• JoVE: Journal of Visualized Experiments
• Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

  Here, we present protocols of high-intensity interval and moderate-intensity continuous exercise to observe the response of circulating cardiac troponin T (cTnT) concentration to acute exercise over 10 days. The information may assist with clinical interpretations of post-exercise cTnT elevation and guide the prescription of exercise.

  JoVE: Journal of Visualized Experiments

  Thu Oct 10, 2019 11:18
• Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking

  This method involves utilization of clinical diagnostic data for prostate cancer patients in order to guide sampling procedures, when biobanking tissue following radical prostatectomy. This overcomes issues with previously published methods around efficiency and availability of fresh tissue for a wider range of downstream applications.

  JoVE: Journal of Visualized Experiments

  Thu Oct 10, 2019 10:18
• Journal of the American Chemical Society: Latest Articles (ACS Publications)
• [ASAP] Complete Protection of O₂-Sensitive Catalysts in Thin Films

  Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b06790

  Journal of the American Chemical Society: Latest Articles (ACS Publications)

  Wed Oct 09, 2019 21:00
• [ASAP] Inhibition of Amyloid-ß Aggregation by Cobalt(III) Schiff Base Complexes: A Computational and Experimental Approach

  Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b06388

  Journal of the American Chemical Society: Latest Articles (ACS Publications)

  Wed Oct 09, 2019 21:00
• [ASAP] Direct Manipulation of Metal Imido Geometry: Key Principles to Enhance C–H Amination Efficacy

  Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b09015

  Journal of the American Chemical Society: Latest Articles (ACS Publications)

  Wed Oct 09, 2019 21:00
• [ASAP] Peroxide-Promoted Disassembly Reassembly of Zr-Polyoxocations

  Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b08627

  Journal of the American Chemical Society: Latest Articles (ACS Publications)

  Wed Oct 09, 2019 21:00
• [ASAP] Charge Storage Mechanisms of Single-Layer Graphene in Ionic Liquid

  Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07134

  Journal of the American Chemical Society: Latest Articles (ACS Publications)

  Wed Oct 09, 2019 21:00
• [ASAP] Photorelease of 2-Arachidonoylglycerol in Live Cells

  Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b05978

  Journal of the American Chemical Society: Latest Articles (ACS Publications)

  Wed Oct 09, 2019 21:00
• [ASAP] Quantitative Conformational Analysis of Functionally Important Electrostatic Interactions in the Intrinsically Disordered Region of Delta Subunit of Bacterial RNA Polymerase

  Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b07837

  Journal of the American Chemical Society: Latest Articles (ACS Publications)

  Wed Oct 09, 2019 21:00
• Journal of Voice
• Singing with Gesture: Acoustic and Perceptual Measures of Solo Singers

  The purpose of this investigation was to examine the potential effects of two singer gestures on performances of solo singers (N = 32). Participants sang two songs (“Over the Rainbow” with low, circular arm gesture and “Singin’ in the Rain” with pointing gesture) five times: Baseline (without singer gesture), three iterations of each song paired with a singer gesture, and a post-test (without singer gesture). This investigation measured acoustic

  Journal of Voice

  Wed Oct 09, 2019 17:00
• Medgadget
• Medtronic’s Tiny New InterStim Micro Neurostimulator Submitted to FDA

  Medtronic has filed for FDA approval for its InterStim Micro neurostimulator and the accompanying InterStim SureScan MRI leads. The rechargeable device delivers sacral neuromodulation therapy to treat conditions such as overactive bladder, fecal incontinence, unobstructed urinary retention, and urinary urge incontinence. Along with the InterStim Micro, the new leads allow patients with the implanted system to safely receive MRI scans, given certa

  Medgadget

  Thu Oct 10, 2019 09:48
• Low Power MRI Helps Image Lungs, Brings Costs Down

  Modern clinical MRIs usually have magnetic field strengths of 1.5 or 3.0 Tesla. These are pretty powerful magnets and it’s the reason that these devices are very expensive. While such strengths have been standard for a long time, the internal hardware and software beyond the magnets have been improving steadily. Now, researchers affiliated with the National Institutes of Health have worked with a team at Siemens to see what a modern MRI, o

  Medgadget

  Thu Oct 10, 2019 07:52
• Dexcom G6 Pro with Blinded Mode FDA Cleared

  Dexcom landed FDA clearance for its Dexcom G6 Pro continuous glucometry system. Intended to be used by medical professionals with their patients, it offers a novel “blinded” mode that allows physicians to hide live glucose readings from patients. Using this capability, doctors can review glucometry data and propose lifestyle changes to patients following an up-to 10 day test period. In the meantime, patients don’t have to worry about what their g

  Medgadget

  Thu Oct 10, 2019 06:10
• New Drug Capsule for Oral Delivery of Insulin, Protein-Based Drugs

  Most drugs are administered in pill form, but some have to be injected because they would otherwise be broken down by the gastrointestinal tract. This limitation mostly applies to protein-based drugs. Insulin, essentially a small protein (aka peptide), is by far the most injected medication in the world. It saves lives, but injections can be pretty brutal on many people with diabetes, particularly young children and elderly people. Now, re

  Medgadget

  Thu Oct 10, 2019 05:35
• Angewandte Chemie International Edition
• Expanding the Arsenal of PtIV Anticancer Agents; Multi‐action PtIV Anticancer Agents with Bioactive Ligands Possessing Hydroxyl Functional Group

  Most multi‐action PtIV prodrugs have bioactive ligands containing carboxylates. This is probably due to the ease of carboxylating the OH axial ligands and because following reduction, the active form of the agent is released. A major challenge is to expand the arsenal of bioactive ligands to include those without carboxylates. We describe a general approach for synthesis of PtIV prodrugs that release in their native form, molecules with OH groups

  Angewandte Chemie International Edition

  Thu Oct 10, 2019 09:40
• Ion‐Specific Assembly of Strong, Tough and Stiff Biofibers

  Designing engineering materials with high stiffness and high toughness is challenging as stiff materials tend to be brittle. Many biological materials realize this objective through multiscale (i.e., atomic‐ to macroscale) mechanisms that are extremely difficult to replicate in synthetic materials. Inspired from the architecture of such biological structures, we here present flow‐assisted organization and assembly of renewable native cellulose na

  Angewandte Chemie International Edition

  Thu Oct 10, 2019 06:35
• A Triazole‐Substituted Aryl Iodide with Omnipotent Reactivity in Enantioselective Oxidations

  A widely applicable triazole‐substituted chiral aryl iodide is described as catalyst for enantioselective oxidation reactions. The introduction of a substituent in ortho‐position to the iodide is key for its high reactivity and selectivity. Besides a robust and modular synthesis, the key advantage of this catalyst is the throughout excellent performance  in a plethora of mechanistically diverse enantioselective transformations such as spirocycliz

  Angewandte Chemie International Edition

  Thu Oct 10, 2019 06:11
• Iron‐Mediated Electrophilic Amination of Organozinc Halides using Organic Azides

  A wide range of alkyl‐, aryl‐ and heteroarylzinc halides have been aminated with highly functionalized alkyl, aryl and heterocyclic azides. The reaction proceeds smoothly at 50 °C within 1 h in the presence of FeCl3 (0.5 equiv) to furnish the corresponding secondary amines in good yields. This method was extended to peptidic azides, providing the arylated substrates under full retention configuration. To demonstrate the utility of this reaction,

  Angewandte Chemie International Edition

  Wed Oct 09, 2019 11:13
• Barcoding biological reactions with DNA‐functionalized vesicles

  Targeted vesicle fusion is a promising approach to selectively control interactions between vesicle compartments and would enable the initiation of biological reactions in complex aqueous environments. Here, we explore how two features of vesicle membranes, DNA tethers and phase‐segregated membranes, promote fusion between specific vesicle populations. We show that membrane phase‐segregation provides an energetic driver for membrane fusion that i

  Angewandte Chemie International Edition

  Wed Oct 09, 2019 09:44
• CDs‐in‐Matrix: Energy Transfer Enhanced Red Room Temperature Phosphorescence

  Luminescent carbon dots (CDs), especially afterglow CDs, are attractive for their promising applications in encryption, optoelectronics and bioimaging. However, there remains a challenge to achieve high‐efficiency longwave afterglows in CDs system. Here, we demonstrate a CDs‐matrix energy transfer (CMET) strategy to modulate the emissions of room temperature phosphorescence (RTP), especially achieve high efficiency red RTP emissions by embedding

  Angewandte Chemie International Edition

  Wed Oct 09, 2019 08:17
• Difluoro(aryl)(perfluoroalkyl)‐λ4‐sulfanes and Selanes: Missing Links of Trichloroisocyanuric Acid/Potassium Fluoride Chemistry

  The TCICA/KF approach to oxidative fluorination of heteroatoms has emerged as a surprisingly simple, safe, and versatile surrogate to classically challenging fluorination reactions. Although polyfluorination (or chlorofluorination) of diaryl disulfides, diaryl diselenides, diaryl ditellurides, aryl iodides, and aryl(perfluoroalkyl)tellanes has been described, the application of this TCICA/KF methodology to aryl(perfluoroalkyl)sulfanes and selanes

  Angewandte Chemie International Edition

  Wed Oct 09, 2019 08:14
• Photochemical Strain‐Release Driven Cyclobutylation of C(sp3)‐centered Radicals

  A new photoredox‐catalyzed decarboxylative radical addition approach to functionalized cyclobutanes is described. The reaction involves an unprecedented formal Giese‐type addition of C(sp3)‐centered radicals to highly strained bicyclo[1.1.0]butanes. The mild photoredox conditions, which make use of a readily available and bench stable phenyl sulfonyl bicyclo[1.1.0]butane, proved to be amenable to a diverse range of α‐amino and α‐oxy carboxylic ac

  Angewandte Chemie International Edition

  Wed Oct 09, 2019 06:43
• Radiation Oncology - Latest Articles
• Dose-volume analysis of predictors for acute anal toxicity after radiotherapy in prostate cancer patients

  This study aimed to evaluate the clinical and dosimetric factors predictive of acute anal toxicity (AAT) after radiotherapy in prostate cancer (PCa) patients with or without hemorrhoids.

  Radiation Oncology - Latest Articles

  Wed Oct 09, 2019 17:00
• Cortex
• The Tenacious Brain: How the Anterior Mid-Cingulate Contributes to Achieving Goals

  Publication date: Available online 9 October 2019Source: CortexAuthor(s): Alexandra Touroutoglou, Joseph Andreano, Bradford C. Dickerson, Lisa Feldman BarrettAbstractTenacity--persistence in the face of challenge--has received increasing attention, particularly because it contributes to better academic achievement, career opportunities and health outcomes. We review evidence from non-human primate neuroanatomy and structural and functional neuroi

  Cortex

  Thu Oct 10, 2019 03:46
• Analytical Chemistry
• [ASAP] Electropolymerization-Induced Positively Charged Phenothiazine Polymer Photoelectrode for Highly Sensitive Photoelectrochemical Biosensing

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03311

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Database-Assisted Globally Optimized Targeted Mass Spectrometry (dGOT-MS): Broad and Reliable Metabolomics Analysis with Enhanced Identification

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03107

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Electrodynamic Force Derived in-Channel Separation and Detection of Au Nanoparticles Using an Electrochemical AC Microfluidic Channel

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03953

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Solid-State Quantification of Cocrystals in Pharmaceutical Tablets Using Transmission Low-Frequency Raman Spectroscopy

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b01895

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Demonstration of a Human Color Vision Mimic in the Infrared

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03749

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Ultrahighly Efficient and Stable Fluorescent Gold Nanoclusters Coated with Screened Peptides of Unique Sequences for Effective Protein and Serum Discrimination

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03463

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Biomineralization-Driven Ion Gate in TiO₂ Nanochannel Arrays for Cell H₂S Sensing

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b03119

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Simple Colorimetric Chemosensor Array for Oxyanions: Quantitative Assay for Herbicide Glyphosate

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b02822

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Overcoming Multidrug-Resistance in Bacteria with a Two-Step Process to Repurpose and Recombine Established Drugs

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b02690

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• [ASAP] Real-Time and In-Situ Monitoring of H₂O₂ Release from Living Cells by a Stretchable Electrochemical Biosensor Based on Vertically Aligned Gold Nanowires

  Analytical ChemistryDOI: 10.1021/acs.analchem.9b02610

  Analytical Chemistry

  Wed Oct 09, 2019 21:00
• Clinical Oral Implants Research
• Implant prosthetic complications, fractures of the implant fixtures – Retrospective clinical study

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Clinical and radiographic outcomes of implants with same morphology and different connections, a RCT

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Histological comparison in alveolar ridge preservation between various bone grafting materials

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• All‐on‐4 immediate function concept

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Marginal bone response around preloaded dental implants – A histological investigation in rabbits

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Control of focal adhesion dynamics of osteoblast cells and fibroblast by surface characteristics of titanium chambers – An in vitro study

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Influence of bone defect shape in implant surface decontamination using a protocol of spraying by high pressure water associated or not to sodium bicarbonate‐ an in vitro study

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Type H blood vessels, do they influence bone regeneration guided by bone substitutes?

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00
• Prospective study of wide‐diameter implants – Survival rate and marginal bone loss

  Clinical Oral Implants Research

  Wed Sep 25, 2019 12:00