Τρίτη 8 Οκτωβρίου 2019


Antibodies blocking the PD-1 pathway provide a common denominator for cancer therapy
Date: Friday, 10 25, 2019; Speaker: Suzanne L. Topalian MD, Associate Director; Professor, Johns Hopkins University School of Medicine; Bldg 37; 2nd Floor Conference Rooms 2041& 2107 (Source: NIH Calendar of Events)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
MedWorm Cancer & Oncology Events
Mon Sep 30, 2019 23:09
The Peter Pan Syndrome: Oncohistones Stall Development in Pediatric Cancers
Date: Friday, 10 25, 2019; Speaker: Nada Jabado, Professor, Department of Pediatrics, McGill University Health Centre (MUHC); Building: Building 10 (Clinical Center); Lipsett Amphitheater; Videocast Event (Source: NIH Calendar of Events)
MedWorm Cancer & Oncology Events
Mon Sep 30, 2019 23:09
LncRNA PTCSC3 inhibits the proliferation, invasion and migration of cervical cancer cells via sponging miR-574-5p.
Related ArticlesLncRNA PTCSC3 inhibits the proliferation, invasion and migration of cervical cancer cells via sponging miR-574-5p. Clin Exp Pharmacol Physiol. 2019 Oct 06;: Authors: Tong R, Zhang J, Wang C, Li X, Yu T, Wang L Abstract Dysregulation of long non-coding RNA Papillary thyroid carcinoma susceptibility candidate 3 (lncRNA PTCSC3) has been found to correlate with various types of cancers. Quantitative RT-PCR showed a down-regulation of PTCSC3...
pubmed: cell cycle arrest
Mon Oct 07, 2019 14:45
Anti-tumor effects and associated molecular mechanisms of myricetin.
Related ArticlesAnti-tumor effects and associated molecular mechanisms of myricetin. Biomed Pharmacother. 2019 Oct 03;120:109506 Authors: Jiang M, Zhu M, Wang L, Yu S Abstract Myricetin (3, 5, 7, 3', 4', 5'-hexahydroxyflavone) is a natural flavonol compound found in a large variety of plants, including berries, oranges, grapes, herbs, teas, and wine. In the last decade, a convergence of evidence has demonstrated that myricetin has good biological activity...
pubmed: cell cycle arrest
Mon Oct 07, 2019 14:45
A potential role of cyclin-dependent kinase inhibitor 1 (p21/WAF1) in the pathogenesis of endometriosis: Directions for future research.
Related ArticlesA potential role of cyclin-dependent kinase inhibitor 1 (p21/WAF1) in the pathogenesis of endometriosis: Directions for future research. Med Hypotheses. 2019 Sep 30;133:109414 Authors: Zarkadoulas N, Pergialiotis V, Dimitroulis D, Stefanidis K, Verikokos C, Perrea DN, Kontzoglou K Abstract Endometriosis is a common gynecological disorder that affects approximately 6-10% of the female population impairing the quality of life of patients....
pubmed: cell cycle arrest
Mon Oct 07, 2019 14:45
Microwave synthesis of novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]chromene moieties: Induces cell cycle arrest and apoptosis in human cancer cells via dual inhibition of topoisomerase I and II.
Related ArticlesMicrowave synthesis of novel halogenated β-enaminonitriles linked 9-bromo-1H-benzo[f]chromene moieties: Induces cell cycle arrest and apoptosis in human cancer cells via dual inhibition of topoisomerase I and II. Bioorg Chem. 2019 Sep 20;93:103289 Authors: Fouda AM, Assiri MA, Mora A, Ali TE, Afifi TH, El-Agrody AM Abstract A novel series of halogenated β-enaminonitriles (4a-m), linked 9-bromo-1H-benzo[f]-hromene moieties, were synthesized...
pubmed: cell cycle arrest
Mon Oct 07, 2019 14:45
Design, synthesis and biological evaluation of some new 1,3,4-thiadiazine-thiourea derivatives as potential antitumor agents against non-small cell lung cancer cells.
Related ArticlesDesign, synthesis and biological evaluation of some new 1,3,4-thiadiazine-thiourea derivatives as potential antitumor agents against non-small cell lung cancer cells. Bioorg Chem. 2019 Sep 26;93:103323 Authors: Ragab FAF, Abdel-Aziz SA, Kamel M, Ouf AMA, Allam HA Abstract New 1,3,4-thiadiazine-thiourea derivatives have been synthesized. All the synthesized compounds were examined for in vitro cytotoxic activity against Non-Small Cell...
pubmed: cell cycle arrest
Mon Oct 07, 2019 14:45
The antiproliferative effect of spectinabilins from Streptomyces spectabilis on hepatocellular carcinoma cells in vitro and in vivo.
Related ArticlesThe antiproliferative effect of spectinabilins from Streptomyces spectabilis on hepatocellular carcinoma cells in vitro and in vivo. Bioorg Chem. 2019 Sep 24;93:103311 Authors: Gao X, Yao H, Mu Y, Guan P, Li G, Lin B, Jiang Y, Han L, Huang X, Jiang C Abstract Spectinabilin (1), spectinabilin derivative (2), and a new analogue, 2-demethyl-spectinabilin (3) were isolated from the fermentation broth of a soil-borne Streptomyces spectabilis...
pubmed: cell cycle arrest
Mon Oct 07, 2019 14:45
Autoimmune Limbic Encephalitis in a Patient with Acute Encephalopathy and Hyponatremia
Acute encephalopathy is a common clinical presentation for hospital admissions. Autoimmune encephalitis is a rare cause of encephalopathy which has increasingly been recognized over the last decade. The detection of various neuronal antibodies has helped diagnose these syndromes, but they have limited availability, mostly in the developed countries. We present a case of a middle-aged female presenting with memory impairment, gait disturbances, and hyponatremia. A clinical diagnosis of autoimmune...
Case Reports in Medicine
Mon Oct 07, 2019 11:05
Real-time control of respiratory motion: Beyond radiation therapy.
Related ArticlesReal-time control of respiratory motion: Beyond radiation therapy. Phys Med. 2019 Oct 03;66:104-112 Authors: Cavedon C Abstract Motion management in radiation oncology is an important aspect of modern treatment planning and delivery. Special attention has been paid to control respiratory motion in recent years. However, other medical procedures related to both diagnosis and treatment are likely to benefit from the explicit control of...
pubmed: future oncology
Mon Oct 07, 2019 14:37
Trends in adherence to thromboprophylaxis guideline in patients undergoing radical cystectomy.
Related ArticlesTrends in adherence to thromboprophylaxis guideline in patients undergoing radical cystectomy. Urology. 2019 Oct 03;: Authors: Tully KH, Krimphove MJ, Reese SW, Kibel AS, Noldus J, Krasnow RE, Trinh QD, Sonpavde GP, Chang SL, Mossanen M Abstract OBJECTIVE: To examine the use of in-hospital pharmacological thromboprophylaxis (PTP) in patients undergoing radical cystectomy (RC) between 2004-2014 and to assess the risk of VTE across the...
pubmed: future oncology
Mon Oct 07, 2019 14:37
Dedicated Spiral Breast Computed Tomography With a Single Photon-Counting Detector: Initial Results of the First 300 Women
Objectives The aim of this study was to describe our initial clinical experiences using a dedicated spiral breast computed tomography (B-CT) with a single photon-counting detector. Materials and Methods This retrospective study was approved by the institutional review board. Examinations of 300 consecutive women undergoing B-CT were evaluated on reason of assignment for B-CT instead of mammography, detection rate of breast cancer, and quality criteria of data acquisition. Further evaluated...
Investigative Radiology - Published Ahead-of-Print
Fri Oct 04, 2019 03:00
Can the bending forward test be used to detect a diseased anterior semi-circular canal in patients with chronic vestibular multi-canalicular canalithiasis (BPPV)?
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Acta Oto-Laryngologica: Table of Contents: Taylor and Francis
Mon Oct 07, 2019 12:25
Glial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model.
Related ArticlesGlial pathology in a novel spontaneous mutant mouse of the Eif2b5 gene: a vanishing white matter disease model. J Neurochem. 2019 Oct 06;: Authors: Terumitsu-Tsujita M, Kitaura H, Miura I, Kiyama Y, Goto F, Muraki Y, Ominato S, Hara N, Simankova A, Bizen N, Kashiwagi K, Ito T, Toyoshima Y, Kakita A, Manabe T, Wakana S, Takebayashi H, Igarashi H Abstract Vanishing white matter disease (VWM) is an autosomal recessive neurological disorder...
pubmed: epilepsy treatment
Mon Oct 07, 2019 15:02
Clinical features of vitamin D deficiency in children: A retrospective analysis.
Related ArticlesClinical features of vitamin D deficiency in children: A retrospective analysis. J Steroid Biochem Mol Biol. 2019 Oct 03;:105491 Authors: Zhang X, Liu Z, Xia L, Gao J, Xu F, Chen H, Du Y, Wang W Abstract Vitamin D is very important for children's health. Previous studies have shown that vitamin D deficiency leads to a series of diseases in adults. However, pediatricians are mostly aware of rickets caused by vitamin D deficiency in children...
pubmed: epilepsy treatment
Mon Oct 07, 2019 15:02
Pharmaceutics, Vol. 11, Pages 516: Evaluation of Different Techniques for Size Determination of Drug Nanocrystals: A Case Study of Celecoxib Nanocrystalline Solid Dispersion
Pharmaceutics, Vol. 11, Pages 516: Evaluation of Different Techniques for Size Determination of Drug Nanocrystals: A Case Study of Celecoxib Nanocrystalline Solid Dispersion Pharmaceutics doi: 10.3390/pharmaceutics11100516 Authors: Kaur Parmar Bansal Celecoxib (CEL) Nanocrystalline Solid Dispersion (CEL_NCSD) was generated by spray drying CEL, mannitol (MAN) and sodium lauryl sulfate (SLS) from a solvent mixture of methanol, acetone and water. The purpose of the work was to...
Pharmaceutics
Mon Oct 07, 2019 03:00
Prostate Carcinoma Grade and Length But Not Cribriform Architecture at Positive Surgical Margins are Predictive For Biochemical Recurrence After Radical Prostatectomy
Postoperative biochemical recurrence occurs in up to 40% of prostate carcinoma patients treated with radical prostatectomy. Primary tumor grade and cribriform architecture are important parameters for clinical outcome; however, their relevance at positive surgical margins has not been completely elucidated yet. We reviewed 835 radical prostatectomy specimens and recorded pT-stage, surgical margin status, Grade Group, and cribriform architecture of the primary tumor and at positive surgical margins....
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Oct 04, 2019 03:00
Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid Fibrosarcoma
Sclerosing epithelioid fibrosarcoma (SEF) is an aggressive soft tissue sarcoma, characterized by a distinctive epithelioid phenotype in a densely sclerotic collagenous stroma, that shows frequent MUC4 immunoreactivity and recurrent gene fusions, often involving EWSR1 gene. A pathogenetic link with low-grade fibromyxoid sarcoma (LGFMS) has been suggested, due to cases with hybrid morphology as well as overlapping genetic signature. However, a small subset of SEF is negative for MUC4 and lacks the...
The American Journal of Surgical Pathology - Published Ahead-of-Print
Fri Oct 04, 2019 03:00
The psychology of the Democrats - American Thinker
The psychology of the Democrats  American Thinker
psychology - Google News
Mon Oct 07, 2019 11:19
Renowned sports psychologist captains new centre - North-West University Press Office - Mail and Guardian
Renowned sports psychologist captains new centre - North-West University Press Office  Mail and Guardian
psychology - Google News
Mon Oct 07, 2019 11:17
VCU Psychology - Group Therapy | Community Calendar - Richmond.com
VCU Psychology - Group Therapy | Community Calendar  Richmond.com
psychology - Google News
Mon Oct 07, 2019 08:22
School Psychology Professor from UC Berkeley to Speak on Friday, Oct. 11 - University of Arkansas Newswire
School Psychology Professor from UC Berkeley to Speak on Friday, Oct. 11  University of Arkansas Newswire
psychology - Google News
Mon Oct 07, 2019 08:03
On Becoming A God In Central Florida leans into its psychological horror - The A.V. Club
On Becoming A God In Central Florida leans into its psychological horror  The A.V. Club
psychology - Google News
Mon Oct 07, 2019 06:00
Psychologist: family of Kelsey Starling may still have difficult challenges ahead - WBRC
Psychologist: family of Kelsey Starling may still have difficult challenges ahead  WBRC
psychology - Google News
Mon Oct 07, 2019 05:59
How do you think about risk? The psychology behind investment decisions - BizNews
How do you think about risk? The psychology behind investment decisions  BizNews
psychology - Google News
Mon Oct 07, 2019 05:30
The Voice of Panic Attacks - Psychology Today
The Voice of Panic Attacks  Psychology Today
psychology - Google News
Mon Oct 07, 2019 04:52
The End of Sex - Psychology Today
The End of Sex  Psychology Today
psychology - Google News
Mon Oct 07, 2019 04:48
Psychology Club - Spectra
Psychology Club  Spectra
psychology - Google News
Mon Oct 07, 2019 04:47
Kids Told Lies by Parents Can Face Psychological Challenges as Adults - PsychCentral.com
Kids Told Lies by Parents Can Face Psychological Challenges as Adults  PsychCentral.com
psychology - Google News
Mon Oct 07, 2019 04:28
Innovative positive psychology curriculum places wellbeing at the centre of learning - The Sector
Innovative positive psychology curriculum places wellbeing at the centre of learning  The Sector
psychology - Google News
Mon Oct 07, 2019 02:36
Professor’s passion drives psychology program forward - The Torch
Professor’s passion drives psychology program forward  The Torch
psychology - Google News
Mon Oct 07, 2019 02:12
Uni gets nod for best psychology degree in country - Northern Star
Uni gets nod for best psychology degree in country  Northern Star
psychology - Google News
Mon Oct 07, 2019 01:00
The Bold and the Beautiful Spoilers: Douglas’ Psychological Turmoil – Thomas & Lope’s Custody Fight Makes Things Worse? - Celebrity Dirty Laundry
The Bold and the Beautiful Spoilers: Douglas’ Psychological Turmoil – Thomas & Lope’s Custody Fight Makes Things Worse?  Celebrity Dirty Laundry
psychology - Google News
Mon Oct 07, 2019 00:47
New psychology research has linked death anxiety to bedtime procrastination - PsyPost
New psychology research has linked death anxiety to bedtime procrastination  PsyPost
psychology - Google News
Sun Oct 06, 2019 21:00
Food Allergies and Relationship Stress - Psychology Today
Food Allergies and Relationship Stress  Psychology Today
psychology - Google News
Sun Oct 06, 2019 20:13
Plans to convert former psychology block for medical education - The Bangor Aye
Plans to convert former psychology block for medical education  The Bangor Aye
psychology - Google News
Sun Oct 06, 2019 18:48
The Vagus Nerve May Carry Serotonin Along the Gut-Brain Axis - Psychology Today
The Vagus Nerve May Carry Serotonin Along the Gut-Brain Axis  Psychology Today
psychology - Google News
Sun Oct 06, 2019 16:54
Putting boards onto the psychologist's couch told us nothing - The Australian Financial Review
Putting boards onto the psychologist's couch told us nothing  The Australian Financial Review
psychology - Google News
Sun Oct 06, 2019 16:00
Mental Health Services For County's Veterans Increase With Addition Of Clinical Psychologist At San Rafael Center - SFGate
Mental Health Services For County's Veterans Increase With Addition Of Clinical Psychologist At San Rafael Center  SFGate
psychology - Google News
Sun Oct 06, 2019 13:32

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