americans and a British researcher regarding how cells sense and adapt to oxygen offer key insights for treating cancers and heart and lung diseases.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
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Med Princ Pract
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Abstract Carotenoids are tetraterpene pigments that are distributed in photosynthetic bacteria, some species of archaea and fungi, algae, plants, and animals. About 850 naturally occurring carotenoids had been reported up until 2018. Photosynthetic bacteria, fungi, algae, and plants can synthesize carotenoids de novo. Carotenoids are essential pigments in photosynthetic organs along with chlorophylls. Carotenoids also act as photo-protectors, antioxidants, color attractants, and...
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Nature, Published online: 07 October 2019; doi:10.1038/d41586-019-03025-1The wonder material is on track to deliver on its commercial promise, a lab-made primordial soup yields RNA bases, and hooray! It’s the first Noble of 2019.
Nature, Published online: 07 October 2019; doi:10.1038/s41586-019-1632-2Carrier-resolved photo-Hall effect
Nature, Published online: 07 October 2019; doi:10.1038/d41586-019-02998-3Expanded genetic-testing raises concerns about privacy for those who are tested — and their families.
Nature, Published online: 07 October 2019; doi:10.1038/d41586-019-02999-2Carefully chosen questions prompt non-Muslims to assign less ‘collective blame’ to Muslims for violent attacks.
Nature, Published online: 07 October 2019; doi:10.1038/s41586-019-1630-4In a charge-density-wave Weyl semimetal, an axion is observed and identified as a sliding mode in the charge-density-wave phase characterized by anomalous magneto-electric transport effects.
Nature, Published online: 07 October 2019; doi:10.1038/d41586-019-02978-7Comprehensive study of mammals, birds, amphibians and reptiles finds that nearly one-fifth of vertebrates are bought and sold around the world.
Nature, Published online: 07 October 2019; doi:10.1038/d41586-019-02991-wThe legal habit still kills more than eight million people a year. Felicity Lawrence praises a history.
Nature, Published online: 07 October 2019; doi:10.1038/d41586-019-02963-0William Kaelin, Peter Ratcliffe and Gregg Semenza share the award for discoveries that are crucial for understanding diseases such as cancer.
Nature, Published online: 07 October 2019; doi:10.1038/d41586-019-02959-wTree-dwelling birds can land on perches that vary in size and texture. Force measurements and video-footage analysis now reveal that birds rely on rapid and robust adjustments of their toe pads and claws to land stably.
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